Clinical trials: Glaucoma Surgery
Glaucoma Eye
An Innovation in Glaucoma Surgery: XEN45 Gel Stent Implantation
Purpose: To report the follow-up data for patients who had XEN45 gel stent implantation, a new method of minimally invasive glaucoma surgery (MIGS).
- Trial name
- NCT03138928
- Testing
- XEN45 gel stent implantation in glaucoma surgery
- Volunteers
- 15 people
- Sponsor
- Trakya University
Glaucoma, Glaucoma Surgery
Vienna Preserflo Cohort Study
The Vienna Preserflo Microshunt Cohort Study is an observational study with a prospective postoperative examination in all glaucoma patients who had received a Preserflo Microshunt (PMS) as standalone procedure or in combination…
- Conditions
- Glaucoma, Glaucoma Surgery, Post-Op Complication, Efficacy, Self
- Trial name
- NCT04541524
- Testing
- Santen Preserflo Microshunt
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Medical University of Vienna
Intraocular Pressure, Open Angle Glaucoma
A FIH Trial of the STREAMLINE™ SURGICAL SYSTEM
The purpose of this study is to evaluate the safety and Intraocular pressure lowering effectiveness of the Streamline™ Surgical System.
- Trial name
- NCT04700189
- Testing
- ab interno canaloplasty
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- New World Medical, Inc.
Glaucoma, Open-Angle, Cataract
Results of Patients With Glaucoma Undergoing Minimally Invasive Glaucoma Surgery in Conjunction With Cataract Surgery
This study is designed to determine how well patients with glaucoma can see following cataract surgery with a special type of lens called an extended-depth-of-focus (EDOF) lens.
- Trial name
- NCT05624398
- Testing
- Vivity IOL
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vold Vision P.L.L.C
Lenses, Intraocular, Glaucoma Filtration Implants
Visual Function and Patient Satisfaction in Glaucoma or Ocular Hypertensive Patients Undergoing Simultaneous Cataract Surgery and i-Stent Implantation
New extended depth of focus intraocular lenses (IOLs) are being used in a broader spectrum of patients than trifocal IOLs. The purpose of this study is to evaluate visual improvement after cataract surgery in patients with…
- Trial name
- NCT05392738
- Testing
- I-Stent implantation
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Clínica Rementería
Glaucoma
A Comparison Between Deep Sclerectomy and Trabeculectomy
Patients affected by medically uncontrolled open angle glaucoma will be randomised to either a non penetrating procedure (deep sclerectomy) or conventional trabeculectomy. The longterm efficacy (i.e.
- Trial name
- NCT00595855
- Testing
- trabeculectomy, deep sclerectomy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Parma
Glaucoma
Efficacy and Safety of the ELIOS Laser in Combined Cataract and Glaucoma Surgery
Glaucoma is an irreversible optic neuropathy. It is the second most common cause of blindness worldwide. Glaucoma can be treated with topical medications (eye drops), laser or surgery.
- Trial name
- ELIOS (NCT06760169)
- Testing
- Surgery with ELIOS laser
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Hôpital Privé de la Baie
Glaucoma
Does Adding Bevacizumab Therapy in Glaucoma Surgery Improve the Success of Needle Bleb Revisions?
The purpose of this study is to see if a new add on (or adjunctive) therapy used in glaucoma surgery improves the success of needle bleb revisions.
- Trial name
- Avastin (NCT00853073)
- Testing
- bevacizumab, balanced salt solution
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Wills Eye
Glaucoma
A Trial of China Laser and Surgery Study Glaucoma in Rural China
Aims and Objectives (Quantitative) Aim: To compare the effectiveness of selective laser trabeculoplasty with trabeculoplasty in lowering the intraocular pressure in patients with medically uncontrolled open angle glaucoma in…
- Trial name
- NCT02955849
- Testing
- SLT laser
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Glaucoma
Dexmedetomidine as an Additive to Local Anaesthesia to Decrease Intraocular Pressure in Glaucoma Surgery
Nowadays, a number of cases with increased intraocular pressure and glaucoma have been shown a huge increase . This is because of the increase the geriatric population in the community and advanced medical care.
- Trial name
- NCT02846090
- Testing
- Dexmedetomidine to reduce the IOP
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Cairo University
Glaucoma
A First-In-Human Clinical Trial to Evaluate the Safety, Effectiveness and Surgical Characteristics of CADENCE in Patients With Refractory Glaucoma
To evaluate safety, effectiveness, and the surgical performance of CADENCE in patients with refractory glaucoma.
- Trial name
- NCT05131087
- Testing
- Cadence implant
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- New World Medical, Inc.
Glaucoma, Open-Angle
A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System
The purpose of this study is to evaluate the long-term safety and effectiveness of the OMNI® Surgical System in subjects who were treated under protocol #06213
- Trial name
- NCT05044793
- Testing
- OMNI® Surgical System
- Where
- 4 sites in United States
- Volunteers
- 70 people
- Sponsor
- Sight Sciences, Inc.
Glaucoma
Study on Micro-invasive Glaucoma Surgical (MIGS) Devices
Glaucoma is an ocular condition in which optic nerve damage occurs, frequently in the presence of increased pressure within the eye.
- Trial name
- NCT04092400
- Testing
- Micro-invasive Glaucoma Surgical Devices
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- National University Hospital, Singapore
Glaucoma, Canaloplasty
Trabeculectomy Versus Canaloplasty
Study aims for comparison of trabeculectomy and canaloplasty, in order to find out if one operation is superior to the other. Both procedures are performed in patients with medically uncontrolled open-angle glaucoma.
- Conditions
- Glaucoma, Canaloplasty, Trabeculectomy
- Trial name
- TVC (NCT01228799)
- Testing
- trabeculectomy, Canaloplasty
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- University Eye Hospital, Würzburg
Primary Glaucoma
eyeWatch vs. Trabeculectomy RCT (evT)
The confirm the performance and safety of the eyeWatch System as first-line filtering surgery and compare its outcomes to trabeculectomy
- Trial name
- evT (NCT04323930)
- Testing
- eyeWatch
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Dr. Kaweh Mansouri
Glaucoma, Primary Open Angle
Excimer Laser Trabeculostomy Glaucoma Treatment Study
Evaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG) undergoing cataract surgery
- Trial name
- ELTGTS (NCT04899063)
- Testing
- ELIOS Procedure
- Where
- 20 sites in United States
- Volunteers
- 318 people
- Sponsor
- Elios Vision, Inc.
Glaucoma
Eye Pressure Lowering Surgery
The purpose of this study is to determine if lowering the pressure inside the eye improves blood flow to the eye.
- Trial name
- IOP (NCT01931904)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Oregon Health and Science University
Glaucoma
Outflow Facility AIT vs Microshunt
The purpose of this study was to asses differences in nycthemeral (24-h) intraocular pressure (IOP) profiles and outflow facilities between patients who have undergone epibulbar microshunt implantation and ab interno…
- Trial name
- NCT05548959
- Testing
- Pneumatonometry after microshunt implantation, Pneumatonometry after ab interno trabeculectomy
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- Wuerzburg University Hospital
Open-angle Glaucoma
Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost
Evaluation of the intraocular pressure (IOP) lowering effect of two iStent devices versus medical therapy in eyes of subjects with primary open-angle glaucoma, pseudoexfoliative glaucoma, or ocular hypertension naïve to medical…
- Trial name
- NCT01443988
- Testing
- iStent, Travoprost
- Where
- Armenia
- Volunteers
- 101 people
- Sponsor
- Glaukos Corporation
Glaucoma
The Use of Bevacizumab as a Modulator of Wound Healing Following Trabeculectomy Surgery
This is a phase III randomised controlled pilot study which aims to assess the effectiveness of the use of bevacizumab in patients who have undergone trabeculectomy surgery, which appear to be showing early signs of failure.
- Trial name
- RAFTS (NCT02767219)
- Testing
- bevacizumab, 5-fluorouracil, Dexamethasone
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust