Clinical trials: Gingival Overgrowth
Gingival Hyperplasia, Dental Plaque
Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients
This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces.
- Conditions
- Gingival Hyperplasia, Dental Plaque, Tooth Demineralization
- Trial name
- NCT07115784
- Testing
- Chlorhexidine Varnish
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Gingival Overgrowth
Folic Acid Supplementation in Phenytoin Induced Gingival Overgrowth
Phenytoin, a common anti-seizure drug, leads to cosmetically unacceptable side effect of gingival overgrowth in a significant number of patients.
- Trial name
- PIGO (NCT00781196)
- Testing
- folic acid
- Where
- India
- Volunteers
- 120 people
- Sponsor
- All India Institute of Medical Sciences
Gingival Overgrowth
Genes Associated With Hereditary and Drug-Induced Gingival Overgrowth
This study will examine common features of gingival overgrowth (excessive growth of the gums around the teeth) that develops in patients with the hereditary form of the condition and in those who develop the condition as a side…
- Trial name
- NCT00104026
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Gingival Overgrowth
The Effect of Platelet-Rich Plasma on Wound Healing After Gingivectomy
The aim of the study is to evaluate the effects of using droplet-form platelet-rich plasma (PRP), known to have positive effects during the intermediate healing process, on wound healing in areas left for secondary healing after…
- Trial name
- PRP (NCT07124143)
- Testing
- PRP
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Duygu Kilic
Immunodeficiency, Skeletal Abnormalities
European Alpha-Mannosidosis Participant
International, multicenter, observational, longitudinal monitoring study to investigate the prevalence of Alpha-Mannosidosis in participants at risk for Alpha-Mannosidosis.
- Conditions
- Immunodeficiency, Skeletal Abnormalities, Deafness, Mental Retardation
- Trial name
- EUMAP (NCT03651245)
- Where
- 19 sites in Germany, Switzerland
- Volunteers
- 667 people
- Sponsor
- CENTOGENE GmbH Rostock
Gingival Overgrowth
Comparison of I-PRF, T-PRF, and 0.8% Hyaluronic Acid Applications in Wound Healing After Gingivectomy.
Objectives: This study aimed to evaluate the effect of injectable platelet-rich fibrin (i-prf), titanium-prepared platelet-rich fibrin (t-prf), and 0.8% hyaluronic acid (HA) gel on clinical periodontal parameters, wound healing…
- Trial name
- NCT06865092
- Testing
- injectable platelet-rich fibrin, titanium-prepared platelet-rich fibrin, Hyaluronic Acid (HA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Gingival Overgrowth
Flapless Esthetic Crown Lengthening for the Treatment of Excessive Gingival Display
The aim of this study is to compare the clinical outcomes of open-flap (OF) and flapless (FL) esthetic crown lengthening (ECL) for the treatment of excessive gingival display (EGD).
- Trial name
- NCT01821157
- Testing
- Open-flap, Flapless
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- University of Guarulhos
Gingival Enlargement
Comparative Evaluation of Hyaluronic Acid Spray and Low-Level Laser Therapy on Wound Healing Following Gingivectomy
Gingival enlargement may impair oral hygiene, esthetics, and periodontal health, and gingivectomy is commonly performed when non-surgical treatment is insufficient.
- Trial name
- NCT07034625
- Testing
- Low Level Laser Therapy, Hyaluronic Acid Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Gingival Enlargement
Evaluation of Healing Process After Laser Asissted Gingivectomy Techniques
Objective: The aim of this study was to evaluate and determine clinical and biochemical comparison of 3 different methods including Er:YAG laser, diod laser, and conventional techniques.
- Trial name
- NCT04304391
- Testing
- Resective Gingival Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Gingival Overgrowth
Assessment of Growth Factors Levels Associated with Wound Healing After Soft Tissue Crown Lengthening
Clinicians often encounter the need for crown lengthening in the practice of dentistry and have to make treatment decisions taking into consideration how to best address the biological, functional, and esthetic requirements of…
- Trial name
- NCT06806319
- Testing
- single intervention by Sirolase ® lower power diode laser 970 ± 15 nm (0.5 watts) continuous emission, power =3 watts, fiber 320 μm, single intervention by electrosurgical unit which was kept 38 watts rms ± 5%. The working frequency was adjusted to 1.5 MHz ± 5%.
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Gingival Overgrowth
Comparison of Dual Digitally Guided vs Conventional Crown Lengthening
This randomized controlled clinical trial aims to evaluate the clinical performance and patient-centered outcomes of dual digitally guided crown lengthening compared to the conventional surgical technique in the management of…
- Trial name
- DIGICROWN (NCT07575087)
- Testing
- Conventional Crown Lengthening, Dual Digitally Guided Crown Lengthening
- Where
- Syria
- Volunteers
- 18 people
- Sponsor
- Arab International University
Peripheral Giant Cell Granuloma, Gingival Lesions
Lymphocyte Subpopulations in Peripheral Giant Cell Granuloma
Peripheral giant cell granuloma (PGCG) is a non-neoplastic inflammatory lesion of gingival tissues. This study aims to evaluate and compare lymphocyte subpopulations in PGCG tissues and adjacent healthy gingival tissues obtained…
- Conditions
- Peripheral Giant Cell Granuloma, Gingival Lesions, Gingival Enlargement
- Trial name
- NCT07551310
- Testing
- Immunohistochemical Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ataturk University
Thickening; Gingival
Assessment of Keratinized Gingiva With and Without PRF Application in Patients With Dental Implant
we used prf with dental implant treatment to find out whether prf has an effect on increasing the soft tissue thickness and keratinized tissue width
- Trial name
- NCT04864197
- Testing
- platelet rich fibrin
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gingival Enlargement
Gingival Hyperplasia Treatment With Surgical Scalpel vs Diode Laser in Orthodontic Patients.
Gingival enlargement is a common complication in orthodontic patients, often resulting from plaque accumulation and chronic inflammatory response during fixed appliance therapy.
- Trial name
- GINGILASCA (NCT07263763)
- Testing
- Scalpel Gingivectomy, Diode laser Gingivectomy
- Where
- Vietnam
- Volunteers
- 13 people
- Sponsor
- Nguyen Thu Thuy
Gingival Overgrowth, Gingival Hyperplasia
Effect of Injectable Platelet-rich Fibrin (i-PRF) on Wound Healing After Gingivectomy
This study evaluates the clinical and biochemical effects of injectable platelet-rich fibrin (i-PRF) on wound healing after gingivectomy, a surgical procedure used to treat gingival overgrowth.
- Trial name
- i-PRF-GIN (NCT07785349)
- Testing
- injectable Platelet-Rich Fibrin (i-PRF), Conventional Gingivectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Şeyma Çardakçı
Gingival Overgrowth
Soft Tissue Wound Healing Following Different Gingivectomy Techniques
The aim of this study was to evaluate the degree of clinical discomfort and the issues experienced by patients and to use a software image program to compare wound healing during the 2-week period following gingivectomy performed…
- Trial name
- NCT03435068
- Testing
- Ceramic rotary bur, Diode laser, Scalpel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- T.C. Dumlupınar Üniversitesi
Chronic Inflammatory Gingival Enlargement
Effect of I-PRF After Gingivectomy
The goal of this clinical trial is to evaluate the effect of injectable platelet-rich fibrin application on wound healing following gingivectomy or gingivoplasty.
- Trial name
- I-PRF (NCT07174934)
- Testing
- application of injectable platelet-rich fibrin on the wound area .
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Gingival Enlargement, Gingival Recession
Development and Validation of the Periodontal Aesthetic Perception Scale in Patients With Periodontal Problems
Aesthetics for individuals become increasingly important, while the aesthetic effects of periodontal disease is an important issue that should be assessed by the patient's perception.
- Trial name
- NCT03436537
- Testing
- Periodontal Aesthetic Perception Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Gingival Enlargement
Efficacy of Hyaluronic Acid Gel and Photobiomodulation on Wound Healing After Surgical Gingivectomy
The aim of this study was to evaluate the effect of hyaluronic acid gel after photobiomodulation on the healing of surgical gingivectomy sites
- Trial name
- NCT05787912
- Testing
- Photobiomodulation, Hyaluronic acid after photobiomodulation
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Gingival Overgrowth
Diode Laser in Gingival Enlargement Related to Orthodontics
Gingival enlargement is one of the most common soft tissue problems associated with fixed orthodontic treatment. The presence of orthodontic appliances impedes oral hygiene measures and alters the oral microbial ecosystem to a…
- Trial name
- NCT01286298
- Testing
- Laser gingivectomy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong