Clinical trials: Geriatric Patient
Delirium, Cognitive Impairment
Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)
There is lack of attention to preoperative cognitive function and delirium in elderly who underwent surgery. The investigators are investigating different tools that can help to screen for cognitive dysfunction and delirium in…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Dysfunction, Cognitive Dysfunction, Postoperative
- Trial name
- NCT05209555
- Testing
- MoCA, BAMCOG, DeltaScan
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Nonvalvular Atrial Fibrillation, Health, Subjective
Pharmacokinetic Study to Evaluate Dabigatran Etexilate in Elderly Subjects
This study intends to collect blood samples of adult healthy subjects, elderly healthy subjects and elderly patients with atrial fibrillation after taking dabigatran etexilate for pharmacokinetics and other studies, aiming to…
- Trial name
- NCT05715658
- Testing
- Dabigatran etexilate capsule
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dongyang Liu
Motivational Interviewing, Health Care Seeking Behavior
The Effect of Motivational Interviewing-Based Health Behavior Training in Chronically Ill Migrant Women
This randomized controlled experimental study will be conducted to investigate the effect of health seeking behavior training based on motivational interviewing techniques on health seeking behaviors, illness self-management and…
- Conditions
- Motivational Interviewing, Health Care Seeking Behavior, Migrants, Women
- Trial name
- NCT06505707
- Testing
- Health Seeking Behavior Training Based on Motivational Interviewing Techniques
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kahramanmaraş İstiklal University
Emergencies
Optimized Acute Care for Geriatric Patients Using an Intersectoral Telemedical Cooperation Network - Around the Clock
Due to "demographic change", the composition of the population in Germany is changing. The consequence of this change is a population that is getting older on average.
- Trial name
- Optimal@NRW (NCT04879537)
- Testing
- Telemedical support
- Where
- Germany
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Hyperoxia, Delirium in Old Age
The Effect of Intraoperative Hyperoxemia on Postoperative Delirium in Geriatric Patients
Oxygen therapy is the most common treatment modality for patients with hypoxemia, but target values for normoxemia are not clearly defined. Therefore, iatrogenic hyperoxemia is a very common situation.
- Trial name
- NCT06326372
- Testing
- control, ORi+SpO2
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Hepatitis E
A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients )
This phase IV clinical study was designed to evaluate the immunogenicity and safety of Hecolin® in the chronic Hepatitis B patients on the clinical stability.
- Trial name
- NCT02964910
- Testing
- Recombinant Hepatitis E Vaccine (Escherichia Coli)
- Where
- China
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Xiamen Innovax Biotech Co., Ltd
Diabetes, Diabetes Mellitus
The Impact of the Self-efficacy Building Nursing Program on Foot Self-care Confidence and Perceived Risk of Diabetes-related Foot Complications Among Diabetic Elderly Patients: A Randomized Virtual Based Trial
Abstract Background: Diabetes-related foot complications are a major cause of morbidity among elderly patients with diabetes, often exacerbated by inadequate self-care practices and low self-efficacy.
- Conditions
- Diabetes, Diabetes Mellitus, Foot Care
- Trial name
- foot self-care (NCT06973850)
- Testing
- The Self-Efficacy Building Nursing Program
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pain Measurement, Geriatric Patients
Measuring Pain Intensity in Older Patients: A Comparison of Five Scales
Pain intensity is commonly measured in research and clinical settings.1 Different pain intensity domains can be assessed, depending on the specific goals of the researcher or clinician.
- Trial name
- NCT04555928
- Testing
- No intervention
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Postoperative Cognitive Dysfunction
The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery
The purpose of this study is to determine whether epidural levobupivacaine applied for the purpose of post-operative analgesia compared to systemic analgesia with morphine leads to better pain control, stronger suppression of the…
- Trial name
- NCT02848599
- Testing
- morphine, levobupivacaine
- Where
- Croatia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Osijek University Hospital
Postoperative Cognitive Dysfunction
Effects of Amantadine on Postoperative Cognitive Dysfunction
Post-operative cognitive dysfunction (POCD) is a fairly well-documented clinical phenomenon. Investigators will determine whether amantadine can reduce the occurrence of POCD in elderly patients with major abdominal surgery.
- Trial name
- NCT03527134
- Testing
- Amantadine
- Where
- China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Zhiyi Zuo
Lymphoma
Assessing Antibody Responsiveness to Hepatitis B Vaccine in Aged Lymphoma Patients Undergoing Treatment With Rituximab
Background: The ability of the immune system to function declines with aging. This is reflected by a marked decrease in the responsiveness to vaccinations and to infectious agents.
- Trial name
- NCT00863187
- Testing
- rituximab
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Old Age
ED50 and ED95 of Intrathecal Hyperbaric Bupivacaine With Fentanyl for Transurethral Prostatectomy in Elderly Patients
As people age, the incidence of prostate hyperplasia increases. So patients under Transurethral Resection of Prostate(TURP) or Holmium Laser Ennucleation of Prostate(HoLEP) are mostly ole age people.
- Trial name
- NCT03704441
- Testing
- Bupivacaine
- Where
- South Korea
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Geriatric Hip Fracture
'Home Sweet Home' Programme-2
Objectives: To determine the effectiveness of telerehabilitation on the quality of life and mobility of early post-discharge in hip fracture patients, and to investigate whether telerehabilitation in the form of daily TUG tests…
- Trial name
- NCT05823129
- Testing
- Tele-rehabilitation caregiver empowerment enhanced post- discharge rehabilitation directive
- Where
- Hong Kong
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hypotension on Induction
Perfusion Index as a Predictor of Postinduction Hypotension of General Anesthesia in Geriatric Patients
The influence of hemodynamic aberrations during anesthesia on adverse outcomes is an important clinical issue. There is evidence that hypotension and hypertension during general anesthesia are independently associated with…
- Trial name
- NCT04682717
- Testing
- perfusion index monitoring for postinduction hypotension
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Insomnia
Effects of Aromatherapy on Sleep Quality in Hospitalized Elderly Female Patients With Insomnia
To evaluate the efficacy and safety of standardized aromatherapy compared with placebo in improving sleep quality among hospitalized elderly female patients with insomnia.
- Trial name
- NCT07373132
- Testing
- Aromatherapy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Anhui Medical University
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
COVID-19, Pulmonary Tuberculosis
Study on Three Doses of an Inactivated COVID-19 Vaccine in Chinese Pulmonary Tuberculosis Patients
This is a randomized, double-blind, parallel-controlled study, for evaluation of safety and immunogenicity of three doses of an inactivated COVID-19 vaccine (CoronaVac) in pulmonary tuberculosis patients aged 18-75 years.
- Trial name
- NCT05148949
- Testing
- Standard dosage inactivated vaccine, Double dosage inactivated vaccine
- Where
- 6 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Alzheimer Disease, Neurofibrillary Tangle
Analysis of 18F-XTR006 PET Imaging in Cognitively Normal Subjects, and Patients With MCI and AD
The goal of this clinical trial is to evaluate the efficacy and safety of XTR006 injection PET visual reading in detecting brain neurofibrillary tangles (NFTs) in elderly subjects with Mild Cognitive Impairment (MCI), Alzheimer's…
- Trial name
- NCT07115238
- Testing
- XTR006
- Where
- China
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Sinotau Pharmaceutical Group
Colorectal Cancer
Nutrition and Exercise Program for Elderly Colorectal Cancer Patients
The goal of this interventional study is to evaluate the effect of mobile health intervention on frailty, physical fitness, physical activity, and nutritional status of elderly patients with colorectal cancer.
- Trial name
- NCT06502275
- Testing
- Mobile Health Management Frailty Care Program
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Frail Elderly Syndrome, Aging
Autologous Stem/Stromal Cellular Stromal Vascular Fraction (cSVF) In Frailty-Aging Processes
With increasing age and health issues associated with aging, many systemic cellular and structural changes are known to occur. The intent of this trial is to determine the safety and efficacy of delivery of autologous cellular…
- Conditions
- Frail Elderly Syndrome, Aging, Degenerative Disease
- Trial name
- GARM-W (NCT03514537)
- Testing
- Microcannula harvest adipose stromal tissues, Centricyte 1000, Sterile Normal Saline IV Deployment of cSVF
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Healeon Medical Inc