Clinical trials: Glucose Control
Obesity, Diabetes
Impaired Gustatory Sensory Perception in Obese and Obese Diabetic Persons
The aim of the study is to compare several parameters in three distinct groups of subjects: persons with obesity, persons with obesity and diabetes and persons with neither obesity nor diabetes: the electrical activity in…
- Trial name
- PEGASE (NCT03228602)
- Testing
- Recording of GEP (Gustatory Evoked Potentials)
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Faba Bean, Post-prandial Blood Glucose
Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control
To describe the effect and mechanisms of action faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years).
- Conditions
- Faba Bean, Post-prandial Blood Glucose, Appetite, Satiety Hormones
- Trial name
- NCT02666586
- Testing
- Faba bean powder smoothie, Faba bean protein concentrate smoothie, Faba bean starch smoothie
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Type 2 Diabetes
IDG-16177 for the Evaluation of Its Safety and Pharmacokinetics
This is a Phase I, first-in-human, randomised, double-blinded, placebo-and active-controlled study to assess the safety, tolerability, PK, PD, efficacy, and food-effect of IDG-16177 in healthy male subjects and patients with T2DM…
- Trial name
- NCT04982705
- Testing
- [Part 1.1] IDG-16177, [Part 2] Sitagliptin, [Part1.2] IDG-16177
- Where
- Germany
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Diabetes Mellitus
Safety and Tolerability of GX-G6 in Healthy Male Subjects
This study is a single-center, double-blind, placebo-controlled, phase I study with healthy male subjects receiving ascending single s.c. doses of GX-G6
- Trial name
- NCT03651466
- Testing
- Gx-G6
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Genexine, Inc.
Diabetes Mellitus, Cardiomyopathy
B-type Natriuretic Peptide and Glucose Metabolism
Rationale: B type natriuretic peptide (BNP) is a hormone released from cardiomyocytes in response to myocyte stretching and serves as a reliable biomarker in the diagnosis of cardiac dysfunction and heart failure.
- Trial name
- NCT01324739
- Testing
- human BNP-32
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Sleep Disorders, Circadian Rhythm
Circadian Phase Adjustment and Improvement of Metabolic Control in Night Shift Workers
EuRhythDia II is a multicenter, randomized, double-blind controlled study. The rationale of EuRhythdia is to explore the effects of 12 weeks of timed melatonin treatment on circadian rhythm, metabolic control and cardiovascular…
- Trial name
- NCT02108353
- Testing
- Melatonin 2mg
- Where
- 3 sites in Germany, Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Diabetic Foot, Educational Intervention
Effectiveness of Educational Intervention on Footcare Among Individuals Having Type 2 Diabetes at Slums of Karachi, Pakistan.
There are multiple studies conducted in Pakistan that supports the topic of foot care knowledge among individual with type 2 diabetes but all are descriptive cross-sectional studies and investigators cannot develop cause effect…
- Conditions
- Diabetic Foot, Educational Intervention, Foot Care, Foot Ulcer, Diabetic
- Trial name
- NCT06358846
- Testing
- Self-care behavior to promote foot care through educational guidance among individual with diabetes
- Where
- Pakistan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SINA Health Education and Welfare Trust
Blood Pressure
The Effect of Eating Frequency on Blood Pressure
The primary purpose of this study is to identify the effect of meal frequency on blood pressure (BP) levels of individuals.
- Trial name
- NCT01640015
- Testing
- dietary intervention
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity
To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes
This study is the first administration of GSK2890457 in humans. The study will be conducted in 3 parts: - Part A (conducted at a single investigative site) will determine the safety and tolerability of GSK2890457 alone in healthy…
- Trial name
- NCT01725126
- Testing
- GSK2890457, Metformin, Liraglutide
- Where
- 3 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Non-alcoholic Fatty Liver Disease
Effect of Supplementation of Fish Oil on Non-alcoholic Fatty Liver Disease in Children
The aim of this study is to evaluate efficacy of fish oil (EPA/DHA) in children with non-alcoholic fatty liver disease.
- Trial name
- NCT01547910
- Testing
- Fish Oil
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Piotr Socha
Gastrointestinal Hormones, Glycemic Control
Assessments of Metabolic Responses to Acute Oral Administration of Sucrose, Glucose, and Fructose
This project aims to compare the acute metabolic effects of the three sweeteners sucrose, glucose, and fructose on GI hormones (GLP-1, PYY, CCK, GIP, and ghrelin).
- Conditions
- Gastrointestinal Hormones, Glycemic Control, Blood Coagulation Function, Gastric Emptying
- Trial name
- NCT06799715
- Testing
- Sucrose, Glucose, Fructose
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Effect of Chronic Leucine Supplementation on Glucose Homeostasis, Lipid Profile, Body Composition, and Muscle Mass and Strenght
Effects of Chronic Leucine Supplemetion on Glucose Homeostasis, Body Compositin, Muscle Mass and Strength of Healthy and Young Subjects
This study aims to evaluate the effects of chronic leucine supplemetion on glucose homeostasis, body compositin, muscle mass and strength of healthy and young subjects
- Trial name
- NCT01496768
- Testing
- Leucine, Alanine
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Metabolic Syndrome, Obesity
An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer
Among African-American women, in whom metabolic syndrome (MetS) is very prevalent and breast cancer mortality rates are high, it is hypothesized that intervening on MetS to improve the MetS profile may prove to be a means to…
- Trial name
- NCT02103140
- Testing
- Facility-based Exercise, Home-based Exercise
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Type 2 Diabetes Mellitus, Healthy
Modulation of Human Myocardial Metabolism by GLP-1 Dose Response
The objective of this proposal is to provide quantitative dose-response data for effects of GLP-1 on myocardial glucose uptake in healthy control subjects and obese type 2 diabetic subjects, in support of the design of later…
- Trial name
- NCT01607450
- Testing
- GLP-1 Low Dose, GLP-1 Mid-Range Dose, GLP-1 High Dose
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pre Diabetes
Effects of Fos Biomedical Device on Diabetes Risk Factors and Sleep Quality in Adults at Risk for Type 2 Diabetes
Purpose Phototherapy has an array of potential benefits in human health. The effects of a non-transdermal Fos Biomedical product (which utilizes the concept of phototherapy) on diabetes risk factors and sleep quality in people at…
- Trial name
- NCT05628597
- Testing
- Fos Biomedical patch product
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Griffin Hospital
Diabetes Mellitus
Study of Efficacy and Tolerability of Various Bowel Preps in Diabetic Patients
Poor bowel preparation and patient intolerance of the procedure are the most important factors contributing to the limitation of colonoscopy.
- Trial name
- NCT01533688
- Testing
- split dose of Golytely (polyethylene glycol electrolyte lavage solution) and bisacodyl
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Obesity, Morbid Obesity
Long Term Effect of Very-low-calories Ketogenic Diet on Weight Control and Cardiovascular Brisk Factors (KETOHEART)
The growing obesity pandemic has a major impact on global cardiovascular (CVD)-related morbidity and premature mortality, severely compromising the quality of life of those affected and significantly increasing costs for the…
- Trial name
- KETOHEART (NCT05781269)
- Testing
- VLCKD, r-MedDiet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Type 2 Diabetes Mellitus
Assessment of Gastric Emptying by SHR20004 in Healthy Subjects
The purpose of this study is to investigate the impact of SHR20004 on the pharmacokinetic (PK) characteristics of acetaminophen in healthy subjects.
- Trial name
- NCT06137469
- Testing
- Acetaminophen/SHR20004
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Cardiometabolic Syndrome, Glucose Metabolism Disorders
The Effect of Flexitarian, Time-restricted Eating on Cardiometabolic Traits in Normal Weight, Young Men
The goal of this factorial randomized controlled trial is to find out whether time-restricted eating and flexitarian diet (on its own and combined) can improve cardiometabolic health markers in normal weight, young men with…
- Conditions
- Cardiometabolic Syndrome, Glucose Metabolism Disorders, Blood Pressure, Lipid Metabolism Disorders
- Trial name
- FlexiFast (NCT05762263)
- Testing
- Dietary
- Where
- Poland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury in Olsztyn
Intermittent Fasting in Shift-work
Time-restricted Eating and Circadian Health in Night Shift Workers
The goal of this clinical trial is to learn about the effect of time-restricted eating (TRE) to 10 hours per day on glucose homeostasis, markers of the circadian system, homeostatic and hedonic regulation of appetite, and…
- Trial name
- FastingClocks (NCT07451132)
- Testing
- Time-restricted eating
- Where
- Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Chile
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