Clinical trials: Geriatric Patient
Postoperative Delirium
Comparison of DRS-R-98 and 3D-CAM in the Assessment of Postoperative Delirium in Elderly Patients
Postoperative delirium (POD) is a transient and usually fully reversible altered state of consciousness that develops acutely or subacutely after surgery, characterized by widespread, daily fluctuations in brain metabolism and…
- Trial name
- NCT05992818
- Testing
- comparing DRS-R-98 (The Delirium Rating Scale--Revised-98) and 3D-CAM (3-minute diagnostic assessment for CAM-Confusion Assessment Method-defined delirium) tests to assess postoperative delirium
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Nasopharyngeal Carcinoma
Nimotuzumab Combined With VMAT in Elderly Patients With Nasopharyngeal Carcinoma
To evaluate the efficacy and toxicity of Nimotuzumab combined with VMAT in the treatment of elderly patients with nasopharyngeal carcinoma (> 70 years old), and to provide high-level clinical evidence for the optimal treatment of…
- Trial name
- NCT03915132
- Testing
- Nimotuzumab, VMAT
- Where
- China
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Colorectal Neoplasms
Risk-adapted Screening in First-degree Relatives of Patients With Colorectal Cancer
BACKGROUND: First-degree relatives of patients with colorectal cancer are at increased risk for colorectal cancer as well. Nevertheless, participation in the German national screening program stagnates at 2-3 percent per year…
- Trial name
- FAMKOL (NCT01903395)
- Testing
- Nurse-led counselling
- Where
- 33 sites in Germany
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Older Patients Dying in Acute Geriatric Hospital Wards
The Effectiveness of the Care Programme for the Last Days of Life
BACKGROUND Demographic trends coupled with a rise in chronic diseases mean that the population of patients requiring palliative and end-of-life care is ageing.
- Trial name
- PLaDays (NCT01890239)
- Testing
- Care Programme for the Last Days of Life
- Where
- 9 sites in Belgium
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- End-of-Life Research Group
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Understanding Needs of Older Patients Prior to Starting Cancer Treatment
A geriatric assessment (GA) is a structured approach to identifying and addressing the strengths and vulnerabilities of older adults with cancer.
- Trial name
- PGA (NCT07225920)
- Testing
- Survey Administration, Interview, Educational Intervention
- Where
- 42 sites in United States, Puerto Rico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Geriatric Patients
Pilot Study: Complementary Therapies in Geriatric Patients
In a randomized controlled pilot study the investigators include geriatric patients living in a geriatric residential community. Two interventions are compared: 1.
- Trial name
- NCT00974506
- Testing
- CAM-intervention, Routine care therapy
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Alzheimer's Disease
Biomarker Study for Alzheimer's Disease
The study aims to identify immune biomarkers in peripheral blood for identifying Alzheimer's disease (AD). Blood samples from subjects with AD will be compared to age-matched controls without cognitive symptoms, as well as…
- Trial name
- BiomarkerAD (NCT02472899)
- Testing
- Blood sample
- Where
- Israel
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Beersheva Mental Health Center
Chronic Obstructive Pulmonary Disease
Combined Effects of Blow Bottle Device and Postural Drainage in Moderate to Severe Elderly COPD Patients
It will be a randomized clinical trial. Age of selected subjects will be between 40 to 70 years. Data will be collected from Wazirabad institute of cardiology. There will be 2 groups i.e.
- Trial name
- NCT06476769
- Testing
- blow bottle technique, percussion
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Geriatric, General Anesthesia Induced Hypotension
What Causes Low Blood Pressure After Anesthesia in Older Adults Having Non-Heart Surgery ?
The purpose of this study is to identify risk factors contributing to post-induction hypotension in geriatric patients undergoing elective non-cardiac surgery under general anesthesia at Dr.
- Conditions
- Geriatric, General Anesthesia Induced Hypotension, Elective Surgery, Hypotension
- Trial name
- GERIHYPO (NCT07019805)
- Testing
- Standard General Anesthesia Induction Using Propofol, Fentanyl and Midazolam, Blood Pressure Continous Monitoring, syrnge pump for the anesthesia agent, and vasoconstrictor drug
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
T-Cell Dysfunction, Chemotherapy Effect
Studying the Senescent T Cell Features and Its Relationship with the Chemotherapy Efficacy in Young TNBC
The goal of this observational study is to learn about the features of senescent T lymphocytes induced by chemotherapy and its relationship with the efficacy of neoadjuvant chemotherapy in young triple-negative breast cancer…
- Conditions
- T-Cell Dysfunction, Chemotherapy Effect, Adverse Events
- Trial name
- STFREiYTNBC (NCT06684054)
- Testing
- docetaxel, anthracycline, cyclophosphamide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Patient Fall
Intervention to Reduce Falls Incidence
The purpose of this study is to determine the effectiveness of a multifactorial intervention program to prevent falls among the elderly as compared to a brief intervention.
- Trial name
- EPICA (NCT01279525)
- Testing
- multifactorial
- Where
- Spain
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Andalusian Regional Ministry of Health
Acute Myeloblastic Leukemia
Determination of Epigenetic Markers of Acute Myeloblastic Leukemia in Elderly Patients
The main objective of this study is to identify epigenetic markers specific to abnormal myeloid cells in patients with acute myeloid leukemia (AML) by analyzing the methylation of circulating cell-free DNA in plasma.
- Trial name
- LAMME (NCT07250217)
- Testing
- Epigenetic markers
- Where
- 2 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
GI Cancer, Lymphoma
Geriatric Communication Skills Training Program for Oncology Clinicians
The purpose of this study is to learn more about the effects of a training program designed to help doctors communicate better with older patients and their caregivers.
- Conditions
- GI Cancer, Lymphoma, GU Cancer, Bone Marrow Transplant
- Trial name
- NCT03530969
- Testing
- Self-Efficacy Assessment, UCLA Geriatrics Attitudes Scale, Course Evaluations
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Fibromyalgia, Old Age; Debility
Frequency of Fibromyalgia Syndrome in Elderly Patients Aged 80 and Above and Its Relationship With Geriatric Parameters
The aim of this study was to determine the prevalence of fibromyalgia syndrome in patients aged 80 years and over and to examine the relationship between detailed geriatric assessment parameters and fibromyalgia syndrome.
- Trial name
- NCT06969716
- Testing
- Detailed geriatric assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Sultan 1. Murat State Hospital
Early Recovery in Elderly Patients, Cognitive Function
Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled Non-Cardiac Surgery
The goal of this clinical study is to compare the effects of desflurane versus sevoflurane on early postoperative recovery and cognitive function in elderly patients (aged 60 years and older, ASA I-III) undergoing elective…
- Trial name
- NCT07289945
- Testing
- Sevoflurane, Desflurane
- Where
- Tunisia
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hopital Charles Nicolle
Fracture Neck of Femur
Functional Outcome After Arthroplasty
Bipolar hemiarthroplasty (BA) has long been the preferred treatment and is performed in most fracture neck of femur (FNF) cases. It is justified by the reasonable operative time, low blood loss and acceptable functional outcomes.
- Trial name
- NCT04680572
- Testing
- arthroplasty
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Multiple Myeloma
Patient and Care Partner Experiences Living With Multiple Myeloma (PaCE-MM)
This research study is explore the impact over time of multiple myeloma and its associated treatments on the physical and cognitive function and quality of life of patients and their care partners and how these impacts affect the…
- Trial name
- PaCE-MM (NCT05276622)
- Testing
- Comprehensive Geriatric Assessment, Qualitative patient-care partner interviews, Surveys on well-being and function
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Dexamethasone, Urologic Endoscopic Surgery
Effect of Intrathecal Dexamethasone on Intra-operative Hemodynamic in Elderly Patients Undergoing Urologic Endoscopic Surgery
Correction of Post-spinal anesthesia hypotension by fluids pose the risk of volume overload or compromising cardiac conditions. Intravenous Dexamethasone in some studies is used to treat conditions manifested by decrease of…
- Trial name
- NCT05549895
- Testing
- Dexamethasone, Bupivacaine Hydrochloride
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anesthesia, Cognitive Dysfunction
Evaluation of Cognitive Functions by Cerebral Pulse Oximetry
General and Spinal Anesthesia can be used in geriatric patients in orthopedic surgery. Post-op cognitive dysfunction can be seen in orthopedic surgeries in this group of patients.
- Trial name
- NCT03827083
- Testing
- cerebral pulse oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital