Clinical trials: Gingival Condition
Gingival Recession, Tooth Abrasion
A New Surgical-restorative Approach to Treat Gingival Recessions Associated With Non-carious Cervical Lesions (NCCL)
The aim of the present study is to evaluate the clinical, aesthetic and patient-centered parameters of connective tissue graft associated or not with partial resin composite (RC) for the treatment of gingival recession with NCCL…
- Trial name
- NCT02817763
- Testing
- Connective tissue graft (CTG), CTG plus resin composite restoration, sodium dipyrone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Oral Hygiene, White Spot Lesion
Effects of Active Reminders and Motivational Techniques on Oral Hygiene and Gingival Health in Orthodontic Patients
This study will compare the use of text message reminders versus multiple in-person sessions of oral hygiene instructions and motivation on improving oral hygiene measurements.
- Conditions
- Oral Hygiene, White Spot Lesion, Gingivitis
- Trial name
- NCT03841825
- Testing
- Oral hygiene instructions
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Gingivitis, Orthodontic Appliance Complication
Influence of Probiotics on Clinical Parameters, the Oral Microbiome and the Immune System During an Orthodontic Treatment
Orthodontic treatment with fixed appliances can be necessary to correct malocclusions in adolescence or adulthood. It its known that orthodontic treatment induces aseptic pseudo-inflammatory reactions.
- Trial name
- NCT04598633
- Testing
- Lactobacillus reuteri Prodentis®-lozenges (DSM 17938, ATCC PTA 5289)
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Dental Implants, Single-Tooth
The Effect of Different Shapes of Interdental Brushes in the Management of Peri-implant Mucositis and Gingivitis
Rehabilitation of edentulous spaces with dental implants has become a routine treatment option as implants enjoy high survival rates over time.
- Trial name
- NCT03575858
- Testing
- Barrel shaped interdental brush, Tapered interdental brush
- Sponsor
- National University Health System, Singapore
Periodontal Diseases
Accuracy of Assessing the Gingival Biotype in Upper Anterior in Adult Patients, Using Different Methods.
The study is a Diagnostic accuracy study that determining the accuracy of assessing the gingival biotype and some other anatomic parameters,including (crown width / crown length ratio, attached gingival width, labial bone…
- Trial name
- NCT04640506
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Pocket
The Proposed Study Aims to Investigate the Impact of Adjunctive Vitamin D Gel Application on Gingival Crevicular Fluid Levels of Alkaline Phosphatase and Interleukin-8 in Periodontitis Patients Undergoing Phase 1 Periodontal Therapy. By Elucidating the Molecular Mechanisms Underlying the Therapeutic
The proposed study aims to investigate the impact of adjunctive vitamin D gel application on gingival crevicular fluid levels of alkaline phosphatase and interleukin-8 in periodontitis patients undergoing phase 1 periodontal…
- Trial name
- NCT06669026
- Testing
- vitamin D loaded Poly lactic-co-glycolic acid nanoparticles gel, vitamin D3 gel (regular non-nanoparticle form), only mechanical debridement
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Plaque, Gingivitis
The Study to Evaluate the Plaque Control and Anti-Gingivitis Efficacy of a Toothpaste in Chinese Population
The aim of this study is to evaluate the efficacy of the test toothpaste compared to a regular fluoride toothpaste in the reducing gingivitis and plaque accumulation in Chinese participants with plaque-induced gingivitis.
- Trial name
- NCT07816406
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- HALEON
Microbiome, Cytokines
Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis
This study is a six-week, double-blind, randomized, parallel-group controlled clinical study. The objective of this study is to evaluate the changes to the oral microbiome, inflammatory mediators, gingival health indices and to…
- Conditions
- Microbiome, Cytokines, Plaque, Gingivitis
- Trial name
- NCT07501455
- Testing
- Distilled Water, Marketed Comparator 1, Marketed Comparator 2
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Gingival Inflammation, Dental Caries
Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences
Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's…
- Trial name
- NCT07124533
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Periodontal Diseases, Gingivitis
Effect of Periodontal Treatment on Inflammasome Proteins in Periodontal Diseases
The present study aimed to assess the effect of non-surgical periodontal treatment on serum and salivary IL-1beta, IL-18, NLRP3, ASC and Caspase-1 levels in gingivitis and Stage III Grade C periodontitis.
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis
- Trial name
- NCT06075680
- Testing
- Non-Surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
Periodontal Diseases, Obesity, Morbid
Gingival Crevicular Fluid of Adiponectin and Resistin As Predictable Implement in Staging and Grading System of Periodontitis
The goal of this clinical trial is to evaluate the relationship between obesity and gingival crevicular fluid resistin and adiponectin in periodontitis patients as well as assess the effect of non-surgical periodontal therapy on…
- Trial name
- NCT06604013
- Testing
- non-surgical full-mouth periodontal therapy without using adjunct disinfectants, GCF level of adiponectin and resistin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Tobacco Dependence
Pharmacokinetics With Two New Oral Nicotine Replacement Products and Nicorette® Gum
Single-dose pharmacokinetics with two new oral nicotine replacement products and Nicorette® gum.
- Trial name
- NCT01152723
- Testing
- Nicotine
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- McNeil AB
Gingival Recession
Single Stage Root Coverage for Gingival Recession With or Without Free Gingival Graft
Background and Objective: Gingival recession accounts for apical migration of the gingival margin resulting in exposure of the cementoenamel junction (CEJ) and root surface.
- Trial name
- NCT03370042
- Testing
- semilunar coronally positioned flap with free gingival graft, semilunar coronally positioned flap alone
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kamineni Institute of Dental Sciences
Palatal Wound
Effect of Low-level Laser Therapy on Palatal Wound Healing
The aim of the present study was to evaluate the influence of LLLT on the recovery of the palatine donor site wounds after harvest connective tissue graft.
- Trial name
- LLLT (NCT02239042)
- Testing
- LLLT
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Gingival Recession
Gingival Augmentation and Root Coverage With Superficial and Deep Cut Acellular Dermal Matrices
This entire protocol involves procedures that are standard care and will randomize subjects to of one two routine care procedures. Patients needing root coverage for gingival recession will be enrolled.
- Trial name
- NCT05956496
- Testing
- Allograft Material ADM-S, Allograft Material ADM-D
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Healthy, Overweight
Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose, Insulin Levels and Food Intake
Study to evaluate the effect of gum acacia (FibregumTM) on post-prandial glucose and insulin levels and food intake in normal-weight and overweight subjects during a 2-7 weeks intervention period.
- Trial name
- NCT04515277
- Testing
- 40 g Gum acacia (FibregumTM), 20 g Gum acacia (FibregumTM), 0 g Gum acacia (FibregumTM)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nexira
Gingival Recession, Localized
Microsurgical vs Macro Surgical Approach for Grade II Gingival Recessions Employing Laterally Repositioned Flap
This study was conducted to assess the evaluation of micro and Macro surgical approach in the treatment of grade II gingival recessions using the laterally repositioned flap
- Trial name
- CCMMRCLDF (NCT03654339)
- Testing
- root coverage
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Gynecologic Nursing, Pain
The Effect of Chewing Gum and Hot Compresses on Gynecologic Oncologic Surgery
The passage discusses the recovery of gastrointestinal (GI) function after abdominal surgery and the potential impact on patient comfort.
- Trial name
- NCT06196138
- Testing
- Gum, Hot Compress
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Gingivitis
Effectiveness of Metronidazole Gel and Mobile SMS Reminders on Gingivitis in Orthodontic Patients
A rapid deterioration in oral hygiene occur after bonding of orthodontic appliances. Zachrisson and Zachrisson have reported that even after maintaining excellent oral hygiene, patients usually experience mild to moderate…
- Trial name
- NCT03508999
- Testing
- Metronidazole gel, SMS text reminder
- Where
- Pakistan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Periodontal Diseases, Inflammation Gum
Evaluation of Oral Condition and the Effect of Dental Treatment on Physical Parameters of Athletes
It is essential that athletes have perfect general health. Oral health plays an important role in this healthy framework necessary so that the results that must be achieved by athletes are not influenced.
- Conditions
- Periodontal Diseases, Inflammation Gum, Caries,Dental
- Trial name
- NCT04251858
- Testing
- Dental Scaling, Oral hygiene instruction
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Metropolitana de Santos
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