Clinical trials: Gingival Condition
Healthy
Can Saliva be the New Bio-fluid to Monitor Children's Oral Health?
Background: Salivary diagnosis is an emerging field; the potentially valuable biofluid contains many molecules of the systemic circulation. Still, its profile in health has been scarcely investigated.
- Trial name
- NCT05495373
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Periodontal Diseases
The Role of Smoking in Periodontal Status
484 patients were asked whether they currently smoked and whether they had smoked 100 or more cigarettes during their lifetime. Based on this information, they were divided into two groups: current smokers (test group, n=242) and…
- Trial name
- TRSPS (NCT07295756)
- Testing
- Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Tuğba ŞAHİN
Connective Tissue, Gingiva
Comparison of Free Gingival Graft and Linear Incision for Connective Tissue
A randomized controlled non-inferiority trial will be conducted with 24 individuals aged 18 or older, who are periodontally healthy and require root coverage in bilateral multiple RT1-type recessions involving at least two teeth…
- Conditions
- Connective Tissue, Gingiva, Gingival Recession, Humans
- Trial name
- NCT06365983
- Testing
- Connective Tissue with Free Gingival Graft, Connective Tissue with Linear Incision
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
HİDRADENİTİS SUPPURATİVA
Periodontal Status and Disease Severity in Hidradenitis Suppurativa Patients
This cross-sectional study aims to evaluate the periodontal status of individuals diagnosed with hidradenitis suppurativa (HS) and to compare them with systemically healthy controls.
- Trial name
- NCT07294456
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Gingivitis, Periodontitis
Oral Health Care in Stroke Patients in Tertiary Care Hospital
To investigate oral care provision in stroke care settings in Pakistan. Stroke can have adverse effects on oral care and health. Little is known about current oral care practices in stroke care settings.
- Conditions
- Gingivitis, Periodontitis, Dental Hygiene
- Trial name
- NCT05114681
- Testing
- Assessment of Oral care as per patient personal choice
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Gingivitis
Comparisons Of Different Antiplaque Agents On Gingivitis In Orthodontic Patients
Fixed orthodontic treatment affects the periodontium by allowing plaque accumulation on teeth if the oral ecosystem is unfavorable which initially causes gingivitis to progress into periodontitis, and later enamel…
- Trial name
- NCT06305546
- Testing
- Chlorhexidine Gluconate, Metronidazole, combination gel (chlorhexidine and metronidazole)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Anam Sattar
Peri-implantitis, Dental Implant Complications
Analysis of the Factors Influencing the Occurrence of Peri-implant Inflammation in Patients With Oral Implant Repair and Study on the Maintenance Effect of Subgingival Sandblasting
Abstract Objective The purpose of this study was to analyze the factors affecting the occurrence of peri-implant inflammation in patients with oral implant repair, and to explore the effect of subgingival sandblasting technology…
- Conditions
- Peri-implantitis, Dental Implant Complications, Periodontal Inflammation, Gingival Diseases
- Trial name
- NCT06998160
- Testing
- glycine subgingival sandblasting group and erythritol subgingival sandblasting group, control group
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Hui Xie
Plaque, Dental, Gingivitis
Investigation of Colgate Dual Zinc Toothpaste as Compared to Colgate Cavity Protection Toothpaste in Controlling Plaque and Gingivitis
Qualified subjects will be enrolled and randomized to either one of the two study groups described above based on their initial Plaque and Gingivitis scores.
- Trial name
- NCT06430060
- Testing
- zinc containing toothpaste, MFP Fluoride toothpaste
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Health
A Model-based Health Education Program to Improve Oral Health in School Going Children
This was a randomized controlled trial to assess how an education program based on health belief model (HBM) may affect oral health status in the elementary school going children.
- Trial name
- NCT05112224
- Testing
- Education program based on health belief model to improve oral health
- Where
- Iran
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Baqiyatallah Medical Sciences University
Gingival Cleft, Orthodontic Space Closure
Gingival Cleft Development at Two Time Points of Canine Retraction
The goal of this split-mouth randomized controlled trial is to assess whether the timing of extraction space closure-early vs. delayed initiation-affects the incidence of gingival cleft development in orthodontic patients.
- Trial name
- NCT07210762
- Testing
- Early space closure, Delayed space closure
- Where
- Pakistan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bahria University
Periodontal Diseases, Smoking
The Effect of Scaling and Root Planing on Oral Inflammatory Biomarkers Among E-cig Users and Non-smokers
Background/Aim: There are no studies that have compared the gingival crevicular fluid (GCF) levels of IL-1β in non-smokers (NS) and electronic nicotine delivery system (ENDS)-users before and after scaling and root planing (SRP)…
- Trial name
- ENDS-SRP (NCT05745324)
- Testing
- Scaling and root planing
- Where
- Kuwait
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Gum Disease, Diabetes
Effectiveness of Personalized Oral Hygiene Advice Delivered by Artificial Intelligence or Dental Professionals Versus Standard Oral Hygiene Advice on Oral and Systemic Health in Community-based Type II Diabetes Patients
Diabetes is a systemic condition characterized by elevated blood glucose levels and is associated with multiple long-term complications.
- Trial name
- NCT07841717
- Testing
- AI OHI group, Human-OHI group, Control group
- Volunteers
- 105 people
- Sponsor
- The University of Hong Kong
Gingiva Disorder
Gingival Pigmentation Intensity and Distribution Among Egyptians
The aim of the present study is to evaluate the distribution, intensity and extension of gingival hyperpigmentation among a sample of Egyptian population.
- Trial name
- NCT07316205
- Testing
- Evaluatation of the gingival pigmentation intensty and distribution
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gingival Recession
Efficacy of Methods to Treat Multiple Gingival Recession Defects
Rationale: Treatment of gingival recession defects requires coronal advancement of the gingival margin due to patient esthetic demand, tooth sensitivity and improvement of tooth prognosis, which can be accomplished either through…
- Trial name
- NCT03124329
- Testing
- Coronally Advanced Flap, Intrasulcular Tunneling, Vestibular Incision Subperiosteal Tunnel Access (VISTA)
- Where
- United States
- Sponsor
- University of Southern California
Periodontitis
Apoptic Biomarkers of Periodontal Disease
The goal of this study is to facilitate early diagnosis of gum disease. Proteins associated with cell death will be isolated from gum pockets of diseased and healthy patients and evaluated.
- Trial name
- NCT00569075
- Testing
- collection of gingival crevicular fluid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hyaluronic Acid, Open Flap Debridement
Adjunctive 0.8% Hyaluronic Acid Gel in Open-Flap Surgery for Thin Gingival Phenotype in Patients With Periodontitis
The aim of this study is to evaluate the clinical effectiveness of 0.8% hyaluronic acid (HA) gel as an adjunct to open flap debridement (OFD) in periodontitis patients with a thin gingival phenotype.
- Conditions
- Hyaluronic Acid, Open Flap Debridement, Periodontitis, Gingival Phenotype
- Trial name
- NCT07130266
- Testing
- Procedure/Surgery: Hyaluronic acid gel application, giving an impression of the application
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Bezmialem Vakif University
PONV
Chewing Gum to Prevent Nausea and Vomiting After Caesarean Section Under Spinal Anaesthesia
Our study aims to determine if there is a difference in a self-reported incidence of nausea and vomiting in women who are given chewing gum following elective caesarean section under spinal anaesthesia compared to those who do…
- Trial name
- NCT04191694
- Testing
- Chewing Gum, Ondansetron 4 MG
- Where
- Ireland
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Coombe Women and Infants University Hospital
Dental Caries, Gingivitis
Oral Hygiene Intervention Pilot Study
The main goals of this pilot study are to develop a nursing home-customized oral hygiene protocol, intended to be delivered primarily by dental hygienists and primary care providers, and to identify potential obstacles and…
- Trial name
- NCT02668809
- Testing
- oral health assessment, Questionnaires, Clinical Exam
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Leonardo Marchini
Gingival Recession
Morbidity and Coverage Outcome With Connective Tissue Graft Used With Coronally Advanced Flap and Tunneling Technique
The aim of this randomized-controlled clinical trial is to compare the patient morbidity and root coverage outcomes of a sub-epithelial connective tissue (SeCTG) used in combination with a coronally advanced flap (CAF) and tunnel…
- Trial name
- NCT02269748
- Testing
- Tunnel technique with subepithelial connective tissue, Coronally advanced flap, Analgesic Therapy
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Periodontal Diseases
Evaluation and Comparison of Efficacy of PeriActive Mouthwash to Chlorhexidine 0.12% Mouth Rinse
Izun Pharmaceuticals has shown that PeriActive, an oral rinse containing extracts of Sambucus nigra, Echinacea purpurea, and Centella asiatica significantly reduced gingival inflammation in an experimental gingivitis model in a…
- Trial name
- NCT02987634
- Testing
- PeriActive
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Izun Pharma Ltd
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