Clinical trials: Gingivitis, completed
Gingivitis and Periodontal Diseases, Tooth Loss
Cement Excess at Single Implant Crowns Malmö/Lund
Abstract Aim: The primary aim of this study is to test whether or not cement residues in the submucosal environment of implants lead to a change in the microbiota and induce inflammation of the periimplant tissues.
- Trial name
- NCT04015427
- Testing
- implant crown
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Gingival Diseases, Gingivitis
Acquired Chronic Erosive Gingivitis: Clinical Relevance of Papillary Gingival Biopsy
Chronic erosive gingivitis is a syndrome (CEGS) that combines severe gingival inflammation and gingival erosion. The term "desquamative gingivitis" is often used in the literature to define chronic erosive gingivitis.
- Conditions
- Gingival Diseases, Gingivitis, Autoimmune Diseases, Oral Lichen Planus
- Trial name
- NCT04293718
- Testing
- papillary gum biopsies
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gingivitis, Plaque
Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided.
- Trial name
- NCT06244303
- Testing
- manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontitis, Gingivitis
PTPIP51-VAPB Complex in the Periodontal Disease
Gum disease, including gingivitis and more advanced periodontitis, is a common condition that damages the tissues supporting the teeth.
- Trial name
- NCT07705048
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingivitis, PCOS
Effect of EE/NETA With Scaling on Periodontium and hsCRP in PCOS Women With Gingivitis
As gingivitis is known to add to the systemic inflammatory burden and may consequently contribute to progression of PCOS and vice-versa, So, controlling local and systemic inflammatory burden by scaling g and medical treatment…
- Trial name
- NCT05129878
- Testing
- scaling and OHI, oral Hygiene instructions, Scaling and oral hygiene instruction
- Where
- 2 sites in India
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Inflammation, Periodontal Diseases
The Role of Diet in Periodontal Inflammation: A Controlled Clinical Study
Diet can influence the body's healing and repair mechanisms. A dietary imbalance obviously cannot trigger periodontal disease in the absence of a primum movens, which is bacterial plaque.
- Trial name
- NCT05864768
- Testing
- Vegan/vegetarian diet, Omnivorous diet
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Periodontal Diseases
Assessment of Salivary Biomarker Levels in Individuals With Various Periodontal Diseases
The aim of this study is to compare the salivary levels of HIF-2 alpha, MMP-9, and TRAP-5b among healthy individuals, patients with gingivitis, and patients with periodontitis; to examine the relationship between these levels and…
- Trial name
- NCT07025291
- Testing
- saliva obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Periodontitis, Periodontal Health
Asprosin Level in Individuals With Periodontal Disease
The aim of this study was to investigate the levels of asprosin hormone and tumour necrosis factor alpha (TNF-α) in gingival crevicular fluids and to compare its level with those in saliva and serum in patients with gingivitis…
- Conditions
- Periodontitis, Periodontal Health, Gingivitis
- Trial name
- ALIGCF (NCT06627972)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Gingivitis, Periodontal Disease
Touch-to-Teach Interdental Brush Instruction Versus Conventional Guidance on Gingival Health in Patients With Fixed Dental Prostheses
Why is this study being done? People with dental crowns often develop inflamed gums because bacteria accumulate in the tight spaces between teeth that a regular toothbrush cannot reach.
- Conditions
- Gingivitis, Periodontal Disease, Fixed Dental Prosthesis, Dental Plaque
- Trial name
- NCT07636954
- Testing
- Touch-to-Teach interdental brush instruction, Conventional oral hygiene instruction
- Where
- United Arab Emirates
- Volunteers
- 32 people
- Sponsor
- Gulf Medical University
Periodontal Diseases
Clinical and Microbiological Evaluation Of The Efficacy Of Herbal Mouthwashes in Gingivitis
Plaque-induced gingivitis is a clinical condition that appears to cause persistent inflammation in gingiva. It is a preliminary cause to periodontitis but it can be inverted to address the risk of periodontitis development.
- Trial name
- NCT06904742
- Testing
- Tea tree oil, Thyme oil hydrosol, LISTERINE ZERO Alcohol Mouthwash COOL MINT
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Chronic Gingivitis, Plaque Induced
Comparative Evaluation of Guava Leaf Extract and Chlorhexidine Mouthwash in Patients With Chronic Gingivitis
The goal of this clinical trial is to compare the effectiveness of 0.15% guava (Psidium guajava) leaf extract mouth rinse with 0.2% Chlorhexidine (CHX) mouth rinse in reducing plaque accumulation, gingival inflammation, and oral…
- Trial name
- NCT07059572
- Testing
- Group A- 0.15% Guava leaf extract mouthwash group, Group B- 0.2% Chlorhexidine mouthwash
- Where
- Bangladesh
- Volunteers
- 160 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Dental Caries, Gingivitis
Oral Hygiene Intervention Pilot Study
The main goals of this pilot study are to develop a nursing home-customized oral hygiene protocol, intended to be delivered primarily by dental hygienists and primary care providers, and to identify potential obstacles and…
- Trial name
- NCT02668809
- Testing
- oral health assessment, Questionnaires, Clinical Exam
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Leonardo Marchini
Gingival Inflammation, Plaque
The Effectiveness of Brushing and Flossing Sequence on Control of Plaque and Gingival Inflammation
This study evaluates the effectiveness of brushing and flossing sequence in the control of dental plaque and gingival inflammation.
- Conditions
- Gingival Inflammation, Plaque, Gingival Bleeding, Plaque Control
- Trial name
- RCT (NCT03989427)
- Testing
- Brushing first and Flossing later (BF), Flossing first and Brushing later (FB)
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Gingival Hemorrhage, Gingivitis
Intra-oral Camera in Gingival Health
Evaluate the effects of using an intra-oral camera (IOC) during supportive periodontal therapy (SPT), on the psychological, behavioral and clinical parameters of patients with gingivitis, outlined by evidence and a theory-based…
- Conditions
- Gingival Hemorrhage, Gingivitis, Health Behavior, Communication
- Trial name
- NCT02725983
- Testing
- SPT consultation, SOPROCARE®
- Volunteers
- 78 people
- Sponsor
- University of Lisbon
Gingivitis, Periodontitis
Efficacy of ClōSYS® Sensitive Fluoride Toothpaste and ClōSYS® Sensitive Rinse Regimen on MGI, PI and BOP
90-day, self-controlled, longitudinal, non-blinded clinical trial which will measure changes in clinical parameters in participants with gingivitis and Stage I or II periodontitis who apply ClōSYS® Sensitive Fluoride Toothpaste…
- Trial name
- NCT05258721
- Testing
- ClōSYS® Sensitive Fluoride Toothpaste, ClōSYS® Sensitive Rinse
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rowpar Pharmaceuticals, Inc.
Periodontitis, Gingivitis
Activin-A and Interleukin-1β Levels in Periodontitis
Activin-A belongs to the transforming growth factor-beta superfamily and is a multifunctional cytokine that plays a role in inflammation, immune response, tissue repair and regeneration.
- Conditions
- Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT06110221
- Testing
- Periodontal clinical measurements, GCF and saliva sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gingivitis
To Compare the Effectiveness of Three Self-care Oral Hygiene Regimens
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04804670
- Testing
- Power device A, Power device B, Routine Oral Hygiene
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Chronic Gingivitis
Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis.
Present work was to investigate the possible efficacy of 0.2% cuminum cyminum herbal preparation as an antiplaque and antigingivitis agent when compared with chlorhexidine.
- Trial name
- NCT04767269
- Testing
- Cuminum Cyminum, herbal Mouthwash
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Periodontitis, Dental Implants
Marginal Bone Level Around Dental Implants in Periodontitis Patients
This study evaluates and compares marginal bone level changes around dental implants with two different surface characteristics in patients with a history of periodontitis.
- Conditions
- Periodontitis, Dental Implants, Marginal Bone Loss, Periodontal Probing Depth
- Trial name
- (MBL) (NCT07608523)
- Testing
- SLA Dental Implant, Plasma Spraying Dental Implant
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Periodontitis, Periodontal Diseases
Vitamin D Supplementation Prior to Non-surgical Periodontal Therapy
The purpose of this study is to test the feasibility i. e. to examine all aspects necessary for the implementation of a future randomized clinical trial (RCT) that aims to determine whether non-surgical periodontal treatment can…
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Inflammation, Inflammation
- Trial name
- NCT05398770
- Testing
- Vitamin D supplementation (30 µg/d)
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- University of Tromso