Clinical trials: Gingiva Disorder
Mouth Diseases, Periodontal Inflammation
Evaluation of Biomarkers Levels in Gingival Crevicular Fluid, Saliva and Serum for Different Periodontal Diseases
The aim of this study is; detection of interleukin(IL)-38, IL-36 gamma(γ) , IL-17 and matrix metalloproteinase(MMP)-9 levels in gingival crevicular fluid (GCF), saliva and serum samples of periodontally healthy, gingivitis and…
- Conditions
- Mouth Diseases, Periodontal Inflammation, Periodontal Diseases
- Trial name
- NCT05435131
- Testing
- GCF obtaining, Saliva Obtaining, Serum obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Molar-Incisor Hypomineralization, Peridontal Disease
Molar-Incisor Hypomineralization Vs Periodontal Health
Background: To investigate the effect of molar incisor hypomineralization (MIH) on periodontal health, to evaluate the relationship between gingival crevicular fluid (GCF) volume, and GCF biomarkers such as matrix…
- Trial name
- MIH (NCT06764043)
- Testing
- Clinical evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Plaque, Dental
Efficacy of a Eugenol-based Product to Improve the Quality of Toothbrushing and Relieving Gum Discomfort Areas
The objective of this study is to evaluate the efficacy of a eugenol-based product in improving the quality of toothbrushing and relieving areas of gingival discomfort.
- Trial name
- NCT06366568
- Testing
- fluoride toothpaste containing 1450 ppm of MFP in a PCC base and eugenol gum product, fluoride toothpaste containing 1450 ppm of MFP in a PCC base
- Where
- Germany
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Open Wound of Palate Without Complication, Pain, Postoperative
The Effect of Ozone Therapy on Pain Perception After Free Gingival Graft Surgery in Patients With Mucogingival Defects
Gaseous ozone (O3-triatomic oxygen) is the third-strongest oxidizing agent worldwide. It influences the cellular and the humoral immune system, by stimulating the proliferation of immunocompetent cells and the synthesis of…
- Conditions
- Open Wound of Palate Without Complication, Pain, Postoperative, Free Gingival Grafts, Mucogingival Defects
- Trial name
- NCT05291715
- Testing
- Ozone generator device (Ozone DTA-APOZAa-enterprize CO9-Taiwan, R.0.C)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Omaima Mossad Mahmoud AL-Sherbini
Mucositis
Surgical Protocol for Prevention of Mucositis
The main goal of implant therapy is to obtain long-term peri-implant health. Among local risk factors in the etiology of peri-implant diseases the absence of keratinized tissue (KT) around the implant has been reported.
- Trial name
- NCT04628520
- Testing
- Free gingival graft, Collagen matrix, Maintenance
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Caries, Tooth Decay
Improving Oral Health With Serious Games
This study investigated if computer games can be effective at changing the way children take care of their teeth. We a museum exhibit with 3D virtual reality games called "Attack of the S.
- Conditions
- Caries, Tooth Decay, Cavities, Gingivitis
- Trial name
- AOTSM (NCT02027597)
- Testing
- Attack of the S. Mutans, Follow-up, SnowWorld
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Washington
Oral Hygiene, Photographs
Effect of Pre-treatment Photographs on Oral Hygiene Maintenance in Orthodontic Patients
Dental photography is an essential component of orthodontic treatment. Photographs enable the clinician to keep record of different stages of treatment.
- Trial name
- NCT06010797
- Testing
- Showing Pre-treatment photographs of the patient
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rehmat Memorial Post Graduate Dental Teaching Hospital
Gingivitis
The Effect of Probiotics on Gums Health and Bad Breath
the study is about using healthy bacteria to improve the overall gingival and overall health and prevent or decrease the bad odor of the mouth caused by bad bacteria
- Trial name
- NCT06910397
- Testing
- Probiotic Arm
- Where
- Iraq
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingival Inflammation, Dental Plaque Accumulation
Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash
This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash).
- Trial name
- NCT07824388
- Testing
- Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Gingival Recession
Patient Satisfaction After Root Coverage Using VISTA Technique Compared to MCAF Technique With PRF.
VISTA technique with PRF compared to MCAF technique with PRF to treat gingival recession
- Trial name
- NCT03328442
- Testing
- VISTA Technique, modified coronally advanced flap
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Periodontal Disease
Gingival Crevicular Fluid and Salivary Levels of GDF-15, Smad2, Smad5, Smad6, and IL-6 in Patients With Periodontitis
The dysregulation of the transforming growth factor-beta signaling pathway can lead to inflammation and tissue destruction in the pathogenesis of periodontitis.
- Trial name
- NCT07201142
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Melis Yilmaz
Hyperemesis Gravidarum, Nausea Gravidarum
Chewing Gum Containing Vitamin-c to Treat Emesis Gravidarum
Nausea and vomiting is a common complication of pregnancy and occurs in 70-80% of all pregnancies. The symptoms usually start 2-4 weeks after fertilization and peak between the 9th and 16th week of gestation.
- Conditions
- Hyperemesis Gravidarum, Nausea Gravidarum, Vitamin C Deficiency
- Trial name
- NCT04284696
- Testing
- Pregnan-C-Gum(R) chewing gum
- Where
- Austria
- Volunteers
- 126 people
- Sponsor
- Medical University of Vienna
Preterm Birth, Low Birth Weight
Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial
Periodontal disease in pregnant women has been implicated as a potential risk factor for adverse pregnancy outcomes, including being born preterm, small-for-gestational age, and/or low birth weight.
- Conditions
- Preterm Birth, Low Birth Weight, Small Vulnerable Newborn, Small-for-gestational Age
- Trial name
- NCT07553286
- Testing
- A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%))
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gingival Recession
Hyaluronic Acid With Connective Tissue Grafting for Gingival Recession
This study evaluates whether adding 0.8% hyaluronic acid (HA) to connective tissue grafting and coronally advanced flap surgery improves clinical and esthetic outcomes in the treatment of gingival recession.
- Trial name
- NCT07291583
- Testing
- Hyaluronic Acid (0.8%) - Applied over CTG before flap closure (Test group only)., Connective Tissue Graft + Coronally Advanced Flap (CTG + CAF)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi
Missing Teeth
Assessment of Hard and Soft Tissue Changes Following XCM Versus FGG Simultaneous With Delayed Dental Implant Placement
Teeth loss are usually associated with alterations of extraction sockets result in obviously absorbed alveolar ridges and are often accompanied with soft tissue atrophy such as narrow keratinized tissue and a shallow vestibule.
- Trial name
- NCT07080177
- Testing
- Free gingival graft simultaneous with delayed implant placement, Xenogeneic collagen matrix simultaneous with delayed implant placement
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis, Periodontal Disease
Touch-to-Teach Interdental Brush Instruction Versus Conventional Guidance on Gingival Health in Patients With Fixed Dental Prostheses
Why is this study being done? People with dental crowns often develop inflamed gums because bacteria accumulate in the tight spaces between teeth that a regular toothbrush cannot reach.
- Conditions
- Gingivitis, Periodontal Disease, Fixed Dental Prosthesis, Dental Plaque
- Trial name
- NCT07636954
- Testing
- Touch-to-Teach interdental brush instruction, Conventional oral hygiene instruction
- Where
- United Arab Emirates
- Volunteers
- 32 people
- Sponsor
- Gulf Medical University
Gingival Recession
Diode Laser for Harvesting Gingival Graft
Aims: The aim of present randomized controlled clinical study was to evaluate whether the additional use of diode laser would facilitate the donor surgery, improve the palatal wound healing and reduce post-operative morbidity…
- Trial name
- NCT02441127
- Testing
- diode laser group, scalpel control group
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Cukurova University
Peridontal Disease
Investigation of Lipoxin A4, Annexin A1 and Interleukin-1 Beta Levels in Individuals With Periodontitis.
Since the researchers thought that Annexin A1, Lipoxin A4 and IL-1 Beta parameters, which have been found to be related to inflammatory conditions, may increase in periodontitis, a common inflammatory gum disease, we wanted to…
- Trial name
- Lipoxin A4 (NCT06700161)
- Testing
- Obtaining CGF from patients
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Eda Cetin Ozdemir
Liver Cancer
Effect of Smoked Plum and Chewing Gum on Postoperative Bowel Function Following Hepatic Resection
Every patient undergoing surgery in the abdomen, such as hepatic resection, will experience temporary paralysis of bowel function.
- Trial name
- SP/GC-HCC (NCT02649153)
- Testing
- smoked plum, gum chewing
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Gingival Recession
Evaluation of Subepithelial Connective Tissue Graft Versus Acellular Dermal Matrix With Tunnel Technique in Treatment of Multiple Gingival Recessions
The goal of the present study is to compare the amount of root coverage resulting from subepithelial connective tissue graft and acellular dermal matrix associated with tunnel technique among patients suffering from multiple…
- Trial name
- NCT02916186
- Testing
- Acellular Dermal Matrix, Tunnel technique with the subepithelial connective tissue graft
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.