Clinical trials: Gingival Pocket
Diabete Mellitus, Dyslipidaemia
Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years
Overweight and obesity, as well as periodontitis, are common public health problems with increasing prevalence. Both conditions may be linked through shared mechanisms involving chronic low-grade systemic inflammation.
- Conditions
- Diabete Mellitus, Dyslipidaemia, Chronic Kidney Disease, Psychiatric Disorder
- Trial name
- NCT07880717
- Testing
- Periodontal Examination, Questionnaire interview, Anthropometric measurements
- Where
- Thailand
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Infra-bony Periodontal Defect
Effect of Gingival Mesenchymal Stem Cell-Derived Small Extracellular Vesicles in Management of Infra-bony Periodontal Defect
The goal of the study to evaluate whether the adjunctive use of gingival mesenchymal stem cell-derived extracellular vesicles (GMSC-derived EVs) combined with β-tricalcium phosphate (β-TCP) and a collagen membrane results in…
- Trial name
- NCT07867067
- Testing
- Gingival mesenchymal stem cell derived small extracellular vesicles, β-calcium triphosphate (β-TCP) + collagen membrane
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Ain Shams University
Periodontitis, Periodontal Pocket
Amoxicillin Plus Metronidazole in Periodontal Maintenance
Gum disease require a lifetime supportive periodontal care aiming at preventing additional inflammation and bone resorption. During this phase it is also relevant to keep germs under acceptable levels through proper daily hygiene…
- Trial name
- NCT05934227
- Testing
- Amoxicillin 500 milligrams capsules plus metronidazole 400 milligrams
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of Minas Gerais
Chronic Periodontitis, Chronic Periodontitis Wth Diabetes Mellitus
Metabolic Regeneration Registry for Periodontal Health (20-Patient Cohort).
This observational study documents the clinical outcomes of a proprietary, safe-to-swallow metabolic protocol for chronic gum disease.
- Conditions
- Chronic Periodontitis, Chronic Periodontitis Wth Diabetes Mellitus, Non-surgical Periodontal Treatment, Gingival Regeneration
- Trial name
- NCT07538661
- Testing
- Nutraceutical Bio-Active Oral Repair Formula (Food-Grade), Nutraceutical Bio-Active Oral Repair Formula
- Where
- Algeria
- Volunteers
- 20 people
- Sponsor
- Amar h Zireg
Gingival Recession, Localized, Keratinized Tissue
Er,Cr:YSGG Laser for Deepithelialization in Gingival Recession.
Abstract: Introduction: The deepithelialized free gingival graft (DGG) technique provides high-quality connective tissue grafts (CTGs) with predictable outcomes for recession cov-erage.
- Conditions
- Gingival Recession, Localized, Keratinized Tissue, Gingival Thickness, Pocket Depth
- Trial name
- NCT07064304
- Testing
- Laser Deepithelialization of Free Gingival Graft, Scalpel Deepithelialization of Free Gingival Graft
- Where
- Poland
- Volunteers
- 9 people
- Sponsor
- Wroclaw Medical University
Periodontal Pocket, Periodontitis
Treatment Of Shallow Periodontal Pockets 4-6mm Using AIRFLOW Prophylaxis Master Device With Erythritol vs Manual Scalers
Periodontitis is a chronic condition associated with the inflammatory destruction of the periodontal tissues ultimately leading to tooth loss.
- Conditions
- Periodontal Pocket, Periodontitis, Gingival Diseases, Gingival Bleeding
- Trial name
- NCT06351982
- Testing
- Electro Medical Systems AIRFLOW® Prophylaxis Master Device, Hand and ultrasonic scalers and curettes
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis Stage II, Gingival Pocket
Use of Injectable Extended Platelet-Rich Fibrin as a Local Drug Delivery in the Treatment of Stage II Periodontitis Patients
The objective of the present study is to assess the clinical effectiveness of local delivery of injectable extended platelet-rich fibrin in subgingival application when used in conjunction with scaling and root planing (SRP) in…
- Trial name
- NCT07080294
- Testing
- extended platelet rich fibrin injection in pocket, albumin injection in pocket, scaling and root planing
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Chronic Periodontitis, Type 2 Diabetes
The Periodontal Disease and Diabetes Mellitus Interrelationship Among Adult Malaysians
Periodontitis, a chronic inflammatory disease which results in irreversible attachment loss, bone destruction and tooth loss, is a major oral health problem affecting 90.2% of Malaysian population.
- Trial name
- NCT01951547
- Testing
- Nonsurgical periodontal therapy, Oral hygiene instructions
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- University of Malaya
Periodontal Pocket
The Efficacy of Salvia Officinalis Gel in the Treatment of Periodontitis CLINICAL TRIAL
From each participant, two sites of periodontal pockets ( ≥ 5 mm ) were selected and randomly allocated to either the test site (treated with scaling and RSD with S.
- Trial name
- clinical (NCT06900517)
- Testing
- Salvia officinalis Gel
- Volunteers
- 23 people
- Sponsor
- University of Baghdad
Periodontal Diseases, Periodontitis
Interaction Between Immune Cells and Bacteria Associated With Periodontitis
This study evaluates the interaction between host immune cells and bacteria associated with periodontitis. It comprises biological material from donors with and without periodontal disease.
- Conditions
- Periodontal Diseases, Periodontitis, Aggressive Periodontitis, Immunologic Disease
- Trial name
- NCT03225950
- Testing
- In vitro stimulation of blood with periodontitis-associated- and control bacteria, Anti-CCP- and anti-P.g.-antibodies titers, Analysis of selected single nucleotide polymorphisms (SNPs)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periodontitis, Pocket, Periodontal
Adjunctive Effect of Erythritol on Pocket Closure Rates
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis.
- Conditions
- Periodontitis, Pocket, Periodontal, Pocket, Gingival
- Trial name
- NCT06958874
- Testing
- Non-surgical periodontal therapy + sub-gingival air polishing, Non-surgical periodontal therapy alone
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- University of L'Aquila
Periodontitis, Adult, Periodontal Pocket
Effect of Photodynamic Therapy on Gingival Crevicular Cytokines in Periodontitis Patients
Systemically healthy periodontitis patients were recruited in this single-blind, split-mouth, randomized controlled clinical trial. After SRP, PDT was applied at probing depth (PD) ≥ 4 mm at test quadrant.
- Conditions
- Periodontitis, Adult, Periodontal Pocket, Periodontitis, Periodontal Attachment Loss
- Trial name
- NCT03453476
- Testing
- SRP and Fotosan 630
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Periodontitis, Bleeding Gum
Effect of a Hydrogen-Peroxide and Hyaluronic-Acid Mouthwash (BMG0703) in the Treatment of Periodontitis
Assessment of the efficacy of BMG0703 in the treatment of periodontitis and control of supragingival plaque, compared to Chlorhexidine and a placebo product
- Conditions
- Periodontitis, Bleeding Gum, Pocket, Periodontal
- Trial name
- NCT04446533
- Testing
- Hydrogen Peroxide and Hyaluronic acid filming formulation, Chlorhexidine 0.2%
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Periodontal Disease; Gingivitis; Dental Plaque; Malocclusion (Post-orthodontic Treatment)
Digital vs Conventional VFR in Post-Orthodontic Retention
This study is comparing two ways of making a retainer, the clear, removable kind worn after braces to see whether the way it's made affects gum health.
- Trial name
- NCT07760935
- Testing
- Digital Vacuum-Formed Retainer, Conventional Vacuum-Formed Retainer
- Volunteers
- 52 people
- Sponsor
- Ziauddin University
Periodontitis, Periodontitis Chronic Generalized Severe
Effect of Non-surgical Treatment of Periodontitis Patients Focusing on Inflammatory Mediators in Gingival Crevicular Fluid
This study investigates inflammatory biomarkers in gingival crevicular fluid (GCF) from smokers and non-smokers with severe periodontitis, before and during non-surgical periodontal therapy (NSPT).
- Trial name
- NONSURG (NCT07503041)
- Testing
- Collecting fluid for biomarker analyses, Hygiene instruction, tooth cleaning, plaque removal
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Oral Health Centre of Expertise in Western Norway