Clinical trials: Gingiva Atrophy
Gingival Recession
Root Coverage in Miller Class III Recessions by Perio-ortho Treatment
To predict root coverage in Miller class III gingival recessions in chronic periodontitis patients using interdisciplinary orthodontic-periodontal surgical treatment as compared to periodontal surgical treatment alone.
- Trial name
- NCT04255914
- Testing
- Periodontal plastic surgery procedure and orthodontic treatment, Periodontal plastic surgery procedure
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession (Miller II)
Evaluation of The Effect of Injectable Platelet-rich Fibrin With Collagen Membrane in Miller Class II Gingival Recession Coverage
This study aims to evaluate the effect of injectable Platelet-Rich Fibrin (i-PRF) in combination with collagen membrane in the treatment of Miller Class II gingival recession.
- Trial name
- NCT07717398
- Testing
- Group (1), Group 2
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Thin-gingiva, Mucogingival Deformity on Edentulous Ridge
Harvest of Free Gingival Grafts With or Without the Application of Hemostatic Sutures
Randomized, single-center trial with 2 parallel arms and a 1:1 allocation ratio, with the aim of comparing clinical and microvascular healing and patients related outcomes, which follow the harvest of a free gingival graft, where…
- Conditions
- Thin-gingiva, Mucogingival Deformity on Edentulous Ridge, Gingival Recession
- Trial name
- NCT05381623
- Testing
- Simplified suture-less approach, Application of hemostatic sponges and compressive sutures
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Universidad Complutense de Madrid
Gingival Recession
Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions
Aim: The aim of this randomized clinical trial is to evaluate the use of the porcine acellular dermal matrix (PADM) for the treatment of RT1 localized gingival recessions.
- Trial name
- NCT06006780
- Testing
- Porcine acellular dermal matrix, Coronally advanced flap (CAF)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Periodontal Bone Loss, Chronic Periodontitis
Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft
The present study aimed to evaluate the effects of enamel matrix derivatives either alone or combined with autogenous bone graft applied to intrabony defects in chronic periodontitis patients on clinical/radiographic parameters…
- Trial name
- NCT02218515
- Testing
- Open Flap Debridement, EmdogainⓇ(Enamel Matrix Derivative), EmdogainⓇEnamel Matrix Derivative+Autogenous Bone
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Haner Direskeneli, Prof
Gingival Recessions
Vestibular Incision Subperiosteal Tunnel Access (VISTA) Technique Versus Coronally Advanced Flap (CAF) Combined With a Connective Tissue Graft for the Treatment of Maxillary Gingival Recessions
Gingival recession (GR) is a common oral health problem that causes sensitivity, esthetic concerns and hygiene problems. Successful root coverage can be achieved by various surgical techniques.
- Trial name
- NCT06755294
- Testing
- Vestibular incision subperiostal tunnel technique, CAF
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Alveolar Bone Loss, Alveolar Ridge Pathology | Gingiva | Dental
Comparative Study of Gene-activated Bone Substitute and Xenogenic Bone Matrix in Alveolar Ridge Augmentation
The study aim is to compare the effectiveness of two bone substitutes, the gene-activated bone substitute based on octacalcium phosphate and plasmid DNA encoding VEGFA gene and xemogenic deproteinized bone matrix, mixed with…
- Trial name
- NCT04511689
- Testing
- gene-activated bone substitute mixed with autobone
- Where
- Russia
- Volunteers
- 24 people
- Sponsor
- Histograft Co., Ltd.
Gingival Recession
Periodontal Phenotype and Laterally Positioned Flap in Isolated Gingival Recession
The aim of this study is to estimate the effect of periodontal phenotype on the outcome of isolated gingival recession by laterally positioned flap.The primary objective of study is to assess the changes in gingival margin in the…
- Trial name
- NCT04255888
- Testing
- Laterally positioned flap in thick periodontal phenotype., Laterally positioned flap in thin periodontal phenotype.
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession, Localized
VCMX, PRF and SCTG Treatment in the Gingival Recessions
Comparison of Volume-Stable Collagen Matrix, Platelet-Rich Fibrin, and Subepithelial Connective Tissue Graft in the Treatment of Multiple Adjacent Gingival Recessions: A Parallel-Group, Randomized, Controlled Clinical Trial
- Trial name
- NCT07345520
- Testing
- Volume-Stable Collagen Matrix
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Gingival Recession
Facial Mucosal Level Determinants for Single Immediately Placed Implants Evaluated by Novel Ultrasonography
A single center, prospective clinical trial is planned to investigate the effect of different emergence angles of implant restorations on peri-implant soft tissue recession and implant marginal bone loss.
- Trial name
- NCT03558282
- Testing
- Recession Observation, Crown Contour Observation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Michigan
Diabetes Mellitus, Gingival Recession, Generalized
Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial
The goal of this clinical trial is to evaluate local and systemic factors involved in palatal mucosal healing after Free Gingival Graft harvest in diabetic patients and to compare them with those in non-diabetic patients.
- Conditions
- Diabetes Mellitus, Gingival Recession, Generalized, Gingival Recession, Localized
- Trial name
- NCT07500935
- Testing
- Free gingival graft
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mauro Santamaria
Gingival Recession, Atrophy
The Effect of Different Gingival Biotypes on Dimensional Stability of Free Gingival Graft
The aim of this study is to compare the effect of mesial and distal adjacent gingival biotypes of the tooth / teeth region of free gingival graft (FGG) on the shrinkage ratio of graft at 6 months postoperatively.
- Trial name
- NCT03616197
- Testing
- free gingival graft
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Gingival Recession
Coronally Advanced Flap With Connective Tissue Graft and PRF for Recession Coverage
Over the years, numerous surgical techniques such as free autografts and pedicle grafts have been introduced to correct gingival recession defects.
- Trial name
- NCT03023995
- Testing
- CAF with Platelet rich fibrin, CAF with connective tissue graft
- Volunteers
- 10 people
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Gingival Recession, Suture
Timing Suture Removal on Root Coverage Procedures
Gingival recession is defined as the displacement of the soft tissue margin apical to the cemento-enamel junction with exposure of the root surface.
- Conditions
- Gingival Recession, Suture, Root Coverage
- Trial name
- NCT04826653
- Testing
- Suture removal
- Where
- 2 sites in Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Gingival Recession, Localized
Theravex Oral and Theravex Tissue Care Plus in the Healing Process of Mucogingival Surgery
This clinical study assesses the efficacy of two novel bioactive solutions, Theravex Oral and Theravex Tissue Care Plus, in enhancing soft tissue healing after periodontal surgery.
- Trial name
- NCT07430670
- Testing
- Modified Free Gingival Graft (M-FGG), Theravex Bioactive Solutions (Tissue Care Plus and Oral)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Gingival Recession, Localized
Gingival Response and Marginal Adaptation of Zirconia Crowns With Two Subgingival Margin Designs
The aim of the study is to evaluate the effect of feather edge finish line and deep chamfer finish line on gingival position, bleeding on probing and marginal adaptation.
- Trial name
- NCT04729569
- Testing
- Feather edge finish line preparation, Deep chamfer finish line preparation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Efficacy of Methods to Treat Multiple Gingival Recession Defects
Rationale: Treatment of gingival recession defects requires coronal advancement of the gingival margin due to patient esthetic demand, tooth sensitivity and improvement of tooth prognosis, which can be accomplished either through…
- Trial name
- NCT03124329
- Testing
- Coronally Advanced Flap, Intrasulcular Tunneling, Vestibular Incision Subperiosteal Tunnel Access (VISTA)
- Where
- United States
- Sponsor
- University of Southern California
Open Wound of Palate Without Complication, Pain, Postoperative
The Effect of Ozone Therapy on Pain Perception After Free Gingival Graft Surgery in Patients With Mucogingival Defects
Gaseous ozone (O3-triatomic oxygen) is the third-strongest oxidizing agent worldwide. It influences the cellular and the humoral immune system, by stimulating the proliferation of immunocompetent cells and the synthesis of…
- Conditions
- Open Wound of Palate Without Complication, Pain, Postoperative, Free Gingival Grafts, Mucogingival Defects
- Trial name
- NCT05291715
- Testing
- Ozone generator device (Ozone DTA-APOZAa-enterprize CO9-Taiwan, R.0.C)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Omaima Mossad Mahmoud AL-Sherbini
Gingival Recession
Patient Satisfaction After Root Coverage Using VISTA Technique Compared to MCAF Technique With PRF.
VISTA technique with PRF compared to MCAF technique with PRF to treat gingival recession
- Trial name
- NCT03328442
- Testing
- VISTA Technique, modified coronally advanced flap
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Hyaluronic Acid With Connective Tissue Grafting for Gingival Recession
This study evaluates whether adding 0.8% hyaluronic acid (HA) to connective tissue grafting and coronally advanced flap surgery improves clinical and esthetic outcomes in the treatment of gingival recession.
- Trial name
- NCT07291583
- Testing
- Hyaluronic Acid (0.8%) - Applied over CTG before flap closure (Test group only)., Connective Tissue Graft + Coronally Advanced Flap (CTG + CAF)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi