Clinical trials: Global Surgery
Pain, Surgery
The Impact of SCN9A Gene Polymorphism on Individual Pain Perception in the General Population
This study was conducted to explore whether the non-synonymous single-nucleotide polymorphisms in SCN9A gene can predict individual basal pain perception and postoperative pain intensity in the general population undergoing upper…
- Trial name
- NCT01507493
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xianwei Zhang
Obesity, Morbid
EPO2-A: Evaluation of Pre-Oxygenation in Morbid Obesity: Effect of Position and Positive Pressure Ventilation
The risk of complication associated with airway in obese patient is important. The result of pre-oxygenation gives the clinician a prolonged non-hypoxic apnea time.
- Trial name
- EPO2-A (NCT02590406)
- Testing
- Beach chair (BC) and ZEEP, Reverse Trendelenburg and NIPPV
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Laparoscopic Surgery, Medical Education
A Pilot Study on Training Simulator Efficacy
The purpose of this study is to plan an effective learning path in minimally invasive thoracic and general surgery with a virtual training simulator for trainees and to assess the improvement of residents' surgical skills by the…
- Conditions
- Laparoscopic Surgery, Medical Education, Simulation Training
- Trial name
- NCT05436899
- Testing
- LapSim training, LapSim exam
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Università degli Studi dell'Insubria
Hernia Abdominal Wall
Remifentanil in Deep vs Moderate Neuromuscular Blocks During Surgical Pleth Index-guided Anesthesia for Laparoscopic Herniorrhaphy
The primary purpose of this study is to compare the remifentanil requirements in deep versus moderate neuromuscular blocks during the surgical pleth index -guided anesthesia in patients undergoing laparoscopic herniorrhaphy.
- Trial name
- NCT04022733
- Testing
- Moderate neuromuscular block, Deep neuromuscular block
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Ajou University School of Medicine
Gynecology, Surgery
Novel Surgical Checklists for Gynecologic Laparoscopy in Haiti
The researchers traveled to University Hospital Mirebalais in Haiti and provided a one week long laparoscopic training and simulation course to the 7 OBGYN faculty there.
- Trial name
- NCT04059328
- Testing
- Surgical training
- Where
- Haiti
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Gender Issues
Gender Stigma Consciousness and Surgical Training
Previous investigations have focused on challenges that surgeons face once they have entered into practice. We have yet to explore difficulties in the training environment, and whether these have an effect on professional…
- Trial name
- NCT03623009
- Testing
- An article meant to trigger certain psychosocial behaviors, a neutral article
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Benign Tumor of Thyroid, Hyperparathyroidism
Bilateral Superficial Cervical Plexus Block in Thyroid/Parathyroid Surgery
To compare efficacy and safety between bilateral superficial cervical plexus block combined with intravenous sedation (RA group) and general anesthesia (GA group) for thyroid and parathyroid operations.
- Trial name
- NCT04051099
- Testing
- Bilateral superficial cervical plexus block with 0.25% bupivacaine 8 ml each (total 16 ml), Dexmedetomidine plus propofol infusion, Local infiltraion analgesia
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Preoxygenation, Anaesthesia
Quality of Preoxygenation in Emergency Surgery
Preoxygenation prior to general anaesthesia prolongs safe apnea time. Proper preoxygenation is always a challenge in emergency surgery.
- Conditions
- Preoxygenation, Anaesthesia, Emergencies, Surgery
- Trial name
- NCT04070404
- Where
- Lithuania
- Volunteers
- 200 people
- Sponsor
- Vilnius University
Cholecystitis
Video Laryngeal Mask Versus Endotracheal Tube Undergoing Laparoscopic Cholecystectomy Surgery
The aim of this study is to investigate the effectiveness of using a video laryngeal mask for airway management in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT06502028
- Testing
- Video laryngeal mask airway, Endotracheal tube
- Where
- South Korea
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hypothermia; Anesthesia
Forced Air and Intravenous Fluid Warmers in Gynecologic Laparoscopic Surgery
Perioperative hypothermia is a common problem. It has been defined as a core temperature below 36ºC. The reasons why patient undergoing gynecologic laparoscopic surgery has perioperative hypothermia because the reduced metabolic…
- Trial name
- NCT02990429
- Testing
- Forced Air warmer, Intravenous Fluid Warmer
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Siriraj Hospital
Preterm Infant, Anesthesia
The Comparison of Laryngeal Mask Airway and Endotracheal Tube in General Anesthesia for Premature Neonates
Objectives: To compare the perioperative respiratory adverse events between using laryngeal mask airway and endotracheal tube in preterm neonates receiving general anesthesia for hernia surgery.
- Conditions
- Preterm Infant, Anesthesia, Respiratory Complication
- Trial name
- NCT03931902
- Testing
- intubation with Endotracheal tube, intubation with laryngeal mask airway
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
General Surgery
Inflammation and Postoperative Tramadol Analgesia
Patients will be admitted in the intensive care unit after major abdominal surgery. All patients will receive 100 mg of tramadol intravenously every 6 hours.
- Trial name
- NCT04330157
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Arthroplasty, Replacement, Hip, Knee
Enhanced Recovery After Surgery (ERAS) Pathway for Primary Hip and Knee Arthroplasty
As the world goes into the aging society, the number of total hip and total knee arthroplasty (THA and TKA) will increase fast. It's important to develop strategies to improve the quality of healthcare and get earlier recovery…
- Trial name
- NCT03517098
- Testing
- The ERAS group, The non-ERAS group
- Where
- China
- Volunteers
- 640 people
- Sponsor
- West China Hospital
Regional Anesthesia, General Anesthesia
Monocyte Subsets Altered by Anesthesia
The impact of different anesthetic techniques on the immune system remains unclear. Aim of this ex vivo / in vitro study was to determine the effects of general and neuraxial anesthesia on monocyte subset alteration and the…
- Conditions
- Regional Anesthesia, General Anesthesia, Immune Function
- Trial name
- NCT03431532
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital, Saarland
Peritonitis, Sepsis
The Value of PSP in Predicting Outcome in ICU Surgical Peritonitis Patients
The purpose of this study is to determine the diagnostic accuracy of Pancreatic Stone Protein (PSP) in predicting patient outcomes with suspected peritonitis in the Intensive Care Unit after abdominal surgery and compare PPS with…
- Conditions
- Peritonitis, Sepsis, Multiple Organ Failure, Death
- Trial name
- NCT01465711
- Testing
- All abdominal surgical procedures, Intubation, Imaging
- Where
- Germany
- Volunteers
- 137 people
- Sponsor
- University of Magdeburg
Major Abdominal Surgery
Paravertebral Block vs. General Anesthesia for Major Abdominal Surgery
Elderly patients are usually presented with higher risk for developing cardiopulmonary complications after general anesthesia (GA).
- Trial name
- NCT02534012
- Testing
- Paravertebral block, General anesthesia, Major abdominal surgery
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Neuromuscular Blockade, Surgery
Effect of Neuromuscular Blockade on Operating Conditions and Overall Satisfaction During Spinal Surgery
The investigators aim to investigate operating conditions, postoperative recovery and overall satisfaction of surgeons between deep neuromuscular blockade (NMB) group and restricted NMB group during spinal surgery under general…
- Conditions
- Neuromuscular Blockade, Surgery, Anesthesia, Spinal Diseases
- Trial name
- NCT02724111
- Testing
- sufficient dose of rocuronium, sugammadex 10 min after position change
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Guro Hospital
Hypotension
Vasopressor Outcomes in Spine Surgery
This is a prospective, randomized control trial comparing norepinephrine versus phenylephrine for vasopressor support in patients undergoing elective spinal fusion surgery.
- Trial name
- V-SPINE (NCT06053398)
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Texas Southwestern Medical Center
Postoperative Residual Curarization, Neuromuscular Block
Reversal With Low Doses of Sugammadex in Patients Undergoing Non-cardiac Surgery
Neuromuscular blocking agents (NMBA) are among the most commonly used drugs during general anesthesia and may induce complete muscle paralysis.They are used clinically to facilitate endotracheal intubation and to optimize…
- Trial name
- NCT03460509
- Testing
- Sugammadex
- Volunteers
- 144 people
- Sponsor
- The Hospital of Vestfold
Laparoscopic Surgery, PONV
Effects of Auricular Acupressure on the Management of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgeries
Auricular acupressure is easily accessible and easily performed, and can significantly relieve PONV symptoms, and improve patient's satisfaction in women receiving general anesthesia for gynecological surgeries.
- Conditions
- Laparoscopic Surgery, PONV, Auricular Acupressure
- Trial name
- NCT05540236
- Testing
- auricular acupressure
- Where
- Taiwan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
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