Clinical trials: Gingival Condition
Gingival Recession
Clinical Evaluation of Two Different Surgical Techniques With PRF in the Treatment of Multiple Gingival Recessions
This prospective clinical study aims to evaluate and compare the effectiveness of coronally advanced flap (CAF) and tunnel techniques, both combined with platelet-rich fibrin (PRF), in the treatment of multiple Miller Class I-II…
- Trial name
- NCT06986525
- Testing
- CAF with PRF, Tunnel with PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Frenulum; Hypertrophy, Diode Laser
Diode Laser Versus Conventional Frenectomy in Children
This prospective, randomized, open-label, parallel-group clinical trial aims to compare diode laser frenectomy with conventional scalpel frenectomy in children aged 8-12 years with a clinical indication for maxillary labial…
- Conditions
- Frenulum; Hypertrophy, Diode Laser, Frenectomy, RT-PCR
- Trial name
- NCT07853599
- Testing
- Diode Laser Frenectomy, Conventional Scalpel Frenectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Yuzuncu Yil University
Periodontitis
Netrin 1 and Its Receptor Unc5b as Markers of Periodontal Disease
This study aimed to investigate gingival crevicular fluid (GCF), saliva and serum Netrin 1 and Unc5b levels in periodontal health and disease.
- Trial name
- NCT03919006
- Testing
- non surgical periodontal treatment, Gingival crevicular fluid, saliva and serum collection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingival Recession, Tooth Abrasion
A New Surgical-restorative Approach to Treat Gingival Recessions Associated With Non-carious Cervical Lesions (NCCL)
The aim of the present study is to evaluate the clinical, aesthetic and patient-centered parameters of connective tissue graft associated or not with partial resin composite (RC) for the treatment of gingival recession with NCCL…
- Trial name
- NCT02817763
- Testing
- Connective tissue graft (CTG), CTG plus resin composite restoration, sodium dipyrone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Patient Satisfaction, Bleaching Efficacy
Patient Satisfaction With At-home Dental Bleaching Using Orthodontic Retainers With Different Margin Designs
This randomized single-blind, split-mouth clinical trial evaluated patient satisfaction with at-home dental bleaching using orthodontic retainers with different margin designs, as well as bleaching efficacy, tooth sensitivity…
- Conditions
- Patient Satisfaction, Bleaching Efficacy, Tooth Sensitivity, Gingival Irritation
- Trial name
- NCT07208708
- Testing
- Scalloped margin retainer, Straight orthodontic retainer
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Rey Juan Carlos
Behavior, Periodontal Diseases
Global Behavior and Periodontal Disease in Down's Syndrome Patients
This study aimed at correlating global behavior of Down's Syndrome patients to periodontal disease status.
- Trial name
- NCT02941887
- Testing
- Behavior Analysis
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- University of Sao Paulo
Plaque-Induced Gingivitis
Impact of Oral Hygiene Instruction in Gingivitis Patients
The aim of this study is to comparatively evaluate the effectiveness of two different oral hygiene instruction methods given in addition to Phase 1 periodontal treatment in patients diagnosed with gingivitis, on periodontal…
- Trial name
- NCT07479706
- Testing
- video-based oral hygiene instruction, Model-based oral hygiene instruction
- Where
- Turkey (Türkiye)
- Sponsor
- Ankara University
Gingival Recession, Generalized
Clinical, Patient-centered Outcomes and Laser Doppler Flowmetry Using Two Types of SCTG
This split-mouth randomized clinical trial compared two different types of subepithelial connective tissue grafts (SCTG) considering clinical parameters and patient-centered outcomes in patients with bilateral RT 1 multiple…
- Trial name
- NCT04093674
- Testing
- de-epithelized (DE) SCTG
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Wound Healing, Pain
Effect of Cyanoacrylate and Concentrated Growth Factor on Palatal Donor Site
The aim of this planned randomized controlled clinical study is to evaluate the morbidity of the palatal donor area after free gingival graft (FGG) operations.
- Conditions
- Wound Healing, Pain, Patient Comfort
- Trial name
- NCT06459947
- Testing
- Free gingival graft procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Periodontal Diseases, Periodontitis
Interaction Between Immune Cells and Bacteria Associated With Periodontitis
This study evaluates the interaction between host immune cells and bacteria associated with periodontitis. It comprises biological material from donors with and without periodontal disease.
- Conditions
- Periodontal Diseases, Periodontitis, Aggressive Periodontitis, Immunologic Disease
- Trial name
- NCT03225950
- Testing
- In vitro stimulation of blood with periodontitis-associated- and control bacteria, Anti-CCP- and anti-P.g.-antibodies titers, Analysis of selected single nucleotide polymorphisms (SNPs)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periodontitis, Subgingival Plaque
The Effect of Post-surgical Chlorhexidine Mouth Washing on the Sub-gingival Periodontal Microbiome A Pilot Study
Prospective applicants who conform with inclusion and exclusion criteria will be accepted into the study and sign a consent form.
- Trial name
- SUPEM1 (NCT05355740)
- Testing
- Corsodyl
- Where
- 2 sites in Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Renal Insufficiency Chronic, Chronic Periodontitis
Effect on Teeth and Gum Cleaning in Patients With Gum and Kidney Disease
The main aim and objective of this study was to evaluate the effects of Non- surgical periodontal therapy on the subgingival microbiota and biochemical parameters in patients with chronic kidney disease and chronic periodontitis.
- Trial name
- ETGPGK (NCT02901743)
- Testing
- Scaling and Root planing
- Volunteers
- 40 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Peri-Implantitis, Peri-implant Mucositis
Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health
Cross-sectional study involving the measurement of the width of lingual keratinized tissue (in the implant locations) in fully edentulous patients restored with dental implants.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Recession, Gingival
- Trial name
- NCT06166017
- Testing
- Exposure to minimal amount of lingual keratinized tissue width
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- George Eastman Dental Hospital, Italy
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Coronary Syndrome, Periodontitis
Neutrophil Elastase, Elastase Alpha-1 Proteinase, Periodontitis, Gingival Crevicular Fluid and Acute Coronary Syndrome
Periodontitis may contribute to vascular damage, resulting in the destabilization of atherosclerotic plaque leading to acute coronary syndrome (ACS).
- Trial name
- NCT04785235
- Testing
- Non-Surgical Periodontal Therapy
- Volunteers
- 43 people
- Sponsor
- Baskent University
Caries, Gum Disease
Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, Mexico
Study aimed at evaluating the impact on oral health of the "Ley del Paquete de Salud Bucal" (daily school brushing program) combined, or not, with the application of fluoride varnish in schoolchildren from 6 to 8 years old who…
- Trial name
- DBMX (NCT05960110)
- Testing
- Fluoride varnish, Fluoride toothpaste
- Where
- Mexico
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Anahuac Mayab University
Gingival Recession, Tooth Abrasion
Mucoderm® Versus CTG in the Treatment of Multiple Gingival Recessions Associated With Non-carious Cervical Lesion.
The aim of the present study is to compare two different multidisciplinary protocols using two types of grafts, porcine acellular dermal matrix (Mucoderm®) versus connective tissue graft, both associated with modified coronally…
- Trial name
- NCT03594513
- Testing
- MCAF, PR, CTG
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Bleeding
Garlic With Lime Juice and Chlorhexidine Mouthwash
the study about herbal mouthwash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and their effect on gingival bleeding and plaque and salivary bacteria.
- Trial name
- mouthwash (NCT03105960)
- Testing
- garlic with lime mouth wash, chlorhexidine
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Hygiene, White Spot Lesion
Effects of Active Reminders and Motivational Techniques on Oral Hygiene and Gingival Health in Orthodontic Patients
This study will compare the use of text message reminders versus multiple in-person sessions of oral hygiene instructions and motivation on improving oral hygiene measurements.
- Conditions
- Oral Hygiene, White Spot Lesion, Gingivitis
- Trial name
- NCT03841825
- Testing
- Oral hygiene instructions
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Gingivitis
Efficacy of SALI-10 Oral Probiotics in Experimental Gingivitis
Gingivitis is among the most prevalent oral diseases worldwide, affecting an estimated 50-90% of adults. It is a reversible condition primarily caused by microbial plaque accumulation on teeth and gingival surfaces, which…
- Trial name
- NCT07256743
- Testing
- SALI-10 lozenge
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ostia Sciences
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