Clinical trials: Gingival Crevicular Fluid
Periodontitis, Healthy
Effect Of Scaling and Root Planning on ALP in Saliva and GCF In Periodontitis Patients Compared With Healthy Individuals
The goal of this [interventional clinical trial] is to test effect of scaling and root plaining on Alkaline phosphatase in Saliva and Gingival crevicular fluid in periodontitis patients compared with healthy subjects The…
- Trial name
- NCT06048016
- Testing
- Scaling and Root Planning
- Where
- Egypt
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases
Periostin and Non-Surgical Periodontal Treatment
A total of 90 subjects, 30 patients with chronic periodontitis, 30 with gingivitis and 30 periodontally healthy subjects were included. Patients with periodontal disease received non-surgical periodontal treatment.
- Trial name
- NCT04332965
- Testing
- Non-Surgical Periodontal Treatment
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Orthodontic Tooth Movement
Impact of Gingival Crevicular Fluid microRNAs on Orthodontic Tooth Movement
A split-mouth study is conducted in order to evaluate the impact of orthodontic movement on the expression of gingival crevicular fluid miRNAs related to inflammation and osteoclastogenesis during canine distalization following…
- Trial name
- NCT06023433
- Testing
- Elastomeric powerchain
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Catania
Growth Indictaor
Gingival Crevicular Fluid Alkaline Phosphatase as Skeletal Growth Indicator
Determination of the pubertal growth spurt in Egyptian female patients using gingival crevicular fluid alkaline phosphatase
- Trial name
- NCT04452071
- Testing
- periapical xray
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Cairo University
Periapical Periodontitis
The Importance of Prostaglandin and Nitric Oxide Synthesis in Apical Periodontitis
A total of 185 subjects were divided into three categories: AP group (n=85), CP group (n=50) and healthy control group (n=50). The AP group was divided into 3 subgroups according to abscess scoring (AS-PAI) based on the…
- Trial name
- NCT06023901
- Testing
- Apical periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Preeclampsia, Periodontal Diseases
Maternal Periodontal Status and Cytokines in Preeclampsia
Background: The purpose of this study is to examine the relationship between maternal preeclampsia and periodontal parameters and the correlation of these two disorders with maternal gingival crevicular fluid levels (GCF) of…
- Trial name
- NCT03088228
- Testing
- gingival crevicular fluid collection
- Volunteers
- 80 people
- Sponsor
- Hacer Sahin Aydinyurt
Chronic Periodontitis
Methodological Evaluation of Gingival Crevicular Fluid Volume and Elastase Level
The mechanisms underlying the formation and composition of gingival crevicular fluid (GCF) and its flow into and from periodontal pockets are not understood very well.
- Trial name
- NCT02676362
- Testing
- Gingival crevicular fluid collection with filter paper
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baskent University
Periodontitis, Prolactin in GCF
The Effect of Non-surgical Periodontal Therapy on the Gingival Crevicular Fluid Levels of Prolactin Hormone in Patients With Periodontitis.
The present study will be conducted on fifty participants. All participants will receive a full-mouth clinical examination, and the following periodontal parameters will be recorded: Plaque Index (PI).
- Trial name
- NCT03726411
- Testing
- non-surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eman Mohamed Amr
Periodontitis, Gingivitis
Fractalkine-CX3CR1 Axis in Periodontal Therapy
This study aimed to evaluate gingival crevicular fluid (GCF) levels of fractalkine/CX3CL1 and CX3CR1 in patients with gingivitis and periodontitis before and after non-surgical periodontal therapy.
- Conditions
- Periodontitis, Gingivitis, Inflammation Biomarkers
- Trial name
- NCT07307144
- Testing
- Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Giresun University
Non-infectious Uveitis, Periodontal Disease
Periodontal Status and Cytokine Levels in Patients With Non-Infectious Uveitis
This cross-sectional observational study aimed to evaluate periodontal clinical parameters and inflammatory cytokine levels in gingival crevicular fluid (GCF), saliva, and serum in patients with non-infectious uveitis (NIU)…
- Trial name
- NIU-PERIO (NCT07480291)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Pregnancy
Matrix Metalloproteinases's in Oral Biofluids During Pregnancy and Postpartum
The aim of this study was to investigate salivary and gingival crevicular fluid (GCF) levels of MMP-8, MMP-9 and TIMP-1 during 2/3 trimester of pregnancy and after delivery
- Trial name
- NCT03516565
- Testing
- Saliva collection, GCF collection
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Periodontal Disease, Adverse Pregnancy Outcome
Correlation Between Inflammatory Markers in Gingival Crevicular Fluid, Serum and Amniotic Fluids in Periodontal Pregnant Women
The main causes of adverse pregnancy outcome(s) are reported to be maternal infection and placental, foetal, or uterine pathosis.
- Trial name
- NCT02022865
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Xerostomia, Sjogren's Syndrome
Gingival Wetness and Gingival Crevicular Fluid Volume in Patients With Dry Mouth
The investigators questioned whether patients with dry mouth complaints display any reduction in residual saliva coating the gingiva and other selected mucosal surfaces.
- Trial name
- NCT00750828
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Hacettepe University
Periodontitis, Periodontitis Stage II
Spirulina Gel in the Treatment of Periodontitis
This randomized clinical trial aims to evaluate the clinical and immunological effects of locally delivered Spirulina gel as an adjunct to scaling and root planing (SRP) in patients with Stage II, Grade B periodontitis.
- Trial name
- non (NCT07893587)
- Testing
- spirulina gel exracted by 1.5% calcium chloride (CaCl2) aqueous solution., conventional scaling and root planing
- Volunteers
- 20 people
- Sponsor
- Misr University for Science and Technology
Inflammation, Periodontal Disease
Advanced Oxidation Protein Product and Monocyte Chemoattractant Protein-1 in Periodontal Disease
This study investigates the levels of advanced oxidation protein product and monocyte chemoattractant protein-1 in gingival crevicular fluid in periodontal disease and health.
- Trial name
- NCT02848378
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Periodontitis, Adult, Periodontal Diseases
Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial
Background: To profile gingival crevicular fluid (GCF) β-Catenin, 8-OHdG, and total antioxidants capacity (TAC) in periodontitis patients during healing of periodontal pockets following non-surgical periodontal therapy…
- Trial name
- NCT07596667
- Testing
- scaling and root planing
- Volunteers
- 21 people
- Sponsor
- Zeyad Nazar
Periodontal Diseases, Periodontal Pocket
Assessment Of Healing After Periodontal Flap Surgery With And Without The Use Of Placental Extracts
All 16 chronic periodontitis (CP) subjects were clinically examined regarding the following clinical periodontal parameters: plaque index (PI), gingival index (GI), bleeding index (BI), Pocket Probing Depth (PPD) and Relative…
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis
- Trial name
- NCT05936450
- Testing
- delivery of placentrex gel after open flap debridement, Open Flap Debridement
- Where
- India
- Volunteers
- 16 people
- Sponsor
- Dr Prabhuji MLV
Healthy Subjects With Fixed Orthodontics
The Effect of Probiotic Lactobacillus Reuteri Prodentis Consumption on Gingival Crevicular Fluid Inflammatory Response and Metagenomic Profiles of Oral Microbiome in Orthodontic Patients.
In this study, researchers will test the effectiveness of probiotic consumption against oral pathogenic bacteria and reduce the occurrence of gingival inflammation in subjects using orthodontic fixed appliances (braces).
- Trial name
- NCT04847960
- Testing
- BioGaia Probiotic Lozenges
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Trisakti University
Periodontal Diseases, Gingivitis
Asprosin, Adropin, Irisin Levels in Periodontitis
The recently discovered association of the hormones 'asprosin, adropin and irisin' with obesity and metabolic status, as well as the fact that periodontal diseases are affected by obesity and nutrition bilaterally, have led us to…
- Conditions
- Periodontal Diseases, Gingivitis, Obesity
- Trial name
- NCT06250764
- Testing
- Clinical periodontal measuremenets, ELISA test from gingival crevicular fluid (GCF)
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- AYSAN LEKTEMUR ALPAN
Pregnancy Gingivitis
The Effect of Periodontal Treatment on Stress and Pregnancy Relationship
There is a relationship between stress and pregnancy gingivitis. This relationship may be double-sided.
- Trial name
- NCT04315532
- Testing
- Non-surgical periodontal treatment, Saliva samples, GCF samples
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University