Clinical trials: Gingival Condition
Gingival Recession
PRF for Accelerating Palatal Healing
Backgroung: Various agents are used to reduce post-operative complications associated with palatal donor site surgery for free gingival graft (FGG) harvesting.
- Trial name
- NCT02712242
- Testing
- Platelet Rich Fibrin, Butyl cyanoacrylate, Wet gauze
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Bone Loss, Implant Complication
The Effects of Dis/Reconnection of Implant Abutments on Peri-implant Bone Levels
The aim of this study was to evaluate the effects of definitive abutment connection at the time of implant placement on peri-implant bone levels and soft tissue changes in posterior maxilla and mandible regions.
- Conditions
- Bone Loss, Implant Complication, Gingival Recession
- Trial name
- NCT04043286
- Testing
- Definitive abutment
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Gingival Inflammation and Loss the Orthodontic Mini-screws
Strontium-Hydroxyapatite Coated Mini-Screws: Antibacterial Effect and Stability
This randomized controlled clinical trial aims to evaluate the antibacterial efficacy and stability of strontium-incorporated hydroxyapatite (Sr-HA) coated orthodontic mini-screws (OMSs) used for maxillary canine retraction.
- Trial name
- NCT07105969
- Testing
- Strontium Incorporated Hydroxyapatite [Sr-HA] coated mini-screws purchased from Dentarum company
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Recession, Gingival, Surgical Procedure, Unspecified
Alternative Gingival De-Epithelialization Techniques
The goal of this clinical trial is to compare different de-epithelialization methods in patients undergoing soft tissue augmentation surgery.
- Conditions
- Recession, Gingival, Surgical Procedure, Unspecified, Graft Complication, Wound Heal
- Trial name
- NCT05947305
- Testing
- Surgical Blade, Mucotome, Diamond Bur
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Plaque Induced Gingivitis, Mouth Diseases
Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years Old
The goal of this clinical trial is to test the efficiency of using lozenges containing propolis extract over one week to control gingival inflammation and plaque accumulation by measuring the clinical periodontal parameters…
- Conditions
- Plaque Induced Gingivitis, Mouth Diseases, Periodontal Diseases
- Trial name
- NCT06888453
- Testing
- lozenges containing propolis
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Periodontitis, Gingivitis
Effect of Non-Surgical Periodontal Treatment on Gingival Crevicular Fluid and Serum Biomarker Levels
Periodontal diseases are one of the most common inflammatory diseases. Periodontitis results from products and antigens of microorganisms, which stimulates the innate immune system and local inflammatory response; characterized…
- Conditions
- Periodontitis, Gingivitis, Healthy
- Trial name
- NCT06175624
- Testing
- Clinically Helathy, Gingivitis, Periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Biruni University
Gingival Recessions
m-VISTA Technique vs. CAF in the Treatment of Class III Multiple Recessions
The main objective is to assess whether the percentage of root coverage (%RC) achieved in the treatment of multiples class III recessions using the technique we have called modified vestibular incision subperiosteal tunnel access…
- Trial name
- NCT03258996
- Testing
- Modified vestibular incision subperiosteal tunnel access, Coronally advanced flap
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aitziber Fernandez Jimenez
Periodontitis, Adult
Fetuin A Association in Periodontal Disease and Diabetes Mellitus
Aim: The aim of the current study was to compare and correlate gingival crevicular fluid (GCF) fetuin-A levels and high sensitivity C-reactive protein (hs-CRP) levels in non-diabetic periodontitis patients and type 2 diabetic…
- Trial name
- NCT06064786
- Testing
- GCF levels of fetuin A and hsCRP evaluation
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Horton Disease
Chewing Gum Test for the Diagnosis of Giant Cell Arteritis (Horton's Disease) - ChewingHort
It is hypothesized that chewing-gums may be a useful test to unmask jaws intermittent claudication in order to enhance the diagnosis of Giant Cell Arteritis (GCA).
- Trial name
- ChewingHort (NCT04010097)
- Testing
- chewing gum
- Where
- 6 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Gingiviits
Comparion of Effects of Two Different Power Toothbrushes on Plaque and Gum Health
The goal of this clinical trial is to learn if powered toothbrushing with a side-to-side motion is more effective than powered toothbrushing with oscillating-rotation motion in removing dental plaque.
- Trial name
- NCT07813546
- Testing
- oscillating-rotating powered toothbrush, side-to-side powered toothbrush
- Where
- United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Lack of Keratinized Tissue, Mucogingival Surgery
Evaluation of the Effects of Injectable Platelet-Rich Fibrin and Hyaluronic Acid Treatments, Administered in Addition to Free Gingival Graft Therapy, on Clinical Healing.
The purpose of this clinical trial is to evaluate the effects of injectable platelet-rich fibrin (i-PRF) and hyaluronic acid (HA) gel on clinical healing and graft shrinkage when used in addition to Free Gingival Graft (FGG)…
- Conditions
- Lack of Keratinized Tissue, Mucogingival Surgery, Gingival Recession
- Trial name
- IPRF-HA-FGG (NCT07804888)
- Testing
- Free gingival graft, Free Gingival Graft with i-PRF, Free Gingival Graft with Hyaluronic Acid
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Saglik Bilimleri Universitesi
Tooth Sensitivity
Efficacy of Azadirachta Indica Based Herbal Mouthwash in Treating the Tooth Hypersensitivity
Type of study: Single-blinded clinical trial to evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat the tooth sensitivity in patients.
- Trial name
- NCT06288776
- Testing
- Herbal based mouthwash
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Plaque and Gingivitis
The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis
This is a six (6) month, double-blind, parallel, controlled clinical trial utilizing one hundred and sixty (160) adults to evaluate the reduction of dental plaque and gingivitis.
- Trial name
- NCT02243046
- Testing
- Control toothpaste, Experimental toothpaste, Active Comparator
- Where
- Dominican Republic
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Bowel Ileus, Cesarean Section Complications
Effect of Chewing Gum and Drinking Fennel Tea
Aim: Postoperative ileus after cesarean section is a problem that significantly prolongs hospital stay and increases perioperative costs.
- Trial name
- NCT06403215
- Testing
- Chewing gum group, Fennel tea group, Chewing gum+Fennel tea group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Dental Plaque, Gingivitis
Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
The objective of this clinical research study is to assess the efficacy of a commercially available triclosan/copolymer toothpaste compared to a commercially available oral hygiene multi-component regimen encompassing the use of…
- Trial name
- NCT02366689
- Testing
- Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Gingivitis and Periodontal Diseases
Investigating the Periodontal Status of Traditional and Heated Tobacco Product Users
This cross-sectional observational study aims to compare the clinical and radiographic periodontal status, as well as gingival crevicular fluid volume, among cigarette smokers, heated-tobacco product users, and non-smokers.
- Trial name
- INPER-THT (NCT06784817)
- Where
- Hungary
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Plaque, Gingivitis
Clinical Evaluation of the Efficacy of a Marketed Dentifrice on Plaque and Gingivitis
Parallel, double blind, randomized, Institutional Review Board (IRB) -approved study involving approximately 160 subjects to complete.
- Trial name
- NCT03214406
- Testing
- Arm & Hammer Advance White Brilliant Sparkle (Test product), Crest Cavity Protection Regular Toothpaste (Negative Control)
- Where
- Canada
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Gingivitis
Assessment of the Efficacy and Safety of OROXID® Oral Solution in Patients With Gingivitis
Gingivitis is a reversible inflammation of the gums caused by the accumulation of dental plaque. Without appropriate intervention-such as proper oral hygiene and plaque removal-gingivitis can progress to periodontitis, leading to…
- Trial name
- OroxGing (NCT07270705)
- Testing
- OROXID® forte oral solution, OROXID® sensitive oral solution, Standard of Care
- Where
- 2 sites in Slovenia
- Volunteers
- 90 people
- Sponsor
- ENIKAM d.o.o.
Gingival Recession
Efficacy of a Modified Technique of Free Gingival Graft in Volumetric Changes of the Graft: Randomized Clinical Trial
This study will compare a new technique of free gingival graft to the original one, in order to evaluate the stability of the graft volume over one year and other variables.
- Trial name
- EFFECT (NCT02613702)
- Testing
- Free Gingival Graft, Original Free Gingival Graft technique, Modified Free Gingival Graft technique
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
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