Clinical trials: Gingiva Atrophy
Gingival Recession
Treatment of Multiple Gingival Recessions
Gingival recession (GR) is frequently associated with deterioration in dental esthetics and dental hypersensitivity. Outcomes from recent systematic reviews have demonstrated that when the root is covered and the gain in the…
- Trial name
- 3DMUCO (NCT02818855)
- Testing
- Coronally advanced flap (CAF), Collagen Matrix, Subepithelial connective tissue graft
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gingival Recession
Morbidity and Coverage Outcome With Connective Tissue Graft Used With Coronally Advanced Flap and Tunneling Technique
The aim of this randomized-controlled clinical trial is to compare the patient morbidity and root coverage outcomes of a sub-epithelial connective tissue (SeCTG) used in combination with a coronally advanced flap (CAF) and tunnel…
- Trial name
- NCT02269748
- Testing
- Tunnel technique with subepithelial connective tissue, Coronally advanced flap, Analgesic Therapy
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Gingival Recession Localized Moderate, Dental Implant
Free Soft Tissue Grafts FSTG) Using Autograft Palatal Donor Tissue vs. Xenograft Collagen Matrix (Zderm™)
Participant in this study are asked to participate because they have teeth or dental implants that were identified as having very little gum tissue and would benefit from gum tissue graft surgery.
- Trial name
- NCT07713199
- Testing
- Zderm
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Periodontal Diseases
Periodontal Disease Prediction System
The purpose of this study was to develop a periodontal disease prediction software and a patient-based gingival recession simulator for clinical practice aiming at improving oral hygiene motivation of patients with periodontal…
- Trial name
- NCT05809570
- Testing
- Clinical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Gingival Recession, Xenograft Model
Two Different Surgical Techniques for the Treatment of Multiple Gingival Recessions With Porcine Collagen Matrix
The gold standard for gingival recession treatment is the coronal repositioning of the flap associated with the subepithelial connective tissue graft.
- Conditions
- Gingival Recession, Xenograft Model, Gingival Recession, Generalized
- Trial name
- NCT03619096
- Testing
- tunnel technique for Root coverage with Porcine collagen Matrix, extended fla technique for Root coverage with Porcine collagen Matrix
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentinal Hypersensitivity
Comparison Of Clinical Efficacy Of A Herbal And A Non-Herbal Mouthwash On Dentinal Hypersensitivity
Aim of this study was to assess and compare the efficacy of a commercially available novel herbal mouthwash containing potassium nitrate on Dentinal Hypersensitivity (DH) compared to a placebo and non herbal potassium nitrate…
- Trial name
- NCT02008500
- Testing
- Herbal Mouthwash, Non Herbal Mouthwash
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Gingival Recession, Generalized
Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
Subepithelial connective tissue graft (SCTG) is considered the gold standard for root coverage treatment. However, it is associated with postoperative morbidity, limited amount of donor tissue, and longer surgical time.
- Trial name
- NCT03207984
- Testing
- Root coverage surgery
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gingival Recession, Localized
Reconstruction of Deficient Interdental Papilla Using Stem Cells vs Physiological Saline
The goal of this study is to assess the reconstruction of interdental papilla following the injection of UC-MSCs or physiological saline in patients with interdental papilla deficiency.
- Trial name
- NCT06388447
- Testing
- Umbilical cord-mesenchymal stem cells
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Gingival Recession
Platelet Rich Fibrin on Root Coverage of Gingival Recessions
Several surgical techniques and various adjunctive agents have been used to covered Gingival Recession (GR) and promote clinical outcomes.
- Trial name
- NCT04248049
- Testing
- Platelet rich fibrin
- Where
- Colombia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
Gingival Recession
Microsurgical Versus Conventional Semilunar Coronally Advanced Flap
BACKGROUND: The semilunar coronally repositioned flap (SLCRF) has been used for the treatment of recession defects (GR). Recently a microsusgical (MICRO) has been successfully employed with the procedure apparently resulting in…
- Trial name
- NCT02433899
- Testing
- MICROSURGERY, MACROSURGERY, Dexamethasone
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Gingival Recession
CAF With or Without CTG for the Treatment of Single Maxillary Gingival Recession With NCCL
This studies evaluate the efficacy of the coronally advanced flap (CAF) with or without connective tissue graft (CTG) for the treatment of single maxillary recession associated to non carious cervical lesion (NCCL).
- Trial name
- NCT03862534
- Testing
- CAF, CAF + CTG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florence
Mucosal Erosion, Gingival Recession
Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques
This study has been initiated to evaluate the question, "What is the best way to protect the palate after a gum graft is removed?" The overall objective is to determine if there is a difference in PROMs of donor site healing…
- Trial name
- NCT06892496
- Testing
- Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Virginia Commonwealth University
Gingival Recession
Pinhole Versus Tunnel for Soft Tissue Recession
This is an assessor-blinded split-mouth randomized clinical study to compare root coverage and gingival tissue thickness following two different surgical procedures for non-autologous grafting: the pinhole surgical technique…
- Trial name
- NCT04513041
- Testing
- Pinhole surgical technique and tunnel technique in a split mouth design
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mohanad Al-Sabbagh
Gingival Recession
A Clinical Trial Testing Root Coverage With Acellular Dermal Matrix in Thin and Thick Gingival Biotypes
Gingival recession is a common defect among the American population. It is also a major cause for root decay, hypersensitivity, contributes to tooth mobility and low self-esteem.
- Trial name
- NCT03057730
- Testing
- Acellular Dermal Matrix
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tufts University
Gingival Recession
Evaluation of the Treatment of Multiple Gingival Recession Using Modified Coronally Advanced Tunnel With Subepithelial Connective Tissue Graft Depending on the Positioning of the Graft
Microsurgical coronally advanced tunnel procedures using subepithelial connective tissue grafts (sCTG) are predictable for healing of multiple adjacent type 1 and 2 gingival recessions (RT1 and RT2).
- Trial name
- NCT06366022
- Testing
- The tunnel technique for root coverage with CTG with inner side of the graft, The tunnel technique for root coverage with CTG with outer side of the graft
- Where
- Poland
- Volunteers
- 21 people
- Sponsor
- Medical University of Warsaw
Gingival Recession
Assessment of The Accuracy of Complete Crown 3D Superimposition Technique Relative to The Gold Standard Technique for Digital Quantification of Volumetric Soft Tissue Changes in The Esthetic Zone
The aim of this study is to assess the precision of the complete crown technique employed for the superimposition of 3D models, specifically in the quantitative volumetric evaluation of gingival tissues.
- Trial name
- NCT06457672
- Testing
- Group I, Group II
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Gingival Recession, Gingival Abrasion
Evaluation of Gingival Fissures Associated With Soft and Medium Toothbrushes
Gingival fissures (GF) have been suggested as risk indicators for clinical attachment loss (CAL) and gingival recession, especially in free surfaces and in patients with low plaque scores.
- Conditions
- Gingival Recession, Gingival Abrasion, Wounds and Injuries
- Trial name
- NCT03367481
- Testing
- Toothbrush type
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Recession, Gingival
Novel Porcine Dermal Matrix in the Treatment of Multiple Adjacent Gingival Recessions
The aim of this study was to assess the clinical efficacy of the acellular porcine derived collagen matrix (PADM) in comparison with connective tissue graft (SCTG ) in the treatment of multiple adjacent gingival recessions…
- Trial name
- NPDMMAGR (NCT03163654)
- Testing
- Surgery 1, Surgery 2
- Where
- Serbia
- Volunteers
- 16 people
- Sponsor
- Botiss Medical AG
Insufficient Keratinized Tissue, Gingival Recession
Cyanoacrylate Versus Sutures for Free Gingival Graft Stabilization
This randomized controlled clinical trial evaluated the effectiveness of butyl-cyanoacrylate tissue adhesive compared with conventional sutures for stabilization of free gingival grafts.
- Conditions
- Insufficient Keratinized Tissue, Gingival Recession, Mucogingival Defects
- Trial name
- NCT07359300
- Testing
- Free Gingival Graft Stabilization With Butyl-Cyanoacrylate, Free Gingival Graft Stabilization With Sutures
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Gingival Recession Types One(RT1), Gingival Crevicular Fluid
Comparison of Connective Tissue and PRF in Gingival Recession
Aim: In this study, it was aimed to comparatively investigate the clinical and biochemical effects of subepithelial connective tissue graft and coronally advanced flap (SCTG + CAF) or titanium-prepared platelet rich fibrin and…
- Trial name
- NCT07877064
- Testing
- Titanium-prepared Platelet-Rich Fibrin, SCTG + CAF
- Volunteers
- 22 people
- Sponsor
- Ataturk University