Clinical trials: Glaucoma Diagnosis
Glaucoma
Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-3)
This prospective, single-arm clinical multicenter study intends to measure normal structural parameters of the optic nerve head, the peripapillary retinal nerve fiber layer, and the macula using the Heidelberg Spectralis OCT…
- Trial name
- NCT02785042
- Testing
- Heidelberg Spectralis OCT
- Where
- 8 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Glaucoma, Ocular Hypertension
A Phase 1, Open-Label Study of Latanoprost Acid Plasma Concentrations in Pediatric and Adult Glaucoma Patients Treated With Latanoprost.
To evaluate the steady-state systemic plasma concentrations of latanoprost acid following administration of latanoprost 0.005% (1.5 ug) in pediatric and adult subjects with glaucoma or ocular hypertension.
- Trial name
- NCT00638742
- Testing
- latanoprost
- Where
- 13 sites in United States, Denmark and 4 more
- Volunteers
- 47 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Glaucoma, Ocular Hypertension
An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension
This efficacy and safety study will evaluate LUMIGAN® RC/ LUMIGAN® .01 (bimatoprost 0.01%) alone compared to TRAVATAN Z® (travoprost 0.004%) and TIMOLOL MALEATE-EX, 0.5%/TIMOLOL GFS 0.5% (timolol 0.5% ophthalmic gel forming…
- Trial name
- NCT01881126
- Testing
- bimatoprost 0.01%, travatan 0.004%, timolol 0.5%
- Where
- 2 sites in Canada
- Volunteers
- 93 people
- Sponsor
- Allergan
Congenital Glaucoma
Study Aim to Compare the Effect of Different Technique of Airway Managment During Anaesthesia on the Haemodynamics and Intraocular Pressure. Patients Were Divided Into Three Groups of 25 Patients Each. (Group A); Patients Who Were Subjected to LMA Insertion (Group B ).
this study aim to compare the effect of different technique of airway managment during anaesthesia on the haemodynamics and intraocular pressure in pediatric patient undergoing congenital glaucoma surgery.
- Trial name
- Airway and IOP (NCT07504315)
- Testing
- laryngeal mask insertion, I gel mask insertion, Endotracheal tube insertion
- Volunteers
- 75 people
- Sponsor
- Sohag University
Glaucoma, Cataract
Comparative Study of the Cornea/Anterior Segment OCT CASIA2 and the RTVue XR OCT Avanti With AngioVue Software
This study is a prospective comparative, randomized, single center study to gather agreement and precision data in all subjects.
- Trial name
- NCT04486976
- Testing
- Cornea/Anterior Segment OCT CASIA2, Optovue RTVue XR Avanti
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Tomey Corporation
Glaucoma, Age Related Macular Degeneration
Assessment of Visual Function With a Portable Brain-computer Interface
1. The purpose of this study is to evaluate the nGoggle's accuracy and repeatability in detecting visual function loss. In addition, the ability to stage glaucomatous damage and investigate the relationship between nGoggle…
- Conditions
- Glaucoma, Age Related Macular Degeneration, Optic Neuropathy, Retinal Degeneration
- Trial name
- NCT03760055
- Testing
- nGoggle
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NGoggle
Glaucoma,Open-Angle, Ocular Hypertension (OH)
Transscleral Selective Laser Trabeculoplasty Project
The purpose of this clinical trial is to determine how safe and effective (how well it works) the ELLEX TSLT device is for the treatment of Glaucoma and Ocular Hypertension using Transscleral Selective Laser Trabeculoplasty.
- Trial name
- TSLT project (NCT06833060)
- Testing
- Selective Laser Trabeculoplasty
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Lumibird Medical (Quantel Medical, Ellex Medical, Optotek)
Primary Open Angle Glaucoma, Ocular Hypertension
Ph2 Placebo-Controlled Study for Safety & Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Pts w/ Elevated Eye Pressure
The goal of this clinical trial is to test in patients with glaucoma and elevated pressure in the eye. The main questions it aims to answer are: • ability to lower pressure in the eye • safety in the eye and the body of patients…
- Trial name
- NCT06144918
- Testing
- SBI-100 Ophthalmic Emulsion, 0.5%, SBI-100 Ophthalmic Emulsion, 1.0%
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Skye Bioscience, Inc.
Glaucoma, Ocular Hypertension
6-Week Proof-of-Concept Study of Travoprost/Brinzolamide Ophthalmic Suspension in Subjects With Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to evaluate Travoprost/Brinzolamide fixed combination (Trav/Brinz) administered twice daily as compared to each of its marketed components (TRAVATAN Z® solution and AZOPT® suspension) and to the…
- Trial name
- NCT02140060
- Testing
- Dose Level A / Brinzolamide 1% ophthalmic suspension, Dose Level B / Brinzolamide 1% ophthalmic suspension, Dose Level C / Brinzolamide 1% ophthalmic suspension
- Volunteers
- 327 people
- Sponsor
- Alcon Research
Open-Angle Glaucoma
Efficacy of Surgical Systems in Combination With Phacoemulsification: a Retrospective Analysis
Real-World efficacy of Hydrus Microstent with OMNI Surgical System in combination with Phacoemulsification: a retrospective analysis
- Trial name
- NCT06953349
- Testing
- Real-World efficacy of Hydrus Microstent with OMNI Surgical System in combination with Phacoemulsification: a retrospective analysis
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Barnet Dulaney Perkins Eye Centers
Glaucoma
Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma
To evaluate the effect of brimonidine tartrate 0.025% on conjunctival hyperemia in patients treated with netarsudil 0.02%/latanoprost 0.005% mono-therapy for intraocular pressure lowering.
- Trial name
- NCT07209410
- Testing
- Brimonidine Tartrate Ophthalmic 0.025%
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,
Glaucoma, Retinal Disease
OCT Agreement and Crossed Precision Study
The purpose of this study is to asses the agreement of the RS-3000 Lite and RS-3000 Advance to the RS-3000, assess the crossed precision of each study device and to assess the transference of a reference database from the RS-3000…
- Conditions
- Glaucoma, Retinal Disease, Corneal Disease
- Trial name
- NCT02050880
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Glaucoma
The Role of Music in Enhancing Attention During Visual Field Exams for Pediatric Glaucoma Patients
The goal of the study is to see if the use of music improves attention during visual field exams for pediatric glaucoma patients.
- Trial name
- NCT06971588
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Johns Hopkins University
Glaucoma, Primary Open Angle
Glaucoma Assessment Via Reading Ability
To explore a quantitative glaucoma evaluation tool of glaucoma through the dynamic evaluation of reading ability based on logarithmic Chinese reading acuity chart (C-READ), and investigate its feasibility.
- Trial name
- NCT05673954
- Testing
- C-Read test
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University
Primary Open Angle Glaucoma (POAG), Ocular Hypertension (OHT)
REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension
This study will test an experimental drug called REGN22530 ("study drug") to see if it can help treat people with primary open angle glaucoma or ocular hypertension.
- Trial name
- BAHAMA (NCT07675824)
- Testing
- REGN22530
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- Regeneron Pharmaceuticals
Primary Open-angle Glaucoma, Ocular Hypertension
A Clinical Study to Evaluate the Efficacy and Safety of CKD-351
The purpose of this study is to evaluate efficacy and safety of CKD-351.
- Trial name
- NCT03762369
- Testing
- CKD-351, Latanoprost, D930
- Where
- South Korea
- Volunteers
- 384 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Ocular Hypertension, Primary Open Angle Glaucoma
A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
This is a single-center, cross-over comparison parallel group randomized trial designed to evaluate the efficacy and safety of Ganfort compared to Duotrav for a treatment period of 8 weeks each.
- Trial name
- NCT01168414
- Testing
- Ganfort, Duotrav
- Where
- Malaysia
- Volunteers
- 42 people
- Sponsor
- Ministry of Health, Malaysia
Glaucoma, Ocular Hypertension
Neurovascular Coupling in Eyes of Glaucoma Patients
We hypothesize that glaucoma patients demonstrate an impaired retinal vascular response to the flicker stimulus, and that this disturbance is predictive of the progression of glaucomatous damage.
- Trial name
- NCT00429819
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland
Primary Open Angle Glaucoma
Vision Preservation and Restoration Following a 6 Month Trial of GlaucoCetin
This study is looking at changes in vision and visual function before and after a six month trial of a daily medical food called GlaucoCetin, formulated with ingredients to support and protect the optic nerve cells.
- Trial name
- NCT04784234
- Testing
- GlaucoCetin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wills Eye
Open-angle Glaucoma, Ocular Hypertension
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00314171
- Testing
- Brinzolamide 10 mg/ml + Timolol 5 mg/ml eye drops, suspension, Dorzolamide 20 mg/ml + Timolol 5 mg/ml eye drops, solution (COSOPT)
- Volunteers
- 437 people
- Sponsor
- Alcon Research
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