Clinical trials: Glucosamine
Oral Lichen Planus
Efficacy of Topical Glucosamine Versus Corticosteroid in Oral Lichen Planus
Glucosamine (GlcN) is an N-deacetyl amino sugar derived from the complete hydrolysis of chitosan. It is classified as a nutraceutical and it is used mainly orally for the therapy of osteoarthritis since GlcN has immunoregulatory…
- Trial name
- NCT07114016
- Testing
- Glucosamine Hydrochloride, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Future University in Egypt
Osteoarthritis, Knee
Non-inferiority Study of the Glucosamine Sulfate + Chondroitin Sulfate Association Capsule in Comparison to the CONDROFLEX® Product in Osteoarthrosis of the Knee
This is an open, prospective, randomized, controlled, parallel, multicenter, non-inferiority study in 250 individuals (125 individuals per group), with 204 evaluable patients with clinical and radiological diagnosis of…
- Trial name
- NCT01172249
- Testing
- Glucosamine sulfate + chondroitin sulfate - MANTECORP, Glucosamine sulfate + chondroitin sulfate - CONDROFLEX
- Volunteers
- 250 people
- Sponsor
- Mantecorp Industria Quimica e Farmaceutica Ltd.
Osteoarthritis, Glucosamine
Clinical Efficacy of Glucosamine Plus Diacerein Versus Mono-therapy of Glucosamine
The purpose of this study is to compare pain scores, WOMAC total and subscores, actual and change of joint space width and the rate of gastrointestinal side effects at 4, 8, 12, and 24 weeks between dual-therapy of diacerein and…
- Conditions
- Osteoarthritis, Glucosamine, Diacerein
- Trial name
- NCT01906801
- Testing
- Glucosamine sulfate, Diacerein
- Where
- Thailand
- Volunteers
- 148 people
- Sponsor
- Ramathibodi Hospital
Osteoarthritis of the Knee
Effects of Aquamin F on Osteoarthritis of the Knee
The objective of this trial is to evaluate the effect of Aquamin F alone or in combination with glucosamine sulfate versus placebo on symptoms of joint pain, stiffness and immobility in subjects with painful osteoarthritis of the…
- Trial name
- NCT00452101
- Testing
- Aquamin F
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Marigot Ltd.
Knee Osteoarthritis
Effects of Glucosamine and Chondroitin Supplementation in Women With Knee Osteoarthritis Participating in an Exercise and Weight Loss Program
Background: Exercise, weight loss, and dietary supplementation of glucosamine and chondroitin (GC) have been reported to improve functional capacity in individuals with knee osteoarthritis (OA).
- Trial name
- NCT01271218
- Testing
- Diet, Exercise
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas A&M University
Osteo Arthritis of the Knees
Effect of Interventions on the Progression of Knee Osteoarthritis
There has been intensive search for a substance that can have disease-modifying activity for osteoarthritis. A number of medications have been reported to be of benefit on slowing progression of knee OA.
- Trial name
- KAPS (NCT02178137)
- Testing
- Diacerien, Glucosamine/Chondroitin
- Where
- Pakistan
- Volunteers
- 322 people
- Sponsor
- Indus Hospital and Health Network
Intraocular Pressure Changes After Glucosamine Sulfate Consumption.
Effect of Glucosamine on Intraocular Pressure
In this double blind clinical trial 92 patients suffering from rheumatoid arthritis are included. Those with the history of intraocular and corneal surgery, diabetic and heavy smokers are excluded from the study.
- Trial name
- NCT02306083
- Testing
- glucosamine sulfate 1500 mg three times a day
- Where
- Iran
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Knee Osteoarthritis
Effects of Glucosamine on Joint Fluid in Osteoarthritis Patients
Osteoarthritis (OA) is the most common joint disease associated with aging. Although many patients take glucosamine supplements as a non-traditional treatment for osteoarthritis, the effectiveness of these supplements is…
- Trial name
- NCT01074476
- Testing
- Glucosamine sulphate
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Knee Osteoarthritis
Effects of Creatine Supplementation as Compared to Glucosamine/Chondroitin Sulfate Supplementation in Addition to Exercise and Physical Therapy in the Management of Knee Osteoarthritis.
Osteoarthritis (OA) is one of the most common joint disorders, affecting not only the joints but also the surrounding muscles, which become weak.
- Trial name
- NCT04665804
- Testing
- Creatine Supplementation, Glucosamine and Chondroitin sulfate supplementation, Supervised Exercise training
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Knee Osteoarthritis, Knee Arthritis
Chitosan Versus Glucosamine Phonophoresis in the Management of Knee Osteoarthritis
The study will be conducted to answer the following questions: Is there an effect of phonophoresis using glucosamine on pain level , function and range of motion in knee osteoarthritis patients ? Is there an effect of…
- Trial name
- NCT05420441
- Testing
- Phonophoresis with chitosan, Phonophoresis with glucoasmine, Conventional Physical Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Aging
VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements
This study aims to assess the safety and efficacy of study drugs and supplements on clinical (structural and functional) signs of aging and to explore/identify other possible biological measures of aging.
- Trial name
- NCT04994561
- Testing
- Study Drugs and Nutritional Supplements
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vitality in Aging Research Group, Inc.
Knee Osteoarthritis
The Marigot Osteoarthritis Nutritional Intervention (MOANi) Trial
The purpose of the study is to test 30 individuals with mild-moderate knee joint osteoarthritis to investigate whether the combination of Aquamin (a calcium-rich marine multi-mineral) and a polyphenol-rich pine bark extract…
- Trial name
- MOANi (NCT03106584)
- Testing
- Aquamin-Plus, Glucosamine sulphate
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Type 1 Diabetes
Reactive Oxygen Species in the Pathogenesis of Diabetic Complications
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy and incipient nephropathy in these models.
- Trial name
- NCT00703989
- Testing
- benfotiamine, α-lipoic acid
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Osteoarthritis of the Knee
A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee.
The primary objective of the study is to assess the effectiveness of alpha-D Glucosamine Sulfate/Standardized Extract of Ginkgo Biloba Leaf versus a comparator product on osteoarthritis pain as assessed by the between group…
- Trial name
- 13GOHJ (NCT02604381)
- Testing
- Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Extract
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- KGK Science Inc.
Oral Lichen Planus
Glucosamine as a Novel Adjunctive Therapy in Oral Lichen Planus
Glucosamine (GlcN) is an N-deacetyl amino sugar derived from the complete hydrolysis of chitosan with recently reported immunoregulatory capacity and anti-inflammatory effect and was administrated orally in osteoarthritis and…
- Trial name
- NCT02858297
- Testing
- Glucosamine sulfate, triamcinolone acetonide
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Knee Osteoarthritis
GLUCOSAMINE/CHONDROITIN and PHYSICAL THERAPY EFFECTS ON OLDER POPULATION WITH KNEE OSTEOARTHRITIS
to see the effect of glucosamine chondratin sulfate with and without physiotherapy in knee osteoarthritis
- Trial name
- NCT05321836
- Testing
- Glucosamine Chondroitin, glucosamine chondritin & Physiotherapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Muhammad salman, PT
Knee Osteoarthritis
Efficacy and Safety of a New Formulation of Chondroitin Sulfate and Glucosamine Sulfate to Treat Knee Osteoarthritis
The main objective is to assess the efficacy of a new formulation containing chondroitin sulfate and glucosamine sulfate (CS+GS) compared with placebo in patients with primary osteoarthritis of the knee.
- Trial name
- NCT01893905
- Testing
- CS+SG
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Tedec-Meiji Farma, S.A.
Inflammation
Glucosamine and Chondroitin Effects
A common starting dose of glucosamine and chondroitin will reduce inflammation as reflected by a reduction in serum C-reactive protein.
- Trial name
- GLANCE (NCT01682694)
- Testing
- Glucosamine and Chondroitin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Knee Osteoarthritis
Intra-articular Viscosupplement Application in Knee Osteoarthritis
Knee osteoarthritis (OA) is one of the common diseases which causes pain and disability with increasing age. In developed countries, it is said to be one of the ten diseases which decreases functionality most.
- Trial name
- NCT03913052
- Testing
- Intra-articular Viscosupplement Application
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul Bilgi University
Hereditary Inclusion Body Myopathy, Distal Myopathy With Rimmed Vacuoles
A Study to Evaluate the Safety of Aceneuramic Acid Extended Release (Ace-ER; UX001) Tablets in Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy (GNEM) (Also Known as Hereditary Inclusion Body Myopathy [HIBM]) Patients With Severe Ambulatory Impairment
The primary objective of this Phase 2 study is to evaluate the safety of open-label 6 g/day Ace-ER in GNEM participants with severe ambulatory impairment.
- Conditions
- Hereditary Inclusion Body Myopathy, Distal Myopathy With Rimmed Vacuoles, Distal Myopathy, Nonaka Type, GNE Myopathy
- Trial name
- NCT02731690
- Testing
- Aceneuramic Acid Extended-Release
- Where
- 5 sites in United States, Bulgaria and 1 more
- Volunteers
- 42 people
- Sponsor
- Ultragenyx Pharmaceutical Inc