Clinical trials: Global Surgery
Postoperative Pain
Effect of Noise Isolation on the Incidence of Moderate to Severe Postoperative Pain
To investigate the effect of noise isolation during general anesthesia on the incidence of moderate to severe postoperative pain in patients undergoing major abdominal surgery.
- Trial name
- NCT06316440
- Testing
- Wear noise-cancelling earphones
- Where
- China
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
General Surgery, Costs and Cost Analysis
Evaluating the Impact of the National Health Insurance Scheme of Ghana on Surgical Care
Ghana, a Low-Middle Income Country (LMIC) situated in the heart of West Africa started a national health insurance scheme in 2003.The scheme was designed to provide a comprehensive benefit package inclusive of surgical care and…
- Trial name
- NCT03604458
- Where
- Ghana
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Hyperoxemia, Intraoperative Oxygen Therapy
Oxygen Reserve Index-Guided Oxygen Titration During Surgery in the Beach Chair Position
This study aims to evaluate whether guidance by the Oxygen Reserve Index (ORi) improves inspiratory oxygen fraction (FiO₂) titration compared with conventional pulse oximetry (SpO₂)-guided oxygen administration in adult patients…
- Conditions
- Hyperoxemia, Intraoperative Oxygen Therapy, Beach Chair Position, Cerebral Oxygenation
- Trial name
- ORI-BCP (NCT07404267)
- Testing
- ORi-Guided FiO₂ Titration, SpO₂-Guided FiO₂ Titration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Anesthesia, Anorectal Surgery
Spinal Anesthesia Versus General Anesthesia Using Laryngeal Mask Airway for Anorectal Surgeries in Prone Position
Anorectal surgeries are of the commonest elective surgeries that are performed worldwide under different types of anaesthesia. The aim of this prospective interventional study was to compare the use of general anaesthesia (GA)…
- Trial name
- NCT04214977
- Testing
- Spinal Anesthesia for Anorectal Surgeries in Prone Position, General Anesthesia Using Laryngeal Mask Airway for Anorectal Surgeries in Prone Position
- Where
- Jordan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Pain, Stress
Evaluation Of The Analgesia Nociception Index vs. Surgical Pleth Index Under General And Regional Anaesthesia
There is a lack of sufficient analgesia monitoring apart from surrogate parameters. The analgesia nociception index (ANI) shall be evaluated under general and regional anaesthesia.
- Conditions
- Pain, Stress, Monitoring
- Trial name
- NCT02744573
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Total Knee Arthroplasty
Effect of Different Cold Therapy Programs in Patients Received Total Knee Arthroplasty Operation
This study conducts clinical experiments on the form, temperature, frequency and other issues of cooling therapy, so as to provide scientific evidence for the practice of cooling therapy and improve the comfort and effect of…
- Trial name
- NCT07021287
- Testing
- mixed ice and water, continuous ice application, mixed ice and water, intermittent ice compress, full ice, continuous ice compress
- Where
- 2 sites in China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Elderly Patients, Laparoscopic Surgery
Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery
This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia…
- Conditions
- Elderly Patients, Laparoscopic Surgery, Postoperative Hypoxemia, Capnography
- Trial name
- NCT07652385
- Testing
- EtCO₂ Monitoring, Routine Monitoring
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Hernia, Incisional Hernia
"Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and Laparoscopic
"Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias, diaphragmatic hernias, diaphragmatic rupture…
- Trial name
- 36P (NCT02137018)
- Testing
- PPL fixation by BP, PPL mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Electroencephalography, General Anesthesia
Multi-center Isoelectric EEG Study in Children Under General Anesthesia
Multi-center, prospective, observational study investigating the incidence of isoelectric electroencephalography (EEG) events and the associated peri-operative factors in infants 0-3yo undergoing general anesthesia.
- Conditions
- Electroencephalography, General Anesthesia, Pediatric Anesthesia
- Trial name
- NCT03432351
- Where
- 15 sites in United States, Australia and 3 more
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Surgical Education
Global Learning: an Orbis Virtual-platform Evaluation Study
Currently, surgical training is often conducted using the traditional "apprentice model", where a trainee observes a qualified surgeon and learns from him/her, and then the surgeon supervises the trainee performing surgery on a…
- Trial name
- GLOVES (NCT04908072)
- Testing
- Orbis-FundamentalVR MSICS Simulator
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Orbis
Idiopathic Normal Pressure Hydrocephalus
Gait Pattern and Experienced Global Change After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Part 1 Patients with idiopathic Normal Pressure Hydrocephalus (iNPH) have variable disabilities regarding gait, balance, cognition and continence.
- Trial name
- NCT04795089
- Testing
- Shunt surgery
- Where
- Sweden
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Neoplasms
A Randomized Controlled Trial of a Robotic Simulation Curriculum to Teach Robotic Suturing
The aim of this study is to determine if training with a robotic simulator improves ability to perform robotic suturing. We aim to recruit 38 participants (attending surgeons or residents in obstetrics and gynecology, urology…
- Trial name
- NCT01811095
- Testing
- Training
- Where
- 2 sites in Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- McGill University
Verapamil, Diltiazim
Efficacy of Oral Verapamil and Oral Diltiazim on Reduction of Intraoperative Bleeding During Endoscopic Sinus Surgery Under General Anesthesia
To study the effect of addition of oral verapamil or Diltiazim to general anaesthesia on the Intraoperative haemodynamics : heart rate(HR), noninvasive blood pressure(NIBP), mean arterial blood pressure(MAP), and the blood loss…
- Conditions
- Verapamil, Diltiazim, FESS
- Trial name
- NCT04790331
- Testing
- Verapamil, Diltiazem
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Difficult Intubation in Obstructive Sleep Apnea
Ultrasound Versus Clinical Tests as Predictors of Difficult Endotracheal Intubation in Patients With Obstructive Sleep Apnoea Undergoing Elective Surgery Under General Anaesthesia
Obstructive sleep apnoea (OSA) is the most serious kind of the sleep-disordered breathing group, characterised by recurrent episodes of partial to complete obstruction of the upper airway resulting in inefficient alveolar gas…
- Trial name
- NCT05402683
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tanta University
Global Surgery, Health System
Surgical Assessment Tool for Ethiopia National Policy Monitoring & Evaluation
Introduction: A baseline assessment of surgical capacity is recommended as a first-step to inform national policy on surgical system strengthening.
- Conditions
- Global Surgery, Health System, Health Planning, Global Anesthesia
- Trial name
- NCT04276103
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
General Anesthesia
Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia
To demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous [IV] slow injection over 30 [±5] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection…
- Trial name
- NCT05478174
- Testing
- HSK3486, Propofol
- Where
- 23 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Generalized Chronic Periodontitis
Erbium Chromium: YSGG Laser Effect on Surgical Treatment of Chronic Periodontitis
Microbiological and Clinical assessment of Er,Cr:YSGG laser in conjunction to open flap debridement (OFD) in treatment of chronic periodontitis through real time PCR assay for quantification of total bacterial load.
- Trial name
- NCT03810560
- Testing
- laser device Er,Cr:YSGG laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- alaa
Stress, Physiological, Stress, Psychological
Impact of Music in the Preoperative Stress of Children Undergoing General Surgery
Preoperative anxiety and stress are present in up to 60% of pediatric patients undergoing surgery, having a great physiological and emotional impact on children in both the short and long term.
- Trial name
- NCT02947919
- Testing
- Music
- Where
- Chile
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Supraglottic Airway Devices
Respiration and The Airway With Laryngeal Masks
Baska® mask (Proact Medical Systems, Frenchs Forest NSW, Australia) is displayed in figure 1 which is the latest addition to an array of supra-glottic airway devices in clinical use.
- Trial name
- NCT03542890
- Testing
- Baska Mask, I-gel
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Global Surgery, Global Health
Google Trends of Global Surgery
Introduction Global surgery is a growing movement worldwide, but its expansion has not been quantified. Google Search is the most popular search engine worldwide, and Google Trends analyzes its queries to determine popularity…
- Trial name
- NCT05012085
- Testing
- Investigation of Global Interest in Global Surgery
- Where
- Cameroon
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Association of Future African Neurosurgeons, Yaounde, Cameroon