Clinical trials: Gingival Recession Defects
Gingival Recession
Platelet Rich Fibrin and Autologous Fibrin Glue
Platelet-rich fibrin (PRF) and Autologous Fibrin Glue (AFG) are fibrin preparation derived from human blood samples and are used in regenerative dentistry.
- Trial name
- NCT03734458
- Testing
- Group A - PRF plus AFG with a CAF, Group B - PRF only with a CAF, Group C - CTG with a CAF
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gingival Recession
Efficacy of Methods to Treat Multiple Gingival Recession Defects
Rationale: Treatment of gingival recession defects requires coronal advancement of the gingival margin due to patient esthetic demand, tooth sensitivity and improvement of tooth prognosis, which can be accomplished either through…
- Trial name
- NCT03124329
- Testing
- Coronally Advanced Flap, Intrasulcular Tunneling, Vestibular Incision Subperiosteal Tunnel Access (VISTA)
- Where
- United States
- Sponsor
- University of Southern California
Gingival Recession
A Clinical Trial Testing Root Coverage With Acellular Dermal Matrix in Thin and Thick Gingival Biotypes
Gingival recession is a common defect among the American population. It is also a major cause for root decay, hypersensitivity, contributes to tooth mobility and low self-esteem.
- Trial name
- NCT03057730
- Testing
- Acellular Dermal Matrix
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tufts University
Graft Pain, Gingival Recession
MEBO Ointment and Hyaluronic Acid Gel in the Management of Pain After Free Gingival Graft Harvesting
Postoperative pain as well as bleeding are the most common complications after palatal graft harvesting also postsurgical swelling have been reported , Although different agents were used to protect the denuded areas on the…
- Trial name
- NCT03728244
- Testing
- MEBO ointment, Hyaluronic Acid gel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Inverted T-shape Free Gingival Graft for Treatment of RT2 / RT3 Gingival Recession Defects
The aim of this study is to compare the use of T-inverted shape Free Gingival Graft with Free Gingival Graft for improving the clinical attachment, gain partial root coverage, and improve Keratinized tissue width in recession…
- Trial name
- NCT06615687
- Testing
- Inverted T shape Free Gingival Graft, Free Gingival Graft
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Treatment of Multiple Gingival Recession Defects Using a New Xenogenic Collagen Membrane Compared to Connective Tissue Graft: a Randomized Controlled Split-mouth Clinical Study
Limitation of donor site and significant postoperative morbidity are often described in connective tissue graft. We want to show if mucogain matrix used in tunnel technique to recover RTI Cairo recessions defects could be an…
- Trial name
- Mucogreffe (NCT04800250)
- Testing
- Treatment of gingival recessions
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gingival Recession
Treatment of Multiple Gingival Recessions With a MCAF or a MCAT and a Collagen Matrix
In a recent meta-analysis, Graziani et al. reported that despite the "ideal" treatment for multiple gingival recession defects is not yet identified, there are some indirect suggestions from the analyzed data that, in comparison…
- Trial name
- NCT04225351
- Testing
- MCAF+CM, MCAT+CM
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Gingival Recession
OrACELL™ vs. Connective Tissue in Miller Class 3 Defects
The purpose was to compare root coverage outcomes between autogenous connective tissue graft (CTG) and decellularized human dermis (OrACELL™) in areas of facial gingival recession.
- Trial name
- NCT03226600
- Testing
- OrACELL, Connective Tissue Graft
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Gingival Recession, Localized
Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects
The goal of this randomized clinical study is to assess the root coverage outcomes and patient morbidity following the treatment of single maxillary recession-type defects using a coronally advanced flap (CAF) combined with a…
- Trial name
- NCT06404762
- Testing
- tSCTG+ CAF, pSCTG+ CAF
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession, Gingival Recession, Localized
Coronally Advanced Tunnel Combined With Xenogenic Dermal Matrix and L-PRF
Gingival recession is the exposure of the root surface due to the gum margin moving away from the crown of the tooth. It's common in adults and becomes more prevalent and severe with age.
- Conditions
- Gingival Recession, Gingival Recession, Localized, Mucogingival Defects
- Trial name
- CAF+XADM (NCT06634043)
- Testing
- Coronally Advanced Tunel + ADM (Novomatrix®), Coronally Advanced Tunel + ADM (Novomatrix®) + L-PRF
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Andres Matteo Pascual La Rocca
Gingival Recession
Connective Tissue Grafting for Single Tooth Recession & the Impact of the Thickness of the Palatal Harvest Tissue
The purpose of this study is to test if the thickness of the graft taken from the roof of the mouth, has a significant effect on the amount of attached tissue and the amount of root coverage that are attained when treating a…
- Trial name
- NCT03032094
- Testing
- connective tissue graft
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Columbia University
Gingival Recession
Evaluation of Geistlich Fibro-Gide® + CAF in Comparison to CTG + CAF for the Treatment of Recession Defects at 6 Months
This double blind, randomized, split mouth study evaluates the non-inferiority of Geistlich Fibro-Gide® in comparison to connective tissue graft for the treatment of Miller Class I or II recession defects at 6 months post…
- Trial name
- GFG-US-REC (NCT04260152)
- Testing
- Geistlich Fibro-Gide, Connective Tissue Graft (CTG
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Geistlich Pharma AG
Root Coverage, Tunneling Technique
Root Coverage With Connective Tissue Graft Associated With VISTA Versus Tunnel Technique
Several techniques were proposed in the literature to solve the problems associated with gingival recession. Root coverage was mainly indicated for esthetic concern, however, it might also be indicated for treatment of root…
- Conditions
- Root Coverage, Tunneling Technique, VISTA Technique, Sub Epithelial Connective Tissue Graft
- Trial name
- NCT03690635
- Testing
- VISTA (vestibular incision subperiosteal tunnel acess)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Recombinant Human Fibroblast Growth Factor-2 (rhFGF-2) In Gingival Recession Defects
This study was a single-arm trial to obtain preliminary data on the efficacy of collagen membranes impregnated with recombinant human fibroblast growth factor (rhFGF-2) in the treatment of Miller's class I and class II gingival…
- Trial name
- NCT04361630
- Testing
- FGF 2
- Where
- India
- Volunteers
- 30 people
- Sponsor
- SVS Institute of Dental Sciences
Gingival Recession, Generalized
Cor Adv Flap Plus Ac Derm Matrix in Thin Phenotype Multiple Recessions
Clinical evaluation of conventional and modified coronally advanced flaps combined with acellular dermal matrix graft
- Trial name
- NCT03883438
- Testing
- Modified coronally advanced flap and acellular dermal matrix graft
- Where
- 4 sites in Azerbaijan, Brazil and 2 more
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Aziz Aliyev Azerbaijan State Advanced Training Institute for Doctors
Insufficient Keratinized Tissue, Gingival Recession
Cyanoacrylate Versus Sutures for Free Gingival Graft Stabilization
This randomized controlled clinical trial evaluated the effectiveness of butyl-cyanoacrylate tissue adhesive compared with conventional sutures for stabilization of free gingival grafts.
- Conditions
- Insufficient Keratinized Tissue, Gingival Recession, Mucogingival Defects
- Trial name
- NCT07359300
- Testing
- Free Gingival Graft Stabilization With Butyl-Cyanoacrylate, Free Gingival Graft Stabilization With Sutures
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Gingival Recession, Plastic Surgery
Non-Inferiority of Fibroguide Collagen Membrane Compared to Autologous Connective Tissue Graft for Coverage of Multiple Adjacent Recession. Multicenter Trial.
This study deals with coverage of multiple denuded roots. The current standard treatment requires surgical correction and uses soft tissue taken from the roof of the mouth to enhance results.
- Trial name
- NCT07083050
- Testing
- Volume stable collagen matrix, Autologous Connective Tissue Graft from the Hard Palate
- Where
- 2 sites in Italy, Spain
- Volunteers
- 160 people
- Sponsor
- Maurizio Tonetti
Gingival Recession
Treatment Off Gingival Recession Defects Using a Xenogenic Acellular Dermal Matrix Compared to Connective Tissue Graft.
Limitation of donor site and significant postoperative morbidity are often described in connective tissue graft harvesting. We want to show if mucoderm used in tunnel technique to recover miller class I and II recessions defects…
- Trial name
- MUCODERM (NCT03162016)
- Testing
- transplants
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gingival Recession
Tunnel vs. CAF for the Treatment of Multiple Gingival Recessions
Many studies have compared the tunnel technique and coronally advanced flap in the treatment of single and multiple recessions. However, there is a lack of evidence that compared both techniques in combination with a connective…
- Trial name
- NCT05122468
- Testing
- Connective tissue Harvest and CAF, Connective tissue Harvest and Tunnel
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Periodontitis
RhEGF Incorporated in An Absorbable Collagen Membrane for The Management Of Gingival Recession Defects
A sulcular incision will be made through each recession area and the tissues will be gradually undermined including the base of the interdental papilla.
- Trial name
- NCT04375618
- Testing
- RhEGF, Plain Collagen
- Where
- India
- Volunteers
- 30 people
- Sponsor
- SVS Institute of Dental Sciences