Clinical trials: Gingiva Disorder
Gingival Recession
Evaluation of the Inflammatory and Healing Profile After Root Coverage With Emdogain®
The purpose of this study was the evaluation of inflammatory and healing profile after root coverage using of Enamel Matrix Derivative.
- Trial name
- NCT03059966
- Testing
- Microsurgery technique for root coverage, Microsurgery technique for root coverage associated to EMD
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Nutritional and Metabolic Diseases
FaibaLite - Reduce Weight, One Bite at a Time
This study aims to evaluate the suitability of a fiber-enriched chewing gum as a practical and accessible approach to support healthy body weight management.
- Trial name
- NCT07045766
- Testing
- FibreGum chewing gum
- Sponsor
- University of Bern
Gingivitis
A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride
The purpose of this study is to evaluate and compare the gingival health of a test dentifrice (0.454% weight by weight [w/w] stannous fluoride) to a negative control dentifrice by comparing modified gingival index, bleeding index…
- Trial name
- NCT04123665
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Periodontal Diseases, Obesity, Morbid
Gingival Crevicular Fluid of Adiponectin and Resistin As Predictable Implement in Staging and Grading System of Periodontitis
The goal of this clinical trial is to evaluate the relationship between obesity and gingival crevicular fluid resistin and adiponectin in periodontitis patients as well as assess the effect of non-surgical periodontal therapy on…
- Trial name
- NCT06604013
- Testing
- non-surgical full-mouth periodontal therapy without using adjunct disinfectants, GCF level of adiponectin and resistin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Gingivitis
Homemade Herbal Mouthwash in Gingivitis. A Randomized Clinical Trial.
Gingivitis is a very common oral disease that may progress to the more destructive periodontitis if not treated. As oral plaque is a key player in gingivitis, plaque control by professional scaling and oral hygiene measures…
- Trial name
- NCT07401069
- Testing
- Chlorhexidine 0,12%, herbal Mouthwash
- Volunteers
- 12 people
- Sponsor
- Cairo University
Alveolar Bone Loss, Peri-Implantitis
Radiological Bone Loss on Different Levels of Dental Implants
One of the criteria used for long-term implant success is the evaluation of radiographic bone loss. It is known that the keratinized mucosa over the alveolar crest forms a protective barrier against inflammatory infiltration.
- Conditions
- Alveolar Bone Loss, Peri-Implantitis, Bone Loss in Jaw
- Trial name
- NCT05595746
- Testing
- dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Laser Burn, Gingival Disease
Comparison of Sample Biopsy Using Scalpel or Er:YAG Laser
For certain changes in the oral mucosa a histopathological examination of the affected tissue is indicated to confirm the diagnosis. The gold standard is the biopsy by scalpel.
- Conditions
- Laser Burn, Gingival Disease, Biopsy Wound
- Trial name
- NCT03638973
- Testing
- Biopsy
- Where
- Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Gingival Recessions, Gingival Recession, Mucogingival Surgery
Optimizing Clinical Outcomes in CAF + SCTG: the Impact of Compressive Sutures
This randomized controlled clinical trial aims to evaluate the additional effect on clinical outcomes of compressive sutures associated with coronally advanced flap (CAF) and subepithelial connective tissue graft (SCTG) for the…
- Conditions
- Gingival Recessions, Gingival Recession, Mucogingival Surgery, Suture
- Trial name
- NCT06701786
- Testing
- Compressive Sutures (CSs) group, Without Compressive Sutures (WCSs) group
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Smoking ( Cigarette), Periodontitis Stage II
Study of Gum Tissue Proteins in Smokers vs. Non-smokers After Cleaning
The aim of this study is to evaluate how smoking affects the healing process of the gums after treatment. The researchers will measure the levels of two specific proteins (PLAP-1 and Sclerostin) in the gum fluid of patients with…
- Trial name
- NCT07339670
- Testing
- Non Surgical Periodontal Treatment includes post operative mouth wash with Listerine® (ethanol 21.6%, methyl salicylate 0.06%, menthol 0.042%, thymol 0.064% and eucalyptol 0.092%)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Al-Azhar University
Periodontitis, Gingivitis
Herbal Pralines - Oral Health
This randomized, double-blinded, placebo-controlled two-arm, parallel group clinical trial is designed to evaluate the impact of the consumption of two herbal pralines containing 200 mg nitrate on clinical signs of gingival…
- Trial name
- NCT06090851
- Testing
- herbal nitrate Pralines with nitrate, herbal nitrate Pralines without nitrate
- Where
- 2 sites in Germany
- Volunteers
- 44 people
- Sponsor
- Wuerzburg University Hospital
Cleft Lip and Palate, Periodontal Pocket
Periodontal Changes Following Mid Maxillary Distraction
To evaluate the health status of the periodontium and dentition at the distraction osteogenesis site in CLP subjects using mid maxillary distraction (MMD).
- Conditions
- Cleft Lip and Palate, Periodontal Pocket, Attachment Loss, Periodontal
- Trial name
- NCT03686761
- Testing
- A Involvement with the osteotomy site of the surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Periodontal Diseases, Saliva
GCF and Saliva Levels of IL-36α in Periodontal Disease
Interleukin-36 (IL-36), recently identified and members of the IL-1 family, have been reported to be important regulators of host defense against pathogens in the oral mucosa.
- Conditions
- Periodontal Diseases, Saliva, Gingival Crevicular Fluid, Cytokine
- Trial name
- NCT07497828
- Testing
- Collection of fluid samples
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ordu University
Critically Ill, Oral Health Care
Professional Oral Care and Staff Education in Critically Ill Patients
This study evaluated oral health in critically ill patients admitted to two intensive care units in Budapest, Hungary, and examined whether professional oral care and education of intensive care staff could improve oral hygiene.
- Conditions
- Critically Ill, Oral Health Care, Critical Illness, Oral Care Performance
- Trial name
- NCT07831564
- Testing
- Professional Oral Care, Standard Oral Care, ICU Staff Oral Care Education
- Where
- 2 sites in Hungary
- Volunteers
- 161 people
- Sponsor
- Semmelweis University
Gingival Recession
Comparison of Two Flaps for Root Coverage
The aim of this study was to compare clinical, esthetic and patient-centered outcomes of coronally advanced tunnel (TUN) and coronally advanced flap (CAF) both associated with connective tissue graft (CTG) in the treatment of…
- Trial name
- NCT02814279
- Testing
- CAF plus connective tissue graft, Tunnel plus connective tissue graft, Sodium dipyrone
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recessions, Gingival Recession, Mucogingival Surgery
Histological and Clinical Evaluation of De-epithelialized Connective Tissue Grafts Obtained by Different Methods
This randomized controlled clinical study aimed to evaluate the effectiveness of two different de-epithelialization techniques-extraoral scalpel and intraoral radiofrequency (RF)-used in the preparation of de-epithelialized…
- Trial name
- DEEP-RCT (NCT07521566)
- Testing
- Extraoral de-epithelialization Group, Radiofrequency De-epithelialization
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Gingivitis
Anti-Inflammatory Efficacy of Ginger Containing Dentifrice in the Control of Biofilm Induced Gingivitis
The goal of this clinical trial is to test efficiency of using toothpaste containing (Ginger) over a period of three month to control on gingival inflammation and plaque accumulation through measuring the clinical periodontal…
- Trial name
- NCT05868200
- Testing
- Capitano zenzero toothpaste, Colgate total toothpaste
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gingival Recession
Management of Miller Class I & II Gingival Recession
Management of Miller class I \& II gingival recession using coronally advanced flap combined with conventional de-epithelialized free gingival graft versus coronally advanced flap combined with abrasive de-epithelized connective…
- Trial name
- NCT03767309
- Testing
- coronally advanced flap with abrasive de-epithelized graft., coronally advanced flap with de-epithelized graft.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Halla Gamal Mohammed Esmail
Tooth Loss, Recession, Gingival
Use of Leucocyte- and Platelet-rich Fibrin Membranes in Single Implant
The objective of this randomized controlled clinical trial is to evaluate the increase of soft tissue thickness around single implants installed in maxillary esthetic area with the use of Leucocyte-Platelet rich Fibrin (L-PRF)…
- Trial name
- NCT03660566
- Testing
- Test - Implant with L-PRF, Control - Implant without L-PRF
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession
Platelet-Rich Fibrin Prepared With Titanium in the Treatment of Multiple Gingival Recessions
The aim of this study was to treat the areas with Miller Class I bilateral multiple gingival recession in the maxillary teeth using the Titanium Platelet-Rich Fibrin (T-PRF), an autogenous biomaterial applied in combination with…
- Trial name
- NCT05270941
- Testing
- COMPARISON OF PLATELET-RICH FIBRIN PREPARED WITH TITANIUM AND SUBEPITHELIAL CONNECTIVE TISSUE GRAFT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
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