Clinical trials: Girls
Bladder Cancer
Celecoxib With Chemotherapy in Localized, Muscle-Invasive Bladder Cancer
The purpose of this study is to compare patient tumor tissue before and after treatment with chemotherapy plus celecoxib. Investigators will look at gene expression, to see what effect celecoxib may have on tumor cells.
- Trial name
- BLAST (NCT02885974)
- Testing
- Celecoxib, Gemcitabine, Cisplatin
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Baylor College of Medicine
Bladder Cancer, Bladder Carcinoma
Chemoradiation for Bladder Preservation After Complete Response to Neoadjuvant Chemotherapy
Bladder preservation in patients with complete response after neoadjuvant chemotherapy will lead to equivalent or superior relapse free rates compared to cystectomy rates from historical controls.
- Conditions
- Bladder Cancer, Bladder Carcinoma, Transition Cell Cancer, Muscle Invasive Bladder Carcinoma
- Trial name
- NCT02145390
- Testing
- Transurethral Resection of the Bladder Tumor & Cystoscopy, Intensity Modulated Radiation Therapy, Expanded Prostate Cancer Index Composite Short Form 12
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Miami
Prospective Studies, Heart Failure
Correlation Between Peripheral Venous Pressure and Central Venous Pressure in the Cardiac Intensive Care Unit
In patients admitted to a coronary care unit, what is the correlation coefficient and limits of agreement for paired measurements of peripheral venous pressure and central venous pressure at multiple time points during the…
- Trial name
- NCT03526497
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The Cleveland Clinic
Epilepsy, Diabetic Nephropathy
Study on the Population Pharmacokinetics of Levetiracetam in Epileptic Patients With Diabetic Kidney Disease
The individualized drug delivery system of levetiracetam based on population pharmacokinetics and quantitative pharmacology model in patients with epilepsy complicated by diabetic kidney disease was established.
- Trial name
- NCT05330390
- Testing
- Levetiracetam
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Second Hospital of Shandong University
Atherosclerosis, Chlamydia Infections
Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections
Hardening of the arteries (atherosclerosis) and heart disease are much more common in men than in women. However, as women grow older, especially after menopause the incidence of atherosclerosis and heart disease increases.
- Conditions
- Atherosclerosis, Chlamydia Infections, Cytomegalovirus Infections, Pneumonia, Bacterial
- Trial name
- NCT00001890
- Testing
- Estrogen therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Kidney Diseases, Haemodialysis
Live Classical Music and the Response to the Disease and Its Evolution in Patients With Chronic Renal Failure
People are most vulnerable to anxiety when faced with life-threatening situations such as illness, medical treatments and surgeries.
- Trial name
- NCT05729997
- Testing
- Listening to live classical music
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitario La Fe
Postpartum Hemorrhage
Introduction of UBT for PPH Management in Three Countries
This study is a prospective, systematic evaluation to assess the effectiveness and safety of introduction of UBT into PPH care at secondary level and district hospitals in 3 low-resource countries.
- Trial name
- UBT (NCT02910310)
- Testing
- Uterine balloon tamponade
- Where
- 18 sites in Egypt, Senegal and 1 more
- Volunteers
- 60,105 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Diet Habit, Endometrial Polyp
Observational Study of the Association Between Food Intake and Endometrial Polyps
There are currently no studies evaluating the association between diet and the incidence of endometrial polyps. We aim to evaluate the association to provide more recommendations for the early prevention of endometrial polyps.
- Conditions
- Diet Habit, Endometrial Polyp, Women
- Trial name
- NCT06295510
- Testing
- No interventions.
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- qinxiu zhang
Cervical Intraepithelial Neoplasia
Efficacy Study of Diathermy Cone Biopsy for the Treatment of Cervical Intraepithelial Lesion
The purpose of this trial is to determine whether SWETZ (Straight Wire Excision of Transformation Zone) is a superior alternative to LLETZ cone (Large Loop Excision of Transformation Zone cone biopsy) in the management of…
- Trial name
- NCT00995020
- Testing
- Straight Wire Excision of Transformation Zone, Large Loop Excision of Transformation Zone (cone biopsy)
- Where
- 2 sites in Brazil
- Volunteers
- 103 people
- Sponsor
- Oswaldo Cruz Foundation
Polycystic Ovary Syndrome
Polycystic Ovary Syndrome Genetics and Treatment Response
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women. Women with PCOS have a high risk of prediabetes, type 2 diabetes and heart disease.
- Trial name
- NCT01389778
- Testing
- Metformin ER, Metformin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Ovariectomy, Hysterectomy
Surveillance Study of Women Taking Intrinsa®
The primary objective of the study is to assess the risks of testosterone transdermal patch use in a representative study population. The primary clinical outcome of interest is breast cancer.
- Conditions
- Ovariectomy, Hysterectomy, Hypoactive Sexual Desire Disorder
- Trial name
- EMPOWER (NCT00551785)
- Where
- Germany
- Volunteers
- 328 people
- Sponsor
- Center for Epidemiology and Health Research, Germany
HIV Antiretroviral Therapy (ART) Adherence, Perinatal Mental Health
Prevention of Mother-to-child Transmission (PMTCT) Among Women Experiencing Depression in Malawi
Prevention of mother-to-child transmission (PMTCT) of HIV virtually eliminates transmission of HIV from mothers to their infants.
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, Perinatal Mental Health, Depression During Pregnancy, PMTCT
- Trial name
- NCT06659315
- Testing
- Couples Problem Solving Therapy
- Where
- Malawi
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Chronic Kidney Disease, Proteinuria
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine.
- Trial name
- FIONA (NCT05196035)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 132 sites in United States, Argentina and 30 more
- Volunteers
- 219 people
- Sponsor
- Bayer
Multiple Myeloma, Renal Failure
High Dose Therapy Followed by Autologous Transplantation for Myeloma Patients With Severe Renal Impairment
Multiple myeloma (MM) is a malignant plasma cell disorder, characterized by the presence of more than 10 % of clonal plasma cells in the bone marrow.
- Trial name
- IRMYG (NCT03234335)
- Testing
- Data collection
- Where
- 33 sites in Algeria, Belgium and 2 more
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Chronic Kidney Diseases
the Effect of Virtual Reality Exercise on Selected Electrolytes Levels in Intradialytic Patients
this study will be conducted to investigate the effect of Intra-Dialysis virtual reality exercise on selected electrolytes balance in patients with end stage renal disease.
- Trial name
- VRE (NCT07316725)
- Testing
- Virtual Reality Exercise, standard care
- Volunteers
- 40 people
- Sponsor
- Cairo University
Lupus Nephritis
Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis
The purpose of this study is to evaluate (Abatacept) for treatment of lupus nephritis when used on a background of Cellcept (mycophenolate) and prednisone (corticosteroids)
- Trial name
- NCT01714817
- Testing
- BMS-188667, Mycophenolate mofetil, Prednisone
- Where
- 149 sites in United States, Argentina and 21 more
- Volunteers
- 695 people
- Sponsor
- Bristol-Myers Squibb
Carcinoma, Renal Cell
A Phase II Trial of Gemcitabine, Capecitabine, and Bevacizumab in Metastatic Renal Cell Carcinoma
The purpose of this study is to find out what effects (good and bad) the combination of the chemotherapy drugs gemcitabine, capecitabine, and bevacizumab has on a patient and kidney cancer.
- Trial name
- NCT00523640
- Testing
- combination of gemcitabine, capecitabine, and bevacizumab
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Reproductive Health, Herpesvirus Infection
Cups or Cash for Girls Trial to Reduce Sexual and Reproductive Harm and School Dropout
A 4-armed cluster randomised controlled trial conducted among secondary schoolgirls in Siaya, western Kenya, where clusters are the unit of allocation and schoolgirls the unit of measurement.
- Conditions
- Reproductive Health, Herpesvirus Infection, HIV Infections, Woman Abuse
- Trial name
- CCg (NCT03051789)
- Testing
- Menstrual Cup, Cash transfer, Cups and Cash
- Where
- Kenya
- Volunteers
- 4,138 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Endometriosis
Comparison Between the Effects of Implantable Gestrinone and Oral Dienogest in the Treatment of Endometriosis
This study aims to evaluate the effects of therapy with implantable Gestrinone compared to oral Dienogest in relieving complaints related to endometriosis.
- Trial name
- NCT06543550
- Testing
- Implantable gestrinone, Oral Dienogest
- Where
- 4 sites in Brazil
- Volunteers
- 70 people
- Sponsor
- Bio Meds Pharmaceutica Ltda
Pelvic Floor Disorders
Pelvic Floor Muscle Contraction During Hypopressive Exercise in Women With Pelvic Floor Dysfunction
The purpose of this randomized controlled trial is to compare the effectiveness of different modalities of hypopressive exercise in women with pelvic floor dysfunction.
- Trial name
- HIPOSPFD (NCT04336150)
- Testing
- Hypopressive exercises, Hypopressive maneuver, Hypopressive exercises plus pelvic floor muscle contraction
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Alcala
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