Clinical trials: Geriatric Patient
Frailty at Older Adults, Primary Care
Implementation of a Clinical Decision Support System in Primary Care for the Screening and Assessment of Frailty in Patients Aged 65 and Over
This observational study aims to evaluate the real-life use of a digital tool (Fragiclic) by general practitioners (GPs) and nurses to screen and assess frailty in adults aged 65 and over.
- Conditions
- Frailty at Older Adults, Primary Care, Geriatric Assessment, Implementation Research
- Trial name
- FRAGICLIC (NCT07570628)
- Where
- France
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- CNGE Conseil
Minimally Displaced Intra-articular Distal Radius Fracture
Distal Radius Fracture - Treatment Comparison
This is a prospective multi-site study. Subjects with distal radius fractures will be enrolled. Subjects will be treated surgically with a Sonoma WRx™ device or managed non-operatively with a splint or cast.
- Trial name
- NCT01883063
- Testing
- Surgical Treatment, Non surgical Treatment (Cast or splint)
- Where
- 3 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Sonoma Orthopedic Products, Inc.
Hypotension During Surgery
IV Dexamethasone in Preventing Post Spinal Hypotension
Orthopedic lower limb procedures are carried out under spinal anesthesia which involves administration of drugs in the space surrounding the spinal cord.
- Trial name
- NCT07052864
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Cholecystitis, Acute
Laparoscopic Cholecystectomy or Conservative Treatment in the Acute Cholecystitis of Elderly Patients
Cholecystectomy is the only curative treatment for gallstone disease of acute calculous cholecystitis.The purpose of this study is to find the most effective treatment (laparoscopic cholecystectomy vs.
- Trial name
- NCT02972944
- Testing
- Laparoscopic cholecystectomy, Non-operative treatment
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Hypoxemia, Eldery People
HFNC vs Conventional Oxygen During Gastrocolonoscopy in Elderly Patients
This study aims to compare high-flow nasal oxygen (HFNO) with conventional nasal cannula oxygen during sedation for combined upper and lower gastrointestinal endoscopy (gastroscopy and colonoscopy) in patients aged 75 years and…
- Conditions
- Hypoxemia, Eldery People, Endoscopy, Colonoscopy
- Trial name
- NCT07916298
- Testing
- HİGH FLOW NASAL CANNULA OXYGEN, NASAL CANNULA OXYGEN
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Dental Restoration Failure
Clinical Evaluation of Nano Hydroxyapatite Reinforced Glass Ionomer in Treatment of Root Caries in Geriatric Patients
In geriatric patients, will the clinical performance of nano hydroxyapatite reinforced glass ionomer be better than conventional glass ionomer cement in treatment of root caries lesions over one year follow up?
- Trial name
- NCT04701320
- Testing
- Conventional glass ionomer, Nano hydroxyapatite reinforced glass ionomer
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Loneliness
Interventions to Reduce Loneliness in Elderly Patients in the Cardiac ICU (CICU)
This clinical trial aims to study whether patient-tailored interventions can reduce loneliness levels in elderly patients admitted to the Cardiac ICU (CICU).
- Trial name
- NCT05764902
- Testing
- Patient-tailored intervention
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poriya Medical Center
Frail Elderly Syndrome
Subjective Factors of Polymedication in the Elderly: a Qualitative Study of the Perceptions of Patients, Relatives and Referent Physicians.(DOSAGE)
The DOSAGE Study is a qualitative transversal study aiming to describe and understand the subjective factors of polymedication in the elderly population (75 years old and more), defined as 10 simultaneous drugs.
- Trial name
- DOSAGE (NCT03309228)
- Testing
- individual interviews
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Post-Operative Delirium, Postoperative Cognitive Dysfunction
Role of Absolute Cerebral Oximetry to Prevent Neurocognitive Injury in Elderly Patients Undergoing Cardiac Surgery
The purpose of this study is to determine whether brain oxygenation measured by cerebral oximeter has an impact on neurocognitive dysfunction.
- Trial name
- NCT00991328
- Testing
- SctO2 < 60 %.
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypoxia
Integrated Pulmonary Index Monitoring on the Incidence of Hypoxemia in Elderly Patients With Painless Colonoscopy
The purpose of this clinical trial is to integrated pulmonary index to see if there is an effect on the incidence of hypoxemia during painless colonoscopy in older patients.
- Trial name
- NCT06987630
- Testing
- monitor integrated pulmonary index（IPI） and take appropriate measures
- Where
- China
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
Aging, Sarcopenia
Effect of L-arginine on Microcirculation, Myogenesis and Angiogenesis Associated With Aging, Sarcopenia and Diabetes
This study aims was evaluated the effect of L-arginine on microcirculation, vasoreactivity / endothelial function and vascular smooth muscle of young and old women with Sarcopenia or Type 2 Diabetes Mellitus measured by Nailfold…
- Conditions
- Aging, Sarcopenia, Type 2 Diabetes, Microcirculation
- Trial name
- NCT04112875
- Testing
- L-arginine, Maltodextrin
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Patients Undergoing Orthopedic Hip Surgery Under Spinal Anesthesia, Orthopedic Hip Sugery in Eldely Patients
Comparison of Norepinehrine Versus Phenylepherine Infusion for Prevention of Post-spinal Hypotension
This prospective randomized double-blinded clinical trial aims to compare the efficacy and hemodynamic effects of prophylactic norepinephrine infusion versus phenylephrine infusion for prevention of spinal anesthesia-induced…
- Trial name
- NCT07662408
- Testing
- Norepinephrine, Phenylephrine
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sohag University
Undernutrition, Malnutrition
Nutritional Risk and Nutritional Care Practices in the Hospitalized Elderly
The purpose of this study is to estimate the prevalence of nutritional risk and examine nutritional care practices in the hospitalized elderly at one large university hospital in Norway.
- Trial name
- NUTRIELD (NCT01977950)
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Cancer
Health Status Evaluation for Cancer Survivors by Non-intrusive Sensing System
To improve quality of life of elderly cancer survivors 1. Using physical activity and environmental sensing technology 2. Monitoring physiological indicators of cancer recurrence Analyzing the patient's circadian rhythm, frailty…
- Trial name
- NCT02175823
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Delirium in Old Age, Fragility Fracture
Use of Anesthetic Block for the Prevention of in Hospital Delirium in Patients of the Orthogeriatric Clinical Care Center of the HUFSFB and HUSJI From 2019 - 2020
The purpose of this study is to identify the association between analgesic management with blockade of the iliac fascia versus intravenous analgesia with the presence of delirium during hospital stay in patients admitted to the…
- Conditions
- Delirium in Old Age, Fragility Fracture, Hip Fractures
- Trial name
- NCT04654962
- Testing
- Anesthetic nerve block
- Where
- Colombia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Dental Caries (Diagnosis), Diagnostic Imaging
Diagnostic Performance and Children's Acceptance of Near-Infrared Light Transillumination and Bitewing Radiographs for Detecting Proximal Cavitation in Primary Molars of Patients Aged 4 to 10 Years
The goal of this observational study is to compare the diagnostic performance of three detection methods for approximal carious lesions in primary molars among pediatric patients aged 4-10 years.
- Conditions
- Dental Caries (Diagnosis), Diagnostic Imaging, Optical Imaging, Radiographic Image Interpretation, Computer-Assisted
- Trial name
- NILT (NCT07041164)
- Testing
- Bitewing radiograph, Near-infrared light transillumination
- Where
- 2 sites in Thailand
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Sawanya Prutthithaworn
Influenza, Human, Pneumococcal Infections
Influenza Vaccine and Pneumococcal Vaccine
Previous studies have demonstrated the immunogenicity and safety of the co-administration of the trivalent inactivated influenza vaccine (IIV3) with the polysaccharide pneumococcal vaccine (PPV) or pneumococcal conjugate vaccine…
- Trial name
- NCT02582047
- Testing
- Influenza vaccination with PPV23, Influenza vaccination with PCV13
- Where
- 2 sites in South Korea
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Demoralization
Effects of a Five-Dimensional Intervention Program Based on Inner Strength on Demoralization Syndrome in Elderly Cancer Patients
From January 2025 to January 2026, a total of 66 elderly cancer patients with demoralization syndrome who were hospitalized in the Department of Internal Medicine at Peking Union Medical College Hospital were enrolled.
- Trial name
- NCT07625904
- Testing
- psychological support
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Urological Surgery
ED90 of Teglidine for Suppressing LMA Insertion Response in the Elderly
This research protocol aims to investigate the 90% effective dose (ED90) of taiglididine for inhibiting laryngeal mask insertion response in elderly patients.
- Trial name
- NCT07096115
- Testing
- Taiglididine
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
Pneumococcal Infections
Immunogenicity After Revaccination With 23-valent Pneumococcal Polysaccharide Vaccine: Healthy Elderly People Versus Diabetic Patients
Pneumococcal disease causes thousands of infections, such as meningitis, bloodstream infections, pneumonia, and ear infections in US annually.
- Trial name
- NCT04875858
- Testing
- ProDiax-23 (PPSV23)
- Where
- South Korea
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital