Clinical trials: Global Surgery
Endoscopic Sinus Surgery, Heart Rate
Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic Sinus Surgery Under General Anaesthesia.
The study aims to compare the effect of addition of verapamil and Bisoprolol to general anasthesia aimed reduction in heart rate and blood loss during endoscopic sinus surgery.
- Conditions
- Endoscopic Sinus Surgery, Heart Rate, Blood Loss
- Trial name
- NCT04356196
- Testing
- Verapamil, Bisoprolol
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cerebral Autoregulation, Near-infrared Spectroscopy
Determination of Blood Pressure Limit of Cerebral Autoregulation During Non-cardiac Surgery in Preterm Infants, Neonates and Term Infants: a Prospective Observational Study Using Near-infrared Spectroscopy Monitoring
This prospective observational study aims to determine the blood pressure range in which cerebral autoregulation is maintained in preterm neonates, preterm infants, term neonates, and term infants undergoing non-cardiac surgery…
- Conditions
- Cerebral Autoregulation, Near-infrared Spectroscopy, Infant, Newborn, General Anesthesia
- Trial name
- NCT07660302
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Seoul National University Hospital
Breast Neoplasm, Prostate Neoplasm
Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care
The goal of this study is to investigate the effectiveness of a structured financial navigation program in reducing financial catastrophe and financial distress for cancer patients in Nigeria.
- Conditions
- Breast Neoplasm, Prostate Neoplasm, Colon Neoplasm, Rectal Neoplasm
- Trial name
- COST-FIN (NCT06630962)
- Testing
- Financial Navigation Program
- Where
- 2 sites in Nigeria
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Pediatric Surgical Procedures Requiring Endotracheal Intubation Under General Anesthesia
Comparison of Optimal Endotracheal Tube Depth Using Four Different Formulas in Children Aged 1-4 Years and Verification With Fiberoptic Bronchoscopy
. The optimal position of the endotracheal tube (ETT) within the trachea is the middle third portion, distal to the vocal cords.
- Trial name
- NCT06937840
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara University
Obesity, Obstructive Sleep Apnea
Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35
This study proposes to evaluate the clinical applicability of the ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA) in obese surgical patients undergoing general anesthesia.
- Trial name
- NCT01825278
- Testing
- ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Tufts Medical Center
Hypotension
TAPSE/PASP Anesthesia
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function.
- Trial name
- TAPSE/PASP (NCT06237543)
- Testing
- hypotension
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Aydin Adnan Menderes University
Clopidogrel
Does Continued Use of Clopidogrel Into Surgery Cause Increased Perioperative Bleeding?
Patients who on taking clopidogrel are randomized to either continue clopidogrel into general surgery or discontinue clopidogrel 7 days before surgery. All patients resume clopidogrel after surgery.
- Trial name
- NCT01960296
- Testing
- Clopidogrel, Discontinue Clopidogrel
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postoperative Pain, Ambulatory Surgery
Comparison Between Pre-operative Prescription Delivered During Anesthesia Consultation or Post-operative Prescription
This study evaluates the comparison of the incidence of postoperative home pain after ambulatory surgery with general anesthesia between a group with pre-surgical prescription delivered during anesthesia preoperative clinic and a…
- Conditions
- Postoperative Pain, Ambulatory Surgery, Anesthesia, Postoperative Complication
- Trial name
- AMBUPRESS (NCT03205189)
- Testing
- Comparison between pre-operative prescription and post-operative prescription
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Continuous Positive Airway Pressure, Hypoxia
Positive Pressure at Induction of Anesthesia in Children
SCENARIO: Hypoxemia is one of the most common adverse events during the induction of general anesthesia and may culminate with more serious complications such as cardiac arrest and death.
- Conditions
- Continuous Positive Airway Pressure, Hypoxia, General Anesthesia
- Trial name
- NCT03432390
- Testing
- Continuous Positive Airway Pressure, Open system ventilation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Postoperative Pain, Breast Cancer
Comparison of Erector Spinae Plane Block With Serratus Anterior Plane Block for Breast Surgery
Breast cancer is by far the world's most common cancer among women and the most common cause of female death from cancer worldwide. It's worldwide incidence is 43.4 in 100.000 while in Egypt is 48.8 in 100.000.
- Trial name
- NCT03579524
- Testing
- Erector Spinae Plane Block, Serratus Anterior Plane Block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Fayoum University Hospital
Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery
Effect of Subanesthetic Dose of Esketamine on Sleep Quality and Recovery of Gastrointestinal Function in Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery in the Early Postoperative Period
Patients undergoing gynecological surgery are at high risk of developing postoperative sleep disorders. Intraoperative opioid use is detrimental to the patient's postoperative recovery of gastrointestinal function.
- Trial name
- NCT05715671
- Testing
- esketamine
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Zhuan Zhang
Skin Sympathetic Nerve Activity During General Anesthesia in Patients Undergoing Breast Cancer Surgery
Measurement of the Skin Sympathetic Nerve Activity
Sympathetic nerve activity can be measured transcutaneously in awake patients by computer-based filtering of raw signal obtained via skin leads attached on the chest.
- Trial name
- NCT03658057
- Testing
- Rocuronium
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Morbid Obesity, Opioid-Related Disorders
Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients
This is an observational study of morbidly obese patients recovering from general anesthesia after weight-loss surgery. The investigators aim to assess ventilatory function and how this is influenced by the diagnosis of…
- Conditions
- Morbid Obesity, Opioid-Related Disorders, Surgery--Complications, Sleep Apnea Syndromes
- Trial name
- NCT03925610
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Nerve Block, General Anesthesia
Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.
The purpose of this study is to determine if there is a difference in patient outcomes with general anesthesia versus spinal anesthesia when given in addition to popliteal and adductor canal nerve blocks for foot and ankle…
- Conditions
- Nerve Block, General Anesthesia, Spinal Anesthesia, Pain
- Trial name
- LMA vs Spinal (NCT02996591)
- Testing
- 25 mL of 0.25% bupivacaine plus 2 mg preservative-free (PF) dexamethasone / 30 ml for popliteal nerve block, 10 mL of 0.25% bupivacaine plus 2 mg preservative-free (PF) dexamethasone / 30 ml for adductor canal nerve block, Midazolam, 2-5 mg IV + Glycopyrrolate, 0.1 mg IV + Ketamine, 10-20 mg + propofol as needed
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Hospital for Special Surgery, New York
Patients Undergoing Robotic Surgery
Quality of Recovery After Robotic Surgery
Robotic approach to laparoscopic surgery has greatly facilitated undertaking complex surgery inside the abdominal cavity with ease.
- Trial name
- NCT03659539
- Testing
- PROPOFOL, Desflurane
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Nitin Sethi, DNB
Surgical Procedures, Operative
Evaluation of Efficacy and Accuracy of a Cordless Ultrasonic Dissection System
The purpose of this study is to test the efficacy of a new cordless ultrasonic dissection system.
- Trial name
- SCUD (NCT01929928)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Wake Forest University Health Sciences
Education, Training
Trial of Proficiency- Based Simulation Training for General Surgical Trainees
The hypothesis of this trial is to demonstrate that training junior surgeons on a virtual reality (VR) simulator in addition to didactic teaching will improve their intraoperative performance compared to those trainees who…
- Conditions
- Education, Training, Computer Simulation
- Trial name
- NCT00712387
- Testing
- LapSim simulator
- Where
- 14 sites in Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Post-operative Sore Throat, Intubation Intratracheal
Effect of Tramadol on Postoperative Sore Throat After General Anesthesia
Post operative sore throat after general anesthesia with endotracheal intubation is a common problem causing dissatisfaction and discomfort to the patients.
- Conditions
- Post-operative Sore Throat, Intubation Intratracheal, Thyroid Surgery
- Trial name
- NCT04991493
- Testing
- Tramadol hydrochloride, Normal Saline
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Affiliated Cancer Hospital of Shantou University Medical College
Acute Pain
Effect of Nerve Block Versus General Anaesthesia for Distal Radial Fracture Surgery
This study aims to investigate whether infraclavicular nerve block improves acute postoperative pain after distal radial fracture surgery.
- Trial name
- NCT03048214
- Testing
- Infraclavicular nerve block, General anaesthesia
- Where
- Hong Kong
- Volunteers
- 52 people
- Sponsor
- The University of Hong Kong