Clinical trials: Global Surgery
Pain, Stress
Evaluation Of The Analgesia Nociception Index vs. Surgical Pleth Index Under General And Regional Anaesthesia
There is a lack of sufficient analgesia monitoring apart from surrogate parameters. The analgesia nociception index (ANI) shall be evaluated under general and regional anaesthesia.
- Conditions
- Pain, Stress, Monitoring
- Trial name
- NCT02744573
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Resident Education
Coding Improvement Project: Resident Education on Documentation
Most General Surgery program directors have expressed the necessity to educate residents on the business aspect of medicine. However, the literature review did not produce any interventional studies directly addressing coding and…
- Trial name
- DER (NCT04538196)
- Testing
- Resident education on documentation and coding
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
General Surgery, Blood Loss, Surgical
Intraoperative Estimated Blood Loss, Blood Transfusion, and Postoperative Clinical Outcomes in Patients Undergoing Non Cardiac Surgery, Siriraj Hospital
After review literature, Siriraj hospital has not unanimous protocol to guide proper preoperative anemia and blood transfusion. This retrospective study will review non-cardiac surgery cases and collect data such as demographic…
- Trial name
- NCT05430659
- Testing
- observational study
- Where
- Thailand
- Volunteers
- 1,268 people
- Sponsor
- Siriraj Hospital
Ankle Sprains, Instability, Joint
The Clinical Outcomes of the Arthroscopic and Open Modified Broström Operation in CLAI and GJL
Investigators designed this randomized controlled trial to compare the clinical outcomes of open and arthroscopic modified Broström operation for the treatment of CLAI and GJL.
- Conditions
- Ankle Sprains, Instability, Joint, Joint Hypermobility
- Trial name
- NCT05284188
- Testing
- Open or arthroscopic Modified Broström operation
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Peking University Third Hospital
Surgery, Postoperative
Temperature Measurement in Post-Anesthesia Care Units
This study will evaluate the accuracy of several thermometers and temperature changes during surgery and immediately after surgery.
- Conditions
- Surgery, Postoperative, Laparoscopic Surgery, General Anesthesia
- Trial name
- NCT00614588
- Testing
- Body temperature thermometers
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Intra Ocular Hypertension
The Effect of Two Different Artificial Respiration Methods on the Intraocular Pressure During Surgery Under General Anesthesia
The purpose of this study is to examine whether the intraocular pressure of operated people under general anesthesia is affected by the artificial respiration method.
- Trial name
- NCT01567761
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Trachea Intubation
Surgical Pleth Index: Predicting the Optimal Timing for Tracheal Intubation During General Anesthesia
Surgical pleth index (SPI) has been widely investigated in assessing the nociceptive level, and tracheal intubation is a noxious stimulus during the induction of anesthesia.
- Trial name
- NCT04608240
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Fudan University
Tracheal Intubation, Videolaryngoscopy
Video Versus Direct Laryngoscopy for Tracheal Intubation in Pediatric Surgery
Tracheal intubation in paediatric patients is a high-risk procedure in which failure to achieve successful intubation on the first attempt is associated with an increased risk of complications, including hypoxaemia and airway…
- Conditions
- Tracheal Intubation, Videolaryngoscopy, General Anesthesia, Difficult Airway Intubation
- Trial name
- VIDEOKIDS (NCT07495436)
- Testing
- Videolaryngoscope, Direct Laryngoscope
- Where
- Spain
- Volunteers
- 5,562 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Inflammation, Anesthesia
Effect of Anesthesia Method on Neutrophil-Lymphocyte Ratio
The neutrophil/lymphocyte ratio (NLR) is a simple and inexpensive marker of the inflammatory response. NLR is affected not only by surgical trauma but also by the anesthetic method.
- Trial name
- NCT05628935
- Testing
- peripheral nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Zonguldak Bulent Ecevit University
Analgesia
Comparison of Standard Epidural and Dural Puncture Epidural Analgesia in Open Gynecological Surgery Techniques
The aim of this study is to compare the effectiveness of standard epidural and dural puncture epidural analgesia techniques used under NOL guidance.
- Trial name
- NCT05408052
- Testing
- Dural Puncture Epidural (DPE), Standart Epidural
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Oxygenation
Obesity, PEEP and Postoperative Oxygenation
A study on overweight patients undergoing anesthesia for laparoscopic surgery. evaluation of positive end-expiratory pressure versus zero positive end-expiratory pressure during awakening on oxygenation in the early postoperative…
- Trial name
- ZAPPAII (NCT04150276)
- Testing
- ZEEP during awakening, PEEP during awakening
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Västmanland
Anesthesia, Preoxygenation
Preoxygenation Before General Anesthesia
Rationale of the study: we aim to clarify the question (related to still unclear and not univocal response) about the protective or unnecessary role of preoxygenation in non-critically ill patients (otherwise with no high risk of…
- Trial name
- PREOX2018 (NCT03802643)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Parma
Abdominal Surgery, General Anesthesia
Effect of Reflective Blanket on Undesirable Perioperative Hypothermia
The aim of this study is to determine the effect of using reflective blankets, which is a passive insulation product, on preventing UPH in patients scheduled for abdominal surgery under general anesthesia.
- Conditions
- Abdominal Surgery, General Anesthesia, General Surgery
- Trial name
- NCT05702320
- Testing
- the heating procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Öğr. Gör. Ali GÜZEL
Coronary Artery Disease, Cardiac Autonomic Neuropathy
IMPACT OF CARDIAC AUTONOMIC NEUROPATHY ON QT AND QTC INTERVAL
This prospective observational cohort study evaluated the effect of cardiac autonomic neuropathy (CAN) on perioperative ventricular repolarization, specifically QT and corrected QT (QTc) intervals, in patients undergoing elective…
- Conditions
- Coronary Artery Disease, Cardiac Autonomic Neuropathy, QT Interval Prolongation
- Trial name
- QT interval (NCT07684768)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Elderly Patients, Laparoscopic Surgery
Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery
This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia…
- Conditions
- Elderly Patients, Laparoscopic Surgery, Postoperative Hypoxemia, Capnography
- Trial name
- NCT07652385
- Testing
- EtCO₂ Monitoring, Routine Monitoring
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Continuous Positive Airway Pressure, Hypoxia
Positive Pressure at Induction of Anesthesia in Children
SCENARIO: Hypoxemia is one of the most common adverse events during the induction of general anesthesia and may culminate with more serious complications such as cardiac arrest and death.
- Conditions
- Continuous Positive Airway Pressure, Hypoxia, General Anesthesia
- Trial name
- NCT03432390
- Testing
- Continuous Positive Airway Pressure, Open system ventilation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Hyperglycemia
Sitagliptin in Non-Diabetic Patients Undergoing General Surgery
The purpose of this study is to compare sitagliptin with a placebo for the prevention of high glucose after general surgery.
- Trial name
- NCT02741687
- Testing
- Sitagliptin, Supplemental insulin (insulin lispro), Supplemental insulin (insulin aspart)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Emory University
General Anaesthesia During Pregnancy
Intelligence and Neurodevelopmental Disorders After Prenatal Exposure to General Anaesthesia
Every year in the European Union, thousands of babies are exposed to anaesthesia before they are born because their mothers need surgery during pregnancy.
- Trial name
- PAE-IQ (NCT06633406)
- Testing
- Age-appropriate Wechsler Intelligence Test, Disruptive Behavior Disorders Rating Scale, Social Responsiveness Scale
- Where
- 3 sites in Belgium
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Type 2 Diabetes
Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 Diabetes
The purpose of this study is to try and achieve similar glycemic control in general non-Intensive Care Unit (non-ICU) patients with Type 2 Diabetes with exenatide alone or in combination with basal insulin as compared to…
- Trial name
- NCT02455076
- Testing
- Exenatide, Glargine, Rapid-acting insulin analogs
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University
Oral Intubation
GlideScope Video Laryngoscope Versus Fiberoptic Intubation
Following informed consent, patients will be randomly assigned to oral fiberoptic intubation or to oral intubation using the GlideScope Video Laryngoscope.
- Trial name
- NCT01091948
- Testing
- Intubation with Fiberoptic laryngoscope, GlideScope® Video Laryngoscope
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Cleveland Clinic
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