Clinical trials: Gingiva Atrophy
Peri-Implantitis, Peri-implant Mucositis
Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health
Cross-sectional study involving the measurement of the width of lingual keratinized tissue (in the implant locations) in fully edentulous patients restored with dental implants.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Recession, Gingival
- Trial name
- NCT06166017
- Testing
- Exposure to minimal amount of lingual keratinized tissue width
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- George Eastman Dental Hospital, Italy
Gingival Recession, Tooth Abrasion
Mucoderm® Versus CTG in the Treatment of Multiple Gingival Recessions Associated With Non-carious Cervical Lesion.
The aim of the present study is to compare two different multidisciplinary protocols using two types of grafts, porcine acellular dermal matrix (Mucoderm®) versus connective tissue graft, both associated with modified coronally…
- Trial name
- NCT03594513
- Testing
- MCAF, PR, CTG
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession, Localized
Effect of Botulinum Toxin-A on Free Gingival Graft
The aim of this study was to examine the effects of Botulinum Toxin-A (BTX-A) injection to the mental muscle on the free gingival graft (FGG) operation.
- Trial name
- NCT05822323
- Testing
- BTX-A, free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kevser Sokmen
Periodontitis, Periodontal Diseases
Characterization of JAK1 and JAK2 Activation in Gingival Tissues During Homeostasis and Periodontitis
The goal of this observational study is to examine JAK1/2 pathway activation in gingival tissues from adults with healthy gingiva and those with inflamed gingiva (periodontitis).
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Inflammation, Gingival Diseases
- Trial name
- NCT07536204
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chile
Gingival Recession
Vestibular Incision Subperiosteal Tunnel Access With Fascia Lata Allograft in The Treatment of Gingival Recession
The present study will be conducted as a randomized controlled clinical study to assess to evaluate the effect of minimally invasive VISTA with fascia lata allograft in the treatment of gingival recession
- Trial name
- NCT07467096
- Testing
- Vestibular incision sub-periosteal tunnel access + fascia lata, Vestibular incision sub-periosteal tunnel access + subepithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Hams Hamed Abdelrahman
Gingival Recession
Taking Measurements of a Gum Graft Site as it Heals
This is an observational study. The participants in this study will be patients at the Graduate Periodontics Clinic at The Ohio State University who are planning to get a gingival graft to treat their gum recession.
- Trial name
- NCT07386457
- Testing
- Gingival graft surgery to treat gingival recession
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ohio State University
Graft Pain, Gingival Recession
MEBO Ointment and Hyaluronic Acid Gel in the Management of Pain After Free Gingival Graft Harvesting
Postoperative pain as well as bleeding are the most common complications after palatal graft harvesting also postsurgical swelling have been reported , Although different agents were used to protect the denuded areas on the…
- Trial name
- NCT03728244
- Testing
- MEBO ointment, Hyaluronic Acid gel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Changes of Soft Tissue Grafting: A Randomized Study
To correct gum recession, patient's own tissue from the roof of the mouth is harvested and placed where there is root exposed. This is considered gold standard of treatment.
- Trial name
- NCT05633511
- Testing
- Split Mouth Design
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Tufts University
Gingival Recession, Generalized
Ultrasonographic Vascular Supply
Pre-operative ultrasound enables visualization of mandibular arterial branches relevant to flap design in mucogingival surgery. This study documents the pre-and post operative course of these arteries in four CAF procedures using…
- Trial name
- NCT07727707
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Periodontal Attachment Loss
ESWT on Human Gingival Fibroblasts
The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy (ESWT) has recently become popular.
- Trial name
- ESWT (NCT05766293)
- Testing
- extracorporeal shockwave device, Fibroblast cell lines not subjected to shockwaves from extracorporeal shockwave device
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Dr Prabhuji MLV
Tooth Loss, Recession, Gingival
Soft Tissue Volume Gain and Stability Comparing Palate and Tuberosity
The goal of this study is to compare clinical and histologically the soft tissue changes in terms of volume gain and stability around dental implants in cases where a subepithelial connective tissue graft from the palate or from…
- Trial name
- NCT03090906
- Testing
- Soft tissue augmentation palate, Soft tissue augmentation tuberosity, Intraoral optical scan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Gingival Recession, Localized, Gingival Recession, Generalized
Pain Management After Free Gingival Graft Surgery
Keratinized gingiva reduces the risk of gingival disease and infection by protecting the tissue around the teeth and is therefore very important for gingival health.
- Conditions
- Gingival Recession, Localized, Gingival Recession, Generalized, Gingival Recession, Mucogingival Surgery
- Trial name
- NCT06675734
- Testing
- diclofenac sodium solution
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Aydın University
Gingival Recession, Gingival Diseases
Influence of Anatomical Factors Upon Root Coverage
Introduction: Gingival recession is a lesion characterized by the loss of attachment of root surface of the tooth, resulting in an apical migration of the gingival margin that occasionally generates aesthetic problems…
- Conditions
- Gingival Recession, Gingival Diseases, Periodontal Attachment Loss
- Trial name
- NCT04813302
- Testing
- Coronally advanced flap and connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Hyaluronic Acid, Open Flap Debridement
Adjunctive 0.8% Hyaluronic Acid Gel in Open-Flap Surgery for Thin Gingival Phenotype in Patients With Periodontitis
The aim of this study is to evaluate the clinical effectiveness of 0.8% hyaluronic acid (HA) gel as an adjunct to open flap debridement (OFD) in periodontitis patients with a thin gingival phenotype.
- Conditions
- Hyaluronic Acid, Open Flap Debridement, Periodontitis, Gingival Phenotype
- Trial name
- NCT07130266
- Testing
- Procedure/Surgery: Hyaluronic acid gel application, giving an impression of the application
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Bezmialem Vakif University
Gingival Recession, Lack of Keratinized Gingiva
The Effect of Free Gingival Graft on Root Closure
Free gingival graft is a mucogingival surgical technique applied to increase keratinized gingival width and reduce gingival recession.
- Trial name
- NCT05604391
- Testing
- Free gingival graft placed apically, Free gingival graft placed coronally
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Gingival Recession
Evaluation of Two Types of Matrix (Mucograft® and Mucoderm®) Associated With Coronally Advanced Flap
The aim of this study is to evaluate clinically the results of two types of matrix (Geistlich Mucograft® and Mucoderm®) associated with CAF technique for the treatment of gingival recessions.
- Trial name
- NCT03667105
- Testing
- CAF, MC, XDM
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession
Gingival Recession and Oral Health-related Quality of Life: A Cross-sectional Study
Aim of this study is the assessment of gingival recession and its impact on oral health related quality of life in tertiary health care center in Haryana state. Objectives: 1.
- Trial name
- NCT07557277
- Testing
- Systemically healthy individuals 18-45 years of age, having gingival recession
- Where
- India
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession
Non-Pedicled Buccal Fat Pad Graft in the Treatment of Gingival Recessions
Background: This randomized controlled clinical study of split-mouth aimed to compare non-pedicled buccal fat pad graft (BFPG) with subepithelial connective tissue graft (SCTG) in the treatment of Miller Class I or II gingival…
- Trial name
- NCT02393053
- Testing
- Treatment with subepithelial connective tissue graft (SCTG), Treatment with non-pedicled buccal fat pad graft (BFPG)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Positivo
Periodontal Inflammation, Alveolar Bone Loss
The Effect of Non-surgical Periodontal Treatment on Dickkoff-1 and Secreted Frizzled Related Protein-5 Levels
Periodontitis is a condition that is defined by microbial-associated, host-induced inflammation, which ultimately results in the loss of periodontal attachment.Periodontal clinical parameters are the most reliable indicators of…
- Conditions
- Periodontal Inflammation, Alveolar Bone Loss, Periodontal Diseases
- Trial name
- NCT06727929
- Testing
- Collection of gingival crevicular fluid, ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Recession, Gingival
Root Coverage With Acellular Dermal Matrix and Bovine Derived Osseous
The study will consist of a randomized controlled clinical study trial comparing the results of coronally positioned flap with AlloDerm GBR plus bovine derived xenograft versus coronally positioned tunnel with AlloDerm GBR plus…
- Trial name
- NCT03582995
- Testing
- Flap Surgery for root coverage with Alloderm and xenograft, Tunnel Surgery for root coverage with Alloderm and xenograft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Louisville