Clinical trials: Gingiva Disorder
Periodontitis
The Novel Electrolyzed Water Spray Treatment Mild Periodontitis
The purpose of this study is to test whether spraying the tooth of patients by use of the novel electrolyzed water spray will produce improvement in the condition of mild periodontitis.
- Trial name
- NCT05770258
- Testing
- The novel electrolyzed water spray
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Dove Medical Press Ltd
COPD, Microbial Colonization
Partially Hydrolyzed Guar Gum (PHGG) for Amelioration of Chronic Obstructive Pulmonary Disease (COPD)
Some components of the diet could promote the growth of certain bacterial strains present in the intestine, which are closely associated with benefits for host health.
- Conditions
- COPD, Microbial Colonization, Respiratory Tract Disease
- Trial name
- NCT05126654
- Testing
- Partially Hydrolyzed Guar Gum (PHGG)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
Gingival Recession
Effect Of Microneedling With Coronally Advanced Flap For Management of RT1 Gingival Recession In Thin Gingival Phenotype
The goal of this clinical trial is to explore the effect of microneedling to increase the gingival tissue thickness which could improve the outcome of root coverage in coronally advanced flap procedure in thin gingival phenotype.
- Trial name
- RT1 (NCT06988839)
- Testing
- Microneedling followed by coronally advanced flap, Coronally advanced flap with connective tissue graft
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Diseases
Placebo Controlled Trial of a Titanium Dioxide Semiconductor Toothbrush on Mild-to-moderate Gum Disease
The effects on indices of gingivitis/periodontitis will differ between study arms in which the titanium dioxide semiconductor toothbrush is used, compared to an otherwise identical toothbrush with an inert resin core in place of…
- Trial name
- NCT00167466
- Testing
- Soladey-3 toothbrush
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Saskatchewan
Gingival Enlargement
The Effect of Ozone Therapy on Gingivoplasty
Ozone therapy after gingivectomy and gingivoplasty has been found to reduce patients' pain levels and positively impact their quality of life.
- Trial name
- NCT06753305
- Testing
- Gingivectomy and gingivoplasty surgery and periodontal paste +ozone therapy application, Gingivectomy and gingivoplasty surgery and periodontal paste application
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kutahya Health Sciences University
Gingival Recession
A Pilot Study of CelTx(TM) (Apligraf®) in the Treatment of Gingival Recession Requiring Root Coverage
The purpose of this study is to evaluate CelTx as an alternative to tissue from the palate in the treatment of subjects with Miller Class I or II recession defects who desire root coverage.
- Trial name
- NCT00679081
- Testing
- CelTx, Autologous sub-epithelial connective tissue graft
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Organogenesis
Caries; Enamel, Gingivitis
Immunological and Regenerative Implications of Corrosion of Dental Materials
During orthodontic treatment intraoral corrosion results with release of nickel and titanium ions from orthodontic appliances in surrounding tissues.
- Trial name
- IMUNODENT (NCT03334461)
- Testing
- Exposure to oral antiseptics or enamel remineralisation agent
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Gingivitis
Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs
Aim: To evaluate the effectiveness on tissue response of the new nutritional supplement made of Oligomeric Proanthocyanidins (OPCs) in induced gingivitis after 21 days of use.
- Trial name
- NCT02515929
- Testing
- Oligomeric Proanthocyanidins
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Seville
Gingival Recession
Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects
This study deals with coverage of multiple denuded roots. The current standard treatment requires surgical correction and uses soft tissue taken from the roof of the mouth to enhance results.
- Trial name
- NCT01440426
- Testing
- Autologous connective tissue graft with rotated papilla flap, Collagen matrix construct (Mucograft)
- Where
- 13 sites in Belgium, Germany and 4 more
- Volunteers
- 187 people
- Sponsor
- Maurizio Tonetti
Plaque, Dental, Gingivitis
Efficacy of a Toothpaste in Reducing Plaque, Gingivitis, and Gingival Bleeding
To assess the efficacy of a toothpaste containing chitosan in reducing plaque, gingivitis, and gingival bleeding, compared with Colgate Cavity Protection Toothpaste
- Trial name
- NCT07499115
- Testing
- Toothpaste containing chitosan, Colgate Cavity Protection Toothpaste
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Recession, Emdogain
Gingival Recession Coverage With and Without Emdogain
Enamel matrix proteins have been shown to play a crucial role during tooth development and its supporting tissues. This is used in periodontal surgery where regeneration of lost tissues around the teeth is intended.
- Trial name
- NCT02230787
- Testing
- Recession coverage without Emdogain, Recession coverage with Emdogain
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Dental Caries, Gingival Inflammation
DETERMINATION OF THE EFFECTS OF STAINLESS STEEL CROWNS CEMENTED WITH RESIN CEMENTS ON INTERLEUKIN-10, 12, 18 LEVELS IN GINGIVAL CREVICULAR FLUID
This split-mouth clinical study aimed to evaluate the early effects of stainless steel crowns cemented with self-adhesive resin cement and high-viscosity glass ionomer cement on clinical periodontal parameters and interleukin-10…
- Conditions
- Dental Caries, Gingival Inflammation, Periodontal Response to Dental Restorative Materials
- Trial name
- SSC-CYTO (NCT07421206)
- Testing
- Self-Adhesive Resin Cement Group, High-Viscosity Glass Ionomer Cement
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Gingival Recession
Collagen Matrix With Tunnel Technique Compared to CTG for the Treatment of Periodontal Recessions
The aim of this study is to compare the efficacy of dental root coverage using the tunnel technique with connective tissue graft (CTG) and the same technique with collagen matrix for treatment of multiple gingival recessions…
- Trial name
- NCT02632240
- Testing
- Surgery:The tunnel technique for covering gingival recession
- Where
- Poland
- Volunteers
- 28 people
- Sponsor
- Medical University of Silesia
Gingivitis
A Proof-of-principle Clinical Study Investigating the Efficacy of an Experimental Dentifrice Containing Sodium Bicarbonate and Sodium Hyaluronate on Gingivitis
The aim of this study is to develop a daily use toothpaste containing sodium bicarbonate, sodium hyaluronate and sodium fluoride with the intention of providing improved/ fast gum healing.
- Trial name
- NCT04737538
- Testing
- Experimental Dentrifrice, Positive control dentifrice, Negative control dentifrice
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Periodontitis
Boron Levels, Oxidative Stress, and Inflammation in Periodontitis
This cross-sectional observational study aims to evaluate the relationship between boron levels and oxidative stress, antioxidant defense, and inflammatory markers in individuals with periodontitis.
- Trial name
- NCT07775378
- Testing
- Biochemical Assessment of Saliva and Gingival Tissue
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Inflammation, Periodontal Disease
Correlation Between Oral Health and Systemic Inflammation (COHESION)
COHESION is a randomized trial targeting reduction of systemic inflammation through an oral hygiene regimen incorporating a plaque-disclosing toothpaste and a control toothpaste.
- Conditions
- Inflammation, Periodontal Disease, Gingivitis
- Trial name
- COHESION (NCT03641989)
- Testing
- Plaque disclosing toothpaste, Non-plaque disclosing toothpaste
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Marshfield Clinic Research Foundation
Periodontitis, Dental Anxiety
The Effect of Virtual Reality Glasses on Dental Anxiety Control
In this clinical study, it was aimed to evaluate whether there is a decrease in patient anxiety by applying virtual reality glasses, which are the product of new technology, during scaling and root planing treatment.
- Conditions
- Periodontitis, Dental Anxiety, Dental Fear, Gingivitis
- Trial name
- NCT05038540
- Testing
- Scaling and root planing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Gingival Recession, Lack of Keratinized Attached Peri-implant Mucosa
Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix
This study is to compare the two techniques to achieve change in the tissue quality at areas of lack of Keratinized Tissue (KT) using soft tissue grafting with autogenous graft material (Free Gingival Graft)(FGG) vs Strip…
- Conditions
- Gingival Recession, Lack of Keratinized Attached Peri-implant Mucosa, Thin Gingiva
- Trial name
- NCT04920136
- Testing
- Strip Free gingival graft (SGG) + Acellular Dermal Matrix graft (ADM), Free Gingival graft
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cardiovascular Disease, Periodontal Disease
Impact of Gum Infection on Heart Disease
The purpose of this study is to determine the effect of gum infection on parameters of cardio-vascular disease.
- Trial name
- NCT00093236
- Testing
- Early Periodontal Treatment, Usual Dental Hygiene
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Boston University
End Stage Renal Disease (ESRD)
The Effect of Gum Arabic (GA) on Residual Renal Function in Adult Dialysis Patients in Abu Dhabi
Gum Arabic (GA), derived from Acacia trees, has shown potential benefits in metabolic, renal, and inflammatory conditions. This study explores the impact of GA on residual renal function in end-stage renal disease (ESRD) patients…
- Trial name
- GAESRD (NCT06836206)
- Testing
- Gum Arabic, Water
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Abu Dhabi Health Services Company
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