Clinical trials: Global Surgery
Post Operative Pain
Efficacy of Parecoxib Combined With Paracetamol in Mastectomy
Patients undergoing breast cancer surgery experience persistent pain after surgery and subsequent development of chronic pain. Parecoxib or paracetamol has been reported to reduce postoperative pain in mastectomy.
- Trial name
- NCT05757388
- Testing
- Parecoxib + paracetamol, Normal saline
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Khon Kaen University
Postoperative Pain, Psychological Factors
Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
This study investigates the relationship between psychosocial factors, particularly self-esteem and personality traits, and postoperative pain in patients undergoing aesthetic breast surgery.
- Conditions
- Postoperative Pain, Psychological Factors, Breast Surgery, Aesthetic Surgery
- Trial name
- NCT06707818
- Testing
- Preoperative Interventions, Intraoperative Interventions, Postoperative Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Wounds
Octylseal Surgical Adhesive in General Surgery
The purpose of this study is to evaluate how surgical adhesive is used.
- Trial name
- NCT01514383
- Testing
- Cyanoacrylate (Octylseal )
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Medline Industries
Nausea and Vomiting, Postoperative
The Role Of Laserpuncture For Prevention Of Nausea And Vomiting Post Strabismus Surgery With General Anesthesia In Adult Patients
This study to determine the effectiveness of a combination of pre-surgical laserpuncture with standard anti-emetic therapy for PONV symptoms in adult patients after strabismus surgery under general anesthesia compared to a…
- Trial name
- NCT06302673
- Testing
- Laserpuncture
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Breast Cancer
Added Conversational Hypnosis Reduced General Anesthesia Side Effects for Day Case Breast Surgery
Evaluate the impact of the support in reducing postoperative adverse events in particular on the pain but also on anxiety, comfort, nausea, vomiting, and fatigue.
- Trial name
- HYPNOSEIN (NCT03253159)
- Testing
- Hypnosis
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Evaluation, Outpatient Surgery
Out-patient Discharge Management After General Intravenous Anesthesia
The lower limit of time for postoperative observation and discharge criteria for diagnostic or operational tests program in outpatient under general intervenous anesthesia/sedation
- Trial name
- NCT05609383
- Testing
- assessment
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Gynecologic Surgical Procedures, Urologic Surgical Procedures
Study of Atelectasis by Electrical Impedance Tomography
The goal of this interventional study is to learn about the effects of different positions on the occurrence, regional distribution and reversibility of atelectasis by using a PulmoVista 500 monitor (Dräger.
- Trial name
- NCT05713929
- Testing
- Recruitment maneuver (RM), Reverse Trend (REV TREND)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Erasme University Hospital
Sleep Disordered Breathing
Oxygen Monitoring of Patients After Surgery on the Hospital General Care Floor
The pain medication given after major surgery may cause some patients to stop breathing for periods of time especially at night time. An oxygen monitor may reflect this abnormal breathing pattern.
- Trial name
- NCT01082575
- Testing
- Oxygen Monitoring
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Kasai Operation, Biliary Atresia
The Comparison of Desflurane and Sevoflurane on Postoperative Recovery and Hepatic Function of Biliary Atresia Patients During Kasai Operation
Biliary atresia (BA) is a perinatal disease of unclear etiology, characterized by inflammation and obliteration of intrahepatic and extrahepatic bile ducts, leading to cholestasis and cirrhosis.
- Trial name
- NCT01443572
- Testing
- desflurane anesthetics, sevoflurane anesthetics
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Anesthesia, Surgery
Frontal Electroencephalography of Neonatal Patients Under Sedation With Opioids and General Anesthesia With Propofol.
Frequently, neonates hospitalized in neonatology units require anesthesia for surgery. The drugs used for this purpose are opioids and other anesthetics, such as propofol.
- Conditions
- Anesthesia, Surgery, Neonate, Depth of Anesthesia
- Trial name
- NCT04904965
- Testing
- Propofol Group 1, Propofol Group 2, Propofol Group 3
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Herniated Disk Lumbar
Lumbar Spine Surgery: Regional vs. General Anaesthesia
Background: Lumbar spine surgery can be performed using different anaesthetic techniques such as general endotracheal anaesthesia (GA) or spinal-based regional anaesthesia (RA), that have different side effect profiles (e.g.
- Trial name
- NCT03300089
- Testing
- General anaesthesia, Regional anaesthesia
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- St. Anna Clinic Luzern
Analgesia
Efficacy and Safety of HSK21542 in Inducing Postoperative Analgesia in Undergoing Elective Laparoscopic Surgery
This is a multicenter, randomized, double-blind, placebo-controlled, two-stage phase II clinical study. The main objective is to evaluate the efficacy and safety of HSK21542 injection and explore the recommended dose and…
- Trial name
- NCT04424251
- Testing
- Experimental: stage I:HSK21542 0.4 μg/kg, Experimental: stage I:HSK21542 1 μg/kg, Experimental: stage I:HSK21542 0.5μg/kg
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Gastrointestinal Malignancies
Predictive Value of NRS2002 and GLIM for Complications After GI Malignancy Surgery
This prospective cohort study investigates and compares the predictive power of two nutritional assessment tools, the Nutritional Risk Screening 2002 (NRS2002) and the Global Leadership Initiative on Malnutrition (GLIM) criteria.
- Trial name
- NCT07104175
- Where
- China
- Volunteers
- 471 people
- Sponsor
- Third central hospital of Tianjin affiliated Nankai university
Anesthesia, General
Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)
The primary purpose of the study is to determine the time-course of recovery to a T4/T1 ratio of 0.9 within 4 minutes after 4.0 mg.kg^-1 Sugammadex is administered at least 15 minutes after the last administration of rocuronium…
- Trial name
- NCT00298831
- Testing
- Sugammadex, Rocuronium
- Volunteers
- 224 people
- Sponsor
- Merck Sharp & Dohme LLC
Tympanoplasty Surgery, Laryngeal Mask Airway
Comparative of Video Laryngeal Mask and Endotracheal Intubation in Patients Undergoing Tympanoplasty Surgery.
The effects of video laryngeal mask and endotracheal intubation on hemodynamic parameters and the development of postoperative respiratory complications in participants scheduled for tympanoplasty will be evaluated.
- Trial name
- NCT07084636
- Testing
- Video Laryngeal Mask, Endotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Samsun University
General Surgery
Incidental Findings in Abdominal Surgery
Despite the recent advancement in diagnostic modalities, many surgeons experience till this day unexpected findings during the course of surgery.
- Trial name
- NCT05227911
- Testing
- Abdominal Surgery
- Where
- Syria
- Volunteers
- 543 people
- Sponsor
- University of Aleppo
Periodontitis Chronic Generalized Severe, Intrabony Periodontal Defect
Clinical and Radiograhic Evaluation of NIPSA With and Without Allograft Plus Platelet Rich Fibrin in the Treatment of Intraosseous Defects in Stage III Periodontitis Patients
Several minimal invasive techniques have been proposed since the last decade aiming to enhance and provide adequate environment for periodontal regeneration.
- Trial name
- NCT04444063
- Testing
- Non-Incised Papilla Surgical Approach
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Complications of Surgical and Medical Care: General Terms
a New Way for Laparoscopic Inguinal Hernia Repair in Pediatric
laparoscopic hernia sac high-ligation has a high recurrence rate laparoscopic hernia sac high-ligation and the lateral umbilicus ligament covering the hernia opening The investigators developed a method of laparoscopic hernia…
- Trial name
- NCT01380067
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of GuangDong Province
Total Knee Arthroplasty
Effect of Different Cold Therapy Programs in Patients Received Total Knee Arthroplasty Operation
This study conducts clinical experiments on the form, temperature, frequency and other issues of cooling therapy, so as to provide scientific evidence for the practice of cooling therapy and improve the comfort and effect of…
- Trial name
- NCT07021287
- Testing
- mixed ice and water, continuous ice application, mixed ice and water, intermittent ice compress, full ice, continuous ice compress
- Where
- 2 sites in China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Major Abdominal Surgery
Albumin Kinetics in Generalized Inflammation
The purpose of this study is to determine whether the kinetics of endogenous albumin is altered by the generalized inflammation caused by major abdominal surgery.
- Trial name
- NCT01194492
- Testing
- Albumin transcapillary escape rate (125I-albumin)
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
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