Clinical trials: Gingival Condition
Hyaluronic Acid, Open Flap Debridement
Adjunctive 0.8% Hyaluronic Acid Gel in Open-Flap Surgery for Thin Gingival Phenotype in Patients With Periodontitis
The aim of this study is to evaluate the clinical effectiveness of 0.8% hyaluronic acid (HA) gel as an adjunct to open flap debridement (OFD) in periodontitis patients with a thin gingival phenotype.
- Conditions
- Hyaluronic Acid, Open Flap Debridement, Periodontitis, Gingival Phenotype
- Trial name
- NCT07130266
- Testing
- Procedure/Surgery: Hyaluronic acid gel application, giving an impression of the application
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Bezmialem Vakif University
Peridontal Disease, Periodontal Inflammation
Analysis of the Impact of Contemporary Subgingival Debridement Techniques on Immunological Biomarkers in Gingival Crevicular Fluid
AIM: This prospective clinical study aimed to evaluate the efficacy of two distinct non-surgical periodontal therapy modalities in patients diagnosed with Stage 1 and Stage 2 periodontitis.
- Conditions
- Peridontal Disease, Periodontal Inflammation, Periodontitis, Adult
- Trial name
- NCT07243145
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcen Ozcan Bulut
Plaque Ph Lowering After Use of Probiotics, Caries
Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study
The aim of the present research protocol was to evaluate the effect of probiotics daily used, on the plaque acidogenicity of children.
- Conditions
- Plaque Ph Lowering After Use of Probiotics, Caries, Gingivitis
- Trial name
- NCT01601145
- Testing
- consumption of lozenges
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- Università degli Studi di Sassari
Dental Implantation, Missing Teeth
The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness
Scientists do research to answer important questions which might help change or improve the way we do things in the future. The investigators know that using Enamel Matrix Derivatives results in thicker gum tissues around teeth.
- Conditions
- Dental Implantation, Missing Teeth, Periodontitis, Adult, Mucositis
- Trial name
- NCT07053969
- Testing
- Enamel Matrix Derivative
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Gingival Pigmentation, Melanosis
Comparative Evaluation of Microsurgery vs Diode Laser Technique of Gingival Depigmentation
Gingiva being the most frequently pigmented tissue of the oral cavity challenges a lot of people with an esthetic concern. Increased production of melanin, a pigment produced by the melanocytes present in the basal and suprabasal…
- Trial name
- NCT05930366
- Testing
- Gingival depigmentation using microsurgery, Gingival Depigmentation using Diode Laser
- Where
- India
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingivitis
Dose-Response Study of Iocide Oral Rinse
The purpose of this study is to explore the dose-response relationship of Iocide oral rinse in a clinical trial of gingivitis. Approximately sixty (60) otherwise healthy subjects having gingivitis will be randomized into the…
- Trial name
- NCT01103102
- Testing
- Iocide Oral Rinse
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Biomedical Development Corporation
Obesity, Periodontal Diseases
Gingival Crevicular Fluid Levels of Prolactin Hormone in Obese Patients With Stage ii and Iii Periodontitis Before and After Non-surgical Periodontal Therapy
Obesity and periodontitis are among the most common chronic disorders affecting the world population, while Prolactin (PRL) is a neuroendocrine hormone that within the physiological range stimulates bone formation while mild to…
- Trial name
- NCT07571850
- Testing
- Obese patients with stage II and III periodontitis and non surgical peridontal therapy, obese patients with healthy periodontium with no intervention
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Gingival Recession, Lack of Keratinized Gingiva
The Effect of Free Gingival Graft on Root Closure
Free gingival graft is a mucogingival surgical technique applied to increase keratinized gingival width and reduce gingival recession.
- Trial name
- NCT05604391
- Testing
- Free gingival graft placed apically, Free gingival graft placed coronally
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Tooth Eruption Disorder
Digital Planning and Guided Dual Technique in Aesthetic Crown Lengthening
Excessive gingival exposure, commonly named gingival smile, results in a dentogingival disharmony. One of the gingival smile treatment is the aesthetics-related crown lengthening surgery (ACL) to provide a adequate clinical crown…
- Trial name
- NCT04922086
- Testing
- Conventional aesthetic crown lengthening surgery, Guided dual aesthetic crown lengthening surgery
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Alfenas
Gingival Recession
Evaluation of Two Types of Matrix (Mucograft® and Mucoderm®) Associated With Coronally Advanced Flap
The aim of this study is to evaluate clinically the results of two types of matrix (Geistlich Mucograft® and Mucoderm®) associated with CAF technique for the treatment of gingival recessions.
- Trial name
- NCT03667105
- Testing
- CAF, MC, XDM
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession
Gingival Recession and Oral Health-related Quality of Life: A Cross-sectional Study
Aim of this study is the assessment of gingival recession and its impact on oral health related quality of life in tertiary health care center in Haryana state. Objectives: 1.
- Trial name
- NCT07557277
- Testing
- Systemically healthy individuals 18-45 years of age, having gingival recession
- Where
- India
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis, Diabetes Mellitus
Effects of Gum Disease Treatment on Host Defense Factors
Human immune system produces many different factors, which will influence health-disease statuses. This partially explains why under similar conditions only some people become sick.
- Trial name
- PETREBED (NCT03146975)
- Testing
- Non-surgical periodontal treatment
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Hyperlipidemia, Periodontitis, Gingivitis
PERIODONTAL DISEASE AND HYPERLIPIDEMIA
The investigators hypothesized that hyperlipidemia as an unfavourable levels of lipoprotein subfractions have deleterious impact on the development of periodontal infection by altering oxidative stres status of periodontal…
- Trial name
- NCT02808130
- Testing
- hyperlipidemia, periodontitis, gingivitis
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Gingiival Hyperpigmentation
Comparison of Gingival Depigmentation Using Microneedling and Microneedling With Glutathione Gel - A Split Mouth Clinical Trial
The colour of gingiva is important determinant of smile esthetics.Owing to increasing awareness and demand for cosmetic procedures over the past decade, gingival depigmentation has gained popularity among periodontal plastic…
- Trial name
- NCT07748507
- Testing
- Microneedling using Dermapen device, Microneedling with 0.5 % Glutathione gel
- Where
- India
- Volunteers
- 15 people
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Sickle Cell Anemia
Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia
The purpose of this study is to determine whether Gum Arabic is effective as fetal hemoglobin inducing agent for sickle cell anemia patients.
- Trial name
- NCT02467257
- Testing
- Gum Arabic
- Where
- Sudan
- Volunteers
- 47 people
- Sponsor
- Al-Neelain University
Periodontal Diseases, Periodontitis
HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy
This observational clinical study aims to investigate the relationship between the HALP score (Hemoglobin × Albumin × Lymphocyte / Platelet), several blood-based inflammatory indices (including NLR, PLR, LMR, and SII), and…
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis; Chronic
- Trial name
- NCT07312045
- Testing
- Non-surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ömer Faruk Okumuş
Gingivitis, Periodontitis
OSE as a Pre-procedural Mouth Rinse: A Clinical and Microbiological Study.
Periodontal disease- Inflammatory, Multifactorial, and Threshold disease. Periodontal disease is a highly prevalent dental disease, an almost 100% prevalence in developing countries.
- Conditions
- Gingivitis, Periodontitis, Aerosol Disease, Gingival Disease
- Trial name
- NCT03839719
- Testing
- Group PI, Group OC, Group CHX
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Post COVID-19 Condition
Periodontal Health in Post COVID-19 Patients
The aim of this study is; To Assess the association between periodontal health and Matrix metalloproteinase-8 (MMP-8) level in Gingival Crevicular Fluid (GCF) in post COVID-19 patients.
- Trial name
- NCT05950230
- Testing
- Assess Periodontal Health Status, Collecte GCF samples by paperstrip
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Periodontal Diseases
Comparison of the Effectiveness of the USG and CBCT Combined With Intraoral Scanning Determing the Gingival Phenotype in the Healthy Periodontium
Compare two diagnostic methods: UGTM and CBCT/CAD/PDIP in determing the gingival phenotype in group of 30 periodontally healthy patients.
- Trial name
- NCT04845581
- Testing
- Diagnostic tests: Determination of the gingival phenotype, measure gingival thickness and width of keratinized tissue
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Gingivitis, Periodontitis
Impact of Periodontal Supportive Therapy in Patients With Gingivitis and Periodontitis
The study evaluated the number of sessions of periodontal supportive treatment in patients with gingivitis in order to evaluate the risk of periodontitis development.
- Trial name
- NCT06382753
- Testing
- Gingival inflammation
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Catania
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