Clinical trials: Gingival Condition
Gingivitis, Periodontitis
Galectin Role in Periodontal Disease
This study aimed at exploring the effect of nonsurgical periodontal treatment on galectin 1 and 3 GCF levels in patients having gingivitis, periodontitis stage III compared to periodontally healthy individuals and if galectin-1…
- Trial name
- NCT06038812
- Testing
- GCF sample collection, non-surgical periodontal treatment
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Gingivitis
To Compare the Effectiveness of Three Self-care Oral Hygiene Regimens
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04804670
- Testing
- Power device A, Power device B, Routine Oral Hygiene
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Gingival Recession, Localized
Effect of Vestibular Depth on Predictability of Miller Class III/ RT2 Gingival Recession Coverage
Aim of this study is to assess the influence of vestibular depth on root coverage in Miller class III/ Cairo RT2 gingival recession when treated with minimally invasive technique using connective tissue graft.
- Trial name
- NCT06000228
- Testing
- Recession coverage with CTG using minimally invasive access technique in shallow vestibule, Recession coverage with CTG using minimally invasive access technique in deep vestibule
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Health, Crowding of Anterior Mandibular Teeth
To Compare the Effects of Lip Bumper Appliance in Rate of Lower Incisor Alignment After First Premolar Extractions
The goal of this clinical trial is to check the effects of lip bumper appliance contribution to driftodontics after designated tooth extractions that are already part of orthodontic treatment plan.
- Trial name
- NCT06929754
- Testing
- Lip bumper
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bahria University
Gum Disease
Periodontal Treatment and Psychology
There is a relationship between depression and periodontal disease. This relationship may be double-sided. A psychological state such as anxiety, depression, body image, and self-esteem may be affected from the symptoms of…
- Trial name
- NCT03190512
- Testing
- Psychological measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people
- Sponsor
- Ozge Gokturk
Gingivitis, Gingivitis; Chronic
A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental Students
This multicentre randomised controlled trial aims to evaluate the efficacy and safety of the SMILETM (Siwak Method for Integrated Lifestyle Enhancement) module in improving short-term periodontal outcomes, oral hygiene behaviour…
- Trial name
- SMILE (NCT07702383)
- Testing
- SMILE Module, Conventional Toothbrushing Module
- Where
- 4 sites in Malaysia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Peridontal Disease, Periodontal Inflammation
Analysis of the Impact of Contemporary Subgingival Debridement Techniques on Immunological Biomarkers in Gingival Crevicular Fluid
AIM: This prospective clinical study aimed to evaluate the efficacy of two distinct non-surgical periodontal therapy modalities in patients diagnosed with Stage 1 and Stage 2 periodontitis.
- Conditions
- Peridontal Disease, Periodontal Inflammation, Periodontitis, Adult
- Trial name
- NCT07243145
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcen Ozcan Bulut
Caries, Erosive Tooth Wear
New In Situ Model Design for Caries and Erosion
This study will test simultaneously and independently two novel in situ models, one for caries and one for erosive tooth wear (ETW), based on the simulation of these dental conditions on enamel specimens placed on 3D-printed…
- Trial name
- NCT07849270
- Testing
- 0 ppm fluoride toothpaste, 250 ppm fluoride toothpaste (dose-response control), 1150 ppm fluoride toothpaste
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Indiana University
Xerostomia
Comparison of Gum® HydralTM Moisturizing Gel and Biotene® Oral Gel in Dry Mouth Sensation Reduction
Background. Xerostomia is estimated to affect up to 50% of the adult population and especially the elderly suffer from dry mouth sensation.
- Trial name
- NCT05342272
- Testing
- Betaine taurine PVP gel, Xylitol, Lactoperoxidase, Lysozyme, Lactoferrin
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Periodontal Diseases
Comparison of the Effectiveness of the USG and CBCT Combined With Intraoral Scanning Determing the Gingival Phenotype in the Healthy Periodontium
Compare two diagnostic methods: UGTM and CBCT/CAD/PDIP in determing the gingival phenotype in group of 30 periodontally healthy patients.
- Trial name
- NCT04845581
- Testing
- Diagnostic tests: Determination of the gingival phenotype, measure gingival thickness and width of keratinized tissue
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Localized Gingival Enlargement, Epulides
Periodontal Plastic Reconstruction of Soft Tissue Dehiscences After the Removal of Localized Gingival Enlargements
Non-inflammatory recessions and Miller class I-II-III. mucogingival defects after elimination of localized gingival enlargements are frequently encountered challenges in the daily practice. In Miller class II-III.
- Conditions
- Localized Gingival Enlargement, Epulides, Recurrence, Periodontal; Lesion
- Trial name
- NCT06210789
- Testing
- Surgical excision
- Where
- Hungary
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Alveolar Bone Loss, Alveolar Ridge Pathology | Gingiva | Dental
Comparative Study of Gene-activated Bone Substitute and Xenogenic Bone Matrix in Alveolar Ridge Augmentation
The study aim is to compare the effectiveness of two bone substitutes, the gene-activated bone substitute based on octacalcium phosphate and plasmid DNA encoding VEGFA gene and xemogenic deproteinized bone matrix, mixed with…
- Trial name
- NCT04511689
- Testing
- gene-activated bone substitute mixed with autobone
- Where
- Russia
- Volunteers
- 24 people
- Sponsor
- Histograft Co., Ltd.
Gingivitis, Periodontitis
Clinical Examination of Metal Free Interdental Brushes
The aim of the study was to evaluate the clinical efficacy (Eastman Interdental Bleeding Index, Quigley and Hein) of a novel metal-free interdentalbrush compared to a classig metal-core interdental brush.
- Trial name
- NCT01593540
- Testing
- metal-free interdental brush, metal-core interdental brush
- Where
- Germany
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Freiburg
Gingivitis
An Efficacy Study of Chlorhexidine Mouthwashes
The aim of this study is to compare subject gingival health after 6 weeks of twice daily use of a non-alcohol or alcohol containing mouthrinse and brushing compared to brushing only.
- Trial name
- NCT01751178
- Testing
- Chlorhexidine Digluconate Mouthwash with Alcohol, Chlorhexidine Digluconate Mouthwash without Alcohol
- Where
- 3 sites in United Kingdom
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingival Recession
Evaluation of De-epithelized Connective Tissue Grafts and Modified Combined Approach for Connective Tissue Grafts
This study aims to compare the de-epithelized gingival graft (control group) and modified combined approach for connective tissue graft (test group) in patients undergoing palatal graft harvesting for mucogingival surgery in the…
- Trial name
- NCT05717985
- Testing
- modified combined approach, de-epithelized gingival graft
- Where
- Malaysia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Periodontal Diseases
Osteocalcin Level in Gingival Clavicular Fluid During Canine Retraction in Periodontal Compromised Patients
Osteocalcin levels can be measured Gingival crevicular fluid (GCF). Changes in osteocalcin levels can provide important information about the status of bone metabolism and bone remodeling.
- Trial name
- NCT06102616
- Testing
- measure Osteocalcin level
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Faculty of Dental Medicine for Girls
Good Health, Gingival Inflammation and Bleeding
Oil Pulling Reduction
The goal of this study is to scientifically evaluate the efficacy of this oil pulling oral rinse in reducing dental plaque, gingival inflammation, gingival bleeding, and selectively reducing caries- and periodontal…
- Conditions
- Good Health, Gingival Inflammation and Bleeding, Dental Plaque
- Trial name
- NCT07706647
- Testing
- GuruNanda natural Oil Pulling oral rinse, TheraBreath Plaque Control Oral Rinse, GuruNanda water-based non-whitening mouthwash
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Gingivitis
Clinical Investigation of PerioGard (Test) Regimen
The objective of this three-month clinical research study is to evaluate the clinical efficacy of the PerioGard (test) regimen (0.45% SnF-HW Toothpaste, CPC-Zinc-Fluoride Mouthwash, Gummy Toothbrush) compared to the control…
- Trial name
- NCT07210138
- Testing
- PeriGuard regimen, Colgate Dental Cream regimen
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Adolescent Behavior, Dental Plaque
Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)
This is a Phase III, randomized, one-center, three arm parallel group, open label and single blind clinical study to evaluate the effectiveness of a cognitive behavioral intervention (CBI) adjunctive to a smart powered toothbrush…
- Conditions
- Adolescent Behavior, Dental Plaque, Gingivitis, Cognitive Change
- Trial name
- NCT05782348
- Testing
- Cognitive behavioral intervention, Colgate smart toothbrush
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Howard University
Gingival Recession
Comparison of Cyanoacrylate Tissue Adhesive With Suture in the Treatment of Gingival Recession
The aim of this randomized controlled clinical study was to determine the effects of gingival recession closure procedures performed with tissue adhesive and suture on gingival thickness, To evaluate the effect on the amount of…
- Trial name
- NCT06499155
- Testing
- Use of periacryl in gingival recession closure procedures, Use of sutures in gingival recession closure procedures
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.