Clinical trials: Glaucoma
Glaucoma, Retinal Disease
The EASE Study - Human Factor and Usability Testing of a Binocular OCT System
Ophthalmology is among the most technology driven of all medical specialties, with advanced medical imaging devices - and specialised computer software - increasingly adopted for routine clinical use.
- Conditions
- Glaucoma, Retinal Disease, Strabismus, Healthy Volunteers
- Trial name
- EASE (NCT02822612)
- Testing
- Binocular OCT prototype
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University College, London
Healthy Subjects
SENSIMED Triggerfish® in Sitting and Supine Position
The purpose of the study is to evaluate changes in intraocular pressure (IOP) between sitting and supine body positions and correlate the values obtained with conventional tonometers to the output provided by the investigational…
- Trial name
- NCT01347229
- Testing
- SENSIMED Triggerfish®
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Healthy
Effect of Topical Glaucoma Therapy on Tear Film Stability in Healthy Subjects
Long term treatment with anti-glaucomatous drugs has been shown to increase the incidence of dry eye syndrome with all known consequences such as ocular discomfort and epithelial keratitis.
- Trial name
- NCT01746602
- Testing
- Timoptic® 0.5%, Timophtal sine® 0.5%, Genteal HA®
- Where
- Austria
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Glaucoma
Spectralis OCT Repeatability and Reproducibility Study
This single-center, prospective, interventional clinical study is conducted to evaluate the repeatability and reproducibility of structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the…
- Trial name
- S-2013-1 (NCT02209077)
- Testing
- OCT performed to collect data from the back of the eye
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Glaucoma
The Water Drinking Test in Glaucoma Study
To investigate the correlation and agreement between the intraocular pressure peaks detected during the water drinking test and modified diurnal tension curve in glaucomatous eyes and to analyse whether this is associated with…
- Trial name
- WIGS (NCT05283031)
- Testing
- Modified Diurnal Tension Curve
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Glaucoma, Open-angle
The Effectiveness of YAG Iridotomy in Preventing Peripheral Anterior Synechia After CLASS in Primary Open Angle Glaucoma
To investigate the effectiveness of YAG laser iridotomy in preventing peripheral anterior synechia after CO2 Laser-Assisted Sclerectomy Surgery and the long-term effect of reducing intraocular pressure
- Trial name
- NCT04912362
- Testing
- YAG iridotomy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Glaucoma
Discriminating Ability of the Cirrus High Definition (HD) Optical Coherence Tomography (OCT) for Glaucoma
The Cirrus HD OCT, a new spectral domain optical coherence tomography, has better resolution than the previous OCT. Reproducibility and discriminating ability of the Cirrus HD OCT for glaucoma detection will be studied.
- Trial name
- NCT00742378
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Glaucoma
ICare Self-tonometry - A Head-to-head Comparison to the Gold Standard Goldmann Tonometer
The purpose of this study is to compare glaucoma patients' own I Care measurements by the standard Goldmann applanation tonometer intraocular pressure (IOP) measurements.
- Trial name
- NCT01733550
- Testing
- Home iCare (study nurse), goldmann applanation tonometry, home iCare (by patient)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Glaucoma
Fixating the Plate of Ahmed Valve to the Sclera Using a Flanged Prolene Suture
this study evaluated new technique for suturing the Ahmed valve device used to treat resistant types of glaucoma
- Trial name
- NCT06722794
- Testing
- Novel Technique for Fixating the Plate of Ahmed Valve to the Sclera Using a Single Flanged Prolene Suture
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Open Angle Glaucoma, Normal Tension Glaucoma
Study on the Oxygen Saturation in Pulsating and Non-pulsating Central Retinal Veins
Retinal ischemia is thought to play an important role in the pathogenesis of glaucoma. Recent findings have confirmed that there is a direct correlation between the levels of venous oxygen saturation and the degree of the…
- Trial name
- NCT01794442
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Eye Disease, Eye Care
Tailored Messages to Increase Eye Examination Behavior
The purpose of this project is to test two different types of health messages, one that is developed for a specific group (targeted) and the other that is more personalized to individuals (tailored), to see which is better at…
- Trial name
- NCT00649766
- Testing
- tailored newsletter, targeted newsletter
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Optic Neuropathy
Biomechanics of Optic Neuropathy
The participant is being asked to be a subject in this research study because the participant may have a disorder that can cause optic nerve damage and impairment of his/her visual function which is called optic neuropathies…
- Trial name
- NCT02982499
- Testing
- magnetic resonance image (MRI), Optical Coherence Tomography (OCT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma, Rubeosis Iridis
Intravitreal Aflibercept or Ranibizumab for Rubeosis Iridis
Aflibercept (Eylea®) and ranibizumab (Lucentis®) are an anti-VEGF, but there are differences between the two drugs. To determine and compare whether intraocular aflibercept and ranibizumab decreases rubeosis iridis (RI) in…
- Trial name
- NCT02641457
- Testing
- Aflibercept, Ranibizumab
- Where
- Brazil
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma
Malay Glaucoma Eye Study II Navigation, Mobility and Reading Ability in Primary Glaucoma
With the improvement of health system, the life span of Asians has increased tremendously especially in Malaysia. As an early preparation to be an 'aging country' in 2023, Malaysia needs to prepare infrastructure and policy to…
- Trial name
- MaGESII (NCT04736264)
- Testing
- Visual rehabilitation module: navigation and mobility, Visual rehabilitation module: exercise, Visual rehabilitation module: reading
- Where
- Malaysia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Primary Open Angle Glaucoma
The Effects of Visior on Ocular Hemodynamics
To determine the relationship between the affects of viewing commercially available content through the VISIOR video goggles and ocular blood flow in glaucoma patients and healthy subjects.
- Trial name
- NCT02959593
- Testing
- VISIOR video goggles
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Visior Technologies Ltd.
Glaucoma
Evaluation of a Novel Head-Mounted Device for Glaucoma Testing: A Proof-of-Concept Study
This proof-of-concept study aims to determine the feasibility and effectiveness of using a custom head-mounted device for visual field testing.
- Trial name
- NCT05030714
- Testing
- Visual Field Testing
- Where
- 2 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brennan Eadie
Vision Impairment and Blindness, Glaucoma
Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice
In this cohort study, the investigators will test vision screenings in Danish general practice for patients over 70 years of age with minimum one chronic condition.
- Conditions
- Vision Impairment and Blindness, Glaucoma, Age-Related Macular Degeneration, Cataract
- Trial name
- DETECT (NCT07015034)
- Testing
- focus on vision impairment in older patients in general practice
- Where
- 2 sites in Denmark
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Glaucoma, Myopia
Efficacy of Retinal Nerve Fiber Layer (RNFL) / Retinal Thickness Ratio by Cirrus OCT Utilizing Spectral -Domain Technology as a Diagnostic Predictor of Glaucoma
Glaucoma is presumed to be an axonal disease which starts at the lamina cribrosa. This assumption has led to the monitoring of the retinal nerve fiber layer thickness for the diagnosis and monitoring of progression of glaucoma.
- Trial name
- NCT00772993
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Glaucoma, Retinal Vein Occlusion
Study of the Retinal Vascularization by Laser Doppler Velocimetry Coupled With an Adaptive Optics Camera ( AO-LDV)
The difficulty to measure blood flow in humans is connected with the necessity of using not invasive, reliable and reproducible techniques.
- Trial name
- AO-LDV (NCT03525132)
- Testing
- Laser Doppler Velocimetry + Optic Adaptative Camera
- Where
- France
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Visual Field Defect, Peripheral
Virtual Reality Visual Field Testing as an Alternative in Childhood Eye Disease
The purpose of this study is to test a new way of measuring the peripheral vision (called a visual field test) using a device which can be worn as goggles rather than being a large instrument the patient must sit at.
- Trial name
- NCT05150197
- Testing
- VisuALL, Humphrey Visual Field
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University