Clinical trials: Geriatric Hematology
Anemia
The Prevalence of Malaysian Children Aged ≥ 6 to ≤ 36 Months at Risk of Anaemia
The main purpose of this study is to determine the prevalence of Malaysian children aged ≥ 6 to ≤ 36 months at risk of anaemia by measuring Total Haemoglobin (SpHb) using a non-invasive haemoglobin assessment.
- Trial name
- NCT05181436
- Testing
- measuring Total Haemoglobin (SpHb) using Masimo Rad-67.
- Where
- Malaysia
- Volunteers
- 1,215 people, healthy volunteers welcome
- Sponsor
- Danone Specialized Nutrition (M) Sdn Bhd
Pediatric Cancer
Effects of Therapeutic Play on Anxiety and Fear
This study was carried out as a randomized controlled experimental study in order to evaluate the effect of therapeutic game use on anxiety and fear levels before indwelling catheter intervention in children aged 6-12 years…
- Trial name
- NCT06229327
- Testing
- THERAPEUTICGAMES
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Okan University
Anemia
Anemia in the Elderly
Eligible elderly men and women with anemia will undergo a full hematologic evaluation plus additional laboratory tests to determine the etiology of the anemia.
- Trial name
- NCT00640172
- Where
- 3 sites in United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Stanford University
Hookworm
Study to Test Whether Shoes Protect Children Against Hookworm Infection on Pemba Island, Zanzibar
Small association studies have hypothesised that shoes protect against hookworm infection. The purpose of this pragmatic study was determine, under field conditions, whether school-age children on Pemba Island, Zanzibar, would…
- Trial name
- SKIP (NCT01869127)
- Testing
- Shoes
- Where
- Tanzania
- Volunteers
- 1,056 people, healthy volunteers welcome
- Sponsor
- Bird, Christopher
Anemia
Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia
The VITamin D and OmegaA-3 TriaL (VITAL; NCT01169259) is a randomized clinical trial in 20,000 U.S. men and women studying whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil…
- Trial name
- NCT01632761
- Testing
- Vitamin D3 ., omega-3 fatty acids (fish oil)
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Neural Tube Defects, Folic Acid Deficiency
Using Iodized Salt to Improve Serum Folate, B12 and Iron Levels
Question: How effective is fortified iodized salt in increasing serum concentrations of folate, B12 and iron among non-pregnant and non-lactating women of reproductive age? Hypothesis: Micronutrient fortified iodized salt can…
- Conditions
- Neural Tube Defects, Folic Acid Deficiency, Spina Bifida, Anencephaly-Spina Bifida
- Trial name
- NCT06904612
- Testing
- Micronutrient fortified iodized salt
- Where
- 2 sites in United States, India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hydrocephalus and Neuroscience Institute
Thrombosis
A Study to Investigate Biomarkers After Single Doses of Anticoagulants in Healthy Young Male and Healthy Elderly Participants (MK-0000-216 AM1)
This is a study to investigate biomarkers after single oral doses of the anticoagulant agents dabigatran etexilate and rivaroxaban in healthy young male subjects and in healthy elderly subjects.
- Trial name
- NCT01379300
- Testing
- dabigatran etexilate, rivaroxaban
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Anemia, Iron Status
Daily and Weekly Iron Supplementation in Infants
This study aims to compare the efficacy of daily iron supplementation and weekly iron supplementation in infants aged 6-12 months on the prevalence of anemia, hemoglobin level, and serum ferritin levels.
- Conditions
- Anemia, Iron Status, Infants, Iron
- Trial name
- NCT06318858
- Testing
- Iron supplement
- Where
- Thailand
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Iron Deficiency Anemia, Anemia
Iron Fish in Dominican Republic (DR) Children
The objective of the study is to assess the acceptability, feasibility, and barriers to Lucky Iron Fish™ (LIF) utilization among families with young children in a Latin American community with a high prevalence of iron deficiency…
- Conditions
- Iron Deficiency Anemia, Anemia, Iron-deficiency
- Trial name
- NCT03199235
- Testing
- Lucky Iron Fish, enhanced standard of care
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Anemia
Single Dose Group Stratified Study in Renal Impaired and Healthy Aged and Gender Matched Subjects
Safety, tolerability, pharmacokinetics and pharmacodynamics will be investigated in a single dose group stratified study in renal impaired and healthy subjects.
- Trial name
- NCT01318551
- Testing
- BAY85-3934
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bayer
This Study Aimed to Evaluate the Impact of Fortified Biscuit Consumption on the Iron Status of School-aged Children in Rural Kaolack
Impact of the Consumption of Fortified Biscuits on the Iron Status of School-aged Children
This study aimed to evaluate the impact of fortified biscuit consumption on the iron status of school-aged children in rural Kaolack.
- Trial name
- NCT07041866
- Testing
- Fortified Biscuit with Local Iron-Rich Ingredients, Non-Fortified Biscuit
- Where
- Senegal
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Universite du Sine Saloum Elhadj Ibrahima Niasse
Acute Myeloid Leukemia (AML)
Improving Delivery of Aging-Related Supportive Care for Older Adults With Acute Myeloid Leukemia
The goal of this clinical trial is to test a way of delivering supportive care to adults 60 years and older who are starting venetoclax-based treatment for newly diagnosed acute myeloid leukemia (AML).
- Trial name
- ACTIVE DEFAULT (NCT07777471)
- Testing
- Active Default
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Menopause, Cardiac Function Impaired
Effects of Exercise Training on Cardiovascular Health in Middle-aged Women
The hypothesis of the present study is that physical training can oppose detrimental changes in cardiovascular and metabolic health associated with estrogen loss after menopause.
- Conditions
- Menopause, Cardiac Function Impaired, Cardiovascular Diseases, Blood Platelet Disorders
- Trial name
- NCT02135575
- Testing
- Spinning
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Malaria,Falciparum, Anemia
Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzania
Background: In high-transmission settings, up to 70% of school-aged children harbour malaria parasites which is mostly asymptomatic, thus, from an epidemiological point of view, they contribute significantly as reservoir to…
- Trial name
- InSMART-school (NCT03640403)
- Testing
- Dihydroartemisinin-piperaquine, Artesunate-amodiaquine
- Where
- Tanzania
- Volunteers
- 1,555 people, healthy volunteers welcome
- Sponsor
- National Institute for Medical Research, Tanzania
Acute Myeloid Leukemia
Safety and Efficacy of Venetoclax in Combination With Azacitidine and HA Regimen in the Treatment of AML in the Elderly
This is a prospective phase II, single-arm clinical study that plans to enroll 45 patients aged 60 years or older with primary AML diagnosed after April 1, 2023.The purpose of this trial is to evaluate the efficacy of Venetoclax…
- Trial name
- NCT05949762
- Testing
- Venetoclax in Combination With Azacitidine and HA Regimen
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ZePing Zhou
Multiple Myeloma
Patient and Care Partner Experiences Living With Multiple Myeloma (PaCE-MM)
This research study is explore the impact over time of multiple myeloma and its associated treatments on the physical and cognitive function and quality of life of patients and their care partners and how these impacts affect the…
- Trial name
- PaCE-MM (NCT05276622)
- Testing
- Comprehensive Geriatric Assessment, Qualitative patient-care partner interviews, Surveys on well-being and function
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Intestinal Parasitic Infections, Anaemia
Impact of Hand Hygiene Activities on the Prevention of Intestinal Parasitic Infections and Anaemia Among School Children
Impact exerted by intestinal parasitic infections is much higher in developing countries. School-aged children are at higher risk from the burden of disease, because they specially have many parasitic infections.
- Trial name
- NCT01619254
- Testing
- Hand washing with soap and hand finger nail clipping
- Where
- Ethiopia
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Mekelle University
Iron-deficiency
Effect of Vitamin D3-fortified Fruit Juice on Iron Status in Women
The present study is designed to utilise vitamin D3 supplements that may potentially act as an iron absorption enhancer to improve iron status in the Malaysian child-bearing aged women with low iron stores.
- Trial name
- NCT04618289
- Testing
- Vitamin D3-fortified fruit juice supplement
- Where
- Malaysia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Anemia, Clonal Hematopoiesis
Aging of Hematopoietic Stem Cells - Molecular Architecture of Marrow Dysplasia and Clinical Contribution of Ineffective Hematopoiesis to Frailty in the Elderly
The prevalence and incidence of anemia tend to increase with advancing age. Relatively low hemoglobin concentrations are a common laboratory finding in the elderly, for the most part judged by physicians as a sign without…
- Trial name
- NCT03907553
- Testing
- targeted genome sequencing
- Where
- Italy
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Aging
Effect of Aging on Haemostasis Parameters
Aging is an independent risk factor, without any clear explanation. The primary aim of the study is to depict the effect of aging on the coagulation fibrinolysis parameters and microparticles.
- Trial name
- NCT00299624
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hopital Lariboisière