Clinical trials: Gingiva Disorder
Periodontitis, Gingivitis
PTPIP51-VAPB Complex in the Periodontal Disease
Gum disease, including gingivitis and more advanced periodontitis, is a common condition that damages the tissues supporting the teeth.
- Trial name
- NCT07705048
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inonu University
Dental Plaque, Gingivitis
The Study to Evaluate the Plaque Control and Anti-Gingivitis Efficacy of a Toothpaste in Chinese Population
The aim of this study is to evaluate the efficacy of the test toothpaste compared to a regular fluoride toothpaste in the reducing gingivitis and plaque accumulation in Chinese participants with plaque-induced gingivitis.
- Trial name
- NCT07816406
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- HALEON
Periodontitis
Impact of Non-surgical Periodontal Treatment on Targeted Metabolomics
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with…
- Trial name
- NCT07740447
- Testing
- Probing depth reduction
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Catania
Gingival Recession
Comparison of Two Techniques in Gingival Recession Treatment. One-year Clinical Follow-up Study
42 patients were treated either with E-CTG (N=20) or SCAF (N=22). The recordings included clinician-based (recession depth, recession width, probing depth, clinical attachment level, keratinized tissue width, tissue thickness…
- Trial name
- NCT04109794
- Testing
- E-CTG
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Gum Disease
Periodontal Treatment and Psychology
There is a relationship between depression and periodontal disease. This relationship may be double-sided. A psychological state such as anxiety, depression, body image, and self-esteem may be affected from the symptoms of…
- Trial name
- NCT03190512
- Testing
- Psychological measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people
- Sponsor
- Ozge Gokturk
Chronic Inflammatory Gingival Enlargement, Gingival Enlargement
Wound Healing After Gingivectomy
Gingival enlargement caused by chronic inflammation may require surgical intervention when non-surgical periodontal therapy is insufficient.
- Conditions
- Chronic Inflammatory Gingival Enlargement, Gingival Enlargement, Gingival Hyperplasia
- Trial name
- OZONE-GING (NCT07517328)
- Testing
- Gaseous ozone application, Gingivectomy/gingivoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ataturk University
Oral Biofilm, Periodontitis
Methodology Antiseptic Application, Influence on Oral Biofilm.
The study has the objective to compare two different methodology of application the antiseptic on the oral biofilm will be formed during 48h in situ on a specific device.
- Conditions
- Oral Biofilm, Periodontitis, Gingivitis
- Trial name
- NCT02267239
- Testing
- essential oils, immersion, Chlorhexidine, immersion, essential oils, mouthwash
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Periodontitis, Gingivitis
GCF Bax and Bcl-xl Levels in Periodontitis
Intrinsic apoptosis pathway plays a critical role in the host immune defense and inflammation and its dysregulation is involved in various chronic diseases. Bcl-2 protein family primarly mediates this mitochondrial pathway.
- Conditions
- Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT06443372
- Testing
- Clinical periodontal measurements, GCF sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Periodontal Diseases, Periodontitis
Evaluation Of The Efficacy Of Subgingival Application Of Lovastatin Gel As An Adjunct To Non-Surgical Treatment Of Periodontitis In Generally Healthy Smokers And Non-Smokers Patients in Central Europe.
The aim of the study is to evaluate how a gel (1.2% lovastatin) applied under the gum improves the results of classic periodontal treatment (SRP-scaling, root planing).
- Conditions
- Periodontal Diseases, Periodontitis, Periodontal Disease, Smokers
- Trial name
- RCT (NCT07282756)
- Testing
- Subgingival application of 1.2% lovastatin
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Medical University of Silesia
Generalized Chronic Periodontitis, Osteoporosis
A Study to Assess the Disturbances in Calcitonin Gene in Patients With Gum Disease and Osteoporosis
Osteoporosis and Periodontitis are multifactorial diseases which share common risk factors.The aim of the present study is to ellucidate polymorphisms in Calcitonin receptor gene? in patients with Osteoporosis and Periodontitis.
- Trial name
- CTROP (NCT02273128)
- Testing
- CTR Gene
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Gum Inflammation, Periodontal Diseases
Improving Gum Health Among Older Adults Using AI Based mHealth for Personalized OHI
Background: Many older adults in Hong Kong lack thorough tooth cleaning and regular dental check-ups, which can lead to plaque-induced gum diseases and systemic health issues.
- Conditions
- Gum Inflammation, Periodontal Diseases, Oral Hygiene, Oral Health
- Trial name
- NCT07187453
- Testing
- Personalized Oral Hygiene Advice using AI assisted mHealth Tool by Non-Dental Personnel
- Where
- Hong Kong
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mammary Neoplasm, Human, Periodontal Diseases
Cytokine Profiles in Breast Cancer Patients Undergoing Chemotherapy
Aim: This study evaluated the effects of non-surgical periodontal therapy (NSPT) on the cytokine profile and the correlation to clinical parameters of patients undergoing chemotherapy for breast cancer.
- Conditions
- Mammary Neoplasm, Human, Periodontal Diseases, Chemotherapy Effect
- Trial name
- NCT03244943
- Testing
- Non surgical periodontal Treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gingivitis
A Clinical Trial to Evaluate Long-term Efficacy and Safety of Lozenges Containing Lactobacilli Reuteri (Prodentis™) on Gingivitis
The purpose of this study is to evaluate the long-term efficacy and safety of lozenges containing probiotics in reducing gingivitis. The primary purpose of this study is to support claims from U.S.
- Trial name
- NCT01811316
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Sunstar Americas
Toothbrush, Gingivitis
Full-mouth Electronic Toothbrush vs. Conventional Electronic Toothbrush
The goal of this randomized, masked-examiner clinical trial is to investigate a full-mouth electronic toothbrush (FMET). The three arms are: 1) FMET + American Dental Association (ADA) approved dentifrice, 2) conventional…
- Conditions
- Toothbrush, Gingivitis, Plaque
- Trial name
- NCT06561204
- Testing
- FMET
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Gingival Recession
Collagen Matrix With Tunnel Technique Compared to CTG for the Treatment of Periodontal Recessions
The aim of this study is to compare the efficacy of dental root coverage using the tunnel technique with connective tissue graft (CTG) and the same technique with collagen matrix for treatment of multiple gingival recessions…
- Trial name
- NCT02632240
- Testing
- Surgery:The tunnel technique for covering gingival recession
- Where
- Poland
- Volunteers
- 28 people
- Sponsor
- Medical University of Silesia
Gingivitis
A Study Comparing the Interproximal Plaque and Gingivitis Effects of Three Interdental Cleaning Modalities
The purpose of this research study is to compare the interproximal plaque removal ability of Philips Sonicare Interproximal Cleaning Device to floss (Crest Glide) and Waterpik Waterflosser.
- Trial name
- PAU (NCT01307358)
- Testing
- Sonicare Interproximal (IP) Cleaning Prototype
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Recession, Gingival, Bone Loss in Jaw
L-PRF vs Connective Tissue With Customized Healing Abutment in Immediate Implant Placement
comparison between L-prf and connective tissue with dental implant
- Trial name
- NCT07102758
- Testing
- L-PRF with dental implant and customized healing abutment, Connective tissue with dental implant and customized healing abutment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Gingivitis, DMFT Index
Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients
This study is being conducted to explore how motivational interviewing (MI), A patient-centered counseling method, can help improve oral health awareness and practices in adolescents undergoing orthodontic treatment.
- Conditions
- Gingivitis, DMFT Index, Dental Plaque Index, Oral Hygiene Education Methods
- Trial name
- MI-Ortho (NCT07164989)
- Testing
- Motivational Interviewing-Based Counseling, Standard Oral Health Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontal Diseases
Comparison of Free Gingival Graft and Modified Apical Repositioning Flap Techniques
Attached gingiva, a crucial component of the keratinized tissue, plays a vital role in preserving periodontal health. The free gingival graft (FGG) and modified apically repositioned flap (MARF) techniques are frequently used for…
- Trial name
- NCT06253910
- Testing
- Patients selection, Recall visits
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Apical Periodontitis
Evaluation of IL-17, TNF-alpha, RANKL Levels in Gingival Cervicular Fluid
Inflammatory process begins around root apex as a result of bacterial infection of pulp cavity in chronic apical periodontitis. Bone destruction can begin in apical region after immunological reactions at the end of inflammatory…
- Trial name
- NCT05232591
- Testing
- The teeth diagnosed with chronic apical periodontitis
- Volunteers
- 40 people
- Sponsor
- Yuzuncu Yil University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.