Clinical trials: Gingivitis, open to volunteers
Gingivitis, Periodontitis
EFFECTIVENESS OF ORAL HYGIENE INSTRUCTIONS GIVEN BY AI-GENERATED VIDEOS VS. TRADITIONAL APPROACH IN PERIODONTAL PATIENTS
Patients attending Dubai Dental Hospital and requiring nonsurgical periodontal therapy will be invited to take part in the study.
- Trial name
- OHI (NCT06622863)
- Testing
- Standard oral hygiene instructions will be given verbally by the periodontics resident, Avatar-based group will receive oral hygiene instructions from a digital avatar of their choice
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Periodontal Diseases, Periodontitis
Evaluation of the Effects of Probiotic Toothpastes on Periodontal Health
This controlled, randomized clinical study aims to evaluate the possible effects of probiotic toothpaste on the success of periodontal treatment in smokers and non-smokers with clinical data.
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis
- Trial name
- NCT06514664
- Testing
- Using Probiotic Toothpaste
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Plaque, Dental Plaque
Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems
Qualified subjects will be enrolled and randomized to either one of the three study groups described above based on their initial modified gingivitis and plaque scores.
- Conditions
- Plaque, Dental Plaque, Gingivitis
- Trial name
- NCT07842991
- Testing
- 0.45% SnF HW with NaF (1450 F), 67% Bicarbonate with NaF (1400 F), Colgate Cavity Protection Toothpaste
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Inflammation, Dental Plaque
Bacteria in Dental Plaque and Atheroma Plaque
Periodontitis is considered a focus of infection where oral bacteria, bacterial by-products or inflammatory mediators can interact with other parts of the organism via the blood.
- Conditions
- Gingival Inflammation, Dental Plaque, Atheroma Plaque, Oral Bacteria
- Trial name
- NCT07100574
- Testing
- atheroma plaque, dental plaque
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Saglik Bilimleri University
Elderly, Periodontal Disease
Oral Hygiene Assistance Training Program
This is an oral health study with a nursing home staff training program and product intervention.
- Conditions
- Elderly, Periodontal Disease, Gingivitis, Caries,Dental
- Trial name
- NCT07807397
- Testing
- Stannous Fluoride Toothpaste (SnF), sodium fluoride 5000 ppm, cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontitis, Pocket, Periodontal
Adjunctive Effect of Erythritol on Pocket Closure Rates
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis.
- Conditions
- Periodontitis, Pocket, Periodontal, Pocket, Gingival
- Trial name
- NCT06958874
- Testing
- Non-surgical periodontal therapy + sub-gingival air polishing, Non-surgical periodontal therapy alone
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- University of L'Aquila
Gingivitis
Effectiveness of Oil Pulling Using Oils in Comparison With Mouthwash for Gingivitis
The goal of this clinical trial is to learn if daily oil pulling with coconut oil or sesame oil works as effectively as a standard mouthwash to treat gum swelling and redness (gingivitis) in adults aged 18 to 55 years.
- Trial name
- NCT07892235
- Testing
- coconut oil, Sesame Oil, 0.2% Chlorhexidine Mouthwash
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Bahria University
Plaque-Induced Gingivitis
Efficacy of Thymus Vulgaris Mouthwash in the Management of Biofilm-Induced Gingivitis
The goal of this clinical trial is to determine whether a mouthwash made from thyme (Thymus vulgaris) helps improve gum health in people with plaque-induced gingivitis.
- Trial name
- NCT07905456
- Testing
- 0.2% Thymus vulgaris mouthwash, Chlorhexidine 0,12%
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Sulaimani
Gingivitis, Gingivitis; Chronic
A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental Students
This multicentre randomised controlled trial aims to evaluate the efficacy and safety of the SMILETM (Siwak Method for Integrated Lifestyle Enhancement) module in improving short-term periodontal outcomes, oral hygiene behaviour…
- Trial name
- SMILE (NCT07702383)
- Testing
- SMILE Module, Conventional Toothbrushing Module
- Where
- 4 sites in Malaysia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Gingivitis
Comparison of the Efficacy of Oral Irrigator Versus Interdental Brushes in the Oral Hygiene of Patients With Gingivitis: a Randomised Study
Periodontal health is a public health issue because of the frequency of periodontal disease (more than 50% of the French population suffers from severe periodontitis (Bourgeois, Bouchard and Mattout 2007)), its negative impact on…
- Trial name
- Hydro-Paro (NCT07005011)
- Testing
- oral irrigator
- Volunteers
- 340 people
- Sponsor
- Université de Reims Champagne-Ardenne
Bacteremia, Infective Endocarditis
Reducing Risk for Infective Endocarditis
This clinical trial is studying if bacteria found in a participant's bloodstream after brushing their teeth can be prevented with a dental cleaning and more education on how to best brush and care for their teeth.
- Trial name
- PIE-B (NCT05721781)
- Testing
- Oral Hygiene instruction, Dental Cleaning
- Where
- 6 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Gingivitis
Clinical Study Examining the Control of Plaque and Gingivitis
The objective of this six-month clinical investigation is to evaluate the efficacy of a silica-free meridol toothpaste versus Colgate Cavity Protection Toothpaste in the control of established dental plaque and gingivitis.
- Trial name
- NCT07842978
- Testing
- Silica Free Meridol, Meridol, Colgate Dental Product
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Pregnant Woman
Pregnancy Women and Individual Oral Prophylaxis in the Control of Gingival Inflammation (PRE-IOP)
Gingivitis in pregnant women is a common inflammatory periodontal disease that appears from the third month of pregnancy with an overall prevalence of 35 to 100%.
- Trial name
- PRE-IOP (NCT05945225)
- Testing
- Sonicare DiamondClean 9000 Philips®, HydroSonic Easy Curaden®, Manual toothbrush Oral-B 123
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Claude Bernard University
Dental Calculus, Gingivitis and Periodontal Diseases
Bio-Descaling Toothpaste for Dental Calculus Reduction
Dental calculus is a calcified mineralized plaque composed primarily of calcium phosphate salts covered by an unmineralized bacterial biofilm layer.
- Conditions
- Dental Calculus, Gingivitis and Periodontal Diseases, Periodontal Diseases
- Trial name
- AntiCal (NCT07689071)
- Testing
- Bio-Descaling Powder (BDP) Toothpaste
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Oral Health Related Quality of Life (OHRQoL)
New Functional Ingredient for Oral Care
The goal of this clinical trial is to find new ingredients for oral care products that can improve gum health. We want to learn if new botanical blends can help reduce gum inflammation, strengthen the gum's natural barrier, and…
- Trial name
- NCT07771907
- Testing
- Botanical A, Botanical B
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Periodontal Health, Gingivitis
Salivary and GCF Biomarkers in Periodontal Health, Gingivitis and Periodontitis
This observational cross-sectional study aims to compare the levels of irisin, interleukin-6 (IL-6), interleukin-10 (IL-10), and tumor necrosis factor-alpha (TNF-α) in saliva and gingival crevicular fluid (GCF) among individuals…
- Conditions
- Periodontal Health, Gingivitis, Periodontitis
- Trial name
- NCT07881406
- Testing
- Clinical periodontal examination, ELISA-based biomarker analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Dental Plaque, Gingivitis
The Study to Evaluate the Plaque Control and Anti-Gingivitis Efficacy of a Toothpaste in Chinese Population
The aim of this study is to evaluate the efficacy of the test toothpaste compared to a regular fluoride toothpaste in the reducing gingivitis and plaque accumulation in Chinese participants with plaque-induced gingivitis.
- Trial name
- NCT07816406
- Testing
- Test Toothpaste, Regular Fluoride Toothpaste
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- HALEON
Autism Disorder, Autism Spectrum Disorder (ASD
Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian Children
The present study will be performed to evaluate the effectiveness of peer modeling and audiovisual peer modeling video on toothbrushing skills in comparison to the visual pedagogical method at home.
- Conditions
- Autism Disorder, Autism Spectrum Disorder (ASD, Autism, Plaque Reduction
- Trial name
- Autism ASD (NCT07859696)
- Testing
- Peer model, Pre-recorded video of peer modeling, Pedagogical method
- Volunteers
- 90 people
- Sponsor
- Faculty of Dental Medicine for Girls
Diabete Mellitus, Dyslipidaemia
Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years
Overweight and obesity, as well as periodontitis, are common public health problems with increasing prevalence. Both conditions may be linked through shared mechanisms involving chronic low-grade systemic inflammation.
- Conditions
- Diabete Mellitus, Dyslipidaemia, Chronic Kidney Disease, Psychiatric Disorder
- Trial name
- NCT07880717
- Testing
- Periodontal Examination, Questionnaire interview, Anthropometric measurements
- Where
- Thailand
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Mahidol University