Clinical trials: Geriatric Patient
Elderly, Hypertension
Unsupervised Physical Activity in Elderly
To evaluate safety and the effects of a unsupervised physical activity program (USPAP) over blood pressure (BP), physical fitness (PF) and quality of life (QL) of elderly hypertensive patients.
- Conditions
- Elderly, Hypertension, Physical Conditioning
- Trial name
- NCT02976506
- Testing
- Unsupervised exercise program, Physical fitness and quality of life
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Patients Hospitalised in Geriatrics
E-vone® Use Detect Falls Among hOspitalized Patients in geRiAtric Medicine
This study evaluates the usability of a new remote warning system for fall in old people. This system is integrated in a shoe. Patients hospitalized in a geriatric ward but also their informal and professional caregivers will…
- Trial name
- EDORA (NCT04067193)
- Testing
- usability survey
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Elderly Women
Telerehabilitation on Physical and Mental Health of the Elderly in the Covid-19 Pandemic Context
Introduction: Due to the COVID-19 pandemic scenario, social distancing has become the main strategy to contain this pandemic, causing negative impacts on the physical and mental health of the elderly population.
- Trial name
- NCT05465811
- Testing
- Program of physical exercises and health education by telerehabilitation
- Where
- Brazil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Paulista University
Amyloid Cerebral Angiopathy, Alzheimer Disease
Florbetaben as an Amyloid Plaque Marker in Elderly Patients With Focal or Disseminated Superficial Hemosiderosis
The main objective of this study is to compare the distribution of Florbetaben (NEURACEQ: FBB) in the brain in amyloid cerebral angiopathy (ACA) manifested by isolated hemosiderosis in non-demented patients with that observed in…
- Trial name
- FBB ACC (NCT02664571)
- Testing
- Pet scan with FBB, MRI scan, APO E genotyping
- Where
- 2 sites in France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Alzheimer's Disease
A Study to Assess Regional Cerebral Blood Flow as an Alzheimer's Disease Biomarker Compared to Positron Emission Tomography in Patients With Mild-to-Moderate Alzheimer's Disease and Cognitively Normal Elderly Subjects (Study MK-0000-068)(COMPLETED)
The aim of the study is to determine if regional cerebral blood flow, measured by dynamic arterial spin labeling (dASL), can be a biomarker for stage of Alzheimer's disease.
- Trial name
- NCT00757939
- Testing
- MRI, FDG-PET
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Alzheimer's Disease, Healthy Non-elderly and Elderly Adults
Multiple Ascending Dose Safety, Tolerability, PK Study of AL001 in Alzheimer's Disease Patients & Healthy Adult Subjects
This is a Phase 1/2a, multi-center, placebo-controlled, double-blinded, randomized, multiple ascending dose (MAD) clinical trial to determine the safety and maximum tolerated dose of AL001.
- Trial name
- "MAD" (NCT05363293)
- Testing
- AL001
- Where
- 2 sites in United States, Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Alzamend Neuro, Inc.
Delirium - Postoperative, Delirium and Post-operative Cognitive Dysfunction (POCD)
Audio-Recorded Messages Delivered Via iPad to Prevent Delirium in Hip Fracture Patients
The goal of this pilot clinical trial is to learn if personalized audio-recorded reorientation messages can be successfully implemented in general hospital wards for elderly patients after hip fracture surgery.
- Conditions
- Delirium - Postoperative, Delirium and Post-operative Cognitive Dysfunction (POCD), Delirium, Postoperative
- Trial name
- NCT07396532
- Testing
- Audio-Recorded Reorientation Intervention
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Aged, Microsurgery
Microsurgery in the Elderly in a Private Practice Setting
This study reports the experience in free tissue transfer in the elderly population by a single surgeon in the private practice setting in Mexico city and the potential criticism that could arise from adverse events in…
- Trial name
- NCT04584723
- Testing
- Observation of flap survival and complications
- Where
- Mexico
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Hospital Angeles del Pedregal
Delirium - Postoperative, Opioid-Free Anaesthesia
Effect of Opioid-free Anaesthesia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery
Background Postoperative delirium (POD) is a common acute and transient form of brain dysfunction in elderly patients following surgery that can lead to serious adverse clinical outcomes and even death.
- Trial name
- NCT06958393
- Testing
- Dexmedetomidine, Esketamine, Esmolol
- Where
- China
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Asherman's Syndrome, Thin Endometrial Lining
Senescent Endometrial Cells in Patients With Thin Endometrial Lining
The goal of this observational study is to determine if thin endometrial lining that is unresponsive to estrogen might be associated with the presence of senescent cells in patients following long-term use of oral contraceptives.
- Conditions
- Asherman's Syndrome, Thin Endometrial Lining, Cell Senescence
- Trial name
- NCT06450301
- Testing
- Endometrial Biopsy
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Trio Fertility
Osteoarthritis, Hip, Arthropathy of Hip
Evaluation of Cemented and Cementless Fixation of Dual-mobility Hip Prosthesis in Elderly Patients With Osteoarthritis
The aim of this project is to investigate prosthesis fixation in the bone, respectively cemented and uncemented operation method of Avantage® dual-mobility acetabular cup in elderly patients, wear of the plastic in dual-mobility…
- Trial name
- NCT02404727
- Testing
- cup fixation, Avantage® Cup
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Postoperative Delirium, Postoperative Pain, Acute
Postoperative Delirium and Analgesia in Elderly Patients
This study aims to evaluate the effects of different postoperative analgesic approaches on postoperative delirium in elderly patients undergoing total knee arthroplasty.
- Trial name
- NCT07849517
- Testing
- adductor canal block and biFes block including bupivacain, Periarticular infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Healthy, Mild Cognitive Impairment
Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
Previous studies showed that anodal tDCS applied over the dorsolateral prefrontal cortex (DLPFC) improved episodic memory performance, indicating a possible use as an intervention for patients suffering from memory impairments.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03227185
- Testing
- real anodal transcranial direct current stimulation (tDCS)
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Sedation Complication, EBUS Guided Transbronchial Needle Aspiration
The Decisiveness of MFI-11 in Predicting Complications in Patients > 65 Years Who Underwent EBUS-TBNA Under Sedation
The aim is to evaluate the feasibility of MFI-11, one of the comprehensive frailty tests, before EBUS-TBNA. The secondary aim is to evaluate the usefulness of MFI-11 in predicting complications in risk assessment before EBUS-TBNA.
- Conditions
- Sedation Complication, EBUS Guided Transbronchial Needle Aspiration, Monitored Anesthesia Care, Elderly Patients
- Trial name
- NCT06174168
- Testing
- Modified Frailty Index -11
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Delirium
Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)
Many individuals experience an acute change in thinking and reasoning skills after surgery. This is called post-operative delirium (PD). PD symptoms typically start 1-3 days after surgery.
- Trial name
- NCT02230605
- Testing
- Mini-Mental State Examination, Self-Administered Gerocognitive Examination, Geriatric Depression Scale
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Spinal Anaesthesia, Bladder Tumor
A Retrospective Analysis of Spinal Anaesthesia for TURBT Procedures in Elderly Patients
The aim of the study was to evaluate the safety and effectiveness of spinal anesthesia among elderly patients The basic methods for diagnosis and management of bladder cancer include endoscopic procedures (cystoscopy…
- Conditions
- Spinal Anaesthesia, Bladder Tumor, Transurethral Resection
- Trial name
- NCT03221829
- Where
- Poland
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Delirium - Postoperative
The Effect of Aromatherapy on Delirium in Critically Elderly Patients Undergoing Fracture Surgery
The aim of this quasi-experimental study was to examine the effect of lavender aromatherapy on delirium in patients who underwent fracture surgery, were in intensive care, and were over 60 years old.
- Trial name
- NCT06772129
- Testing
- Aromatherapy
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Senay Gokdemir
Geriatric, Performance
Clinical Performance of Zirconia Reinforced GI Versus Conventional Viscous GI in Geriatric Patients
This study is conducted to evaluate the clinical performance of Zirconomer Improved GI restoration compared to Conventional viscous GI restoration in geriatric patients with Posterior carious lesions in class I or II cavities
- Trial name
- NCT04298151
- Testing
- Zirconomer Improved, Ketac Molar quick Aplicap
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Elderly ; Moderate Risk Surgery
Optimized Anesthesia to Reduce Postoperative Cognitive Impairment in the Elderly
The aim of this study is to demonstrate that in elderly and frail patients, a narrower control of intraoperative blood pressure (BP) by the use of a continuous and noninvasive BP monitoring, coupled with an adequate depth of…
- Trial name
- NCT02698982
- Testing
- Depth of anesthesia monitoring (BIS, Covidien USA) and Continus non invasive blood pressure monitoring (Clearsight, Edwards LifeScience, USA), moderate risk surgery
- Where
- Belgium
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital