Clinical trials: Geriatric Patient
Hypercholesterolemia, Physical Performance
CoQ10 in Statin-associated Asthenia
This was a double-blind, randomized, placebo-controlled clinical study aiming to assess the effects of supplementation with CoQ10 phytosome on physical performance in older adults with self-reported statin-associated asthenia.
- Trial name
- NCT06391606
- Testing
- Coenzyme Q10
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Geriatric Patients
Antibacterial Effect of Probiotic Yogurt Compared to Xylitol
This study will be conducted to evaluate the antibacterial effect of probiotic bacteria in yogurt in decreasing streptococcus mutans count in saliva and plaque, decreasing bacterial adherence and increasing salivary pH compared…
- Trial name
- NCT03889015
- Testing
- Probiotic yogurt, xylitol chewing gum
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Parkinson's Disease
Effect of Stimulus Rate on Cognitive and Motor Activity in Young Subjects, Elderly Subjects, and Patients With Parkinson's Disease
The purpose of this study is to investigate how changes in the brain associated with Parkinson's disease influence the control of motor and thinking speed.
- Trial name
- NCT00026598
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acute Pain
Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain
The purpose of this research study is to determine which opiate pain medication (morphine or hydromorphone (Dilaudid)) is more effective in the treatment of acute pain in patients presenting to the emergency department.
- Trial name
- NCT00305058
- Testing
- Morphine, Hydromorphone
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Elderly Patients, Cancer Surgery
Targeted Temperature Management on Delayed Neurocognitive Recovery in Older Patients After Major Cancer Surgery
With aging population, more older patients will receive major surgery for cancer. Older patients are at increased risk of postoperative neurocognitive complications including delayed neurocognitive recovery (dNCR), which is…
- Conditions
- Elderly Patients, Cancer Surgery, Hypothermia, Accidental, Targeted Temperature Management
- Trial name
- NCT07655687
- Testing
- Target temperature management, Routine thermal management
- Where
- 2 sites in China
- Volunteers
- 1,512 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Diabetes Mellitus, Type 2, Cognitive Impairment
Diabetes and Cognitive Functions in Middle Age
This study will examine the effects of type II diabetes on cognitive functions and mood in middle-aged patients. In addition, the association between cognitive functions and glycemic controls is studied in patients.
- Conditions
- Diabetes Mellitus, Type 2, Cognitive Impairment, Hyperglycemia, Hypoglycemia
- Trial name
- DBC (NCT05919927)
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Dental Restoration Failure
Clinical Evaluation of Nano Hydroxyapatite Reinforced Glass Ionomer in Treatment of Root Caries in Geriatric Patients
In geriatric patients, will the clinical performance of nano hydroxyapatite reinforced glass ionomer be better than conventional glass ionomer cement in treatment of root caries lesions over one year follow up?
- Trial name
- NCT04701320
- Testing
- Conventional glass ionomer, Nano hydroxyapatite reinforced glass ionomer
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mobile Applications, Mobile Health
Use of Smartphone Health Applications Among Patients Aged 18 to 69 Years Recruited in Primary Care in Grenoble Area
This study evaluates the frequency of use of smartphone health applications among people consulting in primary care in the Grenoble region, France.
- Trial name
- Smartcheck (NCT03351491)
- Where
- 13 sites in France
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- University Grenoble Alps
Spinal Anesthesia Induced Hypotension, Geriatric
Internal Jugular Vein Ultrasound for Predicting Hypotension in Geriatric Patients Undergoing Spinal Anesthesia
Spinal anesthesia-induced hypotension is a common and clinically significant complication in geriatric patients. Accurate preoperative assessment of intravascular volume status may help identify patients at risk.
- Conditions
- Spinal Anesthesia Induced Hypotension, Geriatric, Internal Jugular Vein, Ultrasonography
- Trial name
- IJV-SPINAL (NCT07411313)
- Testing
- Not applicable- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Fall, Old Age; Debility
The Turkish Version of the Survey of Activities and Fear of Falling in the Elderly
The Survey of Activities and Fear of Falling in the Elderly (SAFE) was originally developed in English to determine the level of fear of falling and its interactions with activities of daily living.
- Conditions
- Fall, Old Age; Debility, Fear, Activity, Motor
- Trial name
- NCT04139109
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Alzheimer Disease, Neurofibrillary Tangle
Analysis of 18F-XTR006 PET Imaging in Cognitively Normal Subjects, and Patients With MCI and AD
The goal of this clinical trial is to evaluate the efficacy and safety of XTR006 injection PET visual reading in detecting brain neurofibrillary tangles (NFTs) in elderly subjects with Mild Cognitive Impairment (MCI), Alzheimer's…
- Trial name
- NCT07115238
- Testing
- XTR006
- Where
- China
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Sinotau Pharmaceutical Group
Motivational Interviewing, Health Care Seeking Behavior
The Effect of Motivational Interviewing-Based Health Behavior Training in Chronically Ill Migrant Women
This randomized controlled experimental study will be conducted to investigate the effect of health seeking behavior training based on motivational interviewing techniques on health seeking behaviors, illness self-management and…
- Conditions
- Motivational Interviewing, Health Care Seeking Behavior, Migrants, Women
- Trial name
- NCT06505707
- Testing
- Health Seeking Behavior Training Based on Motivational Interviewing Techniques
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kahramanmaraş İstiklal University
Patients Hospitalised in Geriatrics
E-vone® Use Detect Falls Among hOspitalized Patients in geRiAtric Medicine
This study evaluates the usability of a new remote warning system for fall in old people. This system is integrated in a shoe. Patients hospitalized in a geriatric ward but also their informal and professional caregivers will…
- Trial name
- EDORA (NCT04067193)
- Testing
- usability survey
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Exhaustion, Geriatric Disorder
Nursing Follow up in Geriatric Oncology : Tracking Time of Caregiver Exhaustion Risk
In geriatric oncology, caregivers are submitted to a risk of exhaustion. To investigate the clinical risk factor of exhaustion, the researchers propose to conduct a prospective observational study during 6 months phone follow up…
- Trial name
- TANGO (NCT02551965)
- Testing
- Phone nursing follow-up
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Geriatric Patients, Neurological Disorder
Personalized Motor Learning in Primary Care Physiotherapy (TREAT)
Over the last decade many scientific articles have been published on motor learning in neurological and geriatric rehabilitation.
- Trial name
- NCT06390800
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Zuyd University of Applied Sciences
Mild Cognitive Impairment
Real-time fMRI Neurofeedback in Patients With MCI
Increased activity in the hippocampus (i.e., hyperactivity) during a fMRI memory task was found in patients with Mild Cognitive Impairment due to Alzheimer's disease (MCI).
- Trial name
- NCT04020744
- Testing
- real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area
- Where
- 2 sites in Switzerland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Bern
Colorectal Cancer
Colorectal Cancer Screening French Organizations for the Follow-up After Colonoscopy
France is one of the European countries where the incidence of colorectal cancer is the highest among cancers for both sexes. Fecal occult blood screening has been implemented since 2008.
- Trial name
- Tempo-colo (NCT03383367)
- Testing
- Tempo Colo
- Where
- France
- Volunteers
- 33,000 people, healthy volunteers welcome
- Sponsor
- Association pour le Dépistage Organisé des Cancers dans le Rhône
Alzheimer's Disease, Healthy Non-elderly and Elderly Adults
Multiple Ascending Dose Safety, Tolerability, PK Study of AL001 in Alzheimer's Disease Patients & Healthy Adult Subjects
This is a Phase 1/2a, multi-center, placebo-controlled, double-blinded, randomized, multiple ascending dose (MAD) clinical trial to determine the safety and maximum tolerated dose of AL001.
- Trial name
- "MAD" (NCT05363293)
- Testing
- AL001
- Where
- 2 sites in United States, Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Alzamend Neuro, Inc.
Patient Compliance
Cognitive Regulation Training and Exercise Trial
The purpose of this double-blinded, randomized controlled study is to compare CORTEX (Cognitive Regulation Training and Exercise), a multi-faceted, center- and home-delivered- general and exercise-specific-active and traditional…
- Trial name
- CORTEX-II (NCT03124667)
- Testing
- Games, Videos
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign