Clinical trials: Global Surgery
Anesthesia; Reaction, Adverse Effect of Other General Anesthetics
Influence of Anesthesia Technique on Postoperative Evolution After Urogenital Surgical Interventions
The study hypothesis is that regional anesthesia offers better outcome for the patients who underwent robot assisted laparoscopic urogenital surgery.
- Conditions
- Anesthesia; Reaction, Adverse Effect of Other General Anesthetics, Adverse Anesthesia Outcome, Acute Kidney Injury
- Trial name
- ROBOTNGAL (NCT01898897)
- Testing
- epidural catheter insertion, robot assisted laparoscopic urogenital surgery
- Where
- Romania
- Volunteers
- 60 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Laparoscopic Surgery
Response Surface Modeling of Remimazolam and Sevoflurane
This prospective randomized open-label study aims to investigate the pharmacodynamic interaction between remimazolam and sevoflurane during general anesthesia using response surface modeling.
- Trial name
- NCT07620782
- Testing
- Remimazolam (Byfavo), Sevoflurane (Volatile Anesthetic)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Pusan National University Yangsan Hospital
Airway Management, Tracheal Intubation
Effect of Night Shift Versus Daytime Duty on Tracheal Intubation Complications and Duration in Surgical Patients
Airway management is one of the most critical steps of anesthesia, and its complications can be life-threatening. Reduced staffing, differences in personnel experience, and physical and mental fatigue during off-hours (evenings…
- Conditions
- Airway Management, Tracheal Intubation, Intubation Complications, General Anesthesia
- Trial name
- NCT07823179
- Testing
- Tracheal Intubation
- Volunteers
- 1,000 people
- Sponsor
- Merve Yazici Kara
Smoking, Smoking Cessation
Intervention for Smoking Cessation in Pre-Surgical Patients.
The goal of this clinical trial is to assess efficacy of an intensive pre-surgical intervention to quit smoking in smoking patients who will be operated on implant orthopedic surgery or general and urological surgery.
- Conditions
- Smoking, Smoking Cessation, Surgical Procedure, Unspecified
- Trial name
- NCT05961813
- Testing
- Intensive intervention for smoking cessation, Brief intervention for smoking cessation
- Where
- Spain
- Volunteers
- 232 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
General Anesthesia
Echocardiographic Findings and 30-days Outcomes for Intraventricular Conduction Delay in Patients Undergoing Elective Surgeries
The purpose of this study is to investigate the type of the cardiac disease using transthoracic echocardiography in patients whose preoperative electrocardiography shows the intraventricular conduction delay.
- Trial name
- NCT02718313
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Kidney Stones, Nephrolithiasis
Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery
This randomized clinical trial will compare four ventilation strategies during retrograde intrarenal surgery performed under general anesthesia.
- Trial name
- RIRS-VENT (NCT07705646)
- Testing
- Standard Ventilation, Hypoventilation, Intermittent Apnea Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Anesthesia, Intubation
Impact of Extubation Location After Surgery on Perioperative Times
The additional time required to awaken a patient is one of the main reasons for not extubating him or her in the operating room (OR).
- Conditions
- Anesthesia, Intubation, Surgery, Extubation
- Trial name
- Extub_Loca (NCT06249659)
- Testing
- Extubation in operative room, Extubation in post anesthesia care unit
- Where
- France
- Volunteers
- 756 people
- Sponsor
- University Hospital, Clermont-Ferrand
Elective Surgical Patient, Hypertensive Patients
Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients
Dexmedetomidine, an alpha-2 adrenergic agonist, has been shown to provide several benefits during endotracheal intubation: 1. _Reduced anxiety and stress_: Dexmedetomidine's anxiolytic and sedative effects help reduce anxiety and…
- Conditions
- Elective Surgical Patient, Hypertensive Patients, Blood Pressure, Hypertensive Elderly Patients
- Trial name
- NCT06712186
- Testing
- Dexmedetomidine Group / Group D
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Ventral Hernia, Umbilical Hernia
Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
Ventral hernias can be repaired using a variety of techniques, with smaller defects often being amenable to minimally invasive surgical (MIS) approaches.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia
- Trial name
- NCT04150796
- Testing
- Ventral Hernia Repair
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Heart Disease
Assessment of Cardiac Function and Anesthesia Depth in Patients Undergoing Cardiac Surgery
The SHAPE study is a prospective, randomized study evaluating changes in cardiac function in adult patients undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- SHAPE (NCT07770269)
- Testing
- BIS-guided anesthesia: BIS 45-55, BIS-guided anesthesia: BIS 30-35
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- AHEPA University Hospital
Anesthesia
Anesthesia for Emergency Orthopedic Surgery
The aim of this retrospective study is to evaluate the preferred anaesthesia techniques in our clinic for emergency orthopedic surgery at a 1 year period.
- Trial name
- NCT02820922
- Testing
- Orthopedic
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sakarya University
Oral Dryness, General Surgery
Evaluation of Safety and Efficacy of Using Lipsus Device for Oral Wetting
Following waking up from surgery performed under general anesthesia, patients are suffering from discomforting oral dryness, and moreover, they are not allowed drinking for 24 hours.
- Trial name
- NCT00945022
- Testing
- wetting lips following surgery using anesthesia
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- IMD Tech Ltd
Postoperative Delirium
The Comparison of Incidence and Risk Factors of Postoperative Delirium in Elderly Patients After Lower Extremity Surgery
The aim of this study is to compare the risk factors and the incidence of delirium following orthopedic surgery under the general or regional anesthesia in elderly patients.
- Trial name
- NCT02360982
- Testing
- propofol and esmeron(rokuronyum), marcaine and fentanyl
- Volunteers
- 120 people
- Sponsor
- Cukurova University
Preoperative Anxiety
The Effect of Anaesthesia Technique on Anxiety in Upper Extremity Surgery Patients
This prospective, cross-sectional study aims to investigate the impact of planned anesthesia technique (general or regional anesthesia) and patients' previous anesthesia experience on preoperative anxiety in patients undergoing…
- Trial name
- NCT06667596
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Obesity
Comparison of Acceleromyography and Electromyography in Obese Patients Undergoing General Anesthesia
The goal of this prospective observational study is to compare two different methods of monitoring muscle relaxation during anesthesia - acceleromyography (AMG) and electromyography (EMG) - in people with obesity who are having…
- Trial name
- OBAEG (NCT07283354)
- Testing
- Neuromuscular monitoring with electromyography (EMG), Neuromuscular monitoring with acceleromyography (AMG)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Padova
Venous Thromboembolism, Bleeding
Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial
Avoiding Risks of Thrombosis and bleeding in Surgery (ARTS) trial is a pragmatic, international, multicenter, randomized controlled open label trial comparing a direct oral anticoagulant (DOAC) - oral factor Xa inhibitor apixaban…
- Trial name
- ARTS (NCT06523959)
- Testing
- Apixaban 2.5 MG
- Where
- Finland
- Volunteers
- 5,436 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Thyroidectomy
Superficial, Cervical Block in Thyroid Surgery, a Randomized Controlled Trial
The study investigates the impact on post-operative pain of the superficial cervical block with bupivacaine combined with subcutaneous infiltration of the incisional area in thyroid surgery under general anesthesia.
- Trial name
- NCT00472446
- Testing
- bilateral superficial cervical block
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- Cantonal Hospital of St. Gallen
Laryngoscopic Stress Response, Video Laryngoscopy
Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics
In general anestheisa airway is secured by passing a tube down the widpipe. This helps the patient to breath via ventilator during anesthesia.
- Conditions
- Laryngoscopic Stress Response, Video Laryngoscopy, Conventional Laryngoscopy
- Trial name
- NCT07300878
- Testing
- C MAC hyperangulated video laryngoscopy, Conventional macintosh laryngoscopy
- Where
- Pakistan
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems
A Comparative Study of CCI, EmSFI, and FTRST Scoring Systems
Frailty assessment tools and comorbidity indices play a crucial role, particularly in predicting outcomes for elderly patients undergoing emergency surgery.
- Conditions
- One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems, Gastrointestinal Neoplasms, Appendicitis Acute
- Trial name
- NCT06943924
- Testing
- Frailty assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Postoperative Myocardial Ischemia
Evaluation of a Model for Post-Anesthesia Troponin Increase and Heart Injury EStimation
This study evaluates the preoperative cardiovascular risk, the intraoperative hemodynamic characteristics and the surgical photo-plethysmographic index of patients undergoing general anesthesia for non-cardiac vascular surgery to…
- Trial name
- EMPATHIES (NCT03375476)
- Testing
- collection of cardiovascular risk scores and intraoperative cardiovascular parameters, cardiac troponin assay, Electrocardiogram
- Where
- Italy
- Volunteers
- 117 people
- Sponsor
- ASST Fatebenefratelli Sacco
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