Clinical trials: Gestational Diabetes Mellitus
Breast Density, Body Composition
Chilean Maternal & Infant Cohort Study II (CHiMINCs-II)
The Chilean Maternal \& Infant Cohort Study II (ChiMINCs II) is an ongoing cohort that is part of the Chilean Maternal and Infant Nutrition Observatory of the South-East area of Santiago, Chile.
- Conditions
- Breast Density, Body Composition, Nutritional Status, Mental Health Issue
- Trial name
- CHiMINCs-II (NCT03920098)
- Testing
- Nutrition and mental health during pregnancy
- Where
- Chile
- Volunteers
- 1,927 people, healthy volunteers welcome
- Sponsor
- Instituto de Nutrición y Tecnología de los Alimentos
Polycystic Ovary Syndrome, Gestational Diabetes Mellitus
Screening for GDM in Women With PCOS and Controls
Women with polycystic ovary syndrome (PCOS) are often insulin resistant. During pregnancy, insulin sensitivity decreases. The investigators examine glucose metabolism during oral glucose tolerance test and the incidense of…
- Trial name
- NCT02183558
- Testing
- OGTT by randomization, OGTT by indication
- Where
- Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Large-for-gestational-age Neonates, Glycemic Variability
Diabetes Type One in Pregnancy and Continuos Glucose Monitoring
Type I diabetes mellitus (T1DM) affects about 0.1-0.2% of all pregnancies. T1DM in pregnancy increases the risk of maternal and neonatal complications.
- Conditions
- Large-for-gestational-age Neonates, Glycemic Variability, Hypoglycemia, Pregnancy Outcomes
- Trial name
- DIP1/CRO (NCT04997460)
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Clinical Hospital Centre Zagreb
Diabetes, Gestational, Pre-eclampsia
Usability Evaluation of Gen AI-based Nutrition Chatbot for Pregnant Women
Background: Pregnancy imposes significant physical demands, with complications like gestational diabetes (GDM) and pre-eclampsia posing serious risks.
- Conditions
- Diabetes, Gestational, Pre-eclampsia, AI Chatbot for Prenatal Nutrition Guidance
- Trial name
- NCT07458997
- Testing
- a culturally tailored nutrition AI chatbot for pregnant women
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Hong Kong Metropolitan University
Gestational Diabetes
Low Carb vs Normal Carb in Pregnancy
The overall purpose of this intervention study is to examine whether low-carbohydrate dietary intervention will prevent the development of gestational diabetes mellitus (GDM) in high-risk pregnant women.
- Trial name
- NCT03749889
- Testing
- 100 g carbs, MyPlate
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Hypo- and Hyperglycemia Following Bariatric Surgery, Association Between Glucose Excursions, Fetal Growth and Neonatal Body Composition
The BAMBI II Study
Background Bariatric surgery (BS) is an efficient treatment of severe obesity and diseases like female infertility. Almost half of the population having BS are women of reproductive age, and BMI above 35 kg/m2 and infertility…
- Trial name
- NCT07578597
- Testing
- CGM, Activity tracker, Blood samples
- Where
- Denmark
- Volunteers
- 225 people
- Sponsor
- Odense University Hospital
Child Development, Mother-Infant Interaction
Clinical Interventions to Mitigate Neurodevelopmental Risk
Family Nurture Intervention (FNI) has been shown to facilitate emotional connection and long-term child developmental progress in the NICU population.
- Conditions
- Child Development, Mother-Infant Interaction, Diabetes Mellitus, Gestational
- Trial name
- NCT04233489
- Testing
- Family Nurture Intervention (FNI)
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Columbia University
Gestational Diabetes
EMERGE Mothers and Kids
The EMERGE Mothers and Kids study is a follow-up to the EMERGE trial of women with GDM (N=535) that aimed to determine the effect of the addition of metformin compared to placebo on insulin initiation rates, maternal weight gain…
- Trial name
- NCT06327191
- Testing
- No intervention as the study is observational.
- Where
- Ireland
- Volunteers
- 370 people
- Sponsor
- National University of Ireland, Galway, Ireland
Gestational Diabetes
Prevention of Gestational Diabetes Through Lifestyle Modification
OVERALL OBJECTIVES: 1. To assess the efficacy of a diet and exercise intervention before and/or during pregnancy in the prevention of GDM and its fetal complications in women with high diabetes risk. 2.
- Trial name
- RADIEL (NCT01698385)
- Testing
- Diet and exercise counseling
- Where
- Finland
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Gestational Diabetes
EARLY Pregnancy GLucose prOfiles in Women With and Without GDM Risk Factors: EARLY-GLOW
Background: Gestational diabetes mellitus (GDM) is associated with increased maternal and neonatal complications, including macrosomia, preeclampsia, and long-term metabolic consequences for both mother and child.
- Trial name
- EARLY-GLOW (NCT07783178)
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- DCB Research AG
Gestational Diabetes, Weight Gain During Pregnancy
The IBEP Study: an Intervention for Lifestyle Modification in Women With Gestational Diabetes
The IBEP study is a randomized control trial of a healthy lifestyle intervention program for women with gestational diabetes. The primary aim of the study is to evaluate whether women with gestational diabetes enrolled in an…
- Conditions
- Gestational Diabetes, Weight Gain During Pregnancy, Weight Loss After Pregnancy
- Trial name
- IBEP (NCT01858233)
- Testing
- Intensive Behavioral Modification
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Pennsylvania
Gestational Diabetes
Utility of Real Time Continuous Glucose Monitoring in the Care of Gestational Diabetes Versus Standard Care in Pregnancy Outcomes
Once a pregnant mother is diagnosed with gestational diabetes mellitus (GDM), she will be treated with either diet, medication (i.e., insulin), or both.
- Trial name
- DiP GlucoMo (NCT05037526)
- Testing
- Dexcom G System, Self monitoring blood glucose
- Where
- Switzerland
- Volunteers
- 302 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypertensive Disorder of Pregnancy, Preeclampsia
MumCare: Mum's Cardiovascular Health for Life
The goal of this randomized clinical trial study is to test the potential benefits of eHealth-assisted follow-up after pregnancy complications that confer and increased risk for premature cardiovascular (CV) disease.
- Conditions
- Hypertensive Disorder of Pregnancy, Preeclampsia, Gestational Hypertension, Gestational Diabetes
- Trial name
- MumCare (NCT05835596)
- Testing
- Access to MumCare app
- Where
- Norway
- Volunteers
- 400 people
- Sponsor
- Oslo University Hospital
Gestational Diabetes Mellitus (GDM), Obstetric Anesthesia
ULTRASOUND ASSESSMENT OF GASTRİC VOLUME IN PREGNANT WOMEN UNDERGOİNG ELECTİVE CESAREAN SECTİON, WITH AND WITHOUT GESTATİONAL DIABETES MELLITUS
THE PRIMARY OBJECTIVE OF THIS STUDY IS TO COMPARE GASTRIC VOLUME PRIOR TO ELECTIVE CESAREAN SECTION BETWEEN PREGNANT WOMEN DIAGNOSED WITH GESTATIONAL DIABETES MELLITUS (GDM) AND THOSE WITHOUT GDM.
- Trial name
- GDM (NCT07816705)
- Testing
- GASTRIC ULTRASONOGRAPHY
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Gestational Diabetes
An RCT to Evaluate Incidence, Cost and Clinical Outcomes Using 75 vs 100g. Screening Methods for Gestational Diabetes
Diabetes in pregnancy or gestational diabetes (GDM) is a condition that, if left untreated, may lead to complications for the mother and her baby. It is still not known which is the best method to diagnosis GDM.
- Trial name
- NCT00295659
- Where
- Canada
- Volunteers
- 5,800 people, healthy volunteers welcome
- Sponsor
- Canadian Diabetes Association
Prediabetes, Gestational Diabetes Mellitus
Assessing the Effectiveness of a Weight Watchers-based Lifestyle Intervention for the Primary Prevention of Type 2 Diabetes
This study is a randomized pilot study to assess the applicability of the Weight Watchers model for lifestyle modification to the primary prevention of type 2 diabetes.
- Conditions
- Prediabetes, Gestational Diabetes Mellitus, Obesity
- Trial name
- NCT02000024
- Testing
- Weight Watchers, National Diabetes Education Program
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Indiana University
Gestational Diabetes Mellitus (GDM)
A Risk Score for Prediction of Gestational Diabetesmellitus in China Using Routinely Collected Hospital Data
This project will recruit 6,608 pregnant women in the early stage of pregnancy in Beijing and across the country. Researchers (prenatal examination doctors) will collect the basic information of pregnant women and the results of…
- Trial name
- NCT07160920
- Testing
- Collect clinical data of pregnant women
- Where
- China
- Volunteers
- 6,608 people
- Sponsor
- Peking Union Medical College Hospital
Gestational Diabetes Mellitus (GDM), Microbiome, Human
A Probiotic Based Intervention in Pregnancies Complicated by GDM
This study is a single center randomized control trial of a probiotic based intervention in pregnancies complicated by gestational diabetes.
- Trial name
- ProbioGDM (NCT06794723)
- Testing
- 5-strain probiotic plus prebiotic natural health product
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- Queen's University
Non Insulin Dependent Diabetes, Pregnancy
Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes
Many women come into pregnancy with diabetes that is controlled with either Metformin or diet control; however, the current standard of care for the treatment of preexisting diabetes in pregnancy is insulin.
- Trial name
- MIPOD (NCT00835861)
- Testing
- Metformin, Insulin
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of North Carolina, Chapel Hill
Gestational Diabetes
Glyburide vs Glucovance in the Treatment of GDM
A randomized comparison of glyburide to glucovance (metformin -glyburide) in the management of diabetes in pregnancy.
- Trial name
- GGIG (NCT02726490)
- Testing
- Glyburide, Glucovance
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso