Clinical trials: Gingiva Disorder
Gingival Recession
Thick vs. Thin Acellular Dermal Matrix (ADM)
To study and compare a thick vs thin acellular dermal matrix for root coverage using the coronally positioned tunnel technique.
- Trial name
- ADM (NCT03392038)
- Testing
- Thin ADM, Thick ADM
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Gingival Recession
Tunneling Technique in Treatment of Miller's Class III Gingival Recession
Several surgical techniques have been proposed to correct recession defect and attain root coverage. Though, the majority were executed on Miller Class I and II recession defects.
- Trial name
- NCT03657706
- Testing
- group A (Tunnel procedure with subepithelial connective tissue graft (sCTG), group B (Tunnel procedure with modified free gingival graft (mFGG))
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Periodontitis
Clinical Efficacy Of 810 Nanometer Diode Laser As An Adjunct To Mechanical Periodontal Treatment Of Residual Periodontal Pockets
Background: Aim of this randomized controlled parallel-designed study was to evaluate the effects of diode laser as an adjunct to mechanical periodontal treatment on clinical parameters and gingival crevicular fluid (GCF) volume…
- Trial name
- NCT02531555
- Testing
- 810 Nanometer Wavelenght GaAlAs Diode Laser, Gracey curettes
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Marmara University
Paralytic Ileus
The Effects of Gum Chewing on Bowel Function Recovery Following Cesarean Section
Following all abdominal surgery, paralytic ileus commonly develops. Surgeons have traditionally withheld postoperative oral intake until the return of bowel function to prevent related complications.
- Trial name
- GUM01 (NCT01131416)
- Testing
- Gum chewing
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Periodontitis, Gingivitis
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : improved dental health reduced risk of pneumonia better glucose…
- Conditions
- Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections
- Trial name
- NHOralHealth (NCT06890676)
- Testing
- Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Missouri Department of Health and Senior Services
Gingival Recession, Lack of Keratinized Gingiva
A Comparison of Side Access Mucosal Releasing Incision (SAMRI) and Sulcular Tunnel Access to Treat Gingival Recession.
This study will compare two incision designs to allow for coronal gingival/mucosal flap advancement and tissue augmentation with acellular dermal matrix (ADM) graft around teeth with gingival recession and a lack of adequate…
- Trial name
- NCT04179448
- Testing
- SAMRI, STA
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gingivitis, Dental Plaque
"Safeguard Your Smile" an Oral Health Literacy Intervention Promoting Positive Oral Hygiene Self-care Behavior
The purpose of the investigators' study is to assess effectiveness of community based oral health literacy intervention promoting positive oral hygiene self-care behavior among Montreal's Punjabi immigrants.
- Trial name
- NCT02521155
- Testing
- Safeguard Your Smile an oral health literacy intervention
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Gingival Recession
Platelet Rich Fibrin and Autologous Fibrin Glue
Platelet-rich fibrin (PRF) and Autologous Fibrin Glue (AFG) are fibrin preparation derived from human blood samples and are used in regenerative dentistry.
- Trial name
- NCT03734458
- Testing
- Group A - PRF plus AFG with a CAF, Group B - PRF only with a CAF, Group C - CTG with a CAF
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gingivitis
Comparing the Inter-dental Brush to Dental Floss
The study's purpose is to find an easy and effective alternative to dental floss for those persons who cannot or choose not to dental floss so that they can maintain and/or achieve optimal oral health.
- Trial name
- NCT00743548
- Testing
- IB = Interdental brush, the intervention, DF = Dental floss, the positive control
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hyaluronic Acid, Gingival Recession, Localized
Hyaluronic Acid and Free Gingival Graft Healing
This study aims to evaluate the impact of locally applied hyaluronic acid on free gingival graft wound bed healing and palatal donor site wound healing. Forty subjects will be randomly divided in two separate groups.
- Conditions
- Hyaluronic Acid, Gingival Recession, Localized, Pain, Postoperative
- Trial name
- NCT05990049
- Testing
- Hyadent BG
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Gingivitis
Incentives for Daily Tooth Brushing to Reduce Gingivitis
In this randomized controlled study, the investigators compare two classes of behavioral approaches to change habits and health outcomes with an application to dental health: cognitive vs. behavioral financial incentives.
- Trial name
- NCT02160418
- Testing
- Financial Incentives, Cognitive Incentives, Financial and Cognitive Incentives
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Plaque, Gingivitis
Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study
The objective of this randomized, single-center, examiner-blind, controlled, parallel group, six-month clinical study is to compare the antiplaque/antigingivitis potential of a no-alcohol essential oil containing mouthrinse and…
- Conditions
- Plaque, Gingivitis, Gum Inflammation, Bleeding
- Trial name
- NCT02980497
- Testing
- Listerine Zero Mouthwash (without alcohol), Listerine Antiseptic Mouthwash (with alcohol)
- Where
- Brazil
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Dental Plaque, Gingivitis
Essential Oil+ELA, Plaque and Gingivitis
A commercially available mouth rinse with ethyl lauroyl arginate and essential oils claims to have enhanced antimicrobial properties as compared to the traditional essential oil products.
- Trial name
- NCT02884817
- Testing
- Experimental: essential oils and ELA, Water
- Where
- Norway
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Smoking, Cigarette
Smoking and Peptidoglycan Recognition Protein-1 and Initial Periodontal Therapy
A total of 40 patients with CP (20 smokers (S+CP) and 20 nonsmokers (S-CP)) and 40 periodontally healthy subjects (20 smokers (S+PH) and 20 nonsmokers (S-PH)), comprising 80 subjects, were included in this study.
- Trial name
- NCT03915730
- Testing
- Initial periodontal therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Healthy
Clinical Efficacy of Single-Use of Peroxyl Mouthwash for Reducing Bacteria Saliva and Bioaerosol Contamination Phase 2
To evaluate the antibacterial efficacy of a commercial mouthwash containing 1.5% hydrogen peroxide in reducing the levels of bacteria in bioaerosols generated by dental prophylaxis.
- Trial name
- NCT04717063
- Testing
- Peroxyl Oral Product
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
Evaluation of Air Polishing With Ultrasonic Debridement in the Treatment of Initial Periodontal Pockets
Clinical evaluation of using erythritol powder as air polishing with ultrasonic scaling and root planing in the treatment of initial periodontal pockets.
- Trial name
- NCT03863093
- Testing
- Electro Medical Systems AIRFLOW®, Electro Medical Systems Piezo
- Where
- Syria
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Syrian Private University
Periodontitis, Gingivitis
Regulatory T Cell With Related Interleukins in Periodontal Disease Progression
T Regulatory cells which suppressor subset of T cells and related cytokines remain in blood and infiltrates into the tissue under need.
- Trial name
- NCT06135116
- Testing
- Flow Cytometric Detection of Regulatory T Cells and Cytokines analysis by ELISA
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Periodontal Diseases
Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective
The goal of this observational study is to evaluate non-surgical periodontal treatment in women and men with periodontitis with and without obesity.
- Trial name
- NCT06261723
- Testing
- non-chirurgical periodontal treatment
- Where
- 2 sites in Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Milagros Rocha Barajas
Dental Caries, Bleeding on Probing
Evaluating Methods of Dental Health Instructions on the Oral Health Indices of 12-18-year-old Patients With Fixed Orthodontics
The goal of this clinical trial is to learn which type of oral health education works best to help 12-18-year-old participants with fixed orthodontic appliances (braces) keep their mouths healthy.
- Conditions
- Dental Caries, Bleeding on Probing, Gingival Index, Plaque Index
- Trial name
- NCT07667283
- Testing
- Verbal Oral Hygiene Instruction, Pamphlet-Based Oral Hygiene Instruction, Video-Based Oral Hygiene Instruction
- Where
- Iran
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Gingival Recessions
Vestibular Incision Subperiosteal Tunnel Access (VISTA) Technique Versus Coronally Advanced Flap (CAF) Combined With a Connective Tissue Graft for the Treatment of Maxillary Gingival Recessions
Gingival recession (GR) is a common oral health problem that causes sensitivity, esthetic concerns and hygiene problems. Successful root coverage can be achieved by various surgical techniques.
- Trial name
- NCT06755294
- Testing
- Vestibular incision subperiostal tunnel technique, CAF
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
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