Clinical trials: Gingival Condition
Ileus
Does Chewing Gum After Elective Laparoscopic Colectomy Surgery Decrease Ileus?
The incidence of ileus after laparoscopic colectomy continues to pose complications for the patient, staff, and the healthcare system.
- Trial name
- NCT00632801
- Testing
- chewing gum
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- State University of New York - Upstate Medical University
Gingival Recession
Platelet Rich Fibrin in the Treatment of Multiple Gingival Recessions
The aim of this randomized controlled clinical study is to evaluate and compare the effectiveness of platelet rich fibrin (PRF) and connective tissue grafts in the treatment of multiple gingival recessions.
- Trial name
- NCT02018120
- Testing
- connective tissue graft, platelet rich fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ege University
Gingival Recession, Generalized
Xenogenic Collagen Matrix for the Treatment of Multiple Gingival Recessions
The primary aim of this study is to evaluate whether the use of a xenogenic collagen matrix (XCM) for the treatment of multiple adjacent gingival recessions (MAGRs) with a multiple coronally advanced flap technique (mCAF)…
- Trial name
- NCT05693753
- Testing
- Use of XCM for the treatment of MAGRs with mCAF technique, Treatment of MAGRs with CTG
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Cross-linked Hyaluronic Acid
Treatment of Buccal Ginvigal Recessions With the Tunnel Technique in Conjunction With Cross-linked Hyaluronic Acid and Subepithelial Connective Tissue Graft. A Randomized Clinical Trial
To evaluate the outcomes of buccal gengival recession type 1 (RT1) treated with the tunnel technique in conjunction with a cross-linked hyaluronic acid and subepithelial palatal connective tissue grafts.
- Trial name
- NCT05436002
- Testing
- With Cross-linked Hyaluronic Acid
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Gingival Diseases
Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.
Clinical research study to determine the anti-plaque efficacy of prototype dentifrices via a 4-day brushing regiment
- Trial name
- NCT00966953
- Testing
- Fluoride, Triclosan/Fluoride toothpaste, antibacterial plant extract
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Recession, Smoking
The Role of Smoking and Gingival Crevicular Fluid Markers on Coronally Advanced Flap Outcomes
Cigarette smoking is a patient-related factor that can affect healing of periodontal tissues and the success rate of root-coverage procedures.
- Trial name
- NCT03539939
- Testing
- Coronally Advanced Flap
- Volunteers
- 15 people
- Sponsor
- Ege University
Gingival Recession
Effect Of Microneedling With Coronally Advanced Flap For Management of RT1 Gingival Recession In Thin Gingival Phenotype
The goal of this clinical trial is to explore the effect of microneedling to increase the gingival tissue thickness which could improve the outcome of root coverage in coronally advanced flap procedure in thin gingival phenotype.
- Trial name
- RT1 (NCT06988839)
- Testing
- Microneedling followed by coronally advanced flap, Coronally advanced flap with connective tissue graft
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Infra-bony Periodontal Defect
Effect of Gingival Mesenchymal Stem Cell-Derived Small Extracellular Vesicles in Management of Infra-bony Periodontal Defect
The goal of the study to evaluate whether the adjunctive use of gingival mesenchymal stem cell-derived extracellular vesicles (GMSC-derived EVs) combined with β-tricalcium phosphate (β-TCP) and a collagen membrane results in…
- Trial name
- NCT07867067
- Testing
- Gingival mesenchymal stem cell derived small extracellular vesicles, β-calcium triphosphate (β-TCP) + collagen membrane
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Ain Shams University
Gingivitis
To Investigate the Gingivitis Efficacy of a Stannous Fluoride Dentifrice in a Chinese Population
This single-centre, examiner-blind, randomized, stratified, two-treatment, parallel group clinical study will evaluate the efficacy of a 0.454% w/w stannous fluoride dentifrice compared to a reference dentifrice to control…
- Trial name
- NCT02937636
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingival Recession
Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment
The aim of the trial is to evaluate the effectiveness of coronally advanced flap (CAF)+connective tissue graft(CTG)+platelet-rich fibrin(PRF) combination in Miller I and II recession treatment by comparing with CAF+CTG.
- Trial name
- NCT02397122
- Testing
- platelet-rich fibrin, connective tissue graft, coronally advanced flap
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Gingivitis
Angiogenesis in Periodontal Disease
Gum disease (gingivitis and periodontitis) is a common inflammatory condition affecting the tissues that support the teeth. Smoking is known to make gum disease worse and to affect blood vessel health in the gums.
- Trial name
- NCT07765251
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingival Recession
Root Coverage Comparing an Allograft to a Bovine Xenograft
Root coverage with acellular dermal matrix using the coronally positioned tunnel technique comparing two different donor materials
- Trial name
- NCT02810067
- Testing
- Tunnel + AlloDerm, Tunnel + Novomatrix
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Periodontal Diseases, Sleep
Periodontitis, Sleep Quality and Fatigue
The goal of this observational study is to investigate the association of stage-grade of periodontitis with sleep quality and fatigue and the effect of periodontitis on QoL (Quality of life) in individuals with periodontitis and…
- Conditions
- Periodontal Diseases, Sleep, Fatigue, Quality of Life
- Trial name
- NCT05622019
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Periodontal Disease
Artificial Intelligence for Diagnosing Periodontitis and Monitoring Gingival Inflammation
Background and Objective: Periodontitis and gingivitis are highly prevalent oral diseases that require accurate diagnostic classification and continuous gingival health monitoring.
- Trial name
- NCT07629934
- Testing
- AI-driven Periodontal Diagnostic and Monitoring Algorithms
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Gingival Recession, Platelet Derived Growth Factor
Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix
The present randomized clinical trial is aimed at evaluating the efficacy of recombinant human platelet-derived growth factor in combination with collagen matrix for the treatment of multiple adjacent gingival recessions
- Trial name
- NCT04462237
- Testing
- Root coverage procedures
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Apical Periodontitis, Inflammatory Markers
The Efficacy of Two Different Irrigation Methods on PGE2, NO and IL-6 Levels
Today, debates about the effectiveness of Passive Ultrasonic Irrigation (PUI) and Sonically Activated Irrigation (SAI) techniques used to increase the success of endodontic treatment in chronic apical periodontitis (AP) are still…
- Trial name
- NCT06629545
- Testing
- irrigation activation with PUI, irrigation with sonic activation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Scoliosis
Chewing Gum Facilitates an Earlier Return to Bowel Function in Pediatric Scoliosis Patients: A Prospective Randomized Study
The purpose of this study is to evaluate the effectiveness of chewing gum on reducing post-operative ileus and reducing post-operative gastrointestinal symptoms in pediatric patients undergoing surgical correction of scoliosis.
- Trial name
- NCT02165436
- Testing
- Chewing gum, Control
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Alabama at Birmingham
Periodontitis
Evaluation of Biomarker Levels in Blood, Saliva and Gingival Fluid in Periodontitis
The aim of this study was to compare IMA, MDA, CAT, GSH and ADA levels in gingival crevicular fluid, serum and saliva of periodontally hopeless, periodontitis and gingivitis teeth with healthy control groups.
- Trial name
- NCT04647123
- Testing
- No intervention was applied to the groups the samples will be collected in terms of the diagnosis (hopeless, periodontitis, gingivitis, healthy)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yuzuncu Yil University
Gingivitis, Dental Plaque
Comparing the Efficacy of Toothbrushing With and Without Interproximal Cleaning Aids: A Split-Mouth Trial
The goal of this prospective clinical trial is to evaluate whether adding interproximal cleaning aids (interproximal brush, rubber toothpick, water flosser) to regular tooth brushing improves oral hygiene outcomes and gingival…
- Conditions
- Gingivitis, Dental Plaque, Periodontal Disease
- Trial name
- NCT07725276
- Testing
- Tooth Brushing Alone (Control), Water flosser, Interproximal Brush
- Where
- Lebanon
- Volunteers
- 29 people
- Sponsor
- Saint-Joseph University
Gingival Recession
Xenogeneic Collagen Matrix or Palatal Connective Tissue Graft With a Coronally Advanced Flap in Class III Recessions
The purpose of this multi-center study is to compare the effectiveness of Mucograft versus connective tissue graft in combination with coronal advanced flap for the treatment of Miller class III recessions The connective tissue…
- Trial name
- NCT03344315
- Testing
- experimental: collagen matrix, Active Comparator: autologous connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
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