Clinical trials: Glaucoma, Suspect
Glaucoma, Congenital Cataract
Glaucoma After Congenital And Infantile Cataract Surgery
Pediatric patients who have undergone surgery for congenital or infantile cataracts have a risk of developing suspected glaucoma and glaucoma, but the current evidence does not address our understanding of the incidence and…
- Trial name
- NCT04131114
- Where
- China
- Volunteers
- 241 people
- Sponsor
- Sun Yat-sen University
Glaucoma, Suspect, Aberration, Corneal Wavefront
Ocular Changes With Alpha-2 Receptor Agonist.
selective alpha-2 receptor agonists cause changes in intraocular pressure and pupillary size thus may affect patient quality of life.
- Trial name
- NCT05670015
- Testing
- Low dosage selective alpha-2 receptor agonists topical eyedrop, High dosage selective alpha-2 receptor agonists topical eyedrop
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Benha University
Glaucoma, Suspect, Glaucoma
Diagnostic Performance of Smart Supra Perimetry (The DPSSP Study)
Early glaucomatous visual field changes can be missed with the routinely used Standard Automated Perimetry (SAP) and the 24-2 test pattern due to limited sampling of the central 10 degrees.
- Trial name
- DPSSP (NCT03978546)
- Testing
- Humphrey Visual Field Test, Optical Coherence Tomography (OCT) Scan, Smart Perimetry - Henson 9000
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Glaucoma
Progression of Disease in Patients Newly Diagnosed With Glaucoma and Glaucoma Suspects Participating in the GATE Study
The purpose of this study is to measure how many patients develop worsening glaucoma in the early years (2-4 years) of routine monitoring in hospital eye services.
- Trial name
- PEG (NCT03394521)
- Testing
- Routine clinical practice
- Volunteers
- 326 people
- Sponsor
- University of Aberdeen
Glaucoma, Glaucoma Suspect
Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study
The goal is to conduct a 5-year prospective, randomized controlled trial to test an innovative, community-based intervention using posterior and anterior fundus photography of the optic nerve and macula and intraocular eye…
- Conditions
- Glaucoma, Glaucoma Suspect, Diabetic Retinopathy, Ocular Hypertension
- Trial name
- NCT02390245
- Testing
- Free Eye Screenings, Enhanced Intervention, Usual Care
- Where
- United States
- Volunteers
- 906 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Ocular Hypertension
Study of ST266 Given by Intranasal Delivery in Glaucoma Suspect Subjects
The primary objective of this trial is to assess the safety of ST266 given by non-invasive intranasal trans-cribriform delivery to glaucoma suspect subjects with ocular hypertension, optic nerve cupping, or family history of…
- Trial name
- NCT03901781
- Testing
- ST266 via Intranasal Delivery
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Glaucoma
Anterior Chamber Angle Examination in Angle Closure Suspect Patients
The aim of this study is to detect PACG suspects using both AS OCT and Scheimpflug imaging.
- Trial name
- NCT05209204
- Testing
- ASOCT, Pentacam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Glaucoma, Open Angle, Low Risk
Effect of Negative Pressure on Pattern Electroretinography Readings
Glaucoma is a leading cause of blindness worldwide. Intraocular pressure (IOP) remains the only modifiable risk factor for glaucoma.
- Conditions
- Glaucoma, Open Angle, Low Risk, Ocular Hypertension, Glaucoma Suspect
- Trial name
- NCT04433702
- Testing
- Mercury™ Multi-Pressure Dial (MPD) Experimental Goggle
- Where
- United States
- Sponsor
- Vance Thompson Vision
Ocular Hypertension, Suspect Glaucoma
Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects
The goal of this clinical trial is to compare participants treated with latanoprost to those treated with Rocklatan (netarsudil/latanoprost) to determine whether the addition of netarsudil results in greater improvements in…
- Trial name
- NCT04401982
- Testing
- Rocklatan (Netarsudil 0.02%/ latanoprost 0.005), Latanoprost (0.005%)
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Glaucoma Suspect
Water Drinking Test and Its Reproducibility in Goldmann Applanation Tonometry and Pneumatic Tonometry
The purpose of this study is to evaluate the reproducibility of tonometry in the Goldmann applanation apparatus and pneumatic in the water drinking test.
- Trial name
- WDTRGP (NCT03014349)
- Testing
- Analysis of medical records
- Volunteers
- 100 people
- Sponsor
- VER Excelência em Oftalmologia
Glaucoma
Glaucoma Laser Assessment of Stability and Sustainability
The GLASS Study is designed to help researchers learn whether repeating a non-invasive laser treatment called DSLT (Direct Selective Laser Trabeculoplasty) can better control eye pressure in patients with early-stage glaucoma or…
- Trial name
- GLASS (NCT06963684)
- Testing
- Dual-Treatment Direct Selective Laser Trabeculoplasty (DSLT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Twin Cities Eye Consultants
Glaucoma, Glaucoma, Suspect
Automated Applanation Tonometry
Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability.
- Trial name
- NCT05235321
- Testing
- Standard GAT, Fixed force GAT, Upright applanating prototype
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Duke University
Primary Angle Glaucoma Closure Suspect
Danish Angle Closure Prevention Trial
To determine whether primary angle closure suspects (PACS) in a Caucasian population benefit from prophylactic laser iridotomy.
- Trial name
- DAP (NCT06077253)
- Testing
- Iridotomy
- Where
- 5 sites in Denmark
- Volunteers
- 242 people
- Sponsor
- University of Aarhus
Normal Tension Glaucoma, Primary Open-angle Glaucoma
Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl
This study is for patients have been using prostaglandin analogue eye drops with a preservative for 3 months or more and have been diagnosed with prostaglandin-associated peri-orbital disease.
- Conditions
- Normal Tension Glaucoma, Primary Open-angle Glaucoma, Glaucoma, Suspect, Ocular Hypertension
- Trial name
- NOPAPS (NCT05279716)
- Testing
- Eybelis ophthalmic solution 0.002%
- Where
- 8 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Santen Pharmaceutical Asia Pte. Ltd.
Glaucoma, Suspect, Glaucoma
Validation of an Automatic Analysis Algorithm of the Probability of Glaucoma From Optic Disc Images
Clinical, cross-sectional and prospective study to assess the images of the posterior pole of the retina of patients from the Glaucoma Unit of the IOBA and the Hospital Clínico Universitario de Valladolid during the period…
- Conditions
- Glaucoma, Suspect, Glaucoma, Ocular Hypertension
- Trial name
- NCT04972695
- Testing
- Fundus Photographs (retinographies)
- Where
- Spain
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Glaucoma, Glaucoma, Suspect
Automated Applanation Tonometry - Updated
Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability.
- Trial name
- NCT07298356
- Testing
- Standard GAT, Fixed force GAT, Upright applanating prototype
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Glaucoma, Ocular Hypertension
A Phase I Clinical Trial of DARC
Glaucoma is a major cause of irreversible blindness worldwide, caused by retinal nerve cell (RGC) death. This is currently identified only after significant vision loss has already occurred with an early event in, and a potential…
- Conditions
- Glaucoma, Ocular Hypertension, Glaucoma, Suspect
- Trial name
- NCT02394613
- Testing
- ANX776
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University College, London
Glaucoma
SENSIMED Triggerfish Safety and Tolerability
The purpose of this investigation is to study the safety and tolerability of SENSIMED Triggerfish, a soft contact lens-based device intended to continuously record relative changes in intraocular pressure (IOP).
- Trial name
- NCT01319617
- Testing
- SENSIMED Triggerfish
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Sensimed AG
Glaucoma
Stop Retinal Ganglion Cell Dysfunction Study
Glaucoma is a progressive disease resulting in blindness. Determining the onset of the disease, predicting its severity and the benefit of pressure lowering eye drops is key to clinical management aimed at maintaining useful…
- Trial name
- STOP-RGCD (NCT02390284)
- Testing
- Latanoprost, Bimatoprost, Travoprost
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma
Comparison of SITA-Standard Compared to SITA-Fast Visual Fields.
This study will compare SITA-Standard and SITA-Fast tests in patients newly referred to the glaucoma screening clinic at the RD\&E hospital.
- Trial name
- NCT03192085
- Testing
- SITA FAST VISUAL FIELD TEST, SITA STANDARD VISUAL FIELD TEST
- Volunteers
- 150 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust