Clinical trials: Gingivitis, completed
Periodontal Diseases
"Effect of CPA/EE Drug on Periodontal Tissue and hsCRP Levels in PCOS Patients With Gingivitis
PCOS is a widely reported condition among young female population and anti-androgen agents are increasingly being used as part of the medical management of such cases.
- Trial name
- NCT05657171
- Testing
- cyproterone Acetate/Ethinyl Estradiol Combination
- Where
- India
- Volunteers
- 47 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Tooth Discoloration, Tooth Sensitivity
At-home Bleaching Using Clear Retainers
The aim of this project is to clinically evaluate patient satisfaction, whitening efficacy, tooth sensitivity, and gingival irritation during at-home whitening with 10% carbamide peroxide using an Essix-type retainer or a Vivera…
- Conditions
- Tooth Discoloration, Tooth Sensitivity, Gingivitis, Satisfaction, Patient
- Trial name
- NCT05835453
- Testing
- Whitening
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Mouth Diseases, Periodontal Inflammation
Evaluation of Biomarkers Levels in Gingival Crevicular Fluid, Saliva and Serum for Different Periodontal Diseases
The aim of this study is; detection of interleukin(IL)-38, IL-36 gamma(γ) , IL-17 and matrix metalloproteinase(MMP)-9 levels in gingival crevicular fluid (GCF), saliva and serum samples of periodontally healthy, gingivitis and…
- Conditions
- Mouth Diseases, Periodontal Inflammation, Periodontal Diseases
- Trial name
- NCT05435131
- Testing
- GCF obtaining, Saliva Obtaining, Serum obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Gingivitis
Effects on Tablets Containing Probiotic Candidate Strains
The aim of the study is to investigate the effect of tablets containing probiotic candidate strains, on gingival inflammation and the levels of selected pro- and anti-inflammatory cytokines in gingival crevicular fluid (GCF).
- Trial name
- NCT02633345
- Testing
- Probiotic tablets
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Copenhagen
Mild Cognitive Impairment, Gingivitis
eDENT Oral Health- the Gateway to Quality of Care and Everyday Life at Old Age
The investigators will present a new strategy for working with oral health for the group of elderly people with various degrees of mild cognitive impairments.
- Conditions
- Mild Cognitive Impairment, Gingivitis, Periodontal Diseases
- Trial name
- NCT06011564
- Testing
- Reminder function on Android computer tablet
- Where
- Sweden
- Volunteers
- 213 people
- Sponsor
- Blekinge Institute of Technology
Behavior and Behavior Mechanisms, Gingivitis
A 8-month Study on the Use of Intra-oral Camera and Text Messages on Gingivitis Control
To investigate the effects of using an intra-oral camera (IOC) during supportive periodontal therapy, and oral hygiene mobile text messages (SMS) between appointments on clinical, behavioral and psychological parameters of…
- Trial name
- NCT03439969
- Testing
- Mobile Text Messages, Intra Oral Camera
- Volunteers
- 233 people
- Sponsor
- University of Lisbon
Gingivitis, Plaque
ToothWave Plaque and Gingivitis Study
The objective of the study is to evaluate the safety and efficacy of the home-use device Silk'n toothbrush (ToothWave) for the improvement in dental health through the reduction of plaque, gingivitis, and calculus.
- Conditions
- Gingivitis, Plaque, Calculus, Dental
- Trial name
- NCT03885323
- Testing
- RF utilizing powered toothbrush
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Dental Plaque
Comparison of the Clinical and Microbiological Effects of CHX and HOCl Containing Mouthwashes
The primary objective of the study is to compare the antiplaque and anti-inflammatory effects of HOCl mouth rinse with those of CHX mouth rinse.
- Trial name
- NCT06589193
- Testing
- HOCl, CHX
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Baskent University
Gingivitis
The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms
Dental plaque is a well known etiologic factor for gingivitis. Recently, herbal extracts are a matter of scientific interest to inhibit plaque accumulation on teeth.
- Trial name
- NCT00972803
- Testing
- pistacia Mutica extract, Chlorhexidine
- Where
- Iran
- Volunteers
- 25 people
- Sponsor
- Tabriz University
Periodontal Diseases, Gingivitis
Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract
Chlorhexidine is considered as gold standard for its antiplaque and antigingivitis efficacy till date but it has got many side effects.
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis
- Trial name
- NCT03474146
- Testing
- Ocimum sanctum, Chlorhexidine Gluconate, Propylene Glycol
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Periodontal Diseases
Periodontal Status and Endothelial Dysfunction in Patients With Polycystic Ovary Syndrome
Emerging research indicates a link between polycystic ovary syndrome (PCOS) and periodontal diseases, revealing the intricate relationship between oral health and systemic conditions.
- Trial name
- NCT06184412
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Tooth Abrasion, Gingival Recessions
The Effect of Retraction Cord on the Surrounding Periodontal Tissues in Restorative Treatment
The goal of this clinical trial is to learn whether a retraction cord affects gum health when used during tooth restoration procedures.
- Conditions
- Tooth Abrasion, Gingival Recessions, Non-Carious Cervical Lesions (NCCLs), Periodontal Health
- Trial name
- NCT07734935
- Testing
- Gingival Retraction Cord, Composite Resin Restorative, Universal Adhesive - G-Premio Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Istanbul University
Periodontal Diseases, Gingivitis
ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE
This cross-sectional study aims to evaluate the relationship between oral hygiene habits, periodontal status, and oral health-related quality of life in adult individuals.
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis
- Trial name
- NCT07530978
- Testing
- Oral Health Assessment and OSHIP-Perio Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingivitis, Ultra-processed Food
Impact of Ultra-Processed Food Intake on Gingival Tissue Health
The shift towards consuming more industrialized food products, particularly ultra-processed foods, has been linked to a rise in non-communicable diseases globally.
- Conditions
- Gingivitis, Ultra-processed Food, Prevention
- Trial name
- NCT06411535
- Testing
- Full-mouth ultrasonic debridement plus Nutritional counseling, Full-mouth ultrasonic debridement
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- University of Siena
Polycystic Ovary Syndrome, Gingival Inflammation
Impact of PCOS on Periodontal Status of Adolescent and Adult Age Group Women
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women, primarily affecting the reproductive system, with substantial collateral negative health effects on metabolic, psychological, and cardiovascular…
- Trial name
- NCT05113030
- Testing
- PERIODONTAL STATUS OF FEMALE PATIENTS WITH PCOS (NEWLY DIAGNOSED) OF ADOLESCENT AGE GROUP WILL BE ASSESSED, PERIODONTAL STATUS OF FEMALE PATIENTS WITH PCOS (NEWLY DIAGNOSED) OF ADULT AGE GROUP WILL BE ASSESSED
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingivitis, Maxillary Transversal Deficiency
St. John's Wort Oil Versus Chlorhexidine Mouthwash for Gingival Problems After Rapid Maxillary Expansion
The goal of this clinical trial was to learn whether St. John's wort (Hypericum perforatum) oil helps gum healing in children and adolescents aged 11 to 16 years after treatment with a rapid maxillary expansion appliance.
- Trial name
- SJW-CHX-RME (NCT07882771)
- Testing
- St. John's Wort Oil, Chlorhexidine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Inhibition of Plaque Formation (by Gingivitis-Index ≤1.5)
Study to Assess the Inhibition of Plaque Formation in Subjects With a Gingival Index ≤1.5
The objective of the study is to demonstrate the superiority of 0.1% octenidine mouthwash (Octenidin Mundspüllösung, OML) to placebo (PLAC) in the inhibition of plaque formation.
- Trial name
- NCT03378401
- Testing
- Octenidinedihydrochlorid
- Where
- 3 sites in Austria, Germany
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Schülke & Mayr GmbH
Gingivitis
A Clinical Trial to Evaluate Long-term Efficacy and Safety of Lozenges Containing Lactobacilli Reuteri (Prodentis™) on Gingivitis
The purpose of this study is to evaluate the long-term efficacy and safety of lozenges containing probiotics in reducing gingivitis. The primary purpose of this study is to support claims from U.S.
- Trial name
- NCT01811316
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Sunstar Americas
Gingivitis
A Study to Determine the Effects of Adding an Experimental Device With Mouthrinse to Oral Care Regimen
The study will determine the effects of adding mechanical plaque control to a person's oral care regimen. Participants who qualify to participate in the study will will have an equal chance of being assigned to one of three…
- Trial name
- NCT01419626
- Testing
- Interdental cleaning device with water, Interdental cleaning device with essential-oil mouthrinse
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Gingivitis
The Efficacy of Full Mouth Erythritol Powder Air-Polishing Therapy (FM-EPAPT) Versus Traditional Ultrasonic Debridment (UD): a Randomized Controlled Study.
Traditional methods for plaque and calculus removal involve the use of mechanical and/or manual instruments, followed by surface polishing with rubber cups and low abrasive pastes.
- Trial name
- ERICO (NCT04455269)
- Testing
- AIRFLOW® with PLUS® powder and PIEZON® scaler, PIEZON® scaler and rubber cup with abrasive paste
- Where
- Italy
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia