Clinical trials: Global Surgery
Intraoperative Awareness, Intraoperative Responsiveness During General Anesthesia
Evaluation of Intraoperative Awareness and Its Correlation With Processed EEG Biomarkers During Laparoscopic Surgery
This prospective observational cohort study aims to evaluate intraoperative responsiveness and possible intraoperative awareness in adult patients undergoing elective laparoscopic abdominal surgery under general anesthesia and to…
- Trial name
- NCT07831590
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Duzce University
Resident Education
Coding Improvement Project: Resident Education on Documentation
Most General Surgery program directors have expressed the necessity to educate residents on the business aspect of medicine. However, the literature review did not produce any interventional studies directly addressing coding and…
- Trial name
- DER (NCT04538196)
- Testing
- Resident education on documentation and coding
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Colorectal (Colon or Rectal) Cancer, STOMACH NEOPLASM
Perioperative Biomarkers in Colorectal and Gastric Cancer Surgery
This study aims to evaluate whether monitoring perioperative inflammatory and metabolic biomarkers can help identify postoperative complications early in adult patients undergoing colorectal or gastric cancer surgery.
- Trial name
- PERIO-BIO (NCT07881133)
- Testing
- Perioperative Biomarker-Guided Monitoring
- Where
- Romania
- Volunteers
- 320 people
- Sponsor
- Bucharest Emergency Hospital
Pleural Effusion
Comparison of Thoracoscopic Talc Pleurodesis by Thoracic Epidural or General Anesthesia
Video-assisted thoracoscopic surgery (VATS) talc pleurodesis is often carried out in patients with malignant recurrent pleural effusion to relieve symptoms and prevent recurrence.
- Trial name
- NCT01469728
- Testing
- Non-awake VATS talc pleurodesis, Awake VATS talc pleurodesis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Obesity
Comparison of Acceleromyography and Electromyography in Obese Patients Undergoing General Anesthesia
The goal of this prospective observational study is to compare two different methods of monitoring muscle relaxation during anesthesia - acceleromyography (AMG) and electromyography (EMG) - in people with obesity who are having…
- Trial name
- OBAEG (NCT07283354)
- Testing
- Neuromuscular monitoring with electromyography (EMG), Neuromuscular monitoring with acceleromyography (AMG)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Padova
General Anesthesia
Effect of Sevoflurane and Propofol on Hepato-splanchnic Pressure and Flow During Hepatobiliary Surgery
Blood loss in hepatobiliary surgery is correlated with an increase in postoperative complications (e.g. transfusion related lung injury and tumor recurrence) and reduced longterm survival.
- Trial name
- NCT03772106
- Testing
- Propofol Fresenius, sevorane
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- University Hospital, Ghent
Cardiopulmonary Arrest
Extension of Rapid Response Team Operation Time and Cardiopulmonary Resuscitation Incidence
Although early rapid response team was reported as a full-time operating system, similar efficacy of part-time rapid response team has been recently reported.
- Trial name
- NCT05712915
- Testing
- RRT operation
- Where
- South Korea
- Volunteers
- 142,088 people
- Sponsor
- Dong-A University Hospital
Acute Pain, Chronic Pain
ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY
The main aim of our study was to test the hypothesis that Erector spine plane block (ESP) with sedation will provide the similar employment of fentanyl and propofol during surgery as an infiltrative local anaesthesia with…
- Conditions
- Acute Pain, Chronic Pain, Postoperative Pain, Anesthesia
- Trial name
- NCT05483647
- Testing
- Local infiltrative anaesthesia, Erector spine plane block
- Where
- Ukraine
- Volunteers
- 52 people
- Sponsor
- Lviv National Medical University
Supratentorial Brain Tumor Surgery
FASt Track in Elective Neurosurgery: the Role of Low Propofol Bis-NOL Guided General Anaesthesia for Full, Early and Safe Awakening
To evaluate the effect of intraoperative sedation dosage on awakening and recovery of consciousness after elective neurosurgical surgery.
- Trial name
- FasTrack (NCT06844838)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Anesthesia, Surgery
The Effect of Two Different General Anesthesia Regimes on Postoperative Sleep Quality
Major surgery can lead to postoperative disturbances in sleep patterns with subjective deterioration of sleep quality according to patients' reports as well as objective alterations of sleep architecture, as recorded by…
- Conditions
- Anesthesia, Surgery, Sleep Disorders
- Trial name
- NCT02061514
- Testing
- maintenance with desflurane, maintenance with propofol
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Aretaieion University Hospital
Myocardial Injury
Effects of Remimazolam on Postoperative Myocardial Injury
This study is designed as a prospective, double-blind, randomized controlled trial to investigate the effect of remimazolam on intraoperative cardiac output (CO) in elderly patients undergoing general anesthesia, and to evaluate…
- Trial name
- NCT07725185
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Jiaxing University
IOP Changes Due to Anesthesia (Healthy Patients)
The Effect of Different Sevoflurane Concentrations on Intraocular Pressure in Patients Undergoing Ocular Surgery Under General Anesthesia
One important goal in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP). An increase in IOP may be catastrophic in patients with glaucoma or a penetrating open-eye injury.
- Trial name
- NCT01575626
- Testing
- Sevoflurane
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Anesthesia
The Effect and Mechanism of Respiratory Stimulant Doxapram on Facilitating Emergence
The current study is designed to investigate the difference of plasma orexin A levels between doxapram group and controlled group at emergence time from sevoflurane-remifentanil anesthesia who will undergo elective lumbar surgery.
- Trial name
- NCT02820025
- Testing
- doxapram, saline
- Where
- China
- Volunteers
- 40 people
- Sponsor
- General Hospital of Ningxia Medical University
Pain, Postoperative
Caffeine and Neurologic Recovery Following Surgery and General Anesthesia
The ongoing opioid epidemic is a public health crisis, and surgical patients are particularly vulnerable to opioid-dependency and related risks. Emerging data suggest that caffeine may reduce pain after surgery.
- Trial name
- NCT03577730
- Testing
- Caffeine Citrate, Dextrose Water
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Michigan
General Anesthesia, Elective Laparoscopic Cholecystectomy
The Effect of Positive End-Expiratory Pressure Levels on Perfusion Index and Neurocognitive Functions in Geriatric Patients
With the increasing geriatric population, age-related physiological changes and common comorbidities increase the risk of surgical and anesthesia-related complications in this patient group.
- Trial name
- NCT07505550
- Testing
- PEEP levels
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Ankara City Hospital Bilkent
Airway Ultrasound
Airway Ultrasound As an Independent Predictor of Difficult Laryngoscopy in Patients Receiving General Anesthesia for Elective Surgery
The goal of this observational study is to determine the usefulness of pre-operative airway ultrasound in predicting difficult laryngoscopy in patients receiving general anesthesia for elective surgery.
- Trial name
- NCT06391840
- Testing
- Airway ultrasound
- Where
- Greece
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- DIMITRIOS KATSAROS
Chronic Pain Post-Procedural
Block REducing Pain After Surgery Trial
This observational study evaluates difference in chronic pain after six months from surgery between patients who received PECS block and general anesthesia versus general anesthesia alone.
- Trial name
- BREAST (NCT03448913)
- Testing
- PECS block
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- University of Padova
Gynecological Laparoscopic Surgery, General Anesthetic
Effects and Safety of Oliceridine in Anesthesia Induction:A Randomised Controlled Trial
to investigate whether oliceridine is safe and effective for induction of anesthesia by comparing henodynamic changes before and after endotracheal intubation with sufentanil
- Conditions
- Gynecological Laparoscopic Surgery, General Anesthetic, Intubation
- Trial name
- NCT07372209
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tangshan Maternal and Child Health Hospital
Menopause, Overweight
Epidemiology of Urinary Functional Disorders in Women of 40 and More
Assess prevalence of urinary functional disorders in women of 40 and more, visiting a general practitioner, occupational medicine or health examination center in Puy-de-Dôme.
- Conditions
- Menopause, Overweight, Surgical Antecedent, Gestity
- Trial name
- NCT03586765
- Testing
- Female urinary incontinence
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.