Clinical trials: Gingiva Atrophy
Gingival Recession, Generalized
Xenogenic Collagen Matrix for the Treatment of Multiple Gingival Recessions
The primary aim of this study is to evaluate whether the use of a xenogenic collagen matrix (XCM) for the treatment of multiple adjacent gingival recessions (MAGRs) with a multiple coronally advanced flap technique (mCAF)…
- Trial name
- NCT05693753
- Testing
- Use of XCM for the treatment of MAGRs with mCAF technique, Treatment of MAGRs with CTG
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Cross-linked Hyaluronic Acid
Treatment of Buccal Ginvigal Recessions With the Tunnel Technique in Conjunction With Cross-linked Hyaluronic Acid and Subepithelial Connective Tissue Graft. A Randomized Clinical Trial
To evaluate the outcomes of buccal gengival recession type 1 (RT1) treated with the tunnel technique in conjunction with a cross-linked hyaluronic acid and subepithelial palatal connective tissue grafts.
- Trial name
- NCT05436002
- Testing
- With Cross-linked Hyaluronic Acid
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Gingival Recession
Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment
The aim of the trial is to evaluate the effectiveness of coronally advanced flap (CAF)+connective tissue graft(CTG)+platelet-rich fibrin(PRF) combination in Miller I and II recession treatment by comparing with CAF+CTG.
- Trial name
- NCT02397122
- Testing
- platelet-rich fibrin, connective tissue graft, coronally advanced flap
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Gingival Recession
Root Coverage Comparing an Allograft to a Bovine Xenograft
Root coverage with acellular dermal matrix using the coronally positioned tunnel technique comparing two different donor materials
- Trial name
- NCT02810067
- Testing
- Tunnel + AlloDerm, Tunnel + Novomatrix
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Gingival Recession, Platelet Derived Growth Factor
Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix
The present randomized clinical trial is aimed at evaluating the efficacy of recombinant human platelet-derived growth factor in combination with collagen matrix for the treatment of multiple adjacent gingival recessions
- Trial name
- NCT04462237
- Testing
- Root coverage procedures
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gingival Recession
Xenogeneic Collagen Matrix or Palatal Connective Tissue Graft With a Coronally Advanced Flap in Class III Recessions
The purpose of this multi-center study is to compare the effectiveness of Mucograft versus connective tissue graft in combination with coronal advanced flap for the treatment of Miller class III recessions The connective tissue…
- Trial name
- NCT03344315
- Testing
- experimental: collagen matrix, Active Comparator: autologous connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Gingival Recession
Effect of Orthodontic Treatment on the Stability of Pre-Orthodontic Recession Coverage
This study attempts to assess the effect of orthodontic treatment on the stability of pre-orthodontic recession coverage by connective tissue graft- a randomized controlled clinical trial and thus facilitate better evidence based…
- Trial name
- NCT03886051
- Testing
- Connective Tissue Graft before Orthodontic treatment, Orthodontic treatment only
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession, Plastic Surgery, Platelet
Gingival Recessions Treated by CAF with or Without PRF
The objective of this study was to compare the efficacy of Coronal Advanced Flap (CAF) alone versus CAF combined with Leukocyte-Platelet-Rich Fibrin (L-PRF) to achieve root coverage in patients with gingival recession.
- Trial name
- GR with PRF (NCT06591156)
- Testing
- Root coverage, control group
- Where
- Portugal
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidade Salgado de Oliveira
Gingival Recession, Tooth Abrasion
Treatment of Gingival Recession-type Defects Using Different Restorative Materials
Background: The aim of this study was to evaluate the treatment of multiple gingival recessions associated with non-carious cervical lesions (NCCL) using a modified coronally advanced flap in combination with a sub-epithelial…
- Trial name
- NCT02788266
- Testing
- connective tissue graft+composite resin, connective tissue graft+ glass ionomer, connective tissue graft+giomer
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Gazi University
Recession, Gingival
Influence of Connective Tissue Graft Around Implants
The objective of this randomized controlled clinical study was to evaluate the increase in the volume of peri-implant gingival tissue in implants installed in the aesthetic areas with the use of subepithelial-conjunctive tissue…
- Trial name
- NCT03106506
- Testing
- Connective tissue graft
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Dentin Hypersensitivity
Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity
The world lacks a gold standard treatment for treating dentin hypersensitivity. Fluoride varnish is most commonly used as a treatment but it causes temporary discoloration of tooth structure and may cause irritation or burning of…
- Trial name
- NCT04225247
- Testing
- Single Bond Universal, Bifluorid 12, Xeno V+
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Gingival Recession
MCAT Versus VISTA With Volume Stable Collagen Matrix in RT3 Gingival Recession
This study aims to compare MCAT technique (supraperiosteal approach with coronal advancement of flap) with VISTA technique(subperiosteal approach with coronal advancement of flap), Further, it may be hypothesized that…
- Trial name
- NCT06433986
- Testing
- Modified Coronally Advanced Tunnel (MCAT)Technique, Vestibular Incision Subperiosteal Tunnel Access (VISTA)Technique
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession
Low-intensity Laser Therapy in the Treatment of Gingival Recession
The purpose of this study was to evaluate the 6-month outcomes of applying low-intensity laser therapy associated with connective tissue grafts to treat gingival recession.
- Trial name
- LILT (NCT02118155)
- Testing
- Connective tissue graft
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Gingival Recession
Treatment of Miller Class I and II Gingival Recession Using Non- Pedicled Buccal Fat Pad Graft as Compared to Subepithelial Connective Tissue Graft
This randomized controlled single blinded parallel clinical trial is held to monitor if the use of the non pedicled buccal fat pad graft will result in post operative pain as a primary outcome compared to that occurs with the use…
- Trial name
- NCT03543163
- Testing
- Non- Pedicled Buccal Fat Pad with Coronally Advanced flap, sub-epithelial connective tissue graft
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wound Heal, Platelets; Defect
Effects of Platelet Concentrates on Palatal Wound Healing
Platelet concentrates used in palatal wound healing have been reported to accelerate wound healing and reduce postoperative patient discomfort.
- Conditions
- Wound Heal, Platelets; Defect, Periodontal Inflammation, Gingival Recession
- Trial name
- NCT04097509
- Testing
- AFG application on palatinal wound healing, i-PRF application on palatinal wound healing, control
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingival Recession
PRF for Treating Maxillary Gingival Recession
This is a split-mouth, randomized, controlled clinical trial that aims to evaluate the clinical efficacy of platelet-rich fibrin (PRF) membranes in conjunction with coronally advanced flap (CAF) in treating maxillary gingival…
- Trial name
- NCT05267015
- Testing
- Gingival coverage using coronally advanced flap and a connective tissue graft, Gingival coverage using coronally advanced flap and platelet rich fibrin membranes
- Where
- Palestinian Territories
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Arab American University (Palestine)
Gingival Recession
MINST Versus Conventional Subgingival Instrumentation In RT1 Gingival Recession
Gingival recession is a common condition and its extent and prevalence increase with age. Majority of patients probably present with localized and shallow gingival recession that need a specific treatment because they are…
- Trial name
- NCT06044727
- Testing
- Minimally invasive non surgical periodontal therapy, Conventional subgingival instrumentation
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession
Soft Tissue Augmentation Using Deepithelialized Free Gingival Graft Compared to Connective Tissue Graft in Management of Miller Class I and II Gingival Recession.
The aim of this study will be to clinically assess the soft tissue augmentation achieved by the de-epithelialized free gingival graft with coronally advanced flap versus the subepithelial connective tissue graft with coronally…
- Trial name
- NCT03213483
- Testing
- Coronally advanced flap and subepithelial connective tissue graft, Coronally advanced flap and deepithelialized free gingival graft
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Generalized
Electrical Stimulation Effect on Coronally Advanced Flap
The objective of this study is to evaluate clinically and through the concentration of inflammatory markers, the results of 6 months of electrical stimulation associated with coronally advanced flap for treatment of gingival…
- Trial name
- NCT02987231
- Testing
- CAF, ES
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession
Comparison of Root Coverage Outcomes by NORD Flap Versus Subepithelial Connective Tissue Graft in RT1 Gingival Recession
Management of GR in the initial stages (when there is no inter proximal attachment and bone loss involved) has better clinical outcomes and reduces the chances of further progression of recession.
- Trial name
- Recession type (NCT05844254)
- Testing
- novel overlapping rotated double (NORD) flap
- Where
- India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak