Clinical trials: Gingiva Disorder
Gingival Recession, Gingival Recession, Localized
The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients with Gingival Recession.
Gingival recession is the term used to describe the apical positioning of the marginal gingiva from the enamel-cementum junction.
- Trial name
- NCT05591326
- Testing
- i-PRF application procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Gingivitis
The Assessment of Clinical Efficacy of Topical Application of 5% Thymoquinone Gel for Gingivitis Patients
Gingival diseases occur commonly in the global population and herbal products for its intervention have limited body of research evidence.
- Trial name
- NCT05497895
- Testing
- 5% thymoquinone (TQ) gel, Only SRP-one stage prophylaxis
- Where
- Saudi Arabia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Periodontal Diseases, Gingivitis
Randomized Trial of a Gum Health Formulation
The purpose of this study is to evaluate the safety and efficacy of a newly formulated foaming gel product on gingivitis and/or moderate periodontitis when used with or without the GLO Science accelerating device (GLO Device)…
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis, Halitosis
- Trial name
- NCT03196648
- Testing
- Gingival health formulation in an accelerating device, Gingival health formulation on a toothbrush, OTC fluoride toothpaste
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Glo Science, Inc.
Gingival Recession
Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries
Thin gingival phenotype is one of the major causative factors of gingival recession type 1 which can result in hypersensitivity, discomfort, and compromised esthetics.
- Trial name
- NCT05688293
- Testing
- Connective tissue graft, Free gingival graft, Non surgical
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Relapse, Gingival Recession
RCT for the Effectiveness of 3 Orthodontic Retention Schemes on Post-treatment Stability and Gingival Recession
The present study aims to assess the effectiveness of three different retention schemes used to maintain tooth position after orthodontic treatment with fixed orthodontic appliances (stability) and to evaluate possible…
- Trial name
- OrthRe10tion (NCT02742493)
- Testing
- 0.028 bonded to canines, 0.027 7-strand bonded to all 6, removable Hawley-type
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Plaque, Gingivitis
A Clinical Trial to Test the Effect of Marketed Mouth Rinses on Decreasing Plaque and Gum Inflammation
The reduction of existing plaque and gum inflammation will be evaluated using two marketed mouth rinses along with tooth brushing after 21 days of use compared to a placebo mouth rinse.
- Trial name
- NCT02233998
- Testing
- Mouth Rinse 1, Mouth Rinse 2, Mouth Rinse 3
- Where
- Canada
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Gingival Recession
Platelet Rich Fibrin and Autologous Fibrin Glue
Platelet-rich fibrin (PRF) and Autologous Fibrin Glue (AFG) are fibrin preparation derived from human blood samples and are used in regenerative dentistry.
- Trial name
- NCT03734458
- Testing
- Group A - PRF plus AFG with a CAF, Group B - PRF only with a CAF, Group C - CTG with a CAF
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Heart Failure With Preserved Ejection Fraction
Single-Ascending Dose Study of JK07 in Subjects With HFpEF
A phase 1, randomized, double-blind, placebo-controlled single-ascending dose study to assess JK07 in adult subjects with heart failure with preserved ejection fraction.
- Trial name
- NCT05322616
- Testing
- JK07
- Where
- 7 sites in United States
- Sponsor
- Salubris Biotherapeutics Inc
Periodontitis, Dental Anxiety
The Effect of Virtual Reality Glasses on Dental Anxiety Control
In this clinical study, it was aimed to evaluate whether there is a decrease in patient anxiety by applying virtual reality glasses, which are the product of new technology, during scaling and root planing treatment.
- Conditions
- Periodontitis, Dental Anxiety, Dental Fear, Gingivitis
- Trial name
- NCT05038540
- Testing
- Scaling and root planing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Periodontal Diseases, Periodontal Pocket
Assessment Of Healing After Periodontal Flap Surgery With And Without The Use Of Placental Extracts
All 16 chronic periodontitis (CP) subjects were clinically examined regarding the following clinical periodontal parameters: plaque index (PI), gingival index (GI), bleeding index (BI), Pocket Probing Depth (PPD) and Relative…
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis
- Trial name
- NCT05936450
- Testing
- delivery of placentrex gel after open flap debridement, Open Flap Debridement
- Where
- India
- Volunteers
- 16 people
- Sponsor
- Dr Prabhuji MLV
Periodontal Diseases
Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession
This study compares the efficacy of root coverage achieved by the Pinhole Surgical Technique (PST) technique and the Connective Tissue Graft (CTG) technique in the treatment of Miller class I and II gingival recession defects.
- Trial name
- NCT04356391
- Testing
- Connective Tissue Graft Technique, Pinhole Surgical Technique
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- State University of New York at Buffalo
Gingival Recession
Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate…
- Trial name
- NCT03695549
- Testing
- CAF + (A-PRF), CAF+SCTG
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Diseases
Collection of Gingival Crevicular Fluid From Periodontitis Patients
To collect GCF (gingival crevicular fluid) samples from diseased patients suffering only from gingivitis and/or periodontitis.
- Trial name
- NCT00763048
- Testing
- Fluoride, Fluoride, triclosan
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
RT2 Gingival Recession
Comparing Deepithelialized Free Gingival Graft Versus Subpithelial Connective Tissue Graft With Tunneling Technique in Treating RT2 Gingival Recession
Complete coverage of the recession complemented with pleasing esthetics and minimal probing measures are the main goals of root coverage procedures.
- Trial name
- NCT04104087
- Testing
- tunneling technique with sub epithelial connective tissue graft or deepithelialized free gingival graft.
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Inflammation, Periodontal Disease
Advanced Oxidation Protein Product and Monocyte Chemoattractant Protein-1 in Periodontal Disease
This study investigates the levels of advanced oxidation protein product and monocyte chemoattractant protein-1 in gingival crevicular fluid in periodontal disease and health.
- Trial name
- NCT02848378
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Dental Caries, Probiotics
Effect of Probiotics on Oral Homeostasis During Sugar Stress
The present study is a double-blinded randomized clinical trial with a duration of 28 days.
- Conditions
- Dental Caries, Probiotics, Gingivitis
- Trial name
- NCT05073393
- Testing
- Sugar stress
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Gingivitis
Effectiveness of Propolis Mouthwash on Gingivitis
Mouthrinses have been in used for centuries as breath fresheners, medicaments, and antiseptics. Recently, propolis has caught the eyes of dentists worldwide and researches are being carried out to infuse the usage of propolis in…
- Trial name
- NCT04032548
- Testing
- Propolis mouthwash, Chlorhexidine mouthwash
- Where
- Malaysia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mahsa University
Gingivitis
Comparisons of Efficacy of Triphala and Chlorhexidine Mouthwash Against Plaque Accumulation and Gingivitis.
Gingivitis is one of the commonly prevalent oral diseases worldwide which is caused by the bacterial biofilm adhering to the teeth surfaces. Chlorhexidine is the antimicrobial agent most familiar to dental professionals.
- Trial name
- NCT07426393
- Testing
- 6% Triphala mouthwash, .2% chlorhexidine mouthwash
- Where
- Bangladesh
- Volunteers
- 220 people
- Sponsor
- Bangladesh Medical University
Palatal Neoplasms, Lip Neoplasm
Clinical Evaluation of the OncAlert RAPID in Subjects Presenting for Evaluation and/or Initial Biopsy; Impact on Decision-Making
Objectives Validate the OncAlert® RAPID Test by demonstrating that NPV > (1 -prevalence). Evaluate the independent and associated contribution of readily available clinical variables including age, race, gender, HPV status…
- Conditions
- Palatal Neoplasms, Lip Neoplasm, Gingival Neoplasms, Leukoplakia, Oral
- Trial name
- NCT03239834
- Testing
- OncAlert
- Where
- 26 sites in United States
- Volunteers
- 893 people
- Sponsor
- Vigilant Biosciences, Inc.
Gingival Recession, Gingival Recession, Localized
Coronally Advanced Tunnel Combined With Xenogenic Dermal Matrix and L-PRF
Gingival recession is the exposure of the root surface due to the gum margin moving away from the crown of the tooth. It's common in adults and becomes more prevalent and severe with age.
- Conditions
- Gingival Recession, Gingival Recession, Localized, Mucogingival Defects
- Trial name
- CAF+XADM (NCT06634043)
- Testing
- Coronally Advanced Tunel + ADM (Novomatrix®), Coronally Advanced Tunel + ADM (Novomatrix®) + L-PRF
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Andres Matteo Pascual La Rocca
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