Clinical trials: Gingiva Atrophy
Gingival Recession
Volume-Stable Collagen Matrix Versus Subepithelial Connective Tissue Graft for Multiple Gingival Recessions
Gingival recession is a clinical condition in which the gingival margin is displaced apically, exposing the root surface. This condition may be associated with esthetic concerns, dentin hypersensitivity, and difficulties in oral…
- Trial name
- VCMX-SCTG (NCT07613775)
- Testing
- Volume-stable xenogeneic collagen matrix (VCMX), Subepithelial connective tissue graft (SCTG)
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Non Carious Cervical Lesion, Gingival Recessions
Association Between Periodontal Morphology and Non-Carious Cervical Lesions
This observational study aims to investigate the relationship between periodontal morphology, oral hygiene habits, and non-carious cervical lesions (NCCLs) in adults aged 18-65 years.
- Trial name
- NCCL-PM (NCT07629492)
- Testing
- Periodontal Examination and Oral Habit Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Wounds and Injuries, Transplants
Free Gingival Graft Adjunct With Low Level Laser Therapy
The present placebo-controlled parallel design clinical study was planned to determine the effect of low level laser therapy on clinical periodontal conditions and dimensions of free gingival graft as well as postoperative pain…
- Conditions
- Wounds and Injuries, Transplants, Gingival Recession, Localized, Low-Level Light Therapy
- Trial name
- NCT03425695
- Testing
- CheseeTM Diode Laser, Clinical examination
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingival Recession
The Influence of Non-Carious Cervical Lesions on Root Coverage
The goal of this prospective cohort study is to evaluate the effect of non-carious cervical lesions (NCCLs) on the outcome of root coverage therapy.
- Trial name
- NCT06438094
- Testing
- Root coverage surgery by means of a coronally advanced flap combined with a connective tissue graft, Reconstruction of the CEJ with a composite restoration followed by root coverage surgery by means of a coronally advanced flap combined with a connective tissue graft
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gonzalo Blasi
Gingival Recession, Palate; Wound
To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting
This randomized clinical comparative study will evaluate the postoperative pain following the FGG graft harvest procedure technique covered by four different methods for coverage of the palatal donor site.
- Trial name
- NCT03895476
- Testing
- palatal wound will be cover with collagen and sutures, palatal wound covered with platelet rich fibrin, palatal wound covered with a collagen sponge and cyanoacrylate
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gingival Recession
Platelet Rich Fibrin in the Treatment of Full Thickness Palatal Wounds
In this study it will be investigated the usefulness of Platelet-Rich Fibrin (PRF) on in the full thickness palatal graft donor site healing acceleration and in the patient's morbidity reduction.
- Trial name
- NCT04043039
- Testing
- Palatal wound bandage with PRF, Palatal wound bandage with Gelatine Sponge
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Gingival Recession, Mucogingival Surgery
V-Reverse Suture Technique Compared to Traditional Anchored Sling Suture in Treating Multiple Gingival Recession
The goal of this split-mouth pilot study is to study the effect of two different suturing techniques in root coverage using coronally advanced flap tunnel in multiple adjacent recession cases to see which technique will give…
- Trial name
- NCT07602829
- Testing
- coronally advanced tunnel with v-reverse suture, coronally advanced tunnel with anchored sling suture
- Where
- Jordan
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Recession, Gingival
Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative
24 patients will be treated with a coronally positioned tunnel with AlloDerm RTM with or without the addition of Enamel Matrix Derivative to compare the baseline and 6-month changes in recession defect coverage, clinical…
- Trial name
- NCT05565079
- Testing
- Regenerative tissue matrix and enamel matrix derivative, Regenerative tissue matrix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Gingival Recession
Dimensional Changes: Randomized Clinical Trial
The goal of this clinical trial is to evaluate the dimensional changes in the short and long-term in patients with thin gum tissues who have gum grafts placed on either denuded bone or gum grafts placed on a bone with some…
- Trial name
- NCT05684068
- Testing
- Gum Graft Placed on Denuded Bone, Gum Graft Placed on Split Thickness Periosteal Bed Preparation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Gingival Recession
Treatment of Local Gingival Recession With an Enamel Matrix Protein Coated Collagen Matrix
The clinical trial studies patients with gingival recession defects (receding gums). The goal of the study is to test whether the additional use of enamel matrix derivatives (EMD), combined with the use of a coronally advance…
- Trial name
- EmdoDerm (NCT05799859)
- Testing
- Use of coronally advanced flap (CAF) and collagen matrix (CM), Use of coronally advanced flap (CAF) and collagen matrix (CM) and additional application of enamel matrix derivatives (EMD).
- Volunteers
- 15 people
- Sponsor
- Medical University of Graz
Gingival Recession, Localized
Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects
The goal of this randomized clinical study is to assess the root coverage outcomes and patient morbidity following the treatment of single maxillary recession-type defects using a coronally advanced flap (CAF) combined with a…
- Trial name
- NCT06404762
- Testing
- tSCTG+ CAF, pSCTG+ CAF
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession, Localized
Effect of Restoration Margin Level in the Treatment of Gingival Recession Associated With Non-carious Cervical Lesion
The aim of this randomized, parallel-group clinical trial was to compare the 1-year periodontal, root coverage, esthetic, and patient-centered outcomes of the partial restoration placement with different apical margin levels…
- Trial name
- NCT05682274
- Testing
- Partial restoration approach combined with CAF+CTG
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession, Mucogingival Surgery
Role of Manuka Honey in Lowering Pain and Boosting Healing After Gum Graft Surgery.
The goal of this clinical trial is to learn if medical grade Manuka Honey works to lower pain and improve healing sites after gum grafting surgery.
- Trial name
- NCT07016373
- Testing
- Palatal Plate without Manuka Honey, Palatal plate with Manuka Honey
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Nancy Mouradian
Gingival Recession, Localized, Gingival Recession
Root Coverage With Tunneling Technique With Connective Tissue Versus Coronal Advancement Flap Technique.
This is a randomized triple-blind clinical trial. This comparative clinical study investigates the efficacy of root coverage using two periodontal techniques: the tunneling technique and the coronal advancement technique.
- Trial name
- NCT06228534
- Testing
- Root coverage with tunneling technique
- Where
- Ecuador
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Luis Alberto Chauca Bajaña
Gingival Recession
Areal and Linear Comparison of Gingival Recession
Recent advances in digital technology have led to the emergence of precise methods for measuring gingival recession and tissue thickness.
- Trial name
- agr (NCT06502782)
- Testing
- digital assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Tooth Sensitivity, Gingival Recession Generalized Moderate
Biomimetic Hydroxyapatite Toothpaste and Mouthwash for Reducing Dental Sensitivity
This randomized controlled clinical trial evaluates the effectiveness of a biomimetic hydroxyapatite-based toothpaste and mouthwash in reducing dental sensitivity in patients with gingival recession.
- Conditions
- Tooth Sensitivity, Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate
- Trial name
- SENS-BIOREP (NCT07057141)
- Testing
- Biorepair Total Protection Toothpaste, Biorepair High-Density Mouthwash
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Pavia
Gingival Recession
Using Inverted Periosteal Pedicle Flap in Treatment of Gingival Recession
Perioteum in the recession defect site will be used as an autogenous graft after raising a flap and the results will be compared with another group which will be treated by the gold standard ( coronally advanced flap with…
- Trial name
- IPPF (NCT03701191)
- Testing
- Inverted periosteal pedicle flap
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Marwa El Sayed Abbas Ahmed
Gingival Recession, Recession, Gingival
Coronally Advanced Flap With Alloderm Versus Coronally Advanced Flap With Micro-needling on RT1 Gingival Recession
This study aims to assess the effect of micro-needling together with coronally advanced flap procedure on the gain of gingival thickness (GT) and keratinized tissue width (KTW) and compare it to Alloderm with coronally advanced…
- Conditions
- Gingival Recession, Recession, Gingival, Thin-gingiva
- Trial name
- NCT05470660
- Testing
- Root coverage using coronally advanced flap combined with micro-needling, coronally advanced flap combined with Alloderm
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Comparison of Cyanoacrylate Tissue Adhesive With Suture in the Treatment of Gingival Recession
The aim of this randomized controlled clinical study was to determine the effects of gingival recession closure procedures performed with tissue adhesive and suture on gingival thickness, To evaluate the effect on the amount of…
- Trial name
- NCT06499155
- Testing
- Use of periacryl in gingival recession closure procedures, Use of sutures in gingival recession closure procedures
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Root Coverage
The Evaluation Clinical Results of Coronally Advanced Flap With Platelet Rich Fibrin
The aim of this study was to evaluate the clinical outcomes of platelet- rich fibrin and coronally advanced flap technique in the treatment of multiple gingival recessions in comparison with connective tissue graft technique.
- Trial name
- NCT04942821
- Testing
- Platelet rich fibrin and coronally advanced flap, Connective tissue graft and coronally advanced flap
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Marmara University