Clinical trials: Gerontology
Accidental Falls
Evaluation of a Balance-recovery Specific Falls Prevention Exercise Program
This study aims to investigate the potential to train compensatory stepping and grasping reactions for the prevention of falls.
- Trial name
- NCT00187317
- Testing
- Balance training (exercise), Flexibility and relaxation exercise
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke Geriatrics Acute Coronary Syndrome Orthogeriatric
Medico-economic Analysis of Clinical Pharmacy Activities
In recent years, the deployment of clinical pharmacy activities in France has undergone rapid change as a result of the work carried out by the French Society of Clinical Pharmacy (SFPC), organisational innovations (iatrogenic…
- Trial name
- COD-AMAP (NCT07133152)
- Testing
- Adverse events
- Where
- 6 sites in France
- Volunteers
- 240 people
- Sponsor
- Hospices Civils de Lyon
Adverse Drug Events, Adverse Drug Reactions
YouScript IMPACT Registry
This multicenter observational study aims to investigate the benefits of providing pharmacogenetic testing with the YouScript Personalized Prescribing System which includes a clinical decision support tool and individualized…
- Conditions
- Adverse Drug Events, Adverse Drug Reactions, Drug Interaction Potentiation, Drug Metabolism, Poor, CYP2D6-RELATED
- Trial name
- IMPACT (NCT02191358)
- Where
- 7 sites in United States
- Volunteers
- 800 people
- Sponsor
- Genelex Corporation
Frailty, Geriatrics
Combating Hospital-related Function Decline Among Prefrail Older Adults: A Pilot Study
This study focuses on the "Strength-based Tailored-Exercise Program at Home (STEP@Home)" aimed at improving health outcomes for geriatric patients at risk of hospitalization-associated functional decline.
- Trial name
- STEP@Home (NCT06191276)
- Testing
- STEP@Home Intervention, Usual care
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Social Isolation, Loneliness
COVID-19 and Social Isolation and Loneliness Trial
Social isolation and loneliness worsen older peoples' quality of life, risk of dementia, and contributes to 45,000 deaths/year in Canada - as much as smoking.
- Conditions
- Social Isolation, Loneliness, Geriatric
- Trial name
- SIL (NCT05228782)
- Testing
- HOW R U? Intervention
- Where
- Canada
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Educational Problems, Nursing Caries
Web-based Educational Program Promoting
Elderly abuse is a pervasive and concerning issue, particularly as the global population ages. Gerontological nurses play a pivotal role in identifying, preventing, and responding to elder abuse.
- Trial name
- web-based (NCT06213025)
- Testing
- web-based Educational program promoting response and willingness to handle elderly
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Sarcopenia in Elderly, Frailty
Safety and Efficacy of Isomyosamine in Reducing Inflammation and Treating Muscle Loss in Older Adults After Hip or Thigh Bone Fractures
This Phase II clinical study investigates the safety and effectiveness of a new drug, Isomyosamine, in patients with sarcopenia or frailty, conditions associated with aging and muscle weakness.
- Conditions
- Sarcopenia in Elderly, Frailty, Frailty/Sarcopenia, Frailty in Older Adults
- Trial name
- NCT06942182
- Testing
- Isomyosamine 250mg
- Volunteers
- 60 people
- Sponsor
- TNF Pharmaceuticals, Inc.
COVID-19
Geriatric Population COVID-19 Observational Study (GEROCOVIDobs)
The GeroCovid e-Registry is a European de-identified clinical data electronic registry of geriatric patients at risk or suffering from COVID-19 (suspected and confirmed cases) observed since 1st March 2020 in the participating…
- Trial name
- GEROCOVIDobs (NCT04379440)
- Where
- 7 sites in Italy
- Volunteers
- 1,500 people
- Sponsor
- Raffaele Antonelli Incalzi
Musculoskeletal Pain, Physical Performance
Kinesiophobia and Physical Function in Elderly With Musculoskeletal Pain
This study aims to investigate how kinesiophobia (fear of movement), pain intensity, and physical performance are related in older adults experiencing musculoskeletal pain.
- Conditions
- Musculoskeletal Pain, Physical Performance, Geriatrics, Kinesiophobia
- Trial name
- NCT07272876
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Depression
Buprenorphine for Late-Life Treatment Resistant Depression
The goals of this pilot study are to gather data about the safety and clinical effect of low-dose buprenorphine in older adults with treatment resistant depression.
- Trial name
- BUILD (NCT01071538)
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pittsburgh
Education, Geriatrics
European Postgraduate Training in Geriatric Medicine
The objective of the study is to give a structured update on geriatric postgraduate education throughout Europe. The study will be performed as a cross-sectional structured quantitative online survey with qualitative comments.
- Trial name
- NCT02377908
- Testing
- Online Survey
- Where
- Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Klinikum Nürnberg
Hip Surgery, Rehabilitation Program
Digitally Assisted Rehabilitation at Home for Older Adults After Hip Surgery (GRIMSEL)
The goal of this clinical trial is to learn if a 12-week digitally supported, multimodal home rehabilitation program using the medical application Akina is as effective compared to routine care regarding functional independence…
- Conditions
- Hip Surgery, Rehabilitation Program, Geriatrics Rehabilitation, Digital Health Intervention
- Trial name
- GRIMSEL (NCT07658664)
- Testing
- Digitally supported multimodal rehabilitation program, routine care
- Volunteers
- 66 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Geriatrics
Impact of a Transitional Care Program on 30-Day Hospital Readmissions for Elderly Patients Discharged From a Short Stay Geriatric Ward
In France, it has be estimated that the hospital readmission rate within 30 days of patients aged 75 or older is 14% (IC95% [12.0-16.7]), nearly a quarter being avoidable.
- Trial name
- PROUST (NCT02421133)
- Testing
- Transitional care program., standard care program
- Where
- 9 sites in France
- Volunteers
- 630 people
- Sponsor
- Hospices Civils de Lyon
Geriatrics Rehabilitation
Comparing of Supervised and Unsupervised Home-Based Modified Poco-Poco Exercise in Elderly
This study comparing 2 group of intervention which are supervised home-based therapy (intervention group) and unsupervised home-based therapy (control group) using a modified poco-poco exercise program as the home-based therapy.
- Trial name
- NCT07029308
- Testing
- Modified poco-poco exercise program as the home-based therapy (Intervention)
- Where
- 2 sites in Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Padjadjaran
Chronic Kidney Disease (CKD), Elderly
Sertraline and the Risk of Serious Adverse Events
The goal of this population-based cohort study is to assess the safety of initiating a new outpatient prescription of 50 mg/day of Sertraline, a higher dose, compared to 25 mg/day, a lower dose, in adults aged 65+ with low kidney…
- Conditions
- Chronic Kidney Disease (CKD), Elderly, Outpatient
- Trial name
- NCT07387120
- Testing
- Sertraline 50 mg, Sertraline 25 mg
- Where
- Canada
- Volunteers
- 6,893 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Geriatrics
Efficacy of Samsung GEMS-H Device Training in Older Adults
The purpose of this study is to evaluate the feasibility of using Samsung robotic hip assist-based mobility intervention for older adults with frailty.
- Trial name
- NCT05197127
- Testing
- exoskeleton-based gait training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Alzheimer's Disease
Biomarker Study for Alzheimer's Disease
The study aims to identify immune biomarkers in peripheral blood for identifying Alzheimer's disease (AD). Blood samples from subjects with AD will be compared to age-matched controls without cognitive symptoms, as well as…
- Trial name
- BiomarkerAD (NCT02472899)
- Testing
- Blood sample
- Where
- Israel
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Beersheva Mental Health Center
Geriatric, Elderly
Comparison of Hand Grip Strength in Different Shoulder Positions in Geriatric Individuals: Position-Dependent Strength Analysis
The aim of this study is to examine the relationship between hand grip strength, measured in different shoulder positions, and upper extremity muscle strength, and to reveal the clinical significance of position-dependent…
- Trial name
- NCT07562854
- Testing
- Muscle Strenght Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Venipuncture, Geriatric
Impact of VeinViewer® Vision to Guide Peripheral Venipuncture in Geriatrics
Peripheral venipuncture is a common procedure in geriatrics. This procedure due to altered cutaneous alteration and venous capital associated with age poses problems of comfort and quality of life of elderly patients…
- Trial name
- VeinGER (NCT03139045)
- Testing
- Venous puncture in elderly patients
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Mild Cognitive Impairment
EVASION: Effect of VisuAl Stimulation on attentION
The main objective is to compare changes in information processing speed after 30 days of intervention in participants with a dysexecutive mild cognitive impairment (MCI) and receiving either cognitive stimulation by adapted…
- Trial name
- EVASION (NCT05791994)
- Testing
- Visual cognitive stimulation exercises, Broadcast of a television program
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers