Clinical trials: Gingival Condition
Music Intervention, Gingival Graft
Effect of a Personalized Sound Intervention During Autogenous Gingival Grafts in Adults
Anxiety feeds the avoidance of dental treatments, leading to the neglect of general oral health. This avoidance is often amplified by the fear of potential pain and dissatisfaction after a dental appointment.
- Conditions
- Music Intervention, Gingival Graft, Anxiety, Pain
- Trial name
- NCT05632679
- Testing
- personalized music intervention, selected audio book
- Where
- 3 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Periodontitis
Effects of Smoking and Vitamin D3 on the Levels of Human Cathelicidin Peptide LL-37
The aims of our study were 1) to evaluate levels of gingival crevicular fluid( GCF) human cathelicidin peptide LL-37 and serum vitamin D3 in smoker and non-smoker patients with chronic periodontitis(CP) 2) to determine whether…
- Trial name
- NCT03923218
- Testing
- LL-37 levels in Gingival crevicular fluid, Serum Vitamin D3 levels, Clinical parameters
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession
Comparison of Conventional Free Gingival Grafts With Partially De-epithelized Free Gingival Grafts
In this study, the conventional SDG method applied to increase the adherent gingival band and partial de-epithelialized SDG methods were evaluated in terms of aesthetics and color compatibility of the recipient area with adjacent…
- Trial name
- NCT04970524
- Testing
- Comparison of conventional free gingival graft versus partial free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Yonca Naziker
Gingival Recession, Generalized
Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
Subepithelial connective tissue graft (SCTG) is considered the gold standard for root coverage treatment. However, it is associated with postoperative morbidity, limited amount of donor tissue, and longer surgical time.
- Trial name
- NCT03207984
- Testing
- Root coverage surgery
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gingival Recession, Localized, Gingival Recession, Plastic Surgery
Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Premandibula.
Multiple techniques can be used for recession coverage. The most common techniques are : tunnel technique (T), coronally advanced flap (CAF) or a combination of both (TCAF).
- Conditions
- Gingival Recession, Localized, Gingival Recession, Plastic Surgery, Gingival Recessions, Gingival Recession, Mucogingival Surgery
- Trial name
- NCT06940050
- Testing
- Coronally advanced flap with a connective tissue graft, Tunneled coronally advanced flap with a connective tissue graft
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- University Hospital, Ghent
Plaque
Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.
To evaluate the efficacy of a stannous fluoride toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.
- Trial name
- NCT07398846
- Testing
- 0.454%Stannous fluoride toothpaste, 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods
Subjects who have shown evidence of gingivitis and plaque will be enrolled in this study. Each subject will be randomly assigned to one of two treatment products.
- Trial name
- NCT07211061
- Testing
- Stannous Fluoride Dentifrice, Sodium Fluoride Dentifrice, electric toothbrush
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Smoking Cessation
Comparison of Pharmacokinetic Profiles of 3 New Nicotine Gum Formulations With a Reference Gum
The purpose of the study is to compare the pharmacokinetic (PK) profiles and assess bioequivalence between three new nicotine gum formulations and a reference nicotine gum in healthy smokers.
- Trial name
- NCT02356913
- Testing
- Nicotine gum
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fertin Pharma A/S
Periodontitis, Gingivitis
Effect of Non-Surgical Periodontal Treatment on Gingival Crevicular Fluid and Serum Biomarker Levels
Periodontal diseases are one of the most common inflammatory diseases. Periodontitis results from products and antigens of microorganisms, which stimulates the innate immune system and local inflammatory response; characterized…
- Conditions
- Periodontitis, Gingivitis, Healthy
- Trial name
- NCT06175624
- Testing
- Clinically Helathy, Gingivitis, Periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Biruni University
Gingival Recession
Taking Measurements of a Gum Graft Site as it Heals
This is an observational study. The participants in this study will be patients at the Graduate Periodontics Clinic at The Ohio State University who are planning to get a gingival graft to treat their gum recession.
- Trial name
- NCT07386457
- Testing
- Gingival graft surgery to treat gingival recession
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ohio State University
Gingival Enlargement
Efficacy of Hyaluronic Acid Gel and Photobiomodulation on Wound Healing After Surgical Gingivectomy
The aim of this study was to evaluate the effect of hyaluronic acid gel after photobiomodulation on the healing of surgical gingivectomy sites
- Trial name
- NCT05787912
- Testing
- Photobiomodulation, Hyaluronic acid after photobiomodulation
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Rheumatoid Arthritis (RA), Periodontitis
Effects of Nonsurgical Periodontal Treatment on GCF Calprotectin and IL-10 in Rheumatoid Arthritis
This study evaluates the relationship between rheumatoid arthritis and periodontal health and examines the effects of nonsurgical periodontal treatment on clinical periodontal findings and gingival crevicular fluid biomarkers.
- Conditions
- Rheumatoid Arthritis (RA), Periodontitis, Gingivitis
- Trial name
- NCT07844564
- Testing
- Non-surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Gingival Overgrowth
Comparison of Dual Digitally Guided vs Conventional Crown Lengthening
This randomized controlled clinical trial aims to evaluate the clinical performance and patient-centered outcomes of dual digitally guided crown lengthening compared to the conventional surgical technique in the management of…
- Trial name
- DIGICROWN (NCT07575087)
- Testing
- Conventional Crown Lengthening, Dual Digitally Guided Crown Lengthening
- Where
- Syria
- Volunteers
- 18 people
- Sponsor
- Arab International University
Periodontal Diseases, Pregnancy Gingivitis
Stress and Gingival Inflammation in Non-pregnant and Pregnant Women
Background: The purpose of the present study is to research whether stress scale scores alter with relationship to gingival inflammation and examine the impact of non-surgical periodontal therapy during pregnancy on the levels of…
- Trial name
- NCT03336957
- Testing
- periodontal treatment
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Melanin Hyperpigmentation
Melanin Recurrence in Scalpel and LASER Gingival Depigmentation in Thin and Thick Phenotypes.
This study aimed to compare melanin pigmentation recurrence, pain perception and wound healing between laser and scalpel surgeries in thin and thick gingival phenotypes.Thirty patients (60 sites) were included in this study.
- Trial name
- NCT06886100
- Testing
- Diode laser, Scalpel No 15
- Where
- Yemen
- Volunteers
- 30 people
- Sponsor
- Thamar University
Gingivitis, Periodontitis
Efficacy of ClōSYS® Sensitive Fluoride Toothpaste and ClōSYS® Sensitive Rinse Regimen on MGI, PI and BOP
90-day, self-controlled, longitudinal, non-blinded clinical trial which will measure changes in clinical parameters in participants with gingivitis and Stage I or II periodontitis who apply ClōSYS® Sensitive Fluoride Toothpaste…
- Trial name
- NCT05258721
- Testing
- ClōSYS® Sensitive Fluoride Toothpaste, ClōSYS® Sensitive Rinse
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rowpar Pharmaceuticals, Inc.
Dental Plaque, Gingival Bleeding
Comparison Between Interdental Brush and Water Floss on Plaque Accumulation and Gingival Inflammation in Patients Undergoing Fixed Orthodontic Treatment.
The goal of this clinical trial is to test the ability of water flosser to remove plaque and reduce gingival inflammation in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07240428
- Testing
- Interdental brush, Water floss
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Gingival Recession
Treatment of Gingival Recession With Tunnel Technique Using Connective Tissue Graft and Injectable Platelet Rich Fibrin
Gingival recession is a common periodontal problem. Consequences include teeth sensitivity, poor esthetics and impaired oral hygiene access.
- Trial name
- NCT06646432
- Testing
- Tunnel with connective tissue graft and injectable platelet rich fibrin, Tunnel with connective tissue graft only
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University
Gingival Recession
Volume-Stable Collagen Matrix Versus Subepithelial Connective Tissue Graft for Multiple Gingival Recessions
Gingival recession is a clinical condition in which the gingival margin is displaced apically, exposing the root surface. This condition may be associated with esthetic concerns, dentin hypersensitivity, and difficulties in oral…
- Trial name
- VCMX-SCTG (NCT07613775)
- Testing
- Volume-stable xenogeneic collagen matrix (VCMX), Subepithelial connective tissue graft (SCTG)
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Gingival Diseases
Brief Title: a Clinical Study to Assess Gingivitis
The objective of this learning clinical study is to evaluate the effects of formulation chemistry on gingivitis.
- Trial name
- NCT06659471
- Testing
- 0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Procter and Gamble
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