Clinical trials: Glucose Control
Diabetes, Healthy
Comparing Semaglutide Administered Subcutaneously Once Daily to Semaglutide Administered Subcutaneously Once Weekly
This trial is conducted in Europe. The aim of this trial is to compare the steady-state exposure of semaglutide administered subcutaneously once daily to semaglutide administered subcutaneously once weekly in healthy subjects.
- Trial name
- NCT02557620
- Testing
- semaglutide
- Where
- Germany
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus, Healthy
Modulation of Human Myocardial Metabolism by GLP-1 Dose Response
The objective of this proposal is to provide quantitative dose-response data for effects of GLP-1 on myocardial glucose uptake in healthy control subjects and obese type 2 diabetic subjects, in support of the design of later…
- Trial name
- NCT01607450
- Testing
- GLP-1 Low Dose, GLP-1 Mid-Range Dose, GLP-1 High Dose
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Indiana University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Type 2 Diabetes Mellitus
A Two-Part, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DS-7309 in Healthy Volunteers and Subjects With Type 2 Diabetes Mellitus
This is a randomized, placebo-controlled, 2-part, sequential, single ascending dose study. Part 1 is planned as 6 sequential escalation treatment groups.
- Trial name
- NCT01862939
- Testing
- DS-7309
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo
Cancer, Breast, Cancer, Ovarian
Family History App in Personalized Medicine
A complete family history (FH) may identify persons at high risk for certain conditions. They can be offered genetic testing and life-saving screening and treatment.
- Conditions
- Cancer, Breast, Cancer, Ovarian, Cancer, Colorectal, Cancer, Prostate
- Trial name
- FHAMe (NCT04726319)
- Testing
- FHAMe Intervention
- Where
- Canada
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Gestational Diabetes, GDM
The MalaYsian GestatiOnal Diabetes and Prevention of DiabetES Study
Gestational diabetes mellitus (GDM) is an increasingly common condition of pregnancy and is associated with adverse foetal, infant, and maternal outcomes.
- Conditions
- Gestational Diabetes, GDM, Pregnancy-Induced Diabetes
- Trial name
- MyGODDESS (NCT05204706)
- Testing
- MyManis app
- Where
- 3 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Asthma, Diabetes Mellitus
A Study Designed to Determine if the Pharmacokinetic Disposition of Inhaled Insulin Exposure is the Same for Asthmatics and Non-asthmatics
This study will compare the rate and extent of absorption of TI Inhalation Powder in subjects with asthma and subjects with normal lung function. 24 eligible subjects will be enrolled into the treatment phase of the trial.
- Trial name
- NCT00673621
- Testing
- Technosphere Insulin Inhalation Powder, Salbutamol (Albuterol), Methacholine chloride
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Type II Diabetes
Effectiveness of an mHealth Mobile App
Type II diabetes is a serious challenge for Pakistan. Not using medications properly increases healthcare costs and diabetes-related deaths.
- Trial name
- mHealth (NCT06387433)
- Testing
- mobile app use
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Diabetes Mellitus
To Evaluate the Safety, Tolerability, and Pharmacokinetics of YG1699（Antidiabetic） in Healthy Chinese Sbjects
This is a randomized, double-blind, placebo-controlled, single ascending dose (SAD) and multi-dose, sequential, bridging study in healthy volunteer using YG1699 .
- Trial name
- NCT05089617
- Testing
- YG1699
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Youngene Therapeutics Inc., Ltd.
Type 1 Diabetes
Investigation of the Skin Barrier in Patients With Type 1 Diabetes
This study is a case-control study comparing the skin barrier between 50 T1D patients with healthy controls in 3 age-strata including both pediatric and adult patients.
- Trial name
- NCT04280315
- Where
- 2 sites in Denmark
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Jannet Svensson
Diabetes Mellitus, Type 2
A Study Designed to Determine the Safety and Pharmacological Response ofMKC253 Inhalation Powder in Adults With Type 2 Diabetes Mellitus
20 eligible subjects will be enrolled into the treatment phase of the trial.
- Trial name
- NCT00642538
- Testing
- MKC253 Inhalation Powder, Technosphere Inhalation Powder, subcutaneous injection
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Taurine, Aging, Biological
Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men
The goal of this clinical trial is to investigate the effect of taking 4 grams of taurine by older adults on aging processes over a period of 6 months.
- Conditions
- Taurine, Aging, Biological, Physical Activity, Metabolic Health
- Trial name
- TauAge (NCT06613542)
- Testing
- 4g of taurine daily
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Obesity, Morbid Obesity
Long Term Effect of Very-low-calories Ketogenic Diet on Weight Control and Cardiovascular Brisk Factors (KETOHEART)
The growing obesity pandemic has a major impact on global cardiovascular (CVD)-related morbidity and premature mortality, severely compromising the quality of life of those affected and significantly increasing costs for the…
- Trial name
- KETOHEART (NCT05781269)
- Testing
- VLCKD, r-MedDiet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Diabetes Mellitus, Obesity
Study of the Gut Hormone Analogue Y14 in Adult Subjects
A randomised, placebo controlled Phase I study to investigate investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of Y14 in adult subjects.
- Trial name
- NCT03673111
- Testing
- Y14
- Where
- United Kingdom
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Eating Almonds Before a Meal to Control Blood Sugar
The goal of this study is to learn whether eating a small serving of almonds before meals can improve blood sugar control in adults who have early signs of problems with blood sugar regulation.
- Conditions
- Glucose Control, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Precision Medicine, Nutrition
- Trial name
- NUTS (NCT07603739)
- Testing
- Premeal almond ingestion
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes Mellitus
NOX-E36 Multiple Ascending Dose Study in Healthy Volunteers and Patients With Type 2 Diabetes Mellitus
The primary objective of this trial is to evaluate the safety and tolerability of multiple intravenous doses of NOX-E36 in healthy subjects and patients with type 2 diabetes mellitus.
- Trial name
- NCT01085292
- Testing
- NOX-E36
- Where
- 5 sites in Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- TME Pharma AG
Physical Activity, Healthy
The Effects of Dietary Intake of Cod Residual Material Meal on Lipid Regulation, Glucose Regulation and Body Composition in Physically Active Adults
A high intake of fish is associated with positive health effects, including prevention and treatment of chronic non-communicable diseases, such as cardiovascular diseases (CVDs) and type 2 diabetes.
- Trial name
- COD2016 (NCT03538834)
- Testing
- Cod meal from residual material, Control
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Type 2 Diabetes Mellitus
Diabetes Prevention and Control in the Workplace: A Pilot Study
This worksite program for Onondaga County employees is a pilot research study aimed at decreasing the risk of developing diabetes (or improving metabolic control for adults with diabetes).
- Trial name
- NCT00739336
- Testing
- Diabetes Prevention and Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Healthy, Overweight and Obesity
Strategies To OPpose Sugars With Non-nutritive Sweeteners Or Water (STOP Sugars NOW) Trial
Health authorities recommend a reduction in added sugars from sugar-sweetened beverages (SSBs) due to risk of obesity and diabetes. As a sugar-reduction strategy, finding the ideal SSB replacement is of the utmost importance.
- Conditions
- Healthy, Overweight and Obesity, Metabolic Syndrome, PreDiabetes
- Trial name
- NCT03543644
- Testing
- Sugar-sweetened beverage (SSB), Non-nutritive sweetened beverages (NSB), Water
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Postprandial Hyperglycemia
Investigation of Milk Peptides on Postprandial Blood Glucose Profile
Aim of the study is to investigate the effect of two different dosages of milk peptides on postprandial blood glucose profile in prediabetic subjects compared to placebo.
- Trial name
- NCT03932695
- Testing
- Low dose milk peptide, High Dose milk peptide
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ingredia S.A.
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