Clinical trials: Gingiva Disorder
Gingivitis, Plaque
Clinical Study of Toothpaste Containing Zinc Lactate as Compared to Colgate Cavity Protection Toothpaste.
The objective of this six-month clinical research study is to evaluate the clinical efficacy of two dentifrices - Toothpaste containing zinc lactate and Colgate Cavity Protection Toothpaste in reducing gingivitis and dental…
- Trial name
- NCT06563518
- Testing
- Meridol, Colgate Cavity Protection
- Where
- Thailand
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
White Spot Lesion of Tooth, Gingival Inflammation
EFFECTIVENESS of WATER FLOSS in PLAQUE REMOVAL and PREVENTION of WHITE SPOT LESIONS in ORTHODONTIC PATIENTS: a RANDOMISED CONTROLLED CLINICAL TRIAL
This clinical trial aims to learn if water floss is as efficient as other interdental cleaning tools and can prevent plaque accumulation and white spot lesions (WSLs) in orthodontic patients.
- Conditions
- White Spot Lesion of Tooth, Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- WATER FLOSS (NCT06752291)
- Testing
- water flosser
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Thin-gingiva, Mucogingival Deformity on Edentulous Ridge
Harvest of Free Gingival Grafts With or Without the Application of Hemostatic Sutures
Randomized, single-center trial with 2 parallel arms and a 1:1 allocation ratio, with the aim of comparing clinical and microvascular healing and patients related outcomes, which follow the harvest of a free gingival graft, where…
- Conditions
- Thin-gingiva, Mucogingival Deformity on Edentulous Ridge, Gingival Recession
- Trial name
- NCT05381623
- Testing
- Simplified suture-less approach, Application of hemostatic sponges and compressive sutures
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Universidad Complutense de Madrid
Gingival Recession, Mucogingival Surgery, Gingival Recession
Combined Bilaminar Tunnel Technique in Treating Difficult Gingival Recessions
The goal of this clinical trial is to learn if the combined bilaminar tunnel technique works to treat anatomically difficult gingival recessions.
- Conditions
- Gingival Recession, Mucogingival Surgery, Gingival Recession, Root Coverage
- Trial name
- NCT07616960
- Testing
- mucogingival surgery
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Choying Lin
Chronic Periodontitis
Identification of EMT Indicators in Healthy and Periodontally Diseased Gingival Samples
The current study focuses on the localization and quantitative assessment of growth factors and cytokines related to the EMT process found in the human gingival tissue samples taken from periodontally diseased individuals…
- Trial name
- NCT03462953
- Testing
- Gingival tissue samples will be harvested
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Recession, Gingival, Bone Loss in Jaw
L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant Placement
comparison between L-prf and connective tissue with dental implant
- Trial name
- NCT07102758
- Testing
- L-PRF with dental implant and customized healing abutment, Connective tissue with dental implant and customized healing abutment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Periodontitis
Impact of Guided Biofilm Therapy on Epithelial and Mesenchymal Biomarkers in Periodontitis Patients
The goal of this clinical trial is to investigate the clinical and biochemical effects of the guided biofilm therapy protocol as an alternative to the conventional non-surgical periodontal therapy in patients with periodontitis.
- Trial name
- NCT07286916
- Testing
- Root surface debridement, Guided Biofilm Therapy
- Where
- Iraq
- Volunteers
- 18 people
- Sponsor
- University of Baghdad
Periodontal Diseases, Periodontitis
Validity of a Self-reported Questionnaire for Periodontal Status in a Saudi Population
This observational study will evaluate the accuracy of a self-reported periodontal questionnaire in adults attending screening appointments in Abha, Saudi Arabia.
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis
- Trial name
- NCT07397104
- Testing
- Self-reported periodontal questionnaire and clinical periodontal examination (reference standard)
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Root Resorption, Orthodontic Appliance Complication
Proteomics and Orthodontic Root Resorption
The majority of previous studies for early detection of Orthodontically Induced Inflammatory Root Resorption (OIIRR) were conducted to assess individual biomarkers which are representative of single biological pathway.
- Conditions
- Root Resorption, Orthodontic Appliance Complication, Orthodontic Pathological Resorption of External Root, Gingival Diseases
- Trial name
- NCT04291443
- Testing
- Heavy Force (225g), Light Force (25g)
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gingivitis
The Efficacy of OrasaltsTM in the Treatment of Gingivitis
Gingivitis is defined as inflammation of the gingiva. It is a common disease that is prevalent in both children and adults, and in both genders .
- Trial name
- NCT02168335
- Testing
- OrasaltsTM, Sea salt
- Where
- South Africa
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Gingival Displacement
Evaluation of Gingival Displacement Methods
This clinical study is being conducted to compare four different methods used to temporarily push the gums away from the teeth during dental procedures.
- Trial name
- NCT07122297
- Testing
- Retraction cord, Retraction paste in capsule form, Retraction paste in injector form
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Gingival Recession
Coronally Advanced Flap and PRF With or Without Demineralized Freeze-dried Bone Allograft in Gingival Recession
Gingival recession is defined as the apical migration of gingival margin beyond cemento-enamel junction with the exposure of root surface.
- Trial name
- NCT02835430
- Testing
- Coronally advanced flap and PRF with DFDBA, Coronally advanced flap and PRF without DFDBA
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Peri-Implantitis, Peri-implant Mucositis
Peri-implant Conditions Mimic Periodontal Conditions
Except for patients with referred clinical bruxism and uncontrolled medical conditions, the study included 123 implants with implanted fixed prostheses that had lasted at least six months after functional prosthetic loading.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Peri-implant Health, Periodontitis
- Trial name
- NCT06128850
- Testing
- disease
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Periodontal Disease; Gingivitis; Dental Plaque; Malocclusion (Post-orthodontic Treatment)
Digital vs Conventional VFR in Post-Orthodontic Retention
This study is comparing two ways of making a retainer, the clear, removable kind worn after braces to see whether the way it's made affects gum health.
- Trial name
- NCT07760935
- Testing
- Digital Vacuum-Formed Retainer, Conventional Vacuum-Formed Retainer
- Volunteers
- 52 people
- Sponsor
- Ziauddin University
Xerostomia, Xerostomia Following Radiotherapy
GUM Hydral Mouthwash vs Placebo in the Management of Hyposalivation.
There is currently little robust evidence to inform the management of hyposalivation and xerostomia in this population. Although the treatment of xerostomia is very individual, a first-line medication is needed to ameliorate the…
- Trial name
- NCT05103124
- Testing
- Hydral
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Catholic University of the Sacred Heart
Periodontal Diseases
GCF Levels of Chemokines in Periodontitis
This study aimed to determine CCL19/MIP3beta(β) and CCL20/MIP3alpha(α) in the gingival crevicular fluid (GCF) of the patients with different periodontitis phenotypes.
- Trial name
- NCT06291454
- Testing
- Routine periodontal examination
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University
Gingival Recession, Localized
Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects
The goal of this randomized clinical study is to assess the root coverage outcomes and patient morbidity following the treatment of single maxillary recession-type defects using a coronally advanced flap (CAF) combined with a…
- Trial name
- NCT06404762
- Testing
- tSCTG+ CAF, pSCTG+ CAF
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Diabetic Nephropathy Type 2, Type 2 Diabetes
Salivary and Serum Inflammatory Biomarkers in Diabetic Nephropathy by Periodontal Status
Chronic inflammation underlies the bidirectional relationship between diabetes and periodontitis, a process that may be further exacerbated in the presence of diabetic nephropathy.
- Conditions
- Diabetic Nephropathy Type 2, Type 2 Diabetes, Periodontitis, Gingivitis
- Trial name
- NCT07498894
- Testing
- clinical periodontal measurements, serum samples, saliva samples
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Pamukkale University
Gingival Atrophy
Soft Tissue Augmentation Around Dental Implant
Patients were randomly distributed into two groups (G1 and G2), all patients were treated by a submerged dental implant protocol and free gingival graft (FGG) harvested from the palate as follows: Group 1 (G1), received the FGG…
- Trial name
- NCT06238427
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gingivitis, Plaque, Dental
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
The 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the stannous fluoride containing toothpaste (SNAP) compared to Colgate Cavity Protection Toothpaste after 3 and 6 months of…
- Trial name
- NCT06300866
- Testing
- Test, Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
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